T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection (Homo sapiens)
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Description
This pathway is based on Figure 4 of "A Model of an Integrated Immune System Pathway in Homo sapiens and Its Interaction with Superantigen Producing Expression Regulatory Pathway in Staphylococcus aureus: Comparing Behavior of Pathogen Perturbed and Unperturbed Pathway"(see bibliography). The pathway displays the T-cell receptors of homo sapiens when infected with the disease Staphylococcus Enterotoxin B. The binding of a superantigen to the T cell receptor results in a protein signaling pathway resulting in cell proliferation, differentiation, and immune response due to altered DNA expression. SEB refers to Staphylococcal Enterotoxin B.
Quality Tags
Ontology Terms
Pathway Ontology : calcium/calmodulin dependent signaling pathway G protein mediated signaling pathway via Galphai family G protein mediated signaling pathway via Galphas family Ras superfamily mediated signaling pathway G protein mediated signaling pathway via Galphaq family endothelin signaling pathway
Disease : hypertension benign essential hypertension
Cell Type : smooth muscle cell blood vessel endothelial cell
Bibliography
- Tomar N, De RK; ''A model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathway.''; PLoS One, 2013 PubMed Europe PMC Scholia
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Annotated Interactions
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