Striated Muscle Contraction (Mus musculus)

<?xml version="1.0" encoding="UTF-8"?>
<Pathway xmlns="http://genmapp.org/GPML/2008a" Name="Striated Muscle Contraction" Organism="Mus musculus" License="CC BY 2.0">
  <Comment Source="GenMAPP notes"/>
  <Comment Source="GenMAPP remarks"/>
  <Comment Source="WikiPathways-category">Physiological Process</Comment>
  <Graphics BoardWidth="15422.0" BoardHeight="12782.0" WindowWidth="15363.0" WindowHeight="13530.0"/>
  <DataNode TextLabel="Myl4" Type="GeneProduct" BackpageHead="Myl4 | myosin light polypeptide 4" GraphId="e19" GroupRef="c76e4">
    <Graphics Color="000000" CenterX="11900.0" CenterY="10400.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17896"/>
  </DataNode>
  <DataNode TextLabel="Myl2" Type="GeneProduct" BackpageHead="Myl2 | myosin light polypeptide 2 regulatory..." GraphId="d85" GroupRef="c76e4">
    <Graphics Color="000000" CenterX="11900.0" CenterY="9800.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17906"/>
  </DataNode>
  <DataNode TextLabel="Myh6" Type="GeneProduct" BackpageHead="Myh6 | myosin heavy polypeptide 6 cardiac mu..." GraphId="e85" GroupRef="ab74e">
    <Graphics Color="000000" CenterX="8450.0" CenterY="4000.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17888"/>
  </DataNode>
  <DataNode TextLabel="Myh8" Type="GeneProduct" BackpageHead="Myh8 | myosin heavy polypeptide 8 skeletal m..." GraphId="e21" GroupRef="ab74e">
    <Graphics Color="000000" CenterX="8450.0" CenterY="4600.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17885"/>
  </DataNode>
  <DataNode TextLabel="Acta1" Type="GeneProduct" BackpageHead="Acta1 | actin alpha 1 skeletal muscle" GraphId="f78" GroupRef="ea5c2">
    <Graphics Color="000000" CenterX="6300.0" CenterY="10450.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="11459"/>
  </DataNode>
  <DataNode TextLabel="Actc1" Type="GeneProduct" BackpageHead="Actc1 | actin alpha cardiac" GraphId="c4f" GroupRef="ea5c2">
    <Graphics Color="000000" CenterX="6300.0" CenterY="11050.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="11464"/>
  </DataNode>
  <DataNode TextLabel="Tnni1" Type="GeneProduct" BackpageHead="Tnni1 | troponin I skeletal slow 1" GraphId="b65" GroupRef="dc0c4">
    <Graphics Color="000000" CenterX="5050.0" CenterY="6750.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21952"/>
  </DataNode>
  <DataNode TextLabel="Tnnt2" Type="GeneProduct" BackpageHead="Tnnt2 | troponin T2 cardiac" GraphId="a36" GroupRef="d1185">
    <Graphics Color="000000" CenterX="3150.0" CenterY="6750.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21956"/>
  </DataNode>
  <DataNode TextLabel="Tpm3" Type="GeneProduct" BackpageHead="Tpm3 | tropomyosin 3 gamma" GraphId="f3d" GroupRef="fa58d">
    <Graphics Color="000000" CenterX="1450.0" CenterY="8350.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="59069"/>
  </DataNode>
  <DataNode TextLabel="Dmd" Type="GeneProduct" BackpageHead="Dmd | dystrophin muscular dystrophy" GraphId="b05" GroupRef="f8dc5">
    <Graphics Color="000000" CenterX="3600.0" CenterY="4000.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="13405"/>
  </DataNode>
  <DataNode TextLabel="Vim" Type="GeneProduct" BackpageHead="Vim | vimentin" GraphId="c0c" GroupRef="e9047">
    <Graphics Color="000000" CenterX="10200.0" CenterY="3000.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="22352"/>
  </DataNode>
  <DataNode TextLabel="Tpm2" Type="GeneProduct" BackpageHead="Tpm2 | tropomyosin 2 beta" GraphId="c87" GroupRef="fa58d">
    <Graphics Color="000000" CenterX="1450.0" CenterY="8050.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="22004"/>
  </DataNode>
  <DataNode TextLabel="Tnni2" Type="GeneProduct" BackpageHead="Tnni2 | troponin I skeletal fast 2" GraphId="bd4" GroupRef="dc0c4">
    <Graphics Color="000000" CenterX="5050.0" CenterY="7050.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21953"/>
  </DataNode>
  <DataNode TextLabel="Tnni3" Type="GeneProduct" BackpageHead="Tnni3 | troponin I cardiac" GraphId="edd" GroupRef="dc0c4">
    <Graphics Color="000000" CenterX="5050.0" CenterY="7350.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21954"/>
  </DataNode>
  <DataNode TextLabel="Tnnt3" Type="GeneProduct" BackpageHead="Tnnt3 | troponin T3 skeletal fast" GraphId="edc" GroupRef="d1185">
