Sphingolipid metabolism: integrated pathway (Homo sapiens)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Sphingolipid metabolism: integrated pathway" Version="20180908" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">This pathway is inspired by the Lipidmaps&gt;Sphingolipids pathway (all chain lengths) [https://lipidmaps.org/resources/pathways/vanted.php]. Sphingolipids are a class of lipids, which act as signal transduction and cell recognition molecules. This pathway shows all different tail lengths and their conversions into specific products. All products are annotated with lipid-specific identifiers (if available). The general overview pathway can be found [https://www.wikipathways.org/index.php/Pathway:WP4344 here].</Comment> <Comment Source="WikiPathways-description">Overview PW</Comment> <Comment Source="HomologyMapper">This pathway was inferred from Mus musculus pathway [WP4690_107209.gpml] with a 95.0% conversion rate.</Comment> <Comment Source="WikiPathways-description">New PW, homology converted</Comment> <BiopaxRef>f6b</BiopaxRef> <Graphics BoardWidth="2037.649949454143" BoardHeight="1055.4527808526036"/> <DataNode TextLabel="ATP" GraphId="d1d97" Type="Metabolite"> <Graphics CenterX="1350.991240427962" CenterY="55.50341649521158" Width="59.73684210526337" Height="25.0" ZOrder="32975" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:30616"/> </DataNode> <DataNode TextLabel="3-keto-sphinganine" GraphId="e703c" Type="Metabolite"> <BiopaxRef>b6c</BiopaxRef> <Graphics CenterX="553.1340776182458" CenterY="109.883695693383" Width="117.50000000000003" Height="34.5" ZOrder="32976" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP01020002"/> </DataNode> <DataNode TextLabel="Ppap2a" GraphId="ccdfa" Type="GeneProduct" GroupRef="c9cc7"> <Comment Source="HomologyMapper">No homologues found for original id L:19012</Comment> <Graphics CenterX="1200.5153823208593" CenterY="825.6686739609008" Width="63.0" Height="23.5" ZOrder="32977" FontSize="12" Valign="Middle"/> <Xref Database="Uniprot-TrEMBL" ID="O14494"/> </DataNode> <DataNode TextLabel="CERK" GraphId="b872c" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:223753</Comment> <Graphics CenterX="187.16039511425146" CenterY="413.1433147740269" Width="82.5" Height="20.0" ZOrder="32978" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100422"/> </DataNode> <DataNode TextLabel="SGPP1" GraphId="a0e59" Type="Protein" GroupRef="aa54a"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9JI99</Comment> <Graphics CenterX="1435.934453346066" CenterY="153.46532678012312" Width="90.0" Height="25.0" ZOrder="32979" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000126821"/> </DataNode> <DataNode TextLabel="ASAH1" GraphId="d262d" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9WV54</Comment> <Graphics CenterX="956.8933371294632" CenterY="747.3467641929162" Width="73.13642756680707" Height="25.0" ZOrder="32980" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000104763"/> </DataNode> <DataNode TextLabel="Palmitoyl-CoA" GraphId="e79a6" Type="Metabolite"> <Comment>aka CoA(16:0)</Comment> <BiopaxRef>b6c</BiopaxRef> <Graphics CenterX="296.22413973004495" CenterY="109.88369569338299" Width="110.5" Height="34.50000000000001" ZOrder="32981" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMFA07050360"/> </DataNode> <DataNode TextLabel="SGMS1" GraphId="fb59f" Type="Protein" GroupRef="dbad2"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208449</Comment> <Graphics CenterX="386.8234599417437" CenterY="306.26962301924175" Width="79.5" Height="21.5" ZOrder="32982" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000198964"/> </DataNode> <DataNode TextLabel="SPHK2" GraphId="ec90a" Type="Protein" GroupRef="e9c94"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9JIA7</Comment> <Graphics CenterX="821.3852126989093" CenterY="833.9689665697512" Width="90.0" Height="20.791338582677554" ZOrder="32983" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000063176"/> </DataNode> <DataNode TextLabel="SGPL1" GraphId="aacd8" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20397</Comment> <Graphics CenterX="815.9707269059452" CenterY="948.1721901353038" Width="90.0" Height="25.0" ZOrder="32984" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000166224"/> </DataNode> <DataNode TextLabel="UGCG" GraphId="d041a" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22234</Comment> <Graphics