Insulin signaling in adipocytes (diabetic condition) (Homo sapiens)
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Description
The paper describes insulin signaling in human adipocytes under normal and diabetic states using mathematical models based on experimental data. This model corresponds to insulin signaling under diabetic condition. Insulin signaling under normal condition is represented in WP3634.
The model has been converted to GPML using the PathSBML plugin from PathVisio, importing the model BIOMD0000000449 from the BioModels Database directly. The layout has been improved manually.
Quality Tags
 | Approved version |
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Ontology Terms
Saving...Pathway Ontology : calcium/calmodulin dependent signaling pathway G protein mediated signaling pathway via Galphai family G protein mediated signaling pathway via Galphas family Ras superfamily mediated signaling pathway G protein mediated signaling pathway via Galphaq family endothelin signaling pathway
Disease : hypertension benign essential hypertension
Cell Type : smooth muscle cell blood vessel endothelial cell
Bibliography
- Brännmark C, Nyman E, Fagerholm S, Bergenholm L, Ekstrand EM, Cedersund G, Strålfors P; ''Insulin signaling in type 2 diabetes: experimental and modeling analyses reveal mechanisms of insulin resistance in human adipocytes.''; J Biol Chem, 2013 PubMed Europe PMC Scholia
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