Eicosanoid lipid synthesis map (Mus musculus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none GPPla2g5Pla2g6Pla2g4aPla2g4bAAPtgs1Ptgs2Ptgs1Ptgs2PGG2PGH2PGE2PtgesPGF2aPGD2PGJ215-deoxy-PGJ215-deoxy-PGD2Ptgds5-HETE11-HETEAlox5Name: Eicosanoid lipid synthesis mapOrganism: Mus musculus


Description

In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central nervous system. Source: [Wikipedia](https://en.wikipedia.org/wiki/Eicosanoid).

This pathway is inspired by the [Lipidmaps>Eicosanoids pathway](https://lipidmaps.org/resources/pathways/vanted.php).

For Homo sapiens, the information from this pathway has been integrated with the pre-existing pathway at [WikiPathways](https://www.wikipathways.org/index.php/Pathway:WP167).

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Quality Tags

Image:Curated.pngApproved version
Image:NeedsRef.pngAdd references

Ontology Terms

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
137672
Approved
view20:04, 6 March 2025KhanspersModified description
136932view19:37, 26 February 2025KhanspersModified description
117875view10:19, 23 May 2021EweitzModified title
110706view14:17, 28 May 2020EgonwAdded missing @Type annotation
98939view12:58, 16 October 2018DeSlConnected last unconnected line.
98471view05:42, 8 September 2018Egonw
98455view12:55, 7 September 2018DeSlNow really added last nodes + identifiers
98454view12:51, 7 September 2018DeSlOntology Term : 'eicosanoid biosynthetic pathway' added !
98453view12:50, 7 September 2018DeSlOntology Term : 'inflammatory response pathway' added !
98446view12:36, 7 September 2018DeSlModified description
98445view12:35, 7 September 2018DeSlModified description
98444view12:32, 7 September 2018DeSlAdded IDs for added nodes.
98443view12:29, 7 September 2018DeSlAdded last missing part of nodes
98442view06:12, 7 September 2018EgonwAdded identifiers, also for the mouse genes.
98441view05:43, 7 September 2018EgonwModified title
98418view13:03, 6 September 2018MaintBotModified description
98417view13:03, 6 September 2018MaintBotModified title
98416view12:45, 6 September 2018EgonwNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
11-HETEMetaboliteQ27140010 (Wikidata)
15-deoxy-PGD2Metabolite5283052 (PubChem-compound)
15-deoxy-PGJ2Metabolite5311211 (PubChem-compound)
5-HETEMetabolite70608-72-9 (CAS)
AAMetaboliteLMFA01030001 (LIPID MAPS)
Alox5Protein11689 (Entrez Gene)
GPMetaboliteCHEBI:37739 (ChEBI)
PGD2MetaboliteQ419750 (Wikidata)
PGE2MetaboliteLMFA03010003 (LIPID MAPS)
PGF2aMetaboliteLMFA03010002 (LIPID MAPS)
PGG2MetaboliteLMFA03010009 (LIPID MAPS)
PGH2MetaboliteLMFA03010010 (LIPID MAPS)
PGJ2MetaboliteQ27088353 (Wikidata)
Pla2g4aProtein18783 (Entrez Gene)
Pla2g4bProtein211429 (Entrez Gene)
Pla2g5Protein18784 (Entrez Gene)
Pla2g6Protein53357 (Entrez Gene)
PtgdsProteinO09114 (Uniprot-TrEMBL)
PtgesProtein64292 (Entrez Gene)
Ptgs1Protein74451 (Entrez Gene)
Ptgs2Protein19225 (Entrez Gene)

Annotated Interactions

No annotated interactions

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