CenterX="187.16039511425143" CenterY="491.9951464185663" Width="82.49999999999999" Height="23.880597014925364" ZOrder="32985" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000148154"/> </DataNode> <DataNode TextLabel="Serine" GraphId="bbf76" Type="Metabolite"> <BiopaxRef>b6c</BiopaxRef> <Graphics CenterX="298.0227008811241" CenterY="154.93968523139125" Width="110.50000000000003" Height="34.50000000000001" ZOrder="32986" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="PubChem-compound" ID="5951"/> </DataNode> <DataNode TextLabel="Hexadecanal" GraphId="d8f79" Type="Metabolite"> <Graphics CenterX="1892.7439312049723" CenterY="109.883695693383" Width="90.00000000000001" Height="34.50000000000001" ZOrder="32987" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMFA06000088"/> </DataNode> <DataNode TextLabel="SPTLC1" GraphId="cc2ed" Type="Protein" GroupRef="ee7e5"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:268656</Comment> <Graphics CenterX="422.5622298080355" CenterY="34.46139871900121" Width="112.5" Height="26.333333333333705" ZOrder="32988" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000090054"/> </DataNode> <DataNode TextLabel="SPHK1" GraphId="a14a8" Type="Protein" GroupRef="e9c94"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q8CI15</Comment> <Graphics CenterX="821.3852126989093" CenterY="812.9440321865493" Width="90.0" Height="21.25853018372678" ZOrder="32989" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000176170"/> </DataNode> <DataNode TextLabel="DEGS1" GraphId="cf753" Type="Protein" GroupRef="d2b68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13244</Comment> <Graphics CenterX="473.12736127419385" CenterY="484.9259051582969" Width="62.5" Height="18.5" ZOrder="32990" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143753"/> </DataNode> <DataNode TextLabel="KDSR" GraphId="cccac" Type="Protein"> <Comment>AKA Fvt1</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q6GV12</Comment> <Graphics CenterX="768.1822879193946" CenterY="50.7746124221007" Width="102.5" Height="23.833333333333307" ZOrder="32991" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000119537"/> </DataNode> <DataNode TextLabel="SPTLC2" GraphId="db18a" Type="Protein" GroupRef="ee7e5"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:P97363</Comment> <Graphics CenterX="422.5622298080355" CenterY="60.21139871900073" Width="112.75" Height="25.166666666665265" ZOrder="32992" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100596"/> </DataNode> <DataNode TextLabel="Ethanolamine-phosphate" GraphId="ab939" Type="Metabolite"> <Graphics CenterX="1892.7439312049723" CenterY="163.80135484977964" Width="151.00000000000003" Height="34.50000000000001" ZOrder="32993" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="PubChem-compound" ID="1015"/> </DataNode> <DataNode TextLabel="H2O" GraphId="dd604" Type="Metabolite"> <Graphics CenterX="1350.991240427962" CenterY="141.6941028548902" Width="54.4736842105263" Height="25.0" ZOrder="32994" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:15377"/> </DataNode> <DataNode TextLabel="Sphingosine" GraphId="f6010" Type="Metabolite"> <Graphics CenterX="1079.4057055053474" CenterY="790.9868877443047" Width="160.66666666666657" Height="24.999999999999968" ZOrder="32995" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP01010001"/> </DataNode> <DataNode TextLabel="Sphinganine" GraphId="a0809" Type="Metabolite"> <BiopaxRef>b6c</BiopaxRef> <Graphics CenterX="1079.4057055053477" CenterY="109.88369569338299" Width="160.6666666666666" Height="34.50000000000001" ZOrder="32996" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP01020001"/> </DataNode> <DataNode TextLabel="Sphinganine-1-phosphate" GraphId="eb7f3" Type="Metabolite"> <Graphics CenterX="1591.0492762726656" CenterY="109.88369569338299" Width="160.6666666666666" Height="34.50000000000001" ZOrder="32997" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP01050002"/> </DataNode> <DataNode TextLabel="CERS4" GraphId="b8d4a" Type="Protein" GroupRef="f1b02"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67260</Comment> <Graphics CenterX="502.2887311976484" CenterY="315.16408661167435" Width="52.95614268548025" Height="25.0" ZOrder="32998" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000090661"/> </DataNode> <DataNode TextLabel="CERS5" GraphId="d18e8" Type="Protein" GroupRef="ec55e"> <Comment>AKA