NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde (Saccharomyces cerevisiae)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none spontaneousH+nicotinate adenine dinucleotide2-amino-3-carboxymuconate-6-semialdehydequinolinateL-tryptophan degradation to 2-amino-3-carboxymuconate semialdehydeH2OQNS1BNA6NAD+β-nicotinate D-ribonucleotidediphosphateL-glutamateAMPH+NMA2NMA1ATPH+L-glutamineATPH2OdiphosphateName: NAD biosynthesis from 2-amino-3-carboxymuconate semialdehydeOrganism: Saccharomyces cerevisiae


Description

This is the later portion of the pathway used in eukaryotes for de novo biosynthesis of NAD, which starts with the amino acid L-tryptophan. Description from https://pathway.yeastgenome.org/.

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Quality Tags

Image:Curated.pngApproved version

Ontology Terms

Pathway Ontology : Wnt signaling pathway
Cell Type : embryonic stem cell
 

Bibliography

  1. ''NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde''; YeastPathways,

History

View all...
CompareRevisionActionTimeUserComment
138076
Approved
view18:38, 13 March 2025KhanspersOntology Term : 'classic metabolic pathway' added !
138075view18:38, 13 March 2025KhanspersModified title
138074view18:37, 13 March 2025KhanspersModified description
138073view18:36, 13 March 2025Khanspersupdate reference and decrease board height
138072view18:35, 13 March 2025Khanspersupdate, added reference
138071view18:32, 13 March 2025Khanspersupdating
138070view18:16, 13 March 2025Khanspersupdating based on YeastPathways
117316view11:21, 20 May 2021EweitzModified title
71345view18:02, 17 October 2013MaintBotAutomated update of data sources
70051view05:59, 12 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69615view20:33, 8 July 2013MaintBotUpdated to 2013 gpml schema
67503view11:10, 26 June 2013DdiglesOntology Term : 'NAD biosynthetic pathway' added !
54304view13:51, 27 November 2012EgonwReplaced a Label with a DataNode.
41849view04:51, 2 March 2011MaintBotRemoved redundant pathway information and comments
20857view11:30, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:NAD Biosynthesis]] moved to [[Pathway:WP84]]: Moved to stable identifier
12786view08:02, 17 May 2008MaintBotautomated metabolite conversion
8837view14:10, 7 January 2008MaintBotAdded to category $category
8835view14:10, 7 January 2008M.BraymerUploaded new pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
2-amino-3-carboxymuconate-6-semialdehyde Metabolite994 (ChEBI)
AMPMetabolite456215 (ChEBI)
ATPMetabolite1927-31-7 (CAS)
BNA6GeneProductS000001943 (SGD)
H+Metabolite15378 (ChEBI)
H2OMetabolite15377 (ChEBI)
L-glutamateMetabolite56-86-0 (CAS)
L-glutamineMetabolite56-85-9 (CAS)
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehydePathway
NAD+Metabolite57540 (ChEBI)
NMA1GeneProductS000004320 (SGD)
NMA2GeneProductS000003242 (SGD)
QNS1GeneProductS000001116 (SGD)
diphosphateMetabolite2466-09-3 (CAS)
nicotinate adenine dinucleotideMetabolite58437 (ChEBI)
quinolinateMetaboliteHMDB00232 (HMDB)
β-nicotinate D-ribonucleotideMetabolite57502 (ChEBI)

Annotated Interactions

No annotated interactions

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