Signal transduction of S1P receptor (Mus musculus)
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Description
This is a representation of figure 2 from T. Hla, et al. 2001, Science, 294, pg. 1877.
Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine.
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DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Akt1 | GeneProduct | 11651 (Entrez Gene) | |
Akt2 | GeneProduct | 11652 (Entrez Gene) | |
Akt3 | GeneProduct | 23797 (Entrez Gene) | |
Asah2 | GeneProduct | 54447 (Entrez Gene) | |
Edg1 | GeneProduct | 13609 (Entrez Gene) | |
Edg3 | GeneProduct | 13610 (Entrez Gene) | |
Edg5 | GeneProduct | 14739 (Entrez Gene) | |
Edg8 | GeneProduct | 94226 (Entrez Gene) | |
Gnai1 | GeneProduct | 14677 (Entrez Gene) | |
Gnai2 | GeneProduct | 14678 (Entrez Gene) | |
Gnai3 | GeneProduct | 14679 (Entrez Gene) | |
Mapk12 | GeneProduct | 29857 (Entrez Gene) | |
Mapk1 | GeneProduct | 26413 (Entrez Gene) | |
Mapk3 | GeneProduct | 26417 (Entrez Gene) | |
Mapk6 | GeneProduct | 50772 (Entrez Gene) | |
Mapk7 | GeneProduct | 23939 (Entrez Gene) | |
Pik3c2g | GeneProduct | 18705 (Entrez Gene) | |
Plcb3 | GeneProduct | 18797 (Entrez Gene) | |
Racgap1 | GeneProduct | 26934 (Entrez Gene) | |
Smpd2 | GeneProduct | 20598 (Entrez Gene) | |
Sphk1 | GeneProduct | 20698 (Entrez Gene) | |
Sphk2 | GeneProduct | 56632 (Entrez Gene) |
Annotated Interactions
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