Integrated cancer pathway (Bos taurus)

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1, 432BASC ComlexPUMAMIR29B1ATF1MDM2E2F1CHEK2TP53NOXA1BCL2CDKN2BCASP9AKT1MIR29CBRCA1MYCSTAT1MAP3K5CDC25BMRE11ADNA-PKCDKN1AJAK1BADQ8NBS1_HUMANCDK1BAXCctlpp38ATRSMAD2CDC25ARB1BACH1PTENCASP8CASP3MSH2CDK4_HUMANSwi/SNFSMAD3BARD1CDK2BRCA1CHEK1p13Kbta-mir-21p14RAD50POU2F1MSH6BLMCDKN1BMMP1ATMMIR29B2PLK1


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP1971(80447) with a 81.0% conversion rate.

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Bibliography

  1. Zhao JJ, Lin J, Lwin T, Yang H, Guo J, Kong W, Dessureault S, Moscinski LC, Rezania D, Dalton WS, Sotomayor E, Tao J, Cheng JQ; ''microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma.''; Blood, 2010 PubMed Europe PMC Scholia
  2. Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS, Krichevsky AM; ''MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.''; Mol Cell Biol, 2008 PubMed Europe PMC Scholia
  3. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T; ''MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.''; Gastroenterology, 2007 PubMed Europe PMC Scholia
  4. Wang C, Bian Z, Wei D, Zhang JG; ''miR-29b regulates migration of human breast cancer cells.''; Mol Cell Biochem, 2011 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
117557view11:18, 21 May 2021EweitzModified title
80873view15:29, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1ProteinENSBTAG00000017636 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P31749
ATF1GeneProductENSBTAG00000018131 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000123268
ATMProteinENSBTAG00000003111 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q13315
ATRProteinENSBTAG00000011529 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q13535
BACH1GeneProductENSBTAG00000004139 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000156273
BADProteinENSBTAG00000012511 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q92934
BARD1ProteinENSBTAG00000033690 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q99728
BAXProteinENSBTAG00000013340 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q07812
BCL2ProteinENSBTAG00000019302 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P10415
BLMProteinENSBTAG00000020301 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P54132
BRCA1ProteinENSBTAG00000022520 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P38398
CASP3ProteinENSBTAG00000015874 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P42574
CASP8ProteinENSBTAG00000015718 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q14790
CASP9ProteinENSBTAG00000002472 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P55211
CDC25AGeneProductENSBTAG00000009586 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000164045
CDC25BGeneProductENSBTAG00000008436 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000101224
CDK1ProteinENSBTAG00000010109 (Ensembl)
  • Oncogene
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P06493
CDK2ProteinENSBTAG00000004021 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P24941
CDK4_HUMANProteinENSBTAG00000046091 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P11802
CDKN1AProteinENSBTAG00000008353 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1026
CDKN1BProteinENSBTAG00000018254 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1027
CDKN2BProteinENSBTAG00000016412 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1030
CHEK1ProteinENSBTAG00000017582 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:O14757
CHEK2ProteinENSBTAG00000004956 (Ensembl)
  • Phosphrylated
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:O96017
CctlpProtein
DNA-PKMetabolite
E2F1ProteinENSBTAG00000003971 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q01094
JAK1ProteinENSBTAG00000003147 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P23458
MAP3K5ProteinENSBTAG00000009065 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4217
MDM2ProteinENSBTAG00000010422 (Ensembl)
  • Oncogene
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q00987
MIR29B1Rna
MIR29B2Rna
MIR29CRna
MMP1ProteinENSBTAG00000048029 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P03956
MRE11AProteinENSBTAG00000008925 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P49959
MSH2ProteinENSBTAG00000002742 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P43246
MSH6ProteinENSBTAG00000001424 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P52701
MYCGeneProductENSBTAG00000008409 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000136997
NOXA1ProteinENSBTAG00000012121 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q86UR1
PLK1GeneProductENSBTAG00000014453 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166851
POU2F1ProteinENSBTAG00000024534 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5451
PTENProteinENSBTAG00000009498 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P60484
PUMAProtein
Q8NBS1_HUMANProtein
RAD50ProteinENSBTAG00000011252 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q92878
RB1ProteinENSBTAG00000006640 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P06400
SMAD2ProteinENSBTAG00000039916 (Ensembl)
  • Tumor supressor
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:Q15796
SMAD3ProteinENSBTAG00000012599 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P84022
STAT1ProteinENSBTAG00000007867 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P42224
Swi/SNFProtein
TP53ProteinENSBTAG00000001069 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P04637
bta-mir-21RnaENSBTAG00000029897 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000199004
p13KProtein
p14Protein
p38Protein

Annotated Interactions

No annotated interactions
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