Differentiation of white and brown adipocyte (Bos taurus)

From WikiPathways

You do not have permission to edit pages, for the following reasons:

• You do not have permission to edit pages in the Pathway namespace.
• You are not allowed to execute the action you have requested.

You can view and copy the source of this page:

<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Differentiation of white and brown adipocyte" Version="20150206" Organism="Bos taurus"> <Comment Source="WikiPathways-description">Development of white versus brown adipocytes (figure from Handbook of Obesity). Transcription factors and nuclear regulators controlling the development of white versus brown adipocytes are shown in the pathway. At the bottom a selection of identified markers of white and brown adipocytes were added (from Nascimento et al). </Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://wikipathways.org/instance/WP2895_r79216 WP2895(79216)] with a 90.0% conversion rate.</Comment> <BiopaxRef>c7d</BiopaxRef> <BiopaxRef>f7c</BiopaxRef> <Graphics BoardWidth="649.9614740693465" BoardHeight="594.4599413781029"/> <DataNode TextLabel="OB" GraphId="b284c" Type="GeneProduct" GroupRef="b370e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000174697</Comment> <Graphics CenterX="171.68584019685167" CenterY="445.14246961812665" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014911"/> </DataNode> <DataNode TextLabel="ADIPOQ" GraphId="b1c1a" Type="GeneProduct" GroupRef="b370e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000181092</Comment> <Graphics CenterX="171.68584019685167" CenterY="465.14246961812665" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000019813"/> </DataNode> <DataNode TextLabel="SLC7A10" GraphId="b6710" Type="GeneProduct" GroupRef="b370e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000130876</Comment> <Graphics CenterX="171.68584019685167" CenterY="485.14246961812665" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000046544"/> </DataNode> <DataNode TextLabel="HOXC8" GraphId="f5d95" Type="GeneProduct" GroupRef="b370e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000037965</Comment> <Graphics CenterX="171.68584019685167" CenterY="505.14246961812694" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012149"/> </DataNode> <DataNode TextLabel="HOXC9" GraphId="cb567" Type="GeneProduct" GroupRef="b370e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000180806</Comment> <Graphics CenterX="171.68584019685167" CenterY="525.1424696181263" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000005606"/> </DataNode> <DataNode TextLabel="PRDM16" GraphId="e54fa" Type="GeneProduct" GroupRef="c1b7f"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000142611</Comment> <Graphics CenterX="497.860557796624" CenterY="446.4599413781038" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018965"/> </DataNode> <DataNode TextLabel="CIDEA" GraphId="deb7e" Type="GeneProduct" GroupRef="c1b7f"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000176194</Comment> <Graphics CenterX="497.860557796624" CenterY="466.4599413781038" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000047609"/> </DataNode> <DataNode TextLabel="EBF3" GraphId="af0d9" Type="GeneProduct" GroupRef="c1b7f"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108001</Comment> <Graphics CenterX="497.860557796624" CenterY="506.4599413781037" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000008272"/> </DataNode> <DataNode TextLabel="HSPB7" GraphId="c9e9b" Type="GeneProduct" GroupRef="c1b7f"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000173641</Comment> <Graphics CenterX="497.860557796624" CenterY="526.4599413781034" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000010940"/> </DataNode> <DataNode TextLabel="ZIC1" GraphId="a664c" Type="GeneProduct" GroupRef="c1b7f"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000152977</Comment> <Graphics CenterX="497.860557796624" CenterY="546.4599413781029" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014751"/> </DataNode> <DataNode TextLabel="MPZL2" GraphId="de24f" Type="GeneProduct" GroupRef="c1b7f"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000149573</Comment> <Graphics CenterX="497.860557796624" CenterY="486.4599413781038" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000033510"/> </DataNode> <DataNode TextLabel="BMP2" GraphId="aaaa1" Type="GeneProduct" GroupRef="be6d7"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000125845</Comment> <Graphics