Transcription co-factors SKI and SKIL protein partners (Homo sapiens)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Transcription co-factors SKI and SKIL protein partners" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">Several proteins are partners of SKI and / or SKIL. The interacting domains are often not identified.</Comment> <BiopaxRef>a19</BiopaxRef> <Graphics BoardWidth="649.0274999999998" BoardHeight="884.2475000000002"/> <DataNode TextLabel="TEAD1" Type="GeneProduct" GroupRef="f29cb"> <Comment Source="OCR">Tead1-4</Comment> <Graphics CenterX="119.1424999999999" CenterY="166.2575000000002" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="7003"/> </DataNode> <DataNode TextLabel="TEAD2" Type="GeneProduct" GroupRef="f29cb"> <Comment Source="OCR">Tead1-4</Comment> <Graphics CenterX="119.1424999999999" CenterY="191.25750000000022" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="8463"/> </DataNode> <DataNode TextLabel="TEAD3" Type="GeneProduct" GroupRef="f29cb"> <Comment Source="OCR">Tead1-4</Comment> <Graphics CenterX="119.1424999999999" CenterY="216.25750000000025" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="7005"/> </DataNode> <DataNode TextLabel="TEAD4" Type="GeneProduct" GroupRef="f29cb"> <Comment Source="OCR">Tead1-4</Comment> <Graphics CenterX="119.1424999999999" CenterY="241.25750000000028" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="7004"/> </DataNode> <DataNode TextLabel="LATS1" GraphId="a52d0" Type="GeneProduct"> <Comment Source="OCR">Lats1</Comment> <Graphics CenterX="493.54499999999973" CenterY="469.84999999999997" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="9113"/> </DataNode> <DataNode TextLabel="Mob" GraphId="a7b38" Type="GeneProduct"> <Graphics CenterX="525.8925000000004" CenterY="226.01249999999956" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="LATS2" GraphId="ac9e5" Type="GeneProduct"> <Comment Source="OCR">Lats2</Comment> <Graphics CenterX="206.89500000000004" CenterY="311.3224999999993" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="26524"/> </DataNode> <DataNode TextLabel="SKIL" GraphId="ad85d" Type="GeneProduct"> <Comment Source="OCR">SnoN</Comment> <Graphics CenterX="357.28249999999946" CenterY="364.4749999999998" Width="90.0" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="6498"/> </DataNode> <DataNode TextLabel="MECP2" GraphId="af362" Type="GeneProduct"> <Comment Source="OCR">MeCP2</Comment> <Graphics CenterX="248.78999999999988" CenterY="485.74999999999983" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="4204"/> </DataNode> <DataNode TextLabel="Sav" GraphId="b36d6" Type="GeneProduct"> <Graphics CenterX="511.5600000000001" CenterY="310.9049999999992" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="SATB2" GraphId="b720f" Type="GeneProduct"> <Comment Source="OCR">Satb2</Comment> <Graphics CenterX="188.9274999999999" CenterY="118.21250000000036" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="23314"/> </DataNode> <DataNode TextLabel="MERTK" GraphId="b8838" Type="GeneProduct"> <Comment Source="OCR">Mer</Comment> <Graphics CenterX="545.3625" CenterY="164.05249999999975" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="10461"/> </DataNode> <DataNode TextLabel="NF1" GraphId="d0c4b" Type="GeneProduct"> <Comment Source="OCR">NF1</Comment> <Graphics CenterX="500.9350000000003" CenterY="120.12500000000044" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="4763"/> </DataNode> <DataNode TextLabel="ING2" GraphId="e685d" Type="GeneProduct"> <Comment Source="OCR">ING2</Comment> <Graphics CenterX="532.4600000000002" CenterY="400.0474999999997" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="3622"/> </DataNode> <DataNode TextLabel="SKI" GraphId="e7b6b" Type="GeneProduct"> <Comment Source="OCR">Ski</Comment> <Graphics CenterX="353.97500000000025" CenterY="264.2074999999994" Width="90.00000000000007" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="6497"/> </DataNode> <DataNode TextLabel="HDAC1" GraphId="e9f73" Type="GeneProduct"> <Comment Source="OCR">HDAC1</Comment> <Graphics CenterX="456.38749999999976" CenterY="82.0625000000001" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="3065"/> </DataNode> <DataNode TextLabel="PRMT5" GraphId="ecb2f" Type="GeneProduct"> <Comment Source="OCR">PRMT5</Comment> <Graphics CenterX="245.15500000000023" CenterY="80.26250000000049" Width="90.00000000000007" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="10419"/> </DataNode> <DataNode TextLabel="HDAC3" GraphId="f1226" Type="GeneProduct"> <Graphics CenterX="352.80000000000035" CenterY="82.68749999999982" Width="90.00000000000007" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000171720"/> </DataNode> <DataNode TextLabel="STK3" GraphId="fad5c" Type="GeneProduct"> <Comment Source="OCR">Mst2</Comment> <Graphics CenterX="357.2824999999994" CenterY="505.1900000000001" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Entrez Gene" ID="6788"/> </DataNode> <DataNode TextLabel="SIN3A" GraphId="fdf41" Type="GeneProduct"> <Graphics CenterX="153.24749999999997" CenterY="396.9000000000001" Width="90.00000000000004" Height="25.00000000000002" ZOrder="32768" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000169375"/> </DataNode> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="267.6550000000002" Y="92.76250000000041"/> <Point X="353.97500000000025" Y="251.7074999999994" GraphRef="e7b6b" RelX="0.0" RelY="-1.0"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="352.8000000000003" Y="95.18749999999983" GraphRef="f1226" RelX="0.0" RelY="1.0"/> <Point X="353.97500000000025" Y="251.7074999999994" GraphRef="e7b6b" RelX="0.0" RelY="-1.0"/> </Graphics> <Xref Database="" ID=""/> 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rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Transcriptional cofactors Ski and SnoN are major regulators of the TGF-β/Smad signaling pathway in health and disease.</bp:TITLE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2018</bp:YEAR> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Signal Transduct Target Ther</bp:SOURCE> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tecalco-Cruz AC</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ríos-López DG</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Vázquez-Victorio G</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Rosales-Alvarez RE</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Macías-Silva M</bp:AUTHORS> </bp:PublicationXref> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>transcription pathway</bp:TERM><bp:ID>PW:0000100</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary></Biopax> </Pathway>

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