GPCRs, class B secretin-like (Gallus gallus)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://genmapp.org/GPML/2008a" Name="GPCRs, Class B Secretin-like" Organism="Gallus gallus" License="CC BY 2.0"> <Comment Source="GenMAPP notes">This MAPP was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.</Comment> <Comment Source="WikiPathways-category">Molecular Function</Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP334&amp;amp;oldid=21381 WP334(r21381)] with a 62% conversion rate.</Comment> <Graphics BoardWidth="5632.0" BoardHeight="12177.0" WindowWidth="8587.0" WindowHeight="12914.0"/> <DataNode TextLabel="CALCR" Type="GeneProduct" BackpageHead="CALCR" GraphId="ca0" GroupRef="f02df"> <Graphics Color="000000" CenterX="1500.0" CenterY="2500.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="428425"/> </DataNode> <DataNode TextLabel="CALCRL" Type="GeneProduct" BackpageHead="CALCRL" GraphId="fc0" GroupRef="f02df"> <Graphics Color="000000" CenterX="1500.0" CenterY="2800.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="423990"/> </DataNode> <DataNode TextLabel="CRHR1" Type="GeneProduct" BackpageHead="CRHR1" GraphId="db4" GroupRef="b4223"> <Graphics Color="000000" CenterX="1500.0" CenterY="3400.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="374218"/> </DataNode> <DataNode TextLabel="CRHR2" Type="GeneProduct" BackpageHead="CRHR2" GraphId="e1e" GroupRef="b4223"> <Graphics Color="000000" CenterX="1500.0" CenterY="3700.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="395105"/> </DataNode> <DataNode TextLabel="GIPR" Type="GeneProduct" GraphId="c52"> <Graphics Color="000000" CenterX="1500.0" CenterY="4300.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="GLP2R" Type="GeneProduct" BackpageHead="GLP2R" GraphId="f3f" GroupRef="a9b0a"> <Graphics Color="000000" CenterX="1500.0" CenterY="4900.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="427787"/> </DataNode> <DataNode TextLabel="GLP1R" Type="GeneProduct" BackpageHead="GLP1R" GraphId="f31" GroupRef="a9b0a"> <Graphics Color="000000" CenterX="1500.0" CenterY="5200.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="428573"/> </DataNode> <DataNode TextLabel="GCGR" Type="GeneProduct" GraphId="c13" GroupRef="a9b0a"> <Graphics Color="000000" CenterX="1500.0" CenterY="5500.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="GHRHR" Type="GeneProduct" BackpageHead="GHRHR" GraphId="cab"> <Graphics Color="000000" CenterX="1500.0" CenterY="6100.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="420385"/> </DataNode> <DataNode TextLabel="PTHR2" Type="GeneProduct" GraphId="a6d" GroupRef="a60b5"> <Graphics Color="000000" CenterX="1500.0" CenterY="6750.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PTH1R" Type="GeneProduct" BackpageHead="PTH1R" GraphId="ac8" GroupRef="a60b5"> <Graphics Color="000000" CenterX="1500.0" CenterY="7050.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="420401"/> </DataNode> <DataNode TextLabel="ADCYAP1R1" Type="GeneProduct" BackpageHead="ADCYAP1R1" GraphId="f79"> <Graphics Color="000000" CenterX="1500.0" CenterY="7650.0" Width="1300.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="420386"/> </DataNode> <DataNode TextLabel="SCTR" Type="GeneProduct" BackpageHead="SCTR" GraphId="dd5"> <Graphics Color="000000" CenterX="1500.0" CenterY="8250.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="770943"/> </DataNode> <DataNode TextLabel="VIPR1" Type="GeneProduct" BackpageHead="VIPR1" GraphId="e74" GroupRef="ec598"> <Graphics Color="000000" CenterX="1500.0" CenterY="8850.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="395329"/> </DataNode> <DataNode TextLabel="VIPR2" Type="GeneProduct" BackpageHead="VIPR2" GraphId="f83" GroupRef="ec598"> <Graphics Color="000000" CenterX="1500.0" CenterY="9150.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="420453"/> </DataNode> <DataNode TextLabel="CD97" Type="GeneProduct" GraphId="c09" GroupRef="c601b"> <Graphics Color="000000" CenterX="1500.0" CenterY="9900.