Lass5</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9D6K9</Comment> <BiopaxRef>f88</BiopaxRef> <BiopaxRef>d60</BiopaxRef> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="222.61925989035606" CenterY="291.430276511951" Width="52.95614268548025" Height="25.0" ZOrder="32999" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000139624"/> </DataNode> <DataNode TextLabel="CERS6" GraphId="f5d48" Type="Protein" GroupRef="ec55e"> <Comment>AKA Lass6</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q8C172</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="222.61925989035606" CenterY="316.4302765119511" Width="52.95614268548025" Height="25.0" ZOrder="33000" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172292"/> </DataNode> <DataNode TextLabel="C16 CerP" GraphId="e59bc" Type="Metabolite"> <Graphics CenterX="175.44078746891347" CenterY="560.5792201459867" Width="87.99702178113748" Height="28.500000000000032" ZOrder="33001" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C16DH CerP" GraphId="cfdee" Type="Metabolite"> <Graphics CenterX="175.44078746891347" CenterY="365.60443588262086" Width="87.99702178113748" Height="28.500000000000007" ZOrder="33002" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C16 SM" GraphId="f4bbf" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="388.6375173990299" CenterY="560.5792201459867" Width="80.1485915924447" Height="28.5" ZOrder="33003" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010003"/> </DataNode> <DataNode TextLabel="C16 GlcCer" GraphId="a5ca8" Type="Metabolite"> <Graphics CenterX="175.44078746891347" CenterY="652.288477131028" Width="87.99702178113748" Height="28.499999999999982" ZOrder="33004" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA03"/> </DataNode> <DataNode TextLabel="C16DH SM" GraphId="e0930" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="387.3587450205132" CenterY="365.6044358826209" Width="87.26368110650976" Height="28.5" ZOrder="33005" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010004"/> </DataNode> <DataNode TextLabel="C16DH GlcCer" GraphId="baf73" Type="Metabolite"> <Graphics CenterX="175.44078746891347" CenterY="463.6070161634906" Width="87.99702178113742" Height="28.5" ZOrder="33006" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA04"/> </DataNode> <DataNode TextLabel="C16 GalCer" GraphId="a9aa0" Type="Metabolite"> <Graphics CenterX="388.6375173990299" CenterY="652.288477131028" Width="91.8771884833225" Height="28.5" ZOrder="33007" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C16DH GalCer" GraphId="ec374" Type="Metabolite"> <Graphics CenterX="386.6956768580827" CenterY="463.6070161634906" Width="108.50122940403917" Height="28.5" ZOrder="33008" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="SMPD1" GraphId="ee612" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20597</Comment> <Graphics CenterX="386.8234599417437" CenterY="403.95402353938147" Width="79.5" Height="21.500000000000018" ZOrder="33009" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000166311"/> </DataNode> <DataNode TextLabel="DEGS2" GraphId="dbbd0" Type="Protein" GroupRef="d2b68"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:70059</Comment> <Graphics CenterX="473.12736127419385" CenterY="503.42590515829676" Width="62.5" Height="18.5" ZOrder="33010" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000168350"/> </DataNode> <DataNode TextLabel="SGMS2" GraphId="ee229" Type="Protein" GroupRef="dbad2"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74442</Comment> <Graphics CenterX="386.8234599417437" CenterY="327.2696230192413" Width="79.5" Height="21.500000000000018" ZOrder="33011" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000164023"/> </DataNode> <DataNode TextLabel="Sphingosine-1-phosphate" GraphId="f2084" Type="Metabolite"> <Graphics CenterX="1079.4057055053477" CenterY="894.6619932295374" Width="160.66666666666663" Height="31.833333333333485" ZOrder="33012" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP01050001"/> </DataNode> <DataNode TextLabel="1-Hexadecenal" GraphId="cc77f" Type="Metabolite"> <Graphics CenterX="1079.4057055053477" CenterY="1012.9527808526035" Width="90.0" Height="25.0" ZOrder="33013" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMFA06000088"/> </DataNode> <DataNode TextLabel="PLPP3" GraphId="cdd52" Type="Protein" GroupRef="c9cc7"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67916</Comment> <Graphics CenterX="1200.5153823208593" CenterY="848.4186739609008" Width="63.0" Height="23.5" ZOrder="33014" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000162407"/> </DataNode> <DataNode TextLabel="Ppap2c" GraphId="c70d1" Type="Protein" GroupRef="c9cc7"> <Graphics