Inhibitors of metabolism in melanoma therapy (Homo sapiens)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Inhibitors of metabolism in melanoma therapy" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO- and H+. The free energy released in this process is used to form the ATP and NADH. Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids. Description adapted from [Wikipedia](http://www.wikipedia.org). Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP534).</Comment> <Comment Source="GenMAPP notes"></Comment> <Comment Source="GenMAPP remarks"></Comment> <Comment Source="WikiPathways-category">Metabolic Process</Comment> <Comment Source="WikiPathways-description">draft</Comment> <BiopaxRef>f6a</BiopaxRef> <Graphics BoardWidth="1238.3333333333346" BoardHeight="1132.6666666666667" /> <DataNode TextLabel="OPi" GraphId="a0b44" Type="Metabolite" GroupRef="d37a5"> <Graphics CenterX="700.0" CenterY="1056.0" Width="70.0" Height="20.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="009999" /> <Xref Database="PubChem-compound" ID="86711931" /> </DataNode> <DataNode TextLabel="FK866" GraphId="a30a7" Type="Metabolite" GroupRef="ceb45"> <BiopaxRef>ba3</BiopaxRef> <Graphics CenterX="87.75" CenterY="678.25" Width="70.0" Height="20.0" ZOrder="32768" FontSize="12" Valign="Middle" 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