Lung pathology of COVID-19 (Homo sapiens)
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Revision as of 22:10, 30 January 2024 by
Eweitz
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Airway epithelial cell
Cell death
SARS-CoV-2
Nucleus
Increased in serum and
bronchoalveolar lavage fluid
TLR3
DDX58
IRF3
CXCL9
CCL2
CSF2
IL18
STING1
IL6
TLR8
TLR7
TBK1
CXCL10
CGAS
MAVS
IL1B
TNF
IFIH1
NFKB1
IFN-I
IFN-II
CXCL8
CXCL11
IRF3
NFKB1
1
Description
Beginning of a pathway on the Lung Pathology of COVID-19 based on a figure in a paper (Reference 1)
Comments
This pathway is based on figure 4 of Ref 1
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Bibliography
Harrison AG, Lin T, Wang P; ''Mechanisms of SARS-CoV-2 Transmission and Pathogenesis.''; Trends Immunol, 2020
PubMed
Europe PMC
Scholia
History
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Revision
Action
Time
User
Comment
128308
view
22:10, 30 January 2024
Eweitz
Ontology Term : 'epithelial cell' added !
128307
view
14:39, 30 January 2024
Mkutmon
changed text to labels
120619
view
23:32, 18 December 2021
Eweitz
Label group of genes
120618
view
17:59, 18 December 2021
Eweitz
Remove "Golgi" label due to WP-PathVisio graphics issue
120617
view
17:57, 18 December 2021
Eweitz
Fix WP-PathVisio graphics issue; label organelles, virus
120616
view
13:08, 18 December 2021
Eweitz
Use official gene symbol, STING1
120615
view
13:04, 18 December 2021
Eweitz
Tighten graphics, refine datanodes, case
120379
view
23:48, 29 November 2021
Eweitz
Ontology Term : 'COVID-19' added !
120378
view
23:47, 29 November 2021
Eweitz
Modified title
120328
view
16:04, 26 November 2021
XNauts
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CCL2
GeneProduct
ENSG00000108691 (Ensembl)
CGAS
GeneProduct
ENSG00000164430 (Ensembl)
CSF2
GeneProduct
ENSG00000164400 (Ensembl)
CXCL10
GeneProduct
ENSG00000169245 (Ensembl)
CXCL11
GeneProduct
ENSG00000169248 (Ensembl)
CXCL8
Metabolite
CHEBI:138181 (ChEBI)
CXCL9
GeneProduct
ENSG00000138755 (Ensembl)
DDX58
GeneProduct
ENSG00000107201 (Ensembl)
IFIH1
GeneProduct
ENSG00000115267 (Ensembl)
IFN-II
PF00714 (Pfam)
IFN-I
PF00143 (Pfam)
IL18
GeneProduct
ENSG00000150782 (Ensembl)
IL1B
GeneProduct
ENSG00000125538 (Ensembl)
IL6
GeneProduct
ENSG00000136244 (Ensembl)
IRF3
GeneProduct
ENSG00000126456 (Ensembl)
MAVS
GeneProduct
ENSG00000088888 (Ensembl)
NFKB1
GeneProduct
ENSG00000109320 (Ensembl)
STING1
GeneProduct
ENSG00000184584 (Ensembl)
TBK1
GeneProduct
ENSG00000183735 (Ensembl)
TLR3
GeneProduct
ENSG00000164342 (Ensembl)
TLR7
GeneProduct
ENSG00000196664 (Ensembl)
TLR8
GeneProduct
ENSG00000101916 (Ensembl)
TNF
GeneProduct
ENSG00000232810 (Ensembl)
Annotated Interactions
No annotated interactions
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View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions