ALA oxylipin metabolism (Homo sapiens)
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Description
Alpha-linolenic acid (ALA) oxylipin metabolism by ALOX5, ALOX15, and cytochrome P450
Quality Tags
Ontology Terms
Bibliography
- Galliard T, Phillips DR; ''Lipoxygenase from potato tubers. Partial purification and properties of an enzyme that specifically oxygenates the 9-position of linoleic acid.''; Biochem J, 1971 PubMed Europe PMC Scholia
- Gabbs M, Leng S, Devassy JG, Monirujjaman M, Aukema HM; ''Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs.''; Adv Nutr, 2015 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
12(13)-EpODE | Metabolite | 16061061 (PubChem-compound) ![]() | |
12,13-DiHODE | Metabolite | HMDB10201 (HMDB) ![]() | |
13-HOTrE | Metabolite | 10469728 (PubChem-compound) ![]() | |
13-HpOTrE | Metabolite | CHEBI:145300 (ChEBI) ![]() | |
13-OxoOTrE | Metabolite | ||
15(16)-EpODE | Metabolite | HMDB10206 (HMDB) ![]() | |
15,16-DiHODE | Metabolite | HMDB10208 (HMDB) ![]() | |
9(10)-EpODE | Metabolite | HMDB10220 (HMDB) ![]() | |
9(S)-HpOTrE | Metabolite | CHEBI:60961 (ChEBI) ![]() | |
9,10-DiHODE | Metabolite | HMDB10221 (HMDB) ![]() | |
9,16-DiHOTrE | Metabolite | ||
9-HOTrE | Metabolite | 10447175 (PubChem-compound) ![]() | |
9-OxoOTrE | Metabolite | 125559-74-2 (CAS) ![]() | |
ALOX15 | GeneProduct | ENSG00000161905 (Ensembl) ![]() | |
ALOX5 | GeneProduct | ENSG00000012779 (Ensembl) ![]() | |
cytochrome P450 | Metabolite | CHEBI:38559 (ChEBI) ![]() | |
sEH | GeneProduct | ENSG00000120915 (Ensembl) ![]() | |
α-Linolenic acid | Metabolite | 27432 (ChEBI) ![]() |
Annotated Interactions
No annotated interactions