    <Graphics Color="000000" CenterX="3150.0" CenterY="7350.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21957"/>
  </DataNode>
  <DataNode TextLabel="Tnnt1" Type="GeneProduct" BackpageHead="Tnnt1 | troponin T1 skeletal slow" GraphId="ac8" GroupRef="d1185">
    <Graphics Color="000000" CenterX="3150.0" CenterY="7050.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21955"/>
  </DataNode>
  <DataNode TextLabel="Tnnc1" Type="GeneProduct" BackpageHead="Tnnc1 | troponin C cardiac/slow skeletal" GraphId="af1" GroupRef="f63f6">
    <Graphics Color="000000" CenterX="6300.0" CenterY="8050.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21924"/>
  </DataNode>
  <DataNode TextLabel="Tnnc2" Type="GeneProduct" BackpageHead="Tnnc2 | troponin C2 fast" GraphId="a1f" GroupRef="f63f6">
    <Graphics Color="000000" CenterX="6300.0" CenterY="8350.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21925"/>
  </DataNode>
  <DataNode TextLabel="Myl3" Type="GeneProduct" BackpageHead="Myl3 | myosin light polypeptide 3" GraphId="adf" GroupRef="c76e4">
    <Comment Source="GenMAPP remarks">MLEV HUMAN</Comment>
    <Graphics Color="000000" CenterX="11900.0" CenterY="10100.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17897"/>
  </DataNode>
  <DataNode TextLabel="Myl1" Type="GeneProduct" BackpageHead="Myl1 | myosin light polypeptide 1" GraphId="f08" GroupRef="c76e4">
    <Graphics Color="000000" CenterX="11900.0" CenterY="9500.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17901"/>
  </DataNode>
  <DataNode TextLabel="Myh3" Type="GeneProduct" BackpageHead="Myh3 | myosin heavy polypeptide 3 skeletal m..." GraphId="c36" GroupRef="ab74e">
    <Graphics Color="000000" CenterX="7250.0" CenterY="4300.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17883"/>
  </DataNode>
  <DataNode TextLabel="Actn3" Type="GeneProduct" BackpageHead="Actn3 | actinin alpha 3" GraphId="caa" GroupRef="e9047">
    <Comment Source="GenMAPP remarks">AAC3 MOUSE</Comment>
    <Graphics Color="000000" CenterX="10200.0" CenterY="2400.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="11474"/>
  </DataNode>
  <DataNode TextLabel="Actn2" Type="GeneProduct" BackpageHead="Actn2 | actinin alpha 2" GraphId="db8" GroupRef="e9047">
    <Comment Source="GenMAPP remarks">AAC2 MOUSE</Comment>
    <Graphics Color="000000" CenterX="10200.0" CenterY="2100.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="11472"/>
  </DataNode>
  <DataNode TextLabel="Actn4" Type="GeneProduct" BackpageHead="Actn4 | actinin alpha 4" GraphId="fb7" GroupRef="e9047">
    <Graphics Color="000000" CenterX="10200.0" CenterY="1800.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="60595"/>
  </DataNode>
  <DataNode TextLabel="Tmod1" Type="GeneProduct" BackpageHead="Tmod1 | tropomodulin 1" GraphId="e0b" GroupRef="f8dc5">
    <Graphics Color="000000" CenterX="3600.0" CenterY="4300.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21916"/>
  </DataNode>
  <DataNode TextLabel="Neb" Type="GeneProduct" BackpageHead="Neb | nebulin" GraphId="b90" GroupRef="f8dc5">
    <Graphics Color="000000" CenterX="3600.0" CenterY="4600.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17996"/>
  </DataNode>
  <DataNode TextLabel="Myom1" Type="GeneProduct" BackpageHead="Myom1 | myomesin 1" GraphId="e35">
    <Graphics Color="000000" CenterX="12650.0" CenterY="2450.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17929"/>
  </DataNode>
  <DataNode TextLabel="Tcap" Type="GeneProduct" BackpageHead="Tcap | titin-cap" GraphId="f6f">
    <Graphics Color="000000" CenterX="11000.0" CenterY="4750.0" Width="800.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="21393"/>
  </DataNode>
  <DataNode TextLabel="Ttn" Type="GeneProduct" BackpageHead="Ttn | titin" GraphId="b02" GroupRef="d39a0">
    <Graphics Color="000000" CenterX="10250.0" CenterY="3850.0" Width="800.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="22138"/>
  </DataNode>
  <DataNode TextLabel="Des" Type="GeneProduct" BackpageHead="Des | desmin" GraphId="a7b" GroupRef="e9047">
    <Graphics Color="000000" CenterX="10200.0" CenterY="2700.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="13346"/>
  </DataNode>
  <DataNode TextLabel="Tpm4" Type="GeneProduct" BackpageHead="Tpm4 | tropomyosin 4" GraphId="da7" GroupRef="fa58d">
    <Graphics Color="000000" CenterX="1450.0" CenterY="8650.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="326618"/>
