IL-4 signaling pathway (Danio rerio)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none TranslocationCytoplasmPlasma membraneNucleusCY -> NUDDDDCY -> PMCY -> PMCY -> PMCY -> PMCY -> NUDDDLigandReceptorMolecule in the pathwayDInhibitionDAccession Number: NetPath 16Proteins in a complex interactionMolecular associationReaction through unknown mechanisms/moleculesPhosphorylationDephosphorylationActivation(Protein-protein interaction)AcetylationPMCYNUEnzyme complexAutophosphorylationDeacetylationGlycosylationMethylationDemethylationPalmitoylationProteolytic cleavageSumoylationDesumoylationUbiquitinationDeubiquitinationRecruitmentECExtracellularENEndosomeEndoplasmic reticulumERGolgi apparatusGOMitochondrionMTControlIL2RGIL4RIL4FESLOC559103ptpn6ptpn11jak1LOC559281IL4IL4RIL13RA1jak2bTYK2jak1LOC557176pik3r2prkczLOC566983pawrlIRS2JAK3grb2SOS1CXCR4adrbk2ptk2.1LOC563639plcg1HIST2H3Ccrebbpbep300amapk14azgc:86905atf2lcblLOC566983LOC566983STAT5ASOCS5LOC566983mapk1mapk3mapk14aDOK2rasa1NFKB1relaBADNCF1LOC561737pik3cdbcl2lsocs1rps6kb1HMGA1ets1aSOCS3stat1asrcLOC567895LOC792354PRKCDLOC557337prkciPRKCDLOC557337prkciprkczNFKB1spi1LCKfynbstamLOC566983jak2bGene SymbolName: IL-4 signaling pathwayOrganism: Danio rerio


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP395(r28126) with a 66% conversion rate.

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Quality Tags

Image:Unconnected.pngFix interactions
Image:NeedsRef.pngAdd references
Image:Curated.pngApproved version
Image:MissingDescription.pngAdd description
Image:MissingXref.pngAnnotate nodes
Homology Converted

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117985
Approved
view11:23, 23 May 2021EweitzModified title
86930view13:05, 15 July 2016MkutmonOntology Term : 'interleukin-4 signaling pathway' added !
68697view05:59, 6 July 2013MaintBotUpdated to 2013 gpml schema
40873view22:21, 1 March 2011MaintBotRemoved redundant pathway information and comments
34253view21:45, 9 December 2009MaintBotAutomatic update of empty xrefs
31384view20:42, 13 August 2009MaintBotFixed text labels
31088view01:35, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
BADGeneProduct58100 (Entrez Gene)
CXCR4GeneProduct
DOK2GeneProduct
FESGeneProduct
Gene SymbolGeneProduct
HIST2H3CGeneProduct
HMGA1GeneProduct
IL13RA1GeneProduct799475 (Entrez Gene)
IL2RGGeneProduct
IL4GeneProduct
IL4RGeneProduct503594 (Entrez Gene)
IRS2GeneProduct
JAK3GeneProduct561370 (Entrez Gene)
LCKGeneProduct414333 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC557337GeneProduct557337 (Entrez Gene)
LOC559103GeneProduct559103 (Entrez Gene)
LOC559281GeneProduct559281 (Entrez Gene)
LOC561737GeneProduct561737 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC566983GeneProduct566983 (Entrez Gene)
LOC567895GeneProduct567895 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
NCF1GeneProduct378966 (Entrez Gene)
NFKB1GeneProduct565756 (Entrez Gene)
PRKCDGeneProduct334571 (Entrez Gene)
SOCS3GeneProduct
SOCS5GeneProduct
SOS1GeneProduct
STAT5AGeneProduct
TYK2GeneProduct
adrbk2GeneProduct569403 (Entrez Gene)
atf2lGeneProduct100006516 (Entrez Gene)
bcl2lGeneProduct114401 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
crebbpbGeneProduct503776 (Entrez Gene)
ep300aGeneProduct559273 (Entrez Gene)
ets1aGeneProduct280651 (Entrez Gene)
fynbGeneProduct574422 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
jak1GeneProduct30280 (Entrez Gene)
jak2bGeneProduct30298 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk14aGeneProduct65237 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
pawrlGeneProduct449994 (Entrez Gene)
pik3cdGeneProduct394174 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
plcg1GeneProduct373867 (Entrez Gene)
prkciGeneProduct117507 (Entrez Gene)
prkczGeneProduct555737 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
rasa1GeneProduct100002155 (Entrez Gene)
relaGeneProduct415099 (Entrez Gene)
rps6kb1GeneProduct406349 (Entrez Gene)
socs1GeneProduct445073 (Entrez Gene)
spi1GeneProduct30117 (Entrez Gene)
srcGeneProduct325084 (Entrez Gene)
stamGeneProduct386967 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
zgc:86905GeneProduct415185 (Entrez Gene)

Annotated Interactions

No annotated interactions
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