SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome (Homo sapiens)

From WikiPathways

Revision as of 13:49, 26 March 2024 by Mkutmon (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none StimulationLegendSMC3SMC1A/SMC3 Role in DNA Damage RepairDSBRAD21SMC1ASMC3BRCA1NBNMRE11RAD50IRBRCA1RAD21SMC1ASMC3RAD21SMC1ASMC3NBNMRE11RAD50ATMATMATMBRCA1NBNMRE11RAD50RAD21SMC1ASMC3RAD21SMC1ASMC3ATMATMSMC1ASMC1ABRCA1NBNATMATMATMPAXIP1RAD18MDC1MDC1PAXIP1S Phase ArrestRAD18InhibitionChromatidRecruitmentIRIonizing RadiationDSBDouble Strand BreakSMC3ATMName: SMC1/SMC3 role in DNA damage - Cornelia de Lange SyndromeOrganism: Homo sapiens


Description

Role of cohesin subunits SMC1 and SMC3 during DNA damage response.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Image:Unconnected.pngFix interactions
Image:Curated.pngApproved version

Ontology Terms

Bibliography

  1. Yi F, Wang Z, Liu J, Zhang Y, Xu H, Li X, Bai N, Cao L, Song X; ''Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis.''; Int J Biol Sci, 2017 PubMed Europe PMC Scholia
  2. Litwin I, Pilarczyk E, Wysocki R; ''The Emerging Role of Cohesin in the DNA Damage Response.''; Genes (Basel), 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
129308
Approved
view13:49, 26 March 2024MkutmonOntology Term : 'disease pathway' added !
125319view21:50, 31 January 2023LarsgwFix reference bp:ID
119397view10:49, 27 June 2021EweitzOntology Term : 'Cornelia de Lange syndrome' added !
119396view10:49, 27 June 2021EweitzModified title
119108view12:37, 17 June 2021IrkilmezANew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ATMGeneProductENSG00000149311 (Ensembl) While SMC1A is specifically phosphorylated by phosphorylated ATM, no information was found on if the same applies to SMC3.
BRCA1GeneProductENSG00000012048 (Ensembl)
MDC1GeneProductENSG00000137337 (Ensembl)
MRE11GeneProductENSG00000020922 (Ensembl)
NBNGeneProductENSG00000104320 (Ensembl)
PAXIP1GeneProductENSG00000157212 (Ensembl)
RAD18GeneProductENSG00000070950 (Ensembl)
RAD21GeneProductENSG00000164754 (Ensembl)
RAD50GeneProductENSG00000113522 (Ensembl)
SMC1AGeneProductENSG00000072501 (Ensembl)
SMC3GeneProductENSG00000108055 (Ensembl)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5118"
Personal tools