  </DataNode>
  <DataNode TextLabel="Tpm1" Type="GeneProduct" BackpageHead="Tpm1 | tropomyosin 1 alpha" GraphId="b0e" GroupRef="fa58d">
    <Comment Source="GenMAPP remarks">p10469</Comment>
    <Graphics Color="000000" CenterX="1450.0" CenterY="7750.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="22003"/>
  </DataNode>
  <DataNode TextLabel="Mybpc3" Type="GeneProduct" BackpageHead="Mybpc3 | myosin binding protein C cardiac" GraphId="bde" GroupRef="bb5f8">
    <Graphics Color="000000" CenterX="5700.0" CenterY="4600.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17868"/>
  </DataNode>
  <DataNode TextLabel="Mybpc2" Type="GeneProduct" BackpageHead="Mybpc2 | myosin binding protein C fast-type" GraphId="cef" GroupRef="bb5f8">
    <Graphics Color="000000" CenterX="5700.0" CenterY="4300.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="233199"/>
  </DataNode>
  <DataNode TextLabel="Mybpc1" Type="GeneProduct" BackpageHead="Mybpc1 | myosin binding protein C slow-type" GraphId="e09" GroupRef="bb5f8">
    <Graphics Color="000000" CenterX="5700.0" CenterY="4000.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="107738"/>
  </DataNode>
  <DataNode TextLabel="Acta2" Type="GeneProduct" BackpageHead="Acta2 | actin alpha 2 smooth muscle aorta" GraphId="f05" GroupRef="ea5c2">
    <Graphics Color="000000" CenterX="6300.0" CenterY="10750.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="11475"/>
  </DataNode>
  <DataNode TextLabel="Actg1" Type="GeneProduct" BackpageHead="Actg1 | actin gamma cytoplasmic 1" GraphId="bd5" GroupRef="ea5c2">
    <Graphics Color="000000" CenterX="6300.0" CenterY="11350.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="11465"/>
  </DataNode>
  <DataNode TextLabel="Myl9" Type="GeneProduct" BackpageHead="Myl9 | myosin light polypeptide 9 regulatory..." GraphId="ece" GroupRef="c76e4">
    <Graphics Color="000000" CenterX="11900.0" CenterY="10700.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="98932"/>
  </DataNode>
  <DataNode TextLabel="Myom2" Type="GeneProduct" BackpageHead="Myom2 | myomesin 2" GraphId="f28">
    <Graphics Color="000000" CenterX="12650.0" CenterY="2750.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17930"/>
  </DataNode>
  <DataNode TextLabel="Myh7" Type="GeneProduct" BackpageHead="Myh7 | myosin heavy polypeptide 7 cardiac mu..." GraphId="f38" GroupRef="ab74e">
    <Graphics Color="000000" CenterX="8450.0" CenterY="4300.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="140781"/>
  </DataNode>
  <DataNode TextLabel="Myh4" Type="GeneProduct" BackpageHead="Myh4 | myosin heavy polypeptide 4 skeletal m..." GraphId="d1d" GroupRef="ab74e">
    <Graphics Color="000000" CenterX="7250.0" CenterY="4600.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17884"/>
  </DataNode>
  <DataNode TextLabel="Myh1" Type="GeneProduct" BackpageHead="Myh1 | myosin heavy polypeptide 1 skeletal m..." GraphId="bec" GroupRef="ab74e">
    <Graphics Color="000000" CenterX="7250.0" CenterY="4000.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="17879"/>
  </DataNode>
  <DataNode TextLabel="Casq2" Type="GeneProduct" BackpageHead="Casq2 | calsequestrin 2" GraphId="a73">
    <Graphics Color="000000" CenterX="12650.0" CenterY="2150.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="12373"/>
  </DataNode>
  <DataNode TextLabel="2300003C06Rik" Type="GeneProduct" BackpageHead="2300003C06Rik | RIKEN cDNA 2300003C06 gene" GraphId="ff1" GroupRef="a56ac">
    <Graphics Color="000000" CenterX="12650.0" CenterY="1850.0" Width="1500.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="71912"/>
  </DataNode>
  <DataNode TextLabel="Smpx" Type="GeneProduct" BackpageHead="Smpx | small muscle protein X-linked" GraphId="edb">
    <Graphics Color="000000" CenterX="12650.0" CenterY="3050.0" Width="900.0" Height="300.0" ZOrder="32768"/>
    <Xref Database="Entrez Gene" ID="66106"/>
  </DataNode>
  <Line Style="Solid" GraphId="cce65">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="4350.0" y="2250.0"/>
      <Point x="8050.0" y="2250.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="be792">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="8550.0" y="2250.0"/>
      <Point x="9200.0" y="2250.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="fab75">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3250.0" y="2250.0"/>
