Insulin signaling (Mus musculus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Tor signalingGlucose transportTranscriptional regulators & immediate early genesFoxo1Elk1FosJunSrfFoxo3aEgr1p90 Rsk kinasesRps6ka1Rps6ka3Rps6ka5Rps6ka2Rps6ka6Rps6ka4Insulin receptor substratesIrs3Shc3Irs4Gab1Irs2Irs1Shc1Shc2MEK/MAP kinasesMapk10Map3k5Map3k3Mapk8Map4k2Map2k2Mink1Map3k2Mapk9Map2k3Map3k14Mapk4Mapk13Map2k5Mapk11Mapk6Mapk3Map4k4Map4k5Mapk7Map3k4Map3k7Map2k6Mapk1Map3k1Map3k10Map2k7Mapk12Map3k6Map2k1Map3k13Map4k3Map3k9Map3k12Map2k4Map3k8Map3k11Mapk14Map4k1Metabolic regulationPfkmLipeGys1Gys2Ppp1ccPfklGyg1Vesicular traffickingTbc1d4Kif3aFlot2Stxbp4Stxbp1Stxbp2CblEhd1RhoqStxbp3Arf6MGI:1345171Flot1Pscd3Kif5bMyo1cRapgef1CblcStx4aSnap25CblbArf1Snx26Vamp2CrkRab4aEhd2RhojCap1Snap23Sorbs1p70 S6 kinasesRps6kb1Rps6kb2Modulators of insulin actionPtpn1Socs3PtprfXbp1PtenPrkcdPrkcb1PrkchPrkaa2Inppl1PrkcqSocs1Inpp4aIkbkbMapk8PrkciPtpn11PrkczPrkcaPrkaa1Trib3Enpp1PI 3-kinasePik3r3Pik3r2Pik3c2aPik3cdPik3r1Pik3r4Pik3c3Pik3cgPik3caPik3c2gPik3cbPDK/Akt signalingAkt2Gsk3bSgk3Sgk2Gsk3aPdpk1Akt1Sgk1Translation regulationEif4eEif4ebp1Ras-MAPK signalingRac2Hras1Raf1Sos1Grb14Rac1Grb2Grb10RradSos2Frap1RhebTsc2Tsc1Igf1rInsrSlc2a1Slc2a4Name: Insulin signalingLast Modified: 10/17/2013Organism: Mus musculus


Description

No description

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Quality Tags

Image:MissingDescription.pngAdd description
Image:NeedsRef.pngAdd references
Image:Curated.pngApproved version

Ontology Terms

Pathway Ontology : insulin signaling pathway
 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
128033
Approved
view17:14, 21 January 2024EweitzStandardize case
116717view09:58, 11 May 2021EweitzModified title
88446view14:27, 8 August 2016Mkutmonadded missing annotation
82885view12:43, 11 November 2015JmeliusCorrect outdated id
78424view10:26, 7 January 2015MaintBotadded missing graphIds
71726view20:16, 17 October 2013MaintBotAutomated update of data sources
69101view18:12, 8 July 2013MaintBotUpdated to 2013 gpml schema
67395view10:55, 26 June 2013DdiglesOntology Term : 'insulin signaling pathway' added !
57331view18:59, 25 January 2013MkutmonReverted to version '17:15, 25 January 2013' by Mkutmon
57324view17:16, 25 January 2013MkutmonReverted to version '00:22, 2 March 2011' by Mkutmon
57323view17:15, 25 January 2013Mkutmonfixed unconnected lines
41286view00:22, 2 March 2011MaintBotRemoved redundant pathway information and comments
33395view14:46, 30 November 2009MaintBotRemoved group label
32969view23:23, 28 September 2009MaintBotAdded connectors
29169view12:25, 9 April 2009EveloPeriodical save, work in progress
29164view09:18, 9 April 2009EveloMainly cosmetic
28129view19:41, 27 January 2009KhanspersChanged name
20815view11:30, 14 November 2008MaintBot[[Pathway:Mus musculus:Insulin Signaling]] moved to [[Pathway:WP65]]: Moved to stable identifier
8214view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Insulin Signaling]] moved to [[Pathway:Mus musculus:Insulin Signaling]]: Renaming species
7727view16:13, 18 December 2007MaintBotfixed category names
7266view12:41, 4 November 2007MaintBotAdded categories to GPML
6468view22:19, 22 May 2007M.Pattigpml file for [[Mouse:Insulin_Signaling]]

