Steroid biosynthesis (Rattus norvegicus)

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**To Mineralcorticoid Synthesis**To Glucocorticoid Synthesis**Hsd3b1TestosteroneAndrostenedioneHsd3b1Hydroxyprogesterone aldolaseHsd3b6Hsd3b1Hsd3b1Hsd3b1Hsd17b4Hsd17b2Hsd3b1Cholesterol* 3-beta-OH-delta-steroid DH & Steroid isomerase =Hsd3b1Hsd3bHsd3b1Hsd3b1Hydroxyprogesterone aldolase17-alpha-OH-ProgesteroneHsd3b5PregnenoloneF13b17-alpha-OH-PregnenoloneDihydrotestosteroneHsd3b6Hsd3b1Steroid-19-Hydroxylase** Estradiol-17-beta DH = DHBHsd3b6ProgesteroneEstroneEstradiolCyp17a1Steroid-19-HydroxylaseCyp17a1Hsd3b6Hsd3b1Hsd17b7Hsd3b1Hsd3bHsd3b5Hsd17b1Hsd17b3DHAHsd3bAndrostenediolHsd3bHsd3b6Hsd3b5Hsd3b5


Description

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Comments

GenMAPP notes 
MAPP converted from mouse to rat by NASA ARS/UMDNJ

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
117016view11:33, 16 May 2021EweitzModified title
107004view13:46, 17 September 2019MaintBotHMDB identifier normalization
93689view14:40, 9 August 2017DeSlAdded EC number for Hydroxyprogesterone aldolase, changed appearance of metabolite nodes.
78813view12:32, 31 January 2015EgonwFixed the Entrez ID for Hsd3b1 which is 360348 and not 29632 (which is Hsd3b6).
78812view12:30, 31 January 2015EgonwFixed the Entrez ID for Hsd3b6.
78803view19:10, 30 January 2015EgonwAdded the Entrez gene ID for Hsd3b5 (24470).
78802view19:07, 30 January 2015EgonwCopied metabolite identifiers from Hs,
78801view18:59, 30 January 2015EgonwConnected dots.
69437view19:04, 8 July 2013MaintBotUpdated to 2013 gpml schema
67662view11:46, 26 June 2013DdiglesOntology Term : 'steroid hormone biosynthetic pathway' added !
53714view19:12, 12 November 2012EgonwConnecting dots...
53703view13:12, 12 November 2012EgonwReplaced multiple general nodes by Metabolite DataNode's.
41761view02:41, 2 March 2011MaintBotRemoved redundant pathway information and comments
20817view11:30, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Steroid Biosynthesis]] moved to [[Pathway:WP66]]: Moved to stable identifier
8412view13:46, 7 January 2008MaintBot[[Pathway:Rat:Steroid Biosynthesis]] moved to [[Pathway:Rattus norvegicus:Steroid Biosynthesis]]: Renaming species
7823view16:20, 18 December 2007MaintBotfixed category names
7400view12:42, 4 November 2007MaintBotAdded categories to GPML
19546view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:Steroid_Biosynthesis]]
6597view22:20, 22 May 2007A.Kwagpml file for [[Rat:Steroid_Biosynthesis]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
* 3-beta-OH-delta-steroid DH & Steroid isomerase =Metabolite
** Estradiol-17-beta DH = DHBMetabolite
17-alpha-OH-PregnenoloneMetaboliteHMDB0000363 (HMDB)
17-alpha-OH-ProgesteroneMetaboliteHMDB0000374 (HMDB)
AndrostenediolMetaboliteHMDB0005849 (HMDB)
AndrostenedioneMetabolite63-05-8 (CAS)
CholesterolMetabolite57-88-5 (CAS)
Cyp17a1GeneProduct25146 (Entrez Gene)
DHAMetabolite53-43-0 (CAS)
DihydrotestosteroneMetaboliteHMDB0002961 (HMDB)
EstradiolMetabolite57-91-0 (CAS)
EstroneMetabolite53-16-7 (CAS)
F13bGeneProduct289055 (Entrez Gene)
Hsd17b1GeneProduct25322 (Entrez Gene)
Hsd17b2GeneProduct79243 (Entrez Gene)
Hsd17b3GeneProduct117182 (Entrez Gene)
Hsd17b4GeneProduct79244 (Entrez Gene)
Hsd17b7GeneProduct29540 (Entrez Gene)
Hsd3b1GeneProduct360348 (Entrez Gene)
Hsd3bGeneProduct24470 (Entrez Gene)
Hsd3b5GeneProduct24470 (Entrez Gene) Homologous to SwissProt ID: 3BH5 MOUSE
Hsd3b6GeneProduct29632 (Entrez Gene)
Hydroxyprogesterone aldolaseGeneProduct4.1.2.30 (Enzyme Nomenclature)
PregnenoloneMetabolite145-13-1 (CAS)
ProgesteroneMetabolite57-83-0 (CAS)
Steroid-19-HydroxylaseGeneProduct
TestosteroneMetabolite58-22-0 (CAS)

Annotated Interactions

No annotated interactions
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