CenterX="1200.5153823208593" CenterY="871.9186739609008" Width="63.0" Height="23.5" ZOrder="33015" FontSize="12" Valign="Middle"/> <Xref Database="Uniprot-TrEMBL" ID="O43688"/> </DataNode> <DataNode TextLabel="UGT8" GraphId="dbb07" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22239</Comment> <Graphics CenterX="386.8234599417437" CenterY="430.5749496739821" Width="79.5" Height="20.00000000000001" ZOrder="33016" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000174607"/> </DataNode> <DataNode TextLabel="CoA(16:0)" GraphId="be53c" Type="Metabolite"> <Graphics CenterX="335.6102448733302" CenterY="234.98962055345515" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33017" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMFA07050360"/> </DataNode> <DataNode TextLabel="CoA(18:0)" GraphId="fadb3" Type="Metabolite"> <Graphics CenterX="504.6719158799568" CenterY="234.98962055345518" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33018" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:15541"/> </DataNode> <DataNode TextLabel="CoA(20:0)" GraphId="dedfd" Type="Metabolite"> <Graphics CenterX="760.9769711562283" CenterY="234.98962055345518" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33019" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:15527"/> </DataNode> <DataNode TextLabel="CoA(22:0)" GraphId="afb32" Type="Metabolite"> <Comment>AKA "Coenzyme A, S-​docosanoate"</Comment> <Graphics CenterX="988.7977050208907" CenterY="234.98962055345518" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33020" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="CAS" ID="24330-89-0"/> </DataNode> <DataNode TextLabel="CoA(24:0)" GraphId="ed529" Type="Metabolite"> <Comment>AKA "Coenzyme A, S-​(tetracosanoate)​"</Comment> <Graphics CenterX="1327.535786831392" CenterY="258.9870830618465" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33021" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="CAS" ID="24305-30-4"/> </DataNode> <DataNode TextLabel="CoA(24:1)" GraphId="e7f29" Type="Metabolite"> <Comment>AKA "Coenzyme A, S-​(15Z)​-​15-​tetracosenoate"</Comment> <Graphics CenterX="1179.069160048823" CenterY="271.68483696179567" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33022" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="CAS" ID="88362-35-0"/> </DataNode> <DataNode TextLabel="C16DH-Cer" GraphId="dd764" Type="Metabolite"> <Graphics CenterX="278.3112458818351" CenterY="411.94977377758704" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33023" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02020001"/> </DataNode> <DataNode TextLabel="CERS1" GraphId="c1570" Type="Protein" GroupRef="f1b02"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:P27545</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="502.2887311976484" CenterY="290.1640866116744" Width="52.95614268548025" Height="25.0" ZOrder="33032" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000223802"/> </DataNode> <DataNode TextLabel="CERS4" GraphId="f4edd" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67260</Comment> <Graphics CenterX="753.6477063042356" CenterY="264.4445502003541" Width="52.95614268548025" Height="25.0" ZOrder="33035" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000090661"/> </DataNode> <DataNode TextLabel="CERS2" GraphId="f9b8e" Type="Protein"> <Comment>Original LipidMaps annotation</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:76893</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="1426.82320646663" CenterY="272.014526094128" Width="52.956142685480245" Height="25.0" ZOrder="33038" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143418"/> </DataNode> <DataNode TextLabel="CoA(26:0)" GraphId="d0eaa" Type="Metabolite"> <Comment>AKA "Coenzyme A, S-​hexacosanoate"</Comment> <Graphics CenterX="1761.8842624462422" CenterY="234.36242815638042" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33040" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="CAS" ID="99313-57-2"/> </DataNode> <DataNode TextLabel="CoA(26:1)" GraphId="ad81f" Type="Metabolite"> <Graphics CenterX="1599.1361618332037" CenterY="234.6524038381416" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33041" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMFA07050099"/> </DataNode> <DataNode TextLabel="CERS3" GraphId="e1c24" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q1A3B0</Comment> <Graphics