Osteoblast signaling (Mus musculus)
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Description
Osteoblasts are specialized, terminally differentiated uninucleated cells responsible for bone formation. Their activity is tightly regulated by external stimuli, originating from e.g. the parathyroid glands, osteocytes, etc.
Along with osteoclasts, which are responsible for bone degradation, osteoblasts are key regulators of the shape and volume of bone tissue.
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Ontology Terms
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DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Bone sialoprotein | GeneProduct | 12907 (Entrez Gene) ![]() | |
Collagen 1 | GeneProduct | 12842 (Entrez Gene) ![]() | |
FGF-23 | GeneProduct | 64654 (Entrez Gene) ![]() | |
NPT3 | GeneProduct | 218103 (Entrez Gene) ![]() | |
Osteocalcin | GeneProduct | 12097 (Entrez Gene) ![]() | |
Osteoprotegerin | GeneProduct | 18383 (Entrez Gene) ![]() | |
PDGF Ra | GeneProduct | 18595 (Entrez Gene) ![]() | |
PDGF Rb | GeneProduct | 18596 (Entrez Gene) ![]() | |
PDGF-BB | GeneProduct | ||
PTH receptor | GeneProduct | 19228 (Entrez Gene) ![]() | |
Parathyroid hormone | GeneProduct | 19226 (Entrez Gene) ![]() | |
Phosphate | Metabolite | HMDB0001429 (HMDB) ![]() | |
RANK ligand | GeneProduct | 21943 (Entrez Gene) ![]() | |
Sodium | Metabolite | HMDB0000588 (HMDB) ![]() | |
Soluble RANK ligand | GeneProduct | ||
Vitamin D | GeneProduct | ||
avb3 integrin | GeneProduct |
Annotated Interactions
No annotated interactions