Histidine, purine, and pyrimidine superpathway (Saccharomyces cerevisiae)

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H+reduced thioredoxinNH3H2OL-aspartateTHFH+L-aspartateH2Ocarbamoyl-phosphateH+H2OHCO3histidinolH2O5’-phosphoribosyl-4-(N-H2ONADH2Ocarbamoyl-L-aspartateH2Ophosphoribosyl-carboxy-aminoimidazole5’-phosphoribosyl-5-aminoimidazoleAMPphosphoribosyl-ATPH2OIMPsucinocarboxamide)-5-aminoimidazole5-phosphoribosylamineH2OUMPphosphoribosyl-formamido-carboxamideTHFAMPdeoxy-GTPCO2CO25’-phosphoribosyl-N-formylglycineamidephosphoribulosylformimino-AICAR-PH2O2-oxoglutarateoxidized thioredoxinH2OH2OUDPNADdihydroorotateH2Ohistidinal5-phosphoribosyl-n-formylglycineamidineorotidine-5’-phosphateacceptorphosphoribosyl-AMP5-phospho-ribosyl-glycineamideH2OfumerateH2OorotateD-erythro-imidazole-glycerol-phosphateimidazole acetol-phosphateoxidized flavodoxinCTPreduced acceptorphosphoribosylformiminoAICAR-phosphateAMPH2Oreduced flavodoxinNADUTPHIS4HIS6ATPADPADPADE16dGDPNADHATPL-glutamate2 ADPADPHIS42 ATPURA3ADE5,7URA10PRPPphosphateGMPATPURA8ATPADE17NADHURA6ADPpyrophosphateNADHphosphateRNR1URA2L-glutamateADE2pyrophosphateADPADE13PRS1ADPphosphateIMD4HIS5ATPRNR3PRS2ADE8GUK1phosphateL-histidinol-phosphate10-formyl-THF10-formyl-THFADPRNR4ADE17GDPADPURA2ATPURA4phosphateL-glutamineADPHIS4HIS1ADE16L-glutamineATPCDPATPL-glutamateL-glutamatephosphatephosphateL-glycineL-glutamineADE5,7L-glutamineL-glutaminephosphateAICARATPpyrophosphateL-glutamateURA7ADE4GTPD-ribose-5-phosphateURA1L-glutamateATPYNK1URA5HIS3GUA1ATPADE1YNK1ATPATPADPphosphateIMD2PRS4HIS4HIS2ADPADPPRS3pyrophosphatexanthosine-5-phosphateL-glutamateATPL-glutamineIMD3ATPRNR2L-histidinephosphatePRS5ADE6pyrophosphateATP


Description

No description

Comments

GenMAPP remarks 
Based on http://pathway.yeastgenome.org/biocyc/

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Quality Tags

Ontology Terms

 