CenterX="1736.4452399490672" CenterY="279.36137551785345" Width="52.956142685480245" Height="25.0" ZOrder="33046" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000154227"/> </DataNode> <DataNode TextLabel="ADP" GraphId="e873a" Type="Metabolite"> <Graphics CenterX="1534.8549608001194" CenterY="54.02582464985991" Width="59.73684210526337" Height="25.0" ZOrder="33048" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:456216"/> </DataNode> <DataNode TextLabel="SGPP2" GraphId="e932e" Type="Protein" GroupRef="aa54a"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q810K3</Comment> <Graphics CenterX="1435.934453346066" CenterY="178.465326780123" Width="90.0" Height="25.0" ZOrder="33050" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000163082"/> </DataNode> <DataNode TextLabel="SPHK2" GraphId="cc11d" Type="Protein" GroupRef="a4b6e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9JIA7</Comment> <Graphics CenterX="1434.1349482547225" CenterY="51.712748196543" Width="90.0" Height="20.791338582677554" ZOrder="33052" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000063176"/> </DataNode> <DataNode TextLabel="SPHK1" GraphId="c27d1" Type="Protein" GroupRef="a4b6e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q8CI15</Comment> <Graphics CenterX="1434.1349482547225" CenterY="30.68781381334083" Width="90.0" Height="21.25853018372678" ZOrder="33053" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000176170"/> </DataNode> <DataNode TextLabel="SGPL1" GraphId="e9c81" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20397</Comment> <Graphics CenterX="1744.747123653181" CenterY="50.774612422100724" Width="90.0" Height="25.0" ZOrder="33054" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000166224"/> </DataNode> <DataNode TextLabel="CERS4" GraphId="e2f78" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67260</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="988.7977050208906" CenterY="264.4445502003541" Width="52.95614268548025" Height="25.0" ZOrder="33056" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000090661"/> </DataNode> <DataNode TextLabel="CERS2" GraphId="d657f" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:76893</Comment> <Graphics CenterX="1226.6520265706956" CenterY="310.41721582661927" Width="52.956142685480245" Height="25.0" ZOrder="33057" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143418"/> </DataNode> <DataNode TextLabel="CERS4" GraphId="c248e" Type="Protein"> <Comment>Protein found in literature (not in original LipidMapsPW)</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67260</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="1511.4738472926372" CenterY="253.29564396797352" Width="52.95614268548025" Height="25.0" ZOrder="33059" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000090661"/> </DataNode> <DataNode TextLabel="CoA(14:0)" GraphId="a265d" Type="Metabolite"> <Graphics CenterX="117.71825946285624" CenterY="215.79662535433326" Width="76.20140834040546" Height="25.000000000000004" ZOrder="33061" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C14DH-Ceramide" GraphId="c0d7e" Type="Metabolite"> <Graphics CenterX="61.87691807093058" CenterY="398.52209859990097" Width="108.2099509805688" Height="25.000000000000004" ZOrder="33062" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="CERS5" GraphId="c6b8d" Type="Protein" GroupRef="e2566"> <Comment>AKA Lass5</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9D6K9</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="123.33660132233057" CenterY="282.09031470412464" Width="52.95614268548025" Height="25.0" ZOrder="33063" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000139624"/> </DataNode> <DataNode TextLabel="CERS6" GraphId="bf01f" Type="Protein" GroupRef="e2566"> <Comment>AKA Lass6</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q8C172</Comment> <BiopaxRef>b4a</BiopaxRef> <Graphics CenterX="123.33660132233057" CenterY="307.09031470412475" Width="52.95614268548025" Height="25.0" ZOrder="33064" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172292"/> </DataNode> <DataNode TextLabel="C16 Cer" GraphId="ee093" Type="Metabolite"> <BiopaxRef>b6c</BiopaxRef> <Graphics CenterX="278.3112458818351" CenterY="598.3820013773427" Width="94.41650879417699" Height="25.28203305094405" ZOrder="33065" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02010004"/> </DataNode> <DataNode TextLabel="CERK" GraphId="e8f47" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:223753</Comment> <Graphics