Glycosylphosphatidyl inositol anchor pathway (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none ER LumenMetabolitePIGVflippaseMPPE1PGAP1PGAP2PGAP3MetaboliteMetaboliteMetabolitePIGNPIGBMetaboliteMetaboliteMetabolitePIGFPIGOPIGFPIGGGPAA1PIGKPIGTPIGSPIGUEndoplasmicReticulumMembraneGolgi then Cell SurfaceCytoplasmMetaboliteMetaboliteMetaboliteMetaboliteMetabolitePIGMPIGXPIGWDPM2PIGAPIGHPIGCPIGQPIGPPIGYPIGLMetaboliteName: Glycosylphosphatidyl inositol anchor pathwayOrganism: Homo sapiens


Description

Literature reference

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Quality Tags

Ontology Terms

Bibliography

  1. Lam C, Golas GA, Davids M, Huizing M, Kane MS, Krasnewich DM, Malicdan MCV, Adams DR, Markello TC, Zein WM, Gropman AL, Lodish MB, Stratakis CA, Maric I, Rosenzweig SD, Baker EH, Ferreira CR, Danylchuk NR, Kahler S, Garnica AD, Bradley Schaefer G, Boerkoel CF, Gahl WA, Wolfe LA; ''Expanding the clinical and molecular characteristics of PIGT-CDG, a disorder of glycosylphosphatidylinositol anchors.''; Mol Genet Metab, 2015 PubMed Europe PMC Scholia
  2. Freeze HH; ''Understanding human glycosylation disorders: biochemistry leads the charge.''; J Biol Chem, 2013 PubMed Europe PMC Scholia
  3. Komath SS, Fujita M, Hart GW, Ferguson MAJ, Kinoshita T; ''Glycosylphosphatidylinositol Anchors.''; , 2022 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
136116view12:09, 19 December 2024Mkutmonlayout
136115view11:15, 19 December 2024Mkutmonuniprot ids + layout
136106view08:08, 19 December 2024EgonwThe Freeze 2013 paper relies on this book chapter (ed. 2, this is ed 4.)
136105view06:59, 19 December 2024EgonwOther another relevant paper
136101view15:20, 18 December 2024EgonwFixed the label
136100view12:36, 18 December 2024EgonwOntology Term : 'glycosylphosphatidylinositol anchor biosynthetic pathway' added !
136099view12:36, 18 December 2024EgonwOntology Term : 'classic metabolic pathway' added !
136097view07:30, 18 December 2024EgonwA translocation (kind of)
136096view21:43, 17 December 2024EgonwAll genes added now
136095view21:18, 17 December 2024EgonwMore genes
136094view21:00, 17 December 2024EgonwAdded first three PIG* genes
136093view20:45, 17 December 2024EgonwNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
DPM2ProteinO94777 (Uniprot-TrEMBL)
GPAA1ProteinO43292 (Uniprot-TrEMBL)
MPPE1ProteinQ53F39 (Uniprot-TrEMBL) old name: PGAP5
MetaboliteMetabolite
PGAP1ProteinQ75T13 (Uniprot-TrEMBL)
PGAP2ProteinQ9UHJ9 (Uniprot-TrEMBL)
PGAP3ProteinQ96FM1 (Uniprot-TrEMBL)
PIGAProteinP37287 (Uniprot-TrEMBL)
PIGBProteinQ92521 (Uniprot-TrEMBL)
PIGCProteinQ92535 (Uniprot-TrEMBL)
PIGFProteinQ07326 (Uniprot-TrEMBL)
PIGGProteinQ5H8A4 (Uniprot-TrEMBL)
PIGHProteinQ14442 (Uniprot-TrEMBL)
PIGKProteinQ92643 (Uniprot-TrEMBL)
PIGLProteinQ9Y2B2 (Uniprot-TrEMBL)
PIGMProteinQ9H3S5 (Uniprot-TrEMBL)
PIGNProteinO95427 (Uniprot-TrEMBL)
PIGOProteinQ8TEQ8 (Uniprot-TrEMBL)
PIGPProteinP57054 (Uniprot-TrEMBL)
PIGQProteinQ9BRB3 (Uniprot-TrEMBL)
PIGSProteinQ96S52 (Uniprot-TrEMBL)
PIGTProteinQ969N2 (Uniprot-TrEMBL)
PIGUProteinQ9H490 (Uniprot-TrEMBL)
PIGVProteinQ9NUD9 (Uniprot-TrEMBL)
PIGWProteinQ7Z7B1 (Uniprot-TrEMBL)
PIGXProteinQ8TBF5 (Uniprot-TrEMBL)
PIGYProteinQ3MUY2 (Uniprot-TrEMBL)
flippaseGeneProduct

Annotated Interactions

No annotated interactions

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