CenterX="142.5315957315404" CenterY="98.1057929329171" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000005111"/> </DataNode> <DataNode TextLabel="BMP4" GraphId="aaaa2" Type="GeneProduct" GroupRef="be6d7"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000125378</Comment> <Graphics CenterX="142.5315957315404" CenterY="118.10579293291711" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000003835"/> </DataNode> <DataNode TextLabel="SMAD1" GraphId="aaaa3" Type="GeneProduct" GroupRef="be6d7"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000170365</Comment> <Graphics CenterX="142.5315957315404" CenterY="138.10579293291707" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002835"/> </DataNode> <DataNode TextLabel="SMAD5" GraphId="c7ee5" Type="GeneProduct" GroupRef="be6d7"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000113658</Comment> <Graphics CenterX="142.5315957315404" CenterY="158.10579293291707" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000021772"/> </DataNode> <DataNode TextLabel="SMAD9" GraphId="aaaa4" Type="GeneProduct" GroupRef="be6d7"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000120693</Comment> <Graphics CenterX="142.5315957315404" CenterY="178.10579293291707" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000007589"/> </DataNode> <DataNode TextLabel="C/EBPβ" GraphId="aaaa5" Type="GeneProduct" GroupRef="ef19d"> <Graphics CenterX="567.9614740693465" CenterY="265.04645790681593" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="CEBPG" GraphId="aaaa6" Type="GeneProduct" GroupRef="eed7b"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000153879</Comment> <Graphics CenterX="116.78459383389715" CenterY="279.98289146696453" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000017560"/> </DataNode> <DataNode TextLabel="PRDM16" GraphId="aaaa7" Type="GeneProduct" GroupRef="ef19d"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000142611</Comment> <Graphics CenterX="567.9614740693465" CenterY="285.04645790681593" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018965"/> </DataNode> <DataNode TextLabel="ZNF423" GraphId="d676e" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000102935</Comment> <Graphics CenterX="337.90814251669207" CenterY="138.69603850598506" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000017397"/> </DataNode> <DataNode TextLabel="PPARG" GraphId="c5502" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000132170</Comment> <Graphics CenterX="334.42108011344004" CenterY="282.5128703178613" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000001333"/> </DataNode> <DataNode TextLabel="C/EBPα" GraphId="b288a" Type="GeneProduct"> <Graphics CenterX="334.42108011344004" CenterY="324.0851100953919" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="BMP7" GraphId="aaaa8" Type="GeneProduct" GroupRef="e9372"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000101144</Comment> <Graphics CenterX="565.3861835760674" CenterY="109.65041103565959" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000015362"/> </DataNode> <DataNode TextLabel="SMAD9" GraphId="aaaa9" Type="GeneProduct" GroupRef="e9372"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000120693</Comment> <Graphics CenterX="565.3861835760672" CenterY="169.65041103565963" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000007589"/> </DataNode> <DataNode TextLabel="PLAC8" GraphId="aaa10" Type="GeneProduct" GroupRef="ef19d"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000145287</Comment> <Graphics CenterX="567.9614740693465" CenterY="245.04645790681593" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000031750"/> </DataNode> <DataNode TextLabel="PRDM16" GraphId="faf43" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000142611</Comment> <Graphics CenterX="113.7370091138252" CenterY="345.7293465861187" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018965"/> </DataNode> <DataNode TextLabel="PPARGC1A" GraphId="aaa11" Type="GeneProduct" GroupRef="ae1e0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000109819</Comment> <Graphics CenterX="566.8027381893562" CenterY="343.28474194643934" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000017024"/> </DataNode> <DataNode TextLabel="PPARGC1B" GraphId="aaa12" Type="GeneProduct" GroupRef="ae1e0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000155846</Comment> <Graphics CenterX="566.8027381893562" CenterY="363.2847419464394" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012943"/> </DataNode> <DataNode TextLabel="SMAD5" GraphId="c65b9" Type="GeneProduct" GroupRef="e9372"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000113658</Comment> <Graphics