Phase I biotransformations, non-P450 (Bos taurus)

From WikiPathways

You do not have permission to edit pages, for the following reasons:

• You do not have permission to edit pages in the Pathway namespace.
• You are not allowed to execute the action you have requested.

You can view and copy the source of this page:

<?xml version="1.0" encoding="ISO-8859-1"?> <Pathway xmlns="http://genmapp.org/GPML/2008a" Name="Phase I, non P450" Version="20080228" Organism="Bos taurus" Last-Modified="7/29/2009"> <Comment Source="WikiPathways-description">This pathway lists several phase 1 biotransformations and their related enzymes. '''NOTE:''' This pathway is incomplete, reduction and oxidation enzymes are missing</Comment> <Comment Source="WikiPathways-category">Metabolic Process</Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP136&amp;oldid=29886 WP136(r29886)] with a 87% conversion rate.</Comment> <BiopaxRef>b69</BiopaxRef> <Graphics BoardWidth="10081.5" BoardHeight="6369.0" WindowWidth="18000.0" WindowHeight="12000.0"/> <DataNode TextLabel="CES1" Type="GeneProduct" GraphId="f26" GroupRef="d23ac" BackpageHead=""> <Graphics Color="000000" CenterX="4230.0" CenterY="1410.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="ESTD_BOVIN" Type="GeneProduct" GraphId="b38" GroupRef="d23ac" BackpageHead="ESTD_BOVIN"> <Graphics Color="000000" CenterX="4230.0" CenterY="1710.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000003415"/> </DataNode> <DataNode TextLabel="IPI00825242.3" Type="GeneProduct" GraphId="ac5" GroupRef="d23ac" BackpageHead="IPI00825242.3"> <Graphics Color="000000" CenterX="4230.0" CenterY="2010.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000011164"/> </DataNode> <DataNode TextLabel="NP_001029432.1" Type="GeneProduct" GraphId="dd4" GroupRef="d23ac" BackpageHead="NP_001029432.1"> <Graphics Color="000000" CenterX="4230.0" CenterY="2595.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000005093"/> </DataNode> <DataNode TextLabel="NP_001096793.1" Type="GeneProduct" GraphId="b6f" GroupRef="d23ac" BackpageHead="NP_001096793.1"> <Graphics Color="000000" CenterX="4230.0" CenterY="2310.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000003636"/> </DataNode> <DataNode TextLabel="NP_001039734.1" Type="GeneProduct" GraphId="ff0" GroupRef="ee236" BackpageHead="NP_001039734.1"> <Graphics Color="000000" CenterX="3975.0" CenterY="4920.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000015654"/> </DataNode> <DataNode TextLabel="PON2_BOVIN" Type="GeneProduct" GraphId="dfd" GroupRef="ee236" BackpageHead="PON2_BOVIN"> <Graphics Color="000000" CenterX="3975.0" CenterY="5220.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000008361"/> </DataNode> <DataNode TextLabel="NP_001068947.1" Type="GeneProduct" GraphId="b76" GroupRef="ee236" BackpageHead="NP_001068947.1"> <Graphics Color="000000" CenterX="3975.0" CenterY="5520.0" Width="1200.0" Height="300.0" ZOrder="32768"/> <Xref Database="Ensembl Cow" ID="ENSBTAG00000034645"/> </DataNode> <DataNode TextLabel="amides" Type="Metabolite" GraphId="bc7f3" GroupRef="f9ad7"> <Graphics Color="0000ff" CenterX="7170.0" CenterY="3120.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="ChEBI" ID="32988"/> </DataNode> <DataNode TextLabel="carboxylic acid esters" Type="Metabolite" GraphId="c109a" GroupRef="cff8d"> <Graphics Color="0000ff" CenterX="7170.0" CenterY="2760.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="thio esters" Type="Metabolite" GraphId="b198c" GroupRef="bb086"> <Graphics Color="0000ff" CenterX="7170.0" CenterY="3480.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Phosphoric acid esters" Type="Metabolite" GraphId="db710" GroupRef="cd78c"> <Graphics Color="0000ff" CenterX="7170.0" CenterY="4365.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="thio esters" Type="Metabolite" GraphId="a1626" GroupRef="b9ae8"> <Graphics Color="0000ff" CenterX="1575.0" CenterY="3495.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Phosphoric acid esters" Type="Metabolite" GraphId="a1e36"> <Graphics Color="0000ff" CenterX="1575.0" CenterY="4365.