Biosynthesis and regulation of nematode bile acids (Caenorhabditis elegans)

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DAF-9CholesterolDAF-36DHS-16HSD-1EMB-8Δ4-Dafachronic Acid1, 27-DehydrocholesterolLathosterolLathosteroneΔ7-Dafachronic AcidDafachronic acidCholestenoneEMB-8DAF-9


Description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Rottiers V, Motola DL, Gerisch B, Cummins CL, Nishiwaki K, Mangelsdorf DJ, Antebi A; ''Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase.''; Dev Cell, 2006 PubMed Europe PMC Scholia
  2. Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, Mangelsdorf DJ, Cummins CL, Antebi A; ''The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity.''; Aging Cell, 2011 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
106026view11:55, 16 August 2019MaintBotHMDB identifier normalization
84472view19:28, 25 February 2016AlexanderPicoQuick edit to datanode annotation or property
84471view19:27, 25 February 2016AlexanderPicoQuick edit to datanode annotation or property
84470view19:26, 25 February 2016AlexanderPicoQuick edit to datanode annotation or property
84469view19:26, 25 February 2016AlexanderPicoQuick edit to datanode annotation or property
73760view00:10, 22 February 2014MaintBotupdating schema
71816view19:02, 18 October 2013EgonwAdded a metabolite ID.
67089view10:04, 26 June 2013Christine ChichesterOntology Term : 'bile acid biosynthetic pathway' added !
58830view23:23, 20 February 2013MaintBot
53114view01:31, 30 October 2012MaintBotModified categories
51240view12:01, 3 September 2012AnweshaAdded literature refernces to DHS-16
51239view11:52, 3 September 2012AnweshaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
7-DehydrocholesterolMetaboliteHMDB0000032 (HMDB)
CholestenoneMetaboliteHMDB0000921 (HMDB)
CholesterolMetaboliteHMDB0000067 (HMDB)
DAF-36GeneProductWBGene00007536 (Ensembl)
DAF-9GeneProductT13C5.1 (Ensembl)
DAF-9GeneProductWBGene00000905 (Ensembl)
DHS-16GeneProductWBGene00000979 (WormBase)
Dafachronic acidMetabolite
EMB-8GeneProductWBGene00001262 (Ensembl)
HSD-1ProteinY6B3B.11 (WormBase)
LathosterolMetaboliteHMDB0001170 (HMDB)
LathosteroneMetaboliteCHEBI:71550 (ChEBI)
Δ4-Dafachronic AcidMetabolite
Δ7-Dafachronic AcidMetabolite

Annotated Interactions

No annotated interactions

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