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
Akt1GeneProduct11651 (Entrez Gene)
Akt2GeneProduct11652 (Entrez Gene)
Arf1GeneProduct11840 (Entrez Gene)
Arf6GeneProduct11845 (Entrez Gene)
Cap1GeneProduct12331 (Entrez Gene)
CblGeneProduct12402 (Entrez Gene)
CblbGeneProduct208650 (Entrez Gene)
CblcGeneProduct80794 (Entrez Gene)
CrkGeneProduct12928 (Entrez Gene)
Egr1GeneProduct13653 (Entrez Gene)
Ehd1GeneProduct13660 (Entrez Gene)
Ehd2GeneProduct259300 (Entrez Gene)
Eif4eGeneProduct13684 (Entrez Gene)
Eif4ebp1GeneProduct13685 (Entrez Gene)
Elk1GeneProduct13712 (Entrez Gene)
Enpp1GeneProduct18605 (Entrez Gene)
Flot1GeneProduct14251 (Entrez Gene)
Flot2GeneProduct14252 (Entrez Gene)
FosGeneProduct14281 (Entrez Gene)
Foxo1GeneProduct56458 (Entrez Gene)
Foxo3aGeneProduct56484 (Entrez Gene)
Frap1GeneProduct56717 (Entrez Gene)
Gab1GeneProduct14388 (Entrez Gene)
Grb10GeneProduct14783 (Entrez Gene)
Grb14GeneProduct50915 (Entrez Gene)
Grb2GeneProduct14784 (Entrez Gene)
Gsk3aGeneProduct245619 (Entrez Gene)
Gsk3bGeneProduct56637 (Entrez Gene)
Gyg1GeneProduct27357 (Entrez Gene)
Gys1GeneProduct14936 (Entrez Gene)
Gys2GeneProduct232493 (Entrez Gene)
Hras1GeneProduct15461 (Entrez Gene)
Igf1rGeneProduct16001 (Entrez Gene)
IkbkbGeneProduct16150 (Entrez Gene)
Inpp4aGeneProduct269180 (Entrez Gene)
Inppl1GeneProduct16332 (Entrez Gene)
InsrGeneProduct16337 (Entrez Gene)
Irs1GeneProduct16367 (Entrez Gene)
Irs2GeneProduct16368 (Entrez Gene)
Irs3GeneProduct16369 (Entrez Gene)
Irs4GeneProduct16370 (Entrez Gene)
JunGeneProduct16476 (Entrez Gene)
Kif3aGeneProduct16568 (Entrez Gene)
Kif5bGeneProduct16573 (Entrez Gene)
LipeGeneProduct16890 (Entrez Gene)
MGI:1345171GeneProduct23921 (Entrez Gene)
Map2k1GeneProduct26395 (Entrez Gene)
Map2k2GeneProduct26396 (Entrez Gene)
Map2k3GeneProduct26397 (Entrez Gene)
Map2k4GeneProduct26398 (Entrez Gene)
Map2k5GeneProduct23938 (Entrez Gene)
Map2k6GeneProduct26399 (Entrez Gene)
Map2k7GeneProduct26400 (Entrez Gene)
Map3k10GeneProductENSMUSG00000040390 (Ensembl)
Map3k11GeneProduct26403 (Entrez Gene)
Map3k12GeneProduct26404 (Entrez Gene)
Map3k1GeneProduct26401 (Entrez Gene)
Map3k13GeneProduct71751 (Entrez Gene)
Map3k14GeneProduct53859 (Entrez Gene)
Map3k2GeneProduct26405 (Entrez Gene)
Map3k3GeneProduct26406 (Entrez Gene)
Map3k4GeneProduct26407 (Entrez Gene)
Map3k5GeneProduct26408 (Entrez Gene)
Map3k6GeneProduct53608 (Entrez Gene)
Map3k7GeneProduct26409 (Entrez Gene)
Map3k8GeneProduct26410 (Entrez Gene)
Map3k9GeneProduct338372 (Entrez Gene)
Map4k1GeneProduct26411 (Entrez Gene)
Map4k2GeneProduct26412 (Entrez Gene)
Map4k3GeneProduct225028 (Entrez Gene)
Map4k4GeneProduct26921 (Entrez Gene)
Map4k5GeneProduct399510 (Entrez Gene)
Mapk10GeneProduct26414 (Entrez Gene)
Mapk11GeneProduct19094 (Entrez Gene)
Mapk12GeneProduct29857 (Entrez Gene)
Mapk1GeneProduct26413 (Entrez Gene)
Mapk13GeneProduct26415 (Entrez Gene)
Mapk14GeneProduct26416 (Entrez Gene)
Mapk3GeneProduct26417 (Entrez Gene)
Mapk4GeneProduct225724 (Entrez Gene)
Mapk6GeneProduct50772 (Entrez Gene)
