Asparagine biosynthesis (Saccharomyces cerevisiae)
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Description
The precursor to asparagine is oxaloacetate, which the AAT enzyme converts to aspartate by transferring the amino group from glutamate to oxaloacetate, producing α-ketoglutarate and aspartate. The enzyme ASN produces asparagine, AMP, glutamate, and pyrophosphate from aspartate, glutamine, and ATP.
Description adapted from Wikipedia.
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Ontology Terms
Bibliography
- ''L-asparagine biosynthesis I''; YeastPathways,
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
2-oxoglutarate | Metabolite | CHEBI:16810 (ChEBI) | |
AAT1 | GeneProduct | S000001589 (SGD) | |
AAT2 | GeneProduct | S000004017 (SGD) | |
AMP | Metabolite | CHEBI:16027 (ChEBI) | |
ASN1 | GeneProduct | S000006349 (SGD) | |
ASN2 | GeneProduct | S000003356 (SGD) | |
ATP | Metabolite | 1927-31-7 (CAS) | |
H2O | Metabolite | HMDB02111 (HMDB) | |
L-asparagine | Metabolite | 70-47-3 (CAS) | |
L-aspartate | Metabolite | CHEBI:29991 (ChEBI) | |
L-glutamate | Metabolite | 56-86-0 (CAS) | |
L-glutamine | Metabolite | 56-85-9 (CAS) | |
Oxaloacetic acid | Metabolite | CHEBI:30744 (ChEBI) | |
pyrophosphate | Metabolite | 2466-09-3 (CAS) |
Annotated Interactions
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