CenterX="187.16039511425146" CenterY="526.7238774338734" Width="82.49999999999999" Height="20.00000000000001" ZOrder="33066" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000100422"/> </DataNode> <DataNode TextLabel="UGCG" GraphId="c2756" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22234</Comment> <Graphics CenterX="187.16039511425143" CenterY="592.335155940161" Width="82.49999999999999" Height="23.880597014925364" ZOrder="33067" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000148154"/> </DataNode> <DataNode TextLabel="SMPD1" GraphId="b9085" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20597</Comment> <Graphics CenterX="386.8234599417437" CenterY="593.9992469608264" Width="79.5" Height="21.500000000000018" ZOrder="33068" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000166311"/> </DataNode> <DataNode TextLabel="SGMS1" GraphId="d62b9" Type="Protein" GroupRef="ad0f5"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208449</Comment> <Graphics CenterX="386.8234599417437" CenterY="513.2675589772562" Width="79.5" Height="21.500000000000018" ZOrder="33069" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000198964"/> </DataNode> <DataNode TextLabel="SGMS2" GraphId="c79e6" Type="Protein" GroupRef="ad0f5"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74442</Comment> <Graphics CenterX="386.8234599417437" CenterY="534.2675589772559" Width="79.5" Height="21.500000000000018" ZOrder="33070" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000164023"/> </DataNode> <DataNode TextLabel="UGT8" GraphId="d85dd" Type="Protein"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22239</Comment> <Graphics CenterX="386.8234599417437" CenterY="620.8818550448259" Width="79.5" Height="20.00000000000001" ZOrder="33071" FontSize="12" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000174607"/> </DataNode> <DataNode TextLabel="C18 CerP" GraphId="ab23f" Type="Metabolite"> <Graphics CenterX="504.67191587995677" CenterY="557.1844680718984" Width="87.99702178113748" Height="28.500000000000032" ZOrder="33073" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C18DH CerP" GraphId="ea9a6" Type="Metabolite"> <Graphics CenterX="504.67191587995677" CenterY="362.2096838085327" Width="87.99702178113748" Height="28.500000000000007" ZOrder="33074" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C18 SM" GraphId="ee08b" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="696.582722878482" CenterY="557.1844680718984" Width="80.1485915924447" Height="28.5" ZOrder="33075" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010001"/> </DataNode> <DataNode TextLabel="C18 GlcCer" GraphId="cd624" Type="Metabolite"> <Graphics CenterX="504.6719158799567" CenterY="631.8824772819072" Width="87.99702178113748" Height="28.499999999999982" ZOrder="33076" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA05"/> </DataNode> <DataNode TextLabel="C18DH SM" GraphId="c2e38" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="662.134986926012" CenterY="362.2096838085327" Width="87.26368110650976" Height="28.5" ZOrder="33077" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010020"/> </DataNode> <DataNode TextLabel="C18DH GlcCer" GraphId="e98fe" Type="Metabolite"> <Graphics CenterX="504.67191587995677" CenterY="453.68697860816246" Width="87.99702178113742" Height="28.5" ZOrder="33078" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA19"/> </DataNode> <DataNode TextLabel="C18 GalCer" GraphId="a518f" Type="Metabolite"> <Graphics CenterX="662.134986926012" CenterY="631.8824772819072" Width="91.8771884833225" Height="28.5" ZOrder="33079" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C18DH GalCer" GraphId="b4d89" Type="Metabolite"> <Graphics CenterX="662.134986926012" CenterY="453.6869786081625" Width="108.50122940403917" Height="28.5" ZOrder="33080" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C18DH-Cer" GraphId="e5f2b" Type="Metabolite"> <Graphics CenterX="586.2564513612868" CenterY="408.5550217034988" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33081" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02020008"/> </DataNode> <DataNode TextLabel="C18 Cer" GraphId="a223b" Type="Metabolite"> <Graphics CenterX="586.2564513612875" CenterY="594.9872493032599" Width="94.41650879417699" Height="25.28203305094405" ZOrder="33082" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02010006"/> </DataNode> <DataNode TextLabel="C20 CerP" GraphId="fe480" Type="Metabolite"> <Graphics CenterX="760.9769711562282" CenterY="516.196044110362" Width="87.99702178113748" Height="28.500000000000032" ZOrder="33093" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C20DH