Macrophage markers (Homo sapiens)

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Annotated lists Annotated lists of gene products are considered useful for analysis and for stimulating future pathway curation.

Approved version The current version of this pathway was approved for data analysis by Kristina Hanspers.

Annotate nodes Comment: 1 out of 10 DataNodes have a missing external reference. Check DataNode table at the bottom of the page. Please help improve this pathway by annotating gene, protein and metabolite nodes.

Homology Converted Comment: Inferred from another species Revision {{{tag_revision}}} of this pathway has been inferred from another species (tagged by Maintenance bot). Expression error: Unrecognised punctuation character "{"

Ontology Terms

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Bibliography

1. Brettschneider J, Ecker D, Bitsch A, Bahner D, Bogumil T, Dressel A, Elitok E, Kitze B, Poser S, Weber F, Tumani H; ''The macrophage activity marker sCD14 is increased in patients with multiple sclerosis and upregulated by interferon beta-1b.''; J Neuroimmunol, 2002 PubMed Europe PMC Scholia
2. Töröcsik D, Bárdos H, Nagy L, Adány R; ''Identification of factor XIII-A as a marker of alternative macrophage activation.''; Cell Mol Life Sci, 2005 PubMed Europe PMC Scholia
3. Kunz-Schughart LA, Weber A, Rehli M, Gottfried E, Brockhoff G, Krause SW, Andreesen R, Kreutz M; ''[The "classical" macrophage marker CD68 is strongly expressed in primary human fibroblasts].''; Verh Dtsch Ges Pathol, 2003 PubMed Europe PMC Scholia
4. Aperlo C, Sevilla L, Guerin S, Pognonec P, Boulukos KE; ''Synergistic effects of colony-stimulating factor 1 and leukemia inhibitory factor in inducing early myeloid cell differentiation.''; Cell Growth Differ, 1998 PubMed Europe PMC Scholia
5. Mahnke K, Becher E, Ricciardi-Castagnoli P, Luger TA, Schwarz T, Grabbe S; ''CD14 is expressed by subsets of murine dendritic cells and upregulated by lipopolysaccharide.''; Adv Exp Med Biol, 1997 PubMed Europe PMC Scholia
6. Lau SK, Chu PG, Weiss LM; ''CD163: a specific marker of macrophages in paraffin-embedded tissue samples.''; Am J Clin Pathol, 2004 PubMed Europe PMC Scholia
7. Hiraoka A, Horiike N, Akbar SM, Michitaka K, Matsuyama T, Onji M; ''Expression of CD163 in the liver of patients with viral hepatitis.''; Pathol Res Pract, 2005 PubMed Europe PMC Scholia
8. Fonseca JE, Edwards JC, Blades S, Goulding NJ; ''Macrophage subpopulations in rheumatoid synovium: reduced CD163 expression in CD4+ T lymphocyte-rich microenvironments.''; Arthritis Rheum, 2002 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
CD14	GeneProduct	ENSG00000170458 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12475
CD163	GeneProduct	ENSG00000177575 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:93671
CD68	GeneProduct	ENSG00000129226 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12514
CD74	GeneProduct	ENSG00000019582 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16149
CD83	GeneProduct	ENSG00000112149 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12522
CD86	GeneProduct	ENSG00000114013 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12524
Cd52	GeneProduct		No homologues found for original id L:23833
F3	GeneProduct	ENSG00000117525 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14066
LYZ	GeneProduct	ENSG00000090382 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17105
RAC2	GeneProduct	ENSG00000128340 (Ensembl)	Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19354

Annotated Interactions