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="EMR1" Type="GeneProduct" GraphId="c5e" GroupRef="c601b"> <Graphics Color="000000" CenterX="1500.0" CenterY="10200.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="CD97" Type="GeneProduct" GraphId="e7c" GroupRef="c601b"> <Graphics Color="000000" CenterX="1500.0" CenterY="10500.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="EMR2" Type="GeneProduct" GraphId="f53" GroupRef="c601b"> <Graphics Color="000000" CenterX="1500.0" CenterY="10800.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="LPHN1" Type="GeneProduct" GraphId="eac" GroupRef="fd1b2"> <Graphics Color="000000" CenterX="3800.0" CenterY="2550.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="LPHN2" Type="GeneProduct" GraphId="eb2" GroupRef="fd1b2" BackpageHead="LPHN2"> <Graphics Color="000000" CenterX="3800.0" CenterY="2850.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="424545"/> </DataNode> <DataNode TextLabel="LPHN3" Type="GeneProduct" BackpageHead="LPHN3" GraphId="d0b" GroupRef="fd1b2"> <Graphics Color="000000" CenterX="3800.0" CenterY="3150.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="422616"/> </DataNode> <DataNode TextLabel="ELTD1" Type="GeneProduct" BackpageHead="ELTD1" GraphId="a0a" GroupRef="fd1b2"> <Graphics Color="000000" CenterX="3800.0" CenterY="3450.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="424546"/> </DataNode> <DataNode TextLabel="GPR64" Type="GeneProduct" BackpageHead="GPR64" GraphId="c23"> <Graphics Color="000000" CenterX="3800.0" CenterY="4150.0" Width="900.0" Height="300.0" ZOrder="32768"/> <Xref Database="Entrez Gene" ID="418611"/> </DataNode> <Label TextLabel="Calcitonin" GraphId="afa"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="2200.0" Width="815.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Corticotropin releasing factor" GraphId="a2f"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="3100.0" Width="2225.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Gastric inhibitory peptide" GraphId="e79"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="4000.0" Width="1925.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Glucagon" GraphId="ae6"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="4600.0" Width="785.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Growth hormone-releasing hormone" GraphId="ab3"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="5800.0" Width="2735.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Parathyroid hormone" GraphId="d62"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="6450.0" Width="1610.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="PACAP" GraphId="a7a"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="7350.0" Width="605.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Secretin" GraphId="a39"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="7950.0" Width="695.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Vasoactive intestinal polypeptide" GraphId="af9"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="8550.0" Width="2525.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Diuretic hormone&#10;EMR1" GraphId="f1b"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="1500.0" CenterY="9510.0" Width="1340.0" Height="300.0" ZOrder="28672"/> </Label> <Label TextLabel="Latrophilin" GraphId="bc3"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="3800.0" CenterY="2200.0" Width="860.0" Height="180.0" ZOrder="28672"/> </Label> <Label TextLabel="Class B orphan/other" GraphId="d1a"> <Graphics FontWeight="Bold" FontSize="120" Color="000000" CenterX="3800.0" CenterY="3850.0" Width="1625.0" Height="180.0" ZOrder="28672"/> </Label> <Group GroupId="c601b" GraphId="f1b61"/> <Group GroupId="ec598" GraphId="bf045"/> <Group GroupId="a60b5" GraphId="a1a83"/> <Group GroupId="a9b0a" GraphId="a74bf"/> <Group GroupId="b4223" GraphId="b885a"/> <Group GroupId="f02df" GraphId="b3f8c"/> <Group GroupId="fd1b2" GraphId="b5392"/> <InfoBox CenterX="76.5" CenterY="640.0"/> <Legend CenterX="5120.0" CenterY="1778.0"/> </Pathway>

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