CerP" GraphId="d302f" Type="Metabolite"> <Graphics CenterX="760.9769711562283" CenterY="323.17858446076843" Width="87.99702178113748" Height="28.500000000000007" ZOrder="33094" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C20 SM" GraphId="f03df" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="891.6228051999727" CenterY="516.196044110362" Width="80.1485915924447" Height="28.5" ZOrder="33095" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010005"/> </DataNode> <DataNode TextLabel="C20 GlcCer" GraphId="d69bf" Type="Metabolite"> <Graphics CenterX="760.9769711562283" CenterY="603.5896329676987" Width="87.99702178113748" Height="28.499999999999982" ZOrder="33096" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA06"/> </DataNode> <DataNode TextLabel="C20DH SM" GraphId="e4386" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="894.8854479405926" CenterY="323.17858446076843" Width="87.26368110650976" Height="28.5" ZOrder="33097" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010021"/> </DataNode> <DataNode TextLabel="C20DH GlcCer" GraphId="acbd8" Type="Metabolite"> <Graphics CenterX="760.9769711562283" CenterY="420.0250067771768" Width="87.99702178113742" Height="28.5" ZOrder="33098" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA20"/> </DataNode> <DataNode TextLabel="C20 GalCer" GraphId="c65ae" Type="Metabolite"> <Graphics CenterX="893.2541265702828" CenterY="603.5896329676985" Width="91.8771884833225" Height="28.5" ZOrder="33099" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C20DH GalCer" GraphId="b4b09" Type="Metabolite"> <Graphics CenterX="894.8854479405926" CenterY="420.0250067771768" Width="108.50122940403917" Height="28.5" ZOrder="33100" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C20DH-Cer" GraphId="e8978" Type="Metabolite"> <Graphics CenterX="827.7880079026652" CenterY="374.89304987251313" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33101" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02020009"/> </DataNode> <DataNode TextLabel="C20 Cer" GraphId="ac886" Type="Metabolite"> <Graphics CenterX="827.788007902666" CenterY="561.3252774722775" Width="94.41650879417699" Height="25.28203305094405" ZOrder="33102" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02010007"/> </DataNode> <DataNode TextLabel="C22 CerP" GraphId="e4e6f" Type="Metabolite"> <Graphics CenterX="988.7977050208906" CenterY="486.6126420657736" Width="87.99702178113748" Height="28.500000000000032" ZOrder="33113" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C22DH CerP" GraphId="b25a5" Type="Metabolite"> <Graphics CenterX="988.7977050208905" CenterY="300.22074825871175" Width="87.99702178113748" Height="28.500000000000007" ZOrder="33114" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C22 SM" GraphId="b3f40" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="1142.7528038120327" CenterY="486.61264206577357" Width="80.1485915924447" Height="28.5" ZOrder="33115" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010006"/> </DataNode> <DataNode TextLabel="C22 GlcCer" GraphId="f1efe" Type="Metabolite"> <Graphics CenterX="988.7977050208906" CenterY="567.0057820360219" Width="87.99702178113748" Height="28.499999999999982" ZOrder="33116" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA07"/> </DataNode> <DataNode TextLabel="C22DH SM" GraphId="b8d18" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="1142.7528038120329" CenterY="300.2207482587118" Width="87.26368110650976" Height="28.5" ZOrder="33117" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010022"/> </DataNode> <DataNode TextLabel="C22DH GlcCer" GraphId="a84b1" Type="Metabolite"> <Graphics CenterX="990.4290263912006" CenterY="383.4411558455" Width="87.99702178113742" Height="28.5" ZOrder="33118" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA21"/> </DataNode> <DataNode TextLabel="C22 GalCer" GraphId="bae01" Type="Metabolite"> <Graphics CenterX="1142.7528038120329" CenterY="567.0057820360219" Width="91.8771884833225" Height="28.5" ZOrder="33119" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C22DH GalCer" GraphId="aaba9" Type="Metabolite"> <Graphics CenterX="1142.7528038120327" CenterY="383.4411558455" Width="108.50122940403917" Height="28.5" ZOrder="33120" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C22DH-Cer" GraphId="d12ab" Type="Metabolite"> <Graphics