Programmed cell death (Caenorhabditis elegans)
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Description
Programmed Cell Death pathway.
Based on conference notes, european worm meeting 2004
Quality Tags
Ontology Terms
Bibliography
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- Gartner A, Boag PR, Blackwell TK; ''Germline survival and apoptosis.''; WormBook, 2008 PubMed Europe PMC Scholia
- Gartner A, Milstein S, Ahmed S, Hodgkin J, Hengartner MO; ''A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans.''; Mol Cell, 2000 PubMed Europe PMC Scholia
- Hofmann ER, Milstein S, Boulton SJ, Ye M, Hofmann JJ, Stergiou L, Gartner A, Vidal M, Hengartner MO; ''Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis.''; Curr Biol, 2002 PubMed Europe PMC Scholia
- Derry WB, Putzke AP, Rothman JH; ''Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.''; Science, 2001 PubMed Europe PMC Scholia
- Schumacher B, Hofmann K, Boulton S, Gartner A; ''The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis.''; Curr Biol, 2001 PubMed Europe PMC Scholia
- Schumacher B, Schertel C, Wittenburg N, Tuck S, Mitani S, Gartner A, Conradt B, Shaham S; ''C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.''; Cell Death Differ, 2005 PubMed Europe PMC Scholia
- Schumacher B, Hanazawa M, Lee MH, Nayak S, Volkmann K, Hofmann ER, Hengartner M, Schedl T, Gartner A; ''Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis.''; Cell, 2005 PubMed Europe PMC Scholia
- Ahmed S, Alpi A, Hengartner MO, Gartner A; ''C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein.''; Curr Biol, 2001 PubMed Europe PMC Scholia
- Quevedo C, Kaplan DR, Derry WB; ''AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans.''; Curr Biol, 2007 PubMed Europe PMC Scholia
- Deng X, Hofmann ER, Villanueva A, Hobert O, Capodieci P, Veach DR, Yin X, Campodonico L, Glekas A, Cordon-Cardo C, Clarkson B, Bornmann WG, Fuks Z, Hengartner MO, Kolesnick R; ''Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation.''; Nat Genet, 2004 PubMed Europe PMC Scholia
- Gao MX, Liao EH, Yu B, Wang Y, Zhen M, Derry WB; ''The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans.''; Cell Death Differ, 2008 PubMed Europe PMC Scholia
- Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X; ''iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.''; Nat Genet, 2003 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
abl-1 | GeneProduct | WBGene00000018 (Ensembl) | |
akt-1 | GeneProduct | WBGene00000102 (Ensembl) | |
ape-1 | GeneProduct | WBGene00000146 (Ensembl) | |
ced-13 | GeneProduct | R09F10.9 (WormBase) | |
ced-3 | GeneProduct | WBGene00000417 (Ensembl) | |
ced-4 | GeneProduct | WBGene00000418 (Ensembl) | |
ced-9 | GeneProduct | WBGene00000423 (Ensembl) | |
cep-1 | GeneProduct | WBGene00000467 (Ensembl) | |
clk-2 | GeneProduct | WBGene00000537 (Ensembl) | |
egl-1 | GeneProduct | WBGene00001170 (Ensembl) | |
egl-38 | GeneProduct | C04G2.7 (WormBase) | |
fsn-1 | GeneProduct | WBGene00001499 (Ensembl) | |
gld-1 | GeneProduct | WBGene00001595 (Ensembl) | |
gld-3 | GeneProduct | WBGene00001597 (Ensembl) | |
hpr-9 | GeneProduct | WBGene00001997 (Ensembl) | |
hus-1 | GeneProduct | WBGene00002042 (Ensembl) | |
mrt-2 | GeneProduct | WBGene00003417 (Ensembl) | |
pax-2 | GeneProduct | WBGene00003938 (Ensembl) |
Annotated Interactions
No annotated interactions