Mapk7GeneProduct23939 (Entrez Gene)
Mapk8GeneProduct26419 (Entrez Gene)
Mapk9GeneProduct26420 (Entrez Gene)
Mink1GeneProduct50932 (Entrez Gene)
Myo1cGeneProduct17913 (Entrez Gene)
Pdpk1GeneProduct18607 (Entrez Gene)
PfklGeneProduct18641 (Entrez Gene)
PfkmGeneProduct18642 (Entrez Gene)
Pik3c2aGeneProduct18704 (Entrez Gene)
Pik3c2gGeneProduct18705 (Entrez Gene)
Pik3c3GeneProduct225326 (Entrez Gene)
Pik3caGeneProduct18706 (Entrez Gene)
Pik3cbGeneProduct74769 (Entrez Gene)
Pik3cdGeneProduct18707 (Entrez Gene)
Pik3cgGeneProduct30955 (Entrez Gene)
Pik3r1GeneProduct18708 (Entrez Gene)
Pik3r2GeneProduct18709 (Entrez Gene)
Pik3r3GeneProduct18710 (Entrez Gene)
Pik3r4GeneProduct75669 (Entrez Gene)
Ppp1ccGeneProduct19047 (Entrez Gene)
Prkaa1GeneProduct105787 (Entrez Gene)
Prkaa2GeneProduct108079 (Entrez Gene)
PrkcaGeneProduct18750 (Entrez Gene)
Prkcb1GeneProduct18751 (Entrez Gene)
PrkcdGeneProduct18753 (Entrez Gene)
PrkchGeneProduct18755 (Entrez Gene)
PrkciGeneProduct18759 (Entrez Gene)
PrkcqGeneProduct18761 (Entrez Gene)
PrkczGeneProduct18762 (Entrez Gene)
Pscd3GeneProduct19159 (Entrez Gene)
PtenGeneProduct19211 (Entrez Gene)
Ptpn11GeneProduct19247 (Entrez Gene)
Ptpn1GeneProduct19246 (Entrez Gene)
PtprfGeneProduct19268 (Entrez Gene)
Rab4aGeneProduct19341 (Entrez Gene)
Rac1GeneProduct19353 (Entrez Gene)
Rac2GeneProduct19354 (Entrez Gene)
Raf1GeneProduct110157 (Entrez Gene)
Rapgef1GeneProduct107746 (Entrez Gene)
RhebGeneProduct19744 (Entrez Gene)
RhojGeneProduct80837 (Entrez Gene)
RhoqGeneProduct104215 (Entrez Gene)
Rps6ka1GeneProduct20111 (Entrez Gene)
Rps6ka2GeneProduct20112 (Entrez Gene)
Rps6ka3GeneProduct110651 (Entrez Gene)
Rps6ka4GeneProduct56613 (Entrez Gene)
Rps6ka5GeneProduct73086 (Entrez Gene)
Rps6ka6GeneProduct67071 (Entrez Gene)
Rps6kb1GeneProduct72508 (Entrez Gene)
Rps6kb2GeneProduct58988 (Entrez Gene)
RradGeneProduct56437 (Entrez Gene)
Sgk1GeneProduct20393 (Entrez Gene)
Sgk2GeneProduct27219 (Entrez Gene)
Sgk3GeneProduct170755 (Entrez Gene)
Shc1GeneProduct20416 (Entrez Gene)
Shc2GeneProduct216148 (Entrez Gene)
Shc3GeneProduct20418 (Entrez Gene)
Slc2a1GeneProduct20525 (Entrez Gene)
Slc2a4GeneProduct20528 (Entrez Gene)
Snap23GeneProduct20619 (Entrez Gene)
Snap25GeneProduct20614 (Entrez Gene)
Snx26GeneProduct233071 (Entrez Gene)
Socs1GeneProduct12703 (Entrez Gene)
Socs3GeneProduct12702 (Entrez Gene)
Sorbs1GeneProduct20411 (Entrez Gene)
Sos1GeneProduct20662 (Entrez Gene)
Sos2GeneProduct20663 (Entrez Gene)
SrfGeneProduct20807 (Entrez Gene)
Stx4aGeneProduct20909 (Entrez Gene)
Stxbp1GeneProduct20910 (Entrez Gene)
Stxbp2GeneProduct20911 (Entrez Gene)
Stxbp3GeneProduct20912 (Entrez Gene)
Stxbp4GeneProduct20913 (Entrez Gene)
Tbc1d4GeneProduct210789 (Entrez Gene)
Trib3GeneProduct228775 (Entrez Gene)
Tsc1GeneProduct64930 (Entrez Gene)
Tsc2GeneProduct22084 (Entrez Gene)
Vamp2GeneProduct22318 (Entrez Gene)
Xbp1GeneProduct22433 (Entrez Gene)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP65"
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