Triacylglyceride synthesis (Homo sapiens)

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Only 1 of these enzymes is neededDegradationpathOnly 1 of these enzymes is neededPPAP2CPNPLA2GlycerolFatty acyl CoAGlycerol-3-phosphateGPAMAGPAT1AGPAT3AGPSPPAP2ADihydroxyacetone phosphateDGAT1DiacylglycerolLIPCPPAP2BAYR1MOGAT3Lysophosphatidic acidGK2GPD1DGAT2TriacylglycerolPhosphatidic acidLIPFFatty acyl CoAAGPAT5Fatty acyl CoALIPEAGPAT2Dihydroxyacetone phosphateGNPATMOGAT1MOGAT2Fatty acid synthesisAGPAT4LPLGKAcyl dihydroxyacetone phosphateMonoacylglycerol


Description

Triacylglyceride (or triglyceride) is a major component of skin oils, animal and vegetable fats, and supports the transfer of adipose and glucose between the liver and circulatory system. Triacylglyceride is synthesized from glycerol and three fatty acids. The terminal step of synthesis is performed by Diglyceride acyltransferase (DGAT).

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
129570view22:19, 13 May 2024EweitzEconomize layout
129569view15:34, 13 May 2024EweitzAlign nodes
129568view15:32, 13 May 2024EweitzAlign graphics
129567view15:31, 13 May 2024EweitzEconomize layout, standardize case
126355view20:42, 23 April 2023AlexanderPicotrigger resync
126330view06:03, 22 April 2023EgonwLicense is CCZero
123953view19:50, 7 September 2022AlexanderPicoModified description
116669view12:50, 9 May 2021EweitzModified title
115325view09:20, 13 February 2021EgonwMade another pathway clickable
107140view14:22, 17 September 2019MaintBotChEBI identifier normalization
106733view13:21, 17 September 2019MaintBotHMDB identifier normalization
97989view20:51, 28 June 2018KhanspersModified description
97988view20:50, 28 June 2018Khanspersremoved GenMAPP notes
97826view15:32, 9 June 2018EgonwUndo revision 97760 by [[Special:Contributions/Jessev1993|Jessev1993]] ([[User talk:Jessev1993|Talk]]) Text cannot be copied from other websites.
97760view13:27, 7 June 2018Jessev1993Modified description
71223view20:18, 15 October 2013MaintBotUpdated KEGG Compound xrefs
68917view17:31, 8 July 2013MaintBotUpdated to 2013 gpml schema
48243view06:10, 17 May 2012MaintBotUpdating PubChem xrefs
45059view19:55, 6 October 2011KhanspersOntology Term : 'triacylglycerol biosynthetic pathway' added !
43910view12:28, 16 August 2011AdrienDefayadd database name to pathway link
41062view23:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
38844view17:43, 24 September 2010Khanspers
38699view19:25, 23 September 2010KhanspersAdded pathway link, changed layout
37860view19:28, 12 July 2010KhanspersReverted to version '18:22, 10 December 2009' by Khanspers
37859view19:25, 12 July 2010Khansperschanged layout
34451view18:22, 10 December 2009MaintBotAutomatic update of empty xrefs
32399view17:01, 15 August 2009MaintBotFixed text labels
32050view13:31, 14 August 2009MaintBotFixed group labels
21363view11:31, 14 November 2008MaintBot[[Pathway:Homo sapiens:Triacylglyceride Synthesis BiGCaT]] moved to [[Pathway:WP325]]: Moved to stable identifier
19099view12:58, 17 September 2008EveloReverted to entrez gene
19097view12:55, 17 September 2008EveloTrying Swissprot identifier for MOGAT1
19095view12:52, 17 September 2008EveloRevert in between changes
19093view12:45, 17 September 2008EveloPeriodical save, work in progress
19091view12:36, 17 September 2008EveloCorrected backpage properties for MOGATS
19085view12:19, 17 September 2008EveloAdapted MGATs to MOGATs as commented by Bjorn Akeson
14605view06:46, 23 May 2008AlexanderPicoConnected catalytic enzymes
14602view06:44, 23 May 2008AlexanderPicoPeriodical save, work in progress
14588view06:29, 23 May 2008AlexanderPicoConnected!
14586view06:25, 23 May 2008AlexanderPicoPeriodical save, work in progress
14583view06:14, 23 May 2008AlexanderPicoPeriodical save, work in progress
14580view06:04, 23 May 2008AlexanderPicoPeriodical save, work in progress
14577view06:02, 23 May 2008AlexanderPicoFixed groups and metabolites
14565view05:34, 23 May 2008AlexanderPicoPeriodical save, work in progress
13125view11:17, 17 May 2008MaintBotautomated metabolite conversion
8458view13:46, 7 January 2008MaintBot[[Pathway:Human:Triacylglyceride Synthesis BiGCaT]] moved to [[Pathway:Homo sapiens:Triacylglyceride Synthesis BiGCaT]]: Renaming species
7845view16:22, 18 December 2007MaintBotfixed category names
7404view12:42, 4 November 2007MaintBotAdded categories to GPML
6401view22:18, 22 May 2007Evelogpml file for [[Human:Triacylglyceride_Synthesis_BiGCaT]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AGPAT1GeneProduct10554 (Entrez Gene)
AGPAT2GeneProduct10555 (Entrez Gene)
AGPAT3GeneProduct56894 (Entrez Gene)
AGPAT4GeneProduct56895 (Entrez Gene)
AGPAT5GeneProduct55326 (Entrez Gene)
AGPSGeneProduct8540 (Entrez Gene)
AYR1GeneProductYeast
Acyl dihydroxyacetone phosphateMetaboliteC03372 (KEGG Compound)
DGAT1GeneProduct8694 (Entrez Gene)
DGAT2GeneProduct84649 (Entrez Gene)
DiacylglycerolMetaboliteC00165 (KEGG Compound)
Dihydroxyacetone phosphateMetabolite57-04-5 (CAS)
Dihydroxyacetone phosphateMetaboliteHMDB0001473 (HMDB)
Fatty acid synthesisPathwayWP357 (WikiPathways)
Fatty acyl CoAMetaboliteCHEBI:37554 (ChEBI)
GK2GeneProduct2712 (Entrez Gene)
GKGeneProduct2710 (Entrez Gene)
GNPATGeneProduct8443 (Entrez Gene)
GPAMGeneProduct57678 (Entrez Gene)
GPD1GeneProduct2819 (Entrez Gene)
Glycerol-3-phosphateMetaboliteC00093 (KEGG Compound)
GlycerolMetabolite56-81-5 (CAS)
LIPCGeneProduct3990 (Entrez Gene)
LIPEGeneProduct3991 (Entrez Gene)
LIPFGeneProduct8513 (Entrez Gene)
LPLGeneProduct4023 (Entrez Gene)
Lysophosphatidic acidMetabolite5497152 (PubChem-compound)
MOGAT1GeneProduct116255 (Entrez Gene)
MOGAT2GeneProduct80168 (Entrez Gene)
MOGAT3GeneProduct346606 (Entrez Gene)
MonoacylglycerolMetaboliteC01885 (KEGG Compound)
PNPLA2GeneProduct57104 (Entrez Gene)
PPAP2AGeneProduct8611 (Entrez Gene)
PPAP2BGeneProduct8613 (Entrez Gene)
PPAP2CGeneProduct8612 (Entrez Gene)
Phosphatidic acidMetabolite5460104 (PubChem-compound)
TriacylglycerolMetaboliteC00422 (KEGG Compound)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP325"
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