Catecholamine synthesis (Rattus norvegicus)
From WikiPathways
Description
This pathway was created using information from:
- http://biocyc.org/META/new-image?type=PATHWAY&object=PWY66-301
- http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/AminoAcid/dopa.html
- http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/AminoAcid/PheTyr.html
- http://www.genome.ad.jp/dbget-bin/www_bget?pathway+map00350
- http://www.genome.jp/dbget-bin/get_pathway?org_name=rno&mapno=00400 (phenylalanine -> tyrosine)
Quality Tags
Ontology Terms
Bibliography
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- Pigeon D, Drissi-Daoudi R, Gros F, Thibault J; ''[Copurification of tyrosine hydroxylase from rat pheochromocytoma by protein kinase]''; C R Acad Sci III, 1986 PubMed Europe PMC Scholia
- LOVENBERG W, WEISSBACH H, UDENFRIEND S; ''Aromatic L-amino acid decarboxylase.''; J Biol Chem, 1962 PubMed Europe PMC Scholia
- Kaufman S; ''The enzymic conversion of phenylalanine to tyrosine''; J. Biol. Chem, 1957 PubMed Europe PMC Scholia
- Ikeda M, Levitt M, Udenfriend S; ''Phenylalanine as substrate and inhibitor of tyrosine hydroxylase.''; Arch Biochem Biophys, 1967 PubMed Europe PMC Scholia
- Levin Eprham Y., Kaufman S; ''Studies on the enzyme catalyzing the conversion of 3,4-Dihydroxyphenylethylamine to Norepinhephrine''; J Biol Chemistry, 1961 PubMed Europe PMC Scholia
- McGilvery, R.W., Cohen, P.P.; ''The decarboxylation of L-phenylalanine by Streptococcus faecalis R.''; J. Biol. Chem. 174, 1948 PubMed Europe PMC Scholia
- Christenson JG, Dairman W, Udenfriend S; ''On the identity of DOPA decarboxylase and 5-hydroxytryptophan decarboxylase (immunological titration-aromatic L-amino acid decarboxylase-serotonin-dopamine-norepinephrine).''; Proc Natl Acad Sci U S A, 1972 PubMed Europe PMC Scholia
- Sekeris, C.E.; ''Zur Tyrosinstoffwechsel der Insekten. XII. Reinigung, Eigenschaften und Substratspezifität der DOPA-Decarboxylase Hoppe-Seyler's Z.''; Physiol. Chem. 332, 1963 PubMed Europe PMC Scholia
- Udenfriend, S, Cooper, J.R; ''The chemical estimation of tyrosine and tyramine''; J. Biol. Chem, 1952 PubMed Europe PMC Scholia
- Goodwill KE, Sabatier C, Marks C, Raag R, Fitzpatrick PF, Stevens RC; ''Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases.''; Nat Struct Biol, 1997 PubMed Europe PMC Scholia
- Carr RT, Balasubramanian S, Hawkins PC, Benkovic SJ; ''Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase.''; Biochemistry, 1995 PubMed Europe PMC Scholia
- Sekeris, C.E.; ''Zur Tyrosinstoffwechsel der Insekten. XII. Reinigung, Eigenschaften und Substratspezifität der DOPA-Decarboxylase Hoppe-Seyler's Z.''; Physiol. Chem. 332, 1963 PubMed Europe PMC Scholia
- El Mestikawy S, Glowinski J, Hamon M; ''Tyrosine hydroxylase activation in depolarized dopaminergic terminals--involvement of Ca2+-dependent phosphorylation.''; Nature, 1983 PubMed Europe PMC Scholia
- Levin, E.Y., Levenberg, B., Kaufman, S.; ''The enzymatic conversion of 3,4-dihydroxyphenylethylamine to norepinephrine''; J Biol Chem, 1960 PubMed Europe PMC Scholia