CenterX="565.3861835760672" CenterY="149.6504110356596" Width="80.0" Height="20.0" ZOrder="32772" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000021772"/> </DataNode> <DataNode TextLabel="SMAD1" GraphId="aaa13" Type="GeneProduct" GroupRef="e9372"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000170365</Comment> <Graphics CenterX="565.3861835760672" CenterY="129.6504110356596" Width="80.0" Height="20.0" ZOrder="32773" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002835"/> </DataNode> <DataNode TextLabel="C/EBPβ" GraphId="aaa14" Type="GeneProduct" GroupRef="eed7b"> <Graphics CenterX="116.78459383389715" CenterY="259.98289146696453" Width="80.0" Height="20.0" ZOrder="32774" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <Interaction GraphId="idad89e69a"> <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0"> <Point X="252.84541867253495" Y="65.01392747577766" GraphRef="da6ba" RelX="-1.0" RelY="0.0"/> <Point X="239.20051579626048" Y="139.27652828711769"/> <Point X="259.68233183429174" Y="213.5391290984577" GraphRef="fe734" RelX="-1.0" RelY="0.0" ArrowHead="mim-conversion"/> <Anchor Position="0.4776912290175059" Shape="None" GraphId="e4579"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id82f39b21"> <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0"> <Point X="430.0451321727912" Y="65.01392747577766" GraphRef="da6ba" RelX="1.0" RelY="0.0"/> <Point X="438.0021626356779" Y="139.27652828711769"/> <Point X="411.4990096791382" Y="213.5391290984577" GraphRef="fe734" RelX="1.0" RelY="0.0" ArrowHead="mim-conversion"/> <Anchor Position="0.44573695309909256" Shape="None" GraphId="b6c0b"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="ida3dff87a"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="297.63650129550336" Y="223.5391290984577" GraphRef="fe734" RelX="-0.5" RelY="1.0"/> <Point X="172.00233338017966" Y="401.4977242925303" GraphRef="f3771" RelX="0.0" RelY="-1.0" ArrowHead="mim-conversion"/> <Anchor Position="0.6846535235136786" Shape="None" GraphId="a3967"/> <Anchor Position="0.2643541035650561" Shape="None" GraphId="af0af"/> <Anchor Position="0.33526298810403865" Shape="None" GraphId="fa4ad"/> <Anchor Position="0.5594135028680893" Shape="None" GraphId="c9b7d"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id8178e62b"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="373.5448402179266" Y="223.5391290984577" GraphRef="fe734" RelX="0.5" RelY="1.0"/> <Point X="495.1467665812802" Y="403.68366800608567" GraphRef="df77e" RelX="0.0" RelY="-1.0" ArrowHead="mim-conversion"/> <Anchor Position="0.5588849605022639" Shape="None" GraphId="d5988"/> <Anchor Position="0.32834593645737437" Shape="None" GraphId="bd860"/> <Anchor Position="0.23722108454879826" Shape="None" GraphId="bf296"/> <Anchor Position="0.7183637549948759" Shape="None" GraphId="fa368"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id8ee9eed1"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="377.90814251669207" Y="138.69603850598506" GraphRef="d676e" RelX="1.0" RelY="0.0"/> <Point X="438.0021626356779" Y="138.62024500322374" GraphRef="b6c0b" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idb11fea82"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="297.90814251669207" Y="138.69603850598506" GraphRef="d676e" RelX="-1.0" RelY="0.0"/> <Point X="251.01323573673184" Y="139.27652828711769" GraphRef="e4579" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id2f1bd5c6"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="194.5315957315404" Y="138.1057929329171" GraphRef="a1f6f" RelX="1.0" RelY="0.0"/> <Point X="251.01323573673184" Y="139.27652828711769" GraphRef="e4579" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id43dfb361"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="513.3861835760672" Y="139.6504110356596" GraphRef="afc95" RelX="-1.0" RelY="0.0"/> <Point X="438.0021626356779" Y="138.62024500322374" GraphRef="b6c0b" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id1ae91eb4"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="374.42108011344004" Y="282.5128703178613" GraphRef="c5502" RelX="1.0" RelY="0.0"/> <Point X="413.4723386047226" Y="282.6888564237647" GraphRef="bd860" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id3fbbc879"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="374.42108011344004" Y="324.0851100953919" GraphRef="b288a" RelX="1.0" RelY="0.0"/> <Point X="441.50632803050866" Y="324.2192026105459" GraphRef="d5988" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id54825b7d"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="294.42108011344004" Y="282.5128703178613" GraphRef="c5502" RelX="-1.0" RelY="0.0"/> <Point