Osteoblast signaling (Homo sapiens)
From WikiPathways
Description
Osteoblasts are specialized, terminally differentiated cell of mesenchymal origin. They create dense, crosslinked collagen and also specialized proteins, including osteocalcin and osteopontin. This pathway illustrates various signaling pathways in osteoblasts relevant to collagen and protein production.
Proteins on this pathway have targeted assays available via the CPTAC Assay Portal
Quality Tags
Ontology Terms
Bibliography
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History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Bone sialoprotein | Protein | 3381 (Entrez Gene) | |
Collagen 1 | Protein | 1277 (Entrez Gene) | |
FGF-23 | Protein | 8074 (Entrez Gene) | |
ITGAV | Protein | 3685 (Entrez Gene) | |
ITGB3 | Protein | 3690 (Entrez Gene) | |
NPT3 | Protein | 10246 (Entrez Gene) | |
Na+ | Metabolite | CHEBI:29101 (ChEBI) | |
Osteocalcin | Protein | 632 (Entrez Gene) | |
Osteoprotegerin | Protein | 4982 (Entrez Gene) | |
PDGF Ra | GeneProduct | 5156 (Entrez Gene) | |
PDGF Rb | GeneProduct | 5155 (Entrez Gene) | |
PDGFB | Protein | 5155 (Entrez Gene) | |
PDGFRA | Protein | 5156 (Entrez Gene) | |
PDGFRB | Protein | 5159 (Entrez Gene) | |
PTH receptor | Protein | 5745 (Entrez Gene) | |
Parathyroid hormone | Protein | 5741 (Entrez Gene) | |
Phosphate | Metabolite | 1061 (PubChem-compound) | |
RANK ligand | Protein | 8600 (Entrez Gene) | |
Soluble RANK ligand | Protein | 8600 (Entrez Gene) | |
Vitamin D | Metabolite | HMDB0000876 (HMDB) |
Annotated Interactions
No annotated interactions