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="carboxylic acid esters" Type="Metabolite" GraphId="b758e" GroupRef="b9ae8"> <Graphics Color="0000ff" CenterX="1575.0" CenterY="2775.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="amides" Type="Metabolite" GraphId="e744e" GroupRef="b9ae8"> <Graphics Color="0000ff" CenterX="1575.0" CenterY="3135.0" Width="1935.0" Height="300.0" ZOrder="32768"/> <Xref Database="ChEBI" ID="32988"/> </DataNode> <Line Style="Solid" GraphId="db646"> <Graphics ZOrder="12288" Color="000000"> <Point x="3075.0926897531936" y="3119.990306829646" GraphRef="cae49" relX="1.0" relY="0.0"/> <Point x="5962.5" y="3105.0" GraphRef="b0e4c" relX="-1.0" relY="0.0" ArrowHead="Arrow"/> <Anchor position="0.4" Shape="None" GraphId="c961d"/> </Graphics> </Line> <Line Style="Solid" GraphId="af048"> <Graphics ZOrder="12288" Color="000000"> <Point x="2542.5" y="4365.0" GraphRef="a1e36" relX="1.0" relY="0.0"/> <Point x="6082.5" y="4365.0" GraphRef="c28bd" relX="-1.0" relY="0.0" ArrowHead="Arrow"/> <Anchor position="0.4" Shape="None" GraphId="ca3c4"/> </Graphics> </Line> <Line Style="Solid" GraphId="ae21f"> <Graphics ZOrder="12288" Color="000000"> <Point x="3975.0" y="4650.0" GraphRef="aa661" relX="0.0" relY="-1.0"/> <Point x="3958.5" y="4365.0" GraphRef="ca3c4" relX="0.0" relY="0.0" ArrowHead="mim-stimulation"/> </Graphics> </Line> <Line Style="Solid" GraphId="d1dd6"> <Graphics ZOrder="12288" Color="000000"> <Point x="4230.0" y="2865.0" GraphRef="ab569" relX="0.0" relY="1.0"/> <Point x="4230.055613851916" y="3113.9941840977876" GraphRef="c961d" relX="0.0" relY="0.0" ArrowHead="mim-stimulation"/> </Graphics> </Line> <Label TextLabel="OH" GraphId="db7" GroupRef="cff8d"> <Graphics FontSize="150" Color="00ccff" CenterX="8325.0" CenterY="2730.0" Width="1200.0" Height="300.0" ZOrder="28672"/> </Label> <Label TextLabel="OH" GraphId="e68" GroupRef="f9ad7"> <Graphics FontSize="150" Color="00ccff" CenterX="8325.0" CenterY="3120.0" Width="1200.0" Height="300.0" ZOrder="28672"/> </Label> <Label TextLabel="OH" GraphId="e3d" GroupRef="bb086"> <Graphics FontSize="150" Color="00ccff" CenterX="8325.0" CenterY="3480.0" Width="1200.0" Height="300.0" ZOrder="28672"/> </Label> <Label TextLabel="Hydrolysis" GraphId="f6a"> <Graphics FontWeight="Bold" FontSize="150" Color="000000" CenterX="4230.0" CenterY="735.0" Width="1200.0" Height="300.0" ZOrder="28672"/> </Label> <Label TextLabel="OH" GraphId="f1b" GroupRef="cd78c"> <Graphics FontSize="150" Color="00ccff" CenterX="8325.0" CenterY="4365.0" Width="1200.0" Height="300.0" ZOrder="28672"/> </Label> <Shape Type="Brace" Style="Solid" GraphId="f37" GroupRef="b9ae8"> <Graphics FillColor="Transparent" Color="000000" CenterX="2797.4741588314237" CenterY="3097.4903068296467" Width="1004.9741312762474" Height="315.09269300455264" ZOrder="16384" Rotation="1.5706526692754137"/> </Shape> <Group GroupId="b9ae8" GraphId="cae49" TextLabel="new group"/> <Group GroupId="cff8d" GraphId="a21b3" TextLabel="new group" GroupRef="a3c4f"/> <Group GroupId="f9ad7" GraphId="ac2ba" TextLabel="new group" GroupRef="a3c4f"/> <Group GroupId="bb086" GraphId="e0819" TextLabel="new group" GroupRef="a3c4f"/> <Group GroupId="cd78c" GraphId="c28bd" TextLabel="new group"/> <Group GroupId="a3c4f" GraphId="b0e4c" TextLabel="new group"/> <Group GroupId="d23ac" GraphId="ab569" TextLabel="new group"/> <Group GroupId="ee236" GraphId="aa661" TextLabel="new group"/> <InfoBox CenterX="0.0" CenterY="0.0"/> <Biopax> <bp:PublicationXRef xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bp="http://www.biopax.org/release/biopax-level2.owl#" rdf:id="b69"> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Casarett &amp;amp; Doull's Essentials of Toxicology</bp:TITLE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2003</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Klaassen, C.D.</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Watkins III, J.B.</bp:AUTHORS> </bp:PublicationXRef> </Biopax> </Pathway>

• Template:AuthorInfo
• Template:CheckAvailable (protected)
• Template:Help:LiteratureReferences (protected)
• Template:PathwayPage:History
• Template:PathwayPage:Xrefs

Return to Phase I biotransformations, non-P450 (Bos taurus).