Bibliography

  1. ''Histidine, purine, and pyrimidine superpathway''; YeastPathways,

History

View all...
CompareRevisionActionTimeUserComment
135448view21:58, 5 September 2024KhanspersOntology Term : 'classic metabolic pathway' added !
135447view21:58, 5 September 2024Khanspersremoved GenMAPP comments
135446view21:57, 5 September 2024Khanspers
135445view21:56, 5 September 2024Khansperslit ref
135314view00:05, 17 August 2024Khanspersinteractions
122754view05:17, 10 May 2022EgonwAdded identifiers to water nodes
117345view11:53, 20 May 2021EweitzModified title
107259view14:35, 17 September 2019MaintBotChEBI identifier normalization
94664view13:18, 4 October 2017DeSlChanged ribose-5-P label to D-ribose-5-P
94663view13:17, 4 October 2017DeSlConnected all lines, changed all textlabels to metabolite nodes, connected all genes to the lines.
93079view09:22, 28 July 2017ElisaFixed some of the unconnected interactions (left side of the pathway).
93011view14:46, 24 July 2017DeSlChanged wrong CAS number (salt) for correct ChEBI ID
85638view16:11, 4 June 2016EgonwFixed the CAS number.
71897view10:35, 22 October 2013Mkutmonchanged AICAR from Unknown to Metabolite
70270view21:50, 15 July 2013MaintBotupdated to 2013 schema
69872view18:00, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
67670view11:47, 26 June 2013DdiglesOntology Term : 'nucleotide metabolic pathway' added !
41803view04:48, 2 March 2011MaintBotRemoved redundant pathway information and comments
21558view11:32, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Superpathway of Histidine Purine and Pyrimidine Biosynthesis]] moved to [[Pathway:WP416]]: Moved to stable identifier
12861view08:06, 17 May 2008MaintBotautomated metabolite conversion
8948view14:13, 7 January 2008MaintBotAdded to category $category
8946view14:13, 7 January 2008M.BraymerUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
10-formyl-THFMetabolite2800-34-2 (CAS)
2 ADPMetabolite58-64-0 (CAS)
2 ATPMetabolite1927-31-7 (CAS)
2-oxoglutarateMetabolite
5-phospho-ribosyl-glycineamideMetabolite
5-phosphoribosyl-n-formylglycineamidineMetabolite
5-phosphoribosylamineMetabolite
5’-phosphoribosyl-4-(N-Metabolite
5’-phosphoribosyl-5-aminoimidazoleMetabolite
5’-phosphoribosyl-N-formylglycineamideMetabolite
ADE13GeneProductS000004351 (SGD)
ADE16GeneProductS000004018 (SGD)
ADE17GeneProductS000004727 (SGD)
ADE1GeneProductS000000070 (SGD)
ADE2GeneProductS000005654 (SGD)
ADE4GeneProductS000004915 (SGD)
ADE5,7GeneProductS000003203 (SGD)
ADE6GeneProductS000003293 (SGD)
ADE8GeneProductS000002816 (SGD)
ADPMetabolite58-64-0 (CAS)
AICARMetabolite3031-94-5 (CAS)
AMPMetabolite
ATPMetabolite1927-31-7 (CAS)
CDPMetabolite63-38-7 (CAS)
CO2Metabolite
CTPMetabolite
D-erythro-imidazole-glycerol-phosphateMetabolite
D-ribose-5-phosphateMetabolite3615-55-2 (CAS)
GDPMetabolite146-91-8 (CAS)
GMPMetabolite85-32-5 (CAS)
GTPMetabolite2564-35-4 (CAS)
GUA1GeneProductS000004830 (SGD)
GUK1GeneProductS000001550 (SGD)
H+Metabolite
H2OMetaboliteCHEBI:15377 (ChEBI)
HCO3Metabolite
HIS1GeneProductS000000857 (SGD)
HIS2GeneProductS000001921 (SGD)
HIS3GeneProductS000005728 (SGD)
HIS4GeneProductS000000535 (SGD)
HIS5GeneProductS000001378 (SGD)
HIS6GeneProductS000001282 (SGD)
IMD2GeneProductS000001259 (SGD)
IMD3GeneProductS000004424 (SGD)
IMD4GeneProductS000004520 (SGD)
IMPMetabolite
L-aspartateMetabolite
L-glutamateMetabolite56-86-0 (CAS)
L-glutamineMetabolite56-85-9 (CAS)
L-glycineMetabolite56-40-6 (CAS)
L-histidineMetabolite71-00-1 (CAS)
L-histidinol-phosphateMetabolite25679-93-0 (CAS)
NADMetabolite
NADHMetabolite53-84-9 (CAS)
NH3Metabolite
PRPPMetabolite97-55-2 (CAS)
PRS1GeneProductS000001664 (SGD)
PRS2GeneProductS000000901 (SGD)
PRS3GeneProductS000001003 (SGD)
PRS4GeneProductS000000164 (SGD)
PRS5GeneProductS000005422 (SGD)
RNR1GeneProductS000000872 (SGD)
RNR2GeneProductS000003563 (SGD)
RNR3GeneProductS000001328 (SGD)
RNR4GeneProductS000003412 (SGD)
THFMetabolite
UDPMetabolite
UMPMetabolite
URA10GeneProductS000004884 (SGD)
URA1GeneProductS000001699 (SGD)
URA2GeneProductS000003666 (SGD)
URA3GeneProductS000000747 (SGD)
URA4GeneProductS000004412 (SGD)
URA5GeneProductS000004574 (SGD)
URA6GeneProductS000001507 (SGD)
URA7GeneProductS000000135 (SGD)
URA8GeneProductS000003864 (SGD)
UTPMetabolite
YNK1GeneProductS000001550 (SGD)
carbamoyl-L-aspartateMetabolite
carbamoyl-phosphateMetabolite
dGDPMetaboliteCHEBI:28862 (ChEBI)
deoxy-GTPMetabolite
dihydroorotateMetabolite
fumerateMetabolite
histidinalMetabolite
histidinolMetabolite
imidazole acetol-phosphateMetabolite
orotateMetabolite
orotidine-5’-phosphateMetabolite
oxidized flavodoxinMetabolite
oxidized thioredoxinMetaboliteCHEBI:15377 (ChEBI)
phosphateMetabolite14265-44-2 (CAS)
phosphoribosyl-AMPMetabolite
phosphoribosyl-ATPMetabolite
phosphoribosyl-carboxy-aminoimidazoleMetabolite
phosphoribosyl-formamido-carboxamideMetabolite
phosphoribosylformiminoAICAR-phosphateMetabolite
phosphoribulosylformimino-AICAR-PMetabolite
pyrophosphateMetabolite2466-09-3 (CAS)
reduced flavodoxinMetabolite
reduced thioredoxinMetabolite
sucinocarboxamide)-5-aminoimidazoleMetabolite
xanthosine-5-phosphateMetabolite523-98-8 (CAS)

Annotated Interactions

No annotated interactions
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