CenterX="1079.405705505347" CenterY="333.6688277111379" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33121" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02020010"/> </DataNode> <DataNode TextLabel="C22 Cer" GraphId="ec73f" Type="Metabolite"> <Graphics CenterX="1079.4057055053477" CenterY="524.7414265406007" Width="94.41650879417699" Height="25.28203305094405" ZOrder="33122" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02010008"/> </DataNode> <DataNode TextLabel="C24 CerP" GraphId="ae6a5" Type="Metabolite"> <Graphics CenterX="1378.4684878906855" CenterY="488.64924284549863" Width="87.99702178113748" Height="28.500000000000032" ZOrder="33134" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C24DH CerP" GraphId="e50cb" Type="Metabolite"> <Graphics CenterX="1378.4684878906855" CenterY="300.5257473068355" Width="87.99702178113748" Height="28.500000000000007" ZOrder="33135" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C24 SM" GraphId="c23d6" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="1532.4235866818276" CenterY="488.64924284549784" Width="80.1485915924447" Height="28.5" ZOrder="33136" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010008"/> </DataNode> <DataNode TextLabel="C24 GlcCer" GraphId="bb0cf" Type="Metabolite"> <Graphics CenterX="1378.4684878906855" CenterY="569.0423828157453" Width="87.99702178113748" Height="28.499999999999982" ZOrder="33137" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA09"/> </DataNode> <DataNode TextLabel="C24DH SM" GraphId="a0374" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="1546.626298108555" CenterY="293.4243915934712" Width="87.26368110650976" Height="28.5" ZOrder="33138" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010024"/> </DataNode> <DataNode TextLabel="C24DH GlcCer" GraphId="ac9b7" Type="Metabolite"> <Graphics CenterX="1380.0998092609957" CenterY="385.47775662522474" Width="87.99702178113742" Height="28.5" ZOrder="33139" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA23"/> </DataNode> <DataNode TextLabel="C24 GalCer" GraphId="f193c" Type="Metabolite"> <Graphics CenterX="1532.4235866818278" CenterY="569.0423828157456" Width="91.8771884833225" Height="28.5" ZOrder="33140" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C24DH GalCer" GraphId="f97e3" Type="Metabolite"> <Graphics CenterX="1532.4235866818276" CenterY="385.47775662522474" Width="108.50122940403917" Height="28.5" ZOrder="33141" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C24DH-Cer" GraphId="ba745" Type="Metabolite"> <Graphics CenterX="1457.2724553687324" CenterY="335.7054284908628" Width="94.90557318028613" Height="25.000000000000004" ZOrder="33142" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02020012"/> </DataNode> <DataNode TextLabel="C24 Cer" GraphId="b238d" Type="Metabolite"> <Graphics CenterX="1457.2724553687333" CenterY="526.7780273203268" Width="94.41650879417699" Height="25.28203305094405" ZOrder="33143" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP02010012"/> </DataNode> <DataNode TextLabel="C24:1 CerP" GraphId="e703b" Type="Metabolite"> <Graphics CenterX="1184.780955979741" CenterY="530.7687924780644" Width="87.99702178113748" Height="28.500000000000032" ZOrder="33154" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C24:1DH CerP" GraphId="c44f9" Type="Metabolite"> <Graphics CenterX="1184.7809559797408" CenterY="342.6452969394011" Width="87.99702178113748" Height="28.500000000000007" ZOrder="33155" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID=""/> </DataNode> <DataNode TextLabel="C24:1 SM" GraphId="da8d8" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="1338.7360547708834" CenterY="530.768792478064" Width="80.1485915924447" Height="28.5" ZOrder="33156" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010007"/> </DataNode> <DataNode TextLabel="C24:1 GlcCer" GraphId="ca0d7" Type="Metabolite"> <Graphics CenterX="1184.780955979741" CenterY="611.1619324483124" Width="87.99702178113748" Height="28.499999999999982" ZOrder="33157" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP0501AA08"/> </DataNode> <DataNode TextLabel="C24:1DH SM" GraphId="d0c7d" Type="Metabolite"> <Comment>SM = sphingomyelin</Comment> <Graphics CenterX="1338.7360547708836" CenterY="342.64529693940113" Width="87.26368110650976" Height="28.5" ZOrder="33158" FontSize="12" Valign="Middle" Color="0000ff"/> <Xref Database="LIPID MAPS" ID="LMSP03010023"/> </DataNode> <DataNode TextLabel="C24:1DH GlcCer" GraphId="ef3a5" Type="Metabolite"> <Graphics CenterX="1186.412277350051" 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