- Levin, E.Y., Levenberg, B., Kaufmann, S.; ''The enzymatic conversion of 3,4-dihydroxyphenylethylamine to norepinephrine.''; J. Biol. Chem. 235, 1960 PubMed Europe PMC Scholia
- Connett RJ, Kirshner N; ''Purification and properties of bovine phenylethanolamine N-methyltransferase.''; J Biol Chem, 1970 PubMed Europe PMC Scholia
- Ishida Y, Yokoyama C, Inatomi T, Yagita K, Dong X, Yan L, Yamaguchi S, Nagatsu I, Komori T, Kitahama K, Okamura H; ''Circadian rhythm of aromatic L-amino acid decarboxylase in the rat suprachiasmatic nucleus: gene expression and decarboxylating activity in clock oscillating cells.''; Division of Molecular Brain Science, Department of Brain Sciences, Kobe University Graduate School of Medicine, Chuo-ku, Kobe 650-0017, Japan., 2002 PubMed Europe PMC Scholia
- Kaufman S; ''Studies on the mechanism of the enzymatic conversion of phenylalanine to tyrosine''; J. Biol. Chem, 1959 PubMed Europe PMC Scholia
- Nagatsu, T., Levitt, M., Udenfriend, S; ''Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis.''; J. Biol. Chem. 239, 1964 PubMed Europe PMC Scholia
- Nagatsu, T., Levitt, M., Udenfriend, S.; ''Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis.''; J. Biol. Chem. 239, 1964 PubMed Europe PMC Scholia
- Friedman S, Kaufman S; ''3,4-dihydroxyphenylethylamine beta-hydroxylase. Physical properties, copper content, and role of copper in the catalytic acttivity.''; J Biol Chem, 1965 PubMed Europe PMC Scholia
- Guroff G, Rhoads CA; ''Phenylalanine hydroxylation by Pseudomonas species (ATCC 11299a). Nature of the cofactor.''; J Biol Chem, 1969 PubMed Europe PMC Scholia
- Axelrod, J.; ''Purification and properties of phenylethanolamine-N-methyl transferase.''; J. Biol. Chem. 237, 1962 PubMed Europe PMC Scholia
- Axelrod, J.; ''Purification and properties of phenylethanolamine-N-methyl transferase.''; J.Biol.Chem, 1962 PubMed Europe PMC Scholia
- WEISSBACH H, BOGDANSKI DF, REDFIELD BG, UDENFRIEND S; ''Studies on the effect of vitamin B6 on 5-hydroxytryptamine (serotonin) formation.''; J Biol Chem, 1957 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
4a-hydroxy-tetrahydrobiopterin | Metabolite | 23724532 (PubChem-compound) | |
AdoHcy | Metabolite | HMDB0000939 (HMDB) | |
AdoMet | Metabolite | 90473 (PubChem-compound) | |
Adrenaline | Metabolite | HMDB0000068 (HMDB) | |
Ascorbate | Metabolite | HMDB0000044 (HMDB) | |
CO2 | Metabolite | ||
Dbh | GeneProduct | 25699 (Entrez Gene) | |
Ddc | GeneProduct | 24311 (Entrez Gene) | |
Dehydroascorbate | Metabolite | HMDB0001264 (HMDB) | |
Dopamine | Metabolite | HMDB0000073 (HMDB) | |
H2O | Metabolite | ||
L-DOPA | Metabolite | HMDB0000609 (HMDB) | |
L-tyrosine | Metabolite | HMDB0000158 (HMDB) | |
Noradrenaline | Metabolite | HMDB0000216 (HMDB) | |
O2 | Metabolite | ||
Pah | GeneProduct | 24616 (Entrez Gene) | |
Phenylalanine | Metabolite | HMDB0000159 (HMDB) | |
Pnmt | GeneProduct | 24661 (Entrez Gene) | |
Th | GeneProduct | 25085 (Entrez Gene) | |
tetrahydrobiopterin | Metabolite | HMDB0000027 (HMDB) |
Annotated Interactions
No annotated interactions