Fatty acid biosynthesis (Mus musculus)

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CytosolAcetoacetyl-ACPPalmitoyl-ACPOxaloacetateAcetyl-ACPMitochondrion6 iterationsTCA CyclePyruvateButyryl-ACPLong-Chain fatty acidCrotonoyl-ACPtrans-delta2-enoyl-CoAless than 6 iterationsFatty acyl CoACitratePalmitate3-ketoacyl-CoA3-L-Hydroxyacyl-CoAAcetyl-synthaseMalonyl-ACPbeta-hydroxybutyrylMalonyl-CoAAcetyl-CoAAclyAcacaFasnFasnFasnEchdc3Echdc1FasnFasnMecrAcss2FasnFasnScd1Acsl3Acyl-CoA (n+2)Echs1PcxEchdc2Acsl1Ech1Acsl6Acsl4Acsl5HadhPecrDecr1AcacbAcaa2Triacylglyceride Synthesis pathwayFasn


Description

The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP357(r30271) with a 90% conversion rate.

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
125350view19:47, 3 February 2023AlexanderPicoupdated descriptions
123112view07:02, 4 July 2022EgonwMade a pathway clickable
117884view10:22, 23 May 2021EweitzModified title
106878view13:35, 17 September 2019MaintBotHMDB identifier normalization
90165view14:13, 20 October 2016Mkutmonfix unconnected lines
71737view20:17, 17 October 2013MaintBotAutomated update of data sources
69120view18:14, 8 July 2013MaintBotUpdated to 2013 gpml schema
67239view10:25, 26 June 2013Christine ChichesterOntology Term : 'fatty acid biosynthetic pathway' added !
41307view00:23, 2 March 2011MaintBotRemoved redundant pathway information and comments
38674view15:16, 23 September 2010BassetfrogAdded link for Triacylglyceride Synthesis pathway
32876view22:27, 16 September 2009MaintBotAdded xrefs
32054view13:32, 14 August 2009MaintBotFixed group labels
30860view00:10, 30 July 2009MaintBotConverted from Homo sapiens
21385view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:Fatty Acid Synthesis BiGCaT]] moved to [[Pathway:WP336]]: Moved to stable identifier
8054view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Fatty Acid Synthesis BiGCaT]] moved to [[Pathway:Mus musculus:Fatty Acid Synthesis BiGCaT]]: Renaming species
7649view16:07, 18 December 2007MaintBotfixed category names
7358view12:42, 4 November 2007MaintBotAdded categories to GPML
19461view22:18, 22 May 2007Evelogpml file for [[Mouse:Fatty_Acid_Synthesis_BiGCaT]]
6442view22:18, 22 May 2007Kdahlquistgpml file for [[Mouse:Fatty_Acid_Synthesis_BiGCaT]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Acaa2GeneProduct52538 (Entrez Gene)
AcacaGeneProduct107476 (Entrez Gene)
AcacbGeneProduct100705 (Entrez Gene)
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
AclyGeneProduct104112 (Entrez Gene)
Acsl1GeneProduct14081 (Entrez Gene)
Acsl3GeneProduct74205 (Entrez Gene)
Acsl4GeneProduct50790 (Entrez Gene)
Acsl5GeneProduct433256 (Entrez Gene)
Acsl6GeneProduct216739 (Entrez Gene)
Acss2GeneProduct60525 (Entrez Gene)
Acyl-CoA (n+2)Metabolite
Decr1GeneProduct67460 (Entrez Gene)
Ech1GeneProduct51798 (Entrez Gene)
Echdc1GeneProduct52665 (Entrez Gene)
Echdc2GeneProduct52430 (Entrez Gene)
Echdc3GeneProduct67856 (Entrez Gene)
Echs1GeneProduct93747 (Entrez Gene)
FasnGeneProduct14104 (Entrez Gene)
HadhGeneProduct15107 (Entrez Gene)
Malonyl-CoAMetaboliteHMDB0001175 (HMDB)
MecrGeneProduct26922 (Entrez Gene)
PcxGeneProduct18563 (Entrez Gene)
PecrGeneProduct111175 (Entrez Gene)
Scd1GeneProduct20249 (Entrez Gene)
Triacylglyceride Synthesis pathwayPathwayWP386 (WikiPathways)

Annotated Interactions

No annotated interactions
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