X="255.5160147522474" Y="283.2020594820195" GraphRef="fa4ad" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idca04ea58"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="294.42108011344004" Y="324.0851100953919" GraphRef="b288a" RelX="-1.0" RelY="0.0"/> <Point X="227.35505134207443" Y="323.0915702014582" GraphRef="c9b7d" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id5745c8d6"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="515.9614740693465" Y="265.04645790681593" GraphRef="fdc37" RelX="-1.0" RelY="0.0"/> <Point X="402.39138107306445" Y="266.2732119936684" GraphRef="bf296" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id7ee7774"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="514.8027381893562" Y="353.28474194643934" GraphRef="a15fc" RelX="-1.0" RelY="0.0"/> <Point X="460.8992566549157" Y="352.9484365099619" GraphRef="fa368" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idf964b9f3"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="168.78459383389713" Y="269.98289146696453" GraphRef="bcc90" RelX="1.0" RelY="0.0"/> <Point X="264.42459345910623" Y="270.58321400268346" GraphRef="af0af" RelX="0.0" RelY="0.0" ArrowHead="mim-stimulation"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id4ac970d9"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="153.7370091138252" Y="345.7293465861187" GraphRef="faf43" RelX="1.0" RelY="0.0"/> <Point X="211.62062555856784" Y="345.37910833762385" GraphRef="a3967" RelX="0.0" RelY="0.0" ArrowHead="mim-inhibition"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Label TextLabel="White Adipocyte" GraphId="b6646" GroupRef="b370e"> <Graphics CenterX="172.00233338017966" CenterY="419.4977242925303" Width="136.97534613454744" Height="20.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="cc0066"/> </Label> <Label TextLabel="Brown Adipocyte" GraphId="c32cf" GroupRef="c1b7f"> <Graphics CenterX="495.1467665812802" CenterY="421.68366800608567" Width="141.80868467771197" Height="20.0" ZOrder="32769" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="cc0066"/> </Label> <Label TextLabel="Preadipocyte" GraphId="fe734"> <Graphics CenterX="335.5906707567149" CenterY="213.53912909845772" Width="151.8166778448465" Height="19.999999999999986" ZOrder="32770" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="cc0066"/> </Label> <Label TextLabel="Vascular progenitors" GraphId="da6ba"> <Graphics CenterX="341.4452754226631" CenterY="65.01392747577766" Width="177.19971350025625" Height="20.0" ZOrder="32771" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" Color="cc0066"/> </Label> <Group GroupId="b370e" GraphId="f3771"> <BiopaxRef>c7d</BiopaxRef> </Group> <Group GroupId="c1b7f" GraphId="df77e"> <BiopaxRef>c7d</BiopaxRef> </Group> <Group GroupId="be6d7" GraphId="a1f6f" Style="Complex"/> <Group GroupId="e9372" GraphId="afc95" Style="Complex"/> <Group GroupId="ef19d" GraphId="fdc37" Style="Complex"/> <Group GroupId="ae1e0" GraphId="a15fc" Style="Complex"/> <Group GroupId="eed7b" GraphId="bcc90" Style="Complex"/> <InfoBox CenterX="0.0" CenterY="0.0"/> <Biopax> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="c7d"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">25080474</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Fat cells gain new identities.</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sci Transl Med</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2014</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nascimento EB</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Boon MR</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">van Marken Lichtenbelt WD</bp:AUTHORS> </bp:PublicationXref> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="f7c"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string"/> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Handbook of Obesity (3rd edition)</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CRC Press</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2014</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">George A. Bray</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Claude Bouchard</bp:AUTHORS> </bp:PublicationXref> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"><bp:TERM>regulatory pathway</bp:TERM><bp:ID>PW:0000004</bp:ID><bp:Ontology>Pathway Ontology</bp:Ontology></bp:openControlledVocabulary></Biopax> </Pathway>

Return to Differentiation of white and brown adipocyte (Bos taurus).