      <Point x="3850.0" y="2250.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="d2551">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="1950.0"/>
      <Point x="5350.0" y="1950.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="dd2ff">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="2550.0"/>
      <Point x="5350.0" y="2550.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ba00b">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7100.0" y="1950.0"/>
      <Point x="8600.0" y="1950.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ddc28">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7100.0" y="2550.0"/>
      <Point x="8600.0" y="2550.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="d4f32">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="4350.0" y="2850.0"/>
      <Point x="8050.0" y="2850.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c9015">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="8550.0" y="2850.0"/>
      <Point x="9200.0" y="2850.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="d1d0b">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3250.0" y="2850.0"/>
      <Point x="3850.0" y="2850.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="b3677">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="2550.0"/>
      <Point x="5350.0" y="2550.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="f7ea7">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="3150.0"/>
      <Point x="5350.0" y="3150.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="f7066">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7100.0" y="2550.0"/>
      <Point x="8600.0" y="2550.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="b2836">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7100.0" y="3150.0"/>
      <Point x="8600.0" y="3150.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ce074">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="1400.0"/>
      <Point x="5350.0" y="1400.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="b7509">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7100.0" y="1400.0"/>
      <Point x="8600.0" y="1400.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ab34f">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="4350.0" y="1700.0"/>
      <Point x="8050.0" y="1700.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c6b20">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="8550.0" y="1700.0"/>
      <Point x="9200.0" y="1700.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c6276">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3250.0" y="1700.0"/>
      <Point x="3850.0" y="1700.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="bc6eb">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="1400.0"/>
      <Point x="5350.0" y="1400.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="fc514">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7100.0" y="1400.0"/>
      <Point x="8600.0" y="1400.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="a4069">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3850.0" y="1400.0"/>
      <Point x="3850.0" y="3150.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="a9579">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="8600.0" y="1400.0"/>
      <Point x="8600.0" y="3150.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="e5bf3">
    <Graphics ZOrder="12288" Color="ff0000">
      <Point x="4950.0" y="2600.0"/>
      <Point x="4950.0" y="3100.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="d4ab0">
    <Graphics ZOrder="12288" Color="ff0000">
      <Point x="4950.0" y="2600.0"/>
      <Point x="5750.0" y="2600.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="f0281">
    <Graphics ZOrder="12288" Color="ff0000">
      <Point x="4950.0" y="3100.0"/>
      <Point x="5750.0" y="3100.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="d3142">
    <Graphics ZOrder="12288" Color="ff0000">
      <Point x="5750.0" y="2600.0"/>
      <Point x="5750.0" y="3100.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="b7972">
    <Graphics ZOrder="12288" Color="ff0000">
      <Point x="5050.0" y="3100.0"/>
      <Point x="4250.0" y="6350.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="a8a66">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3885.0" y="3730.0" GraphRef="e4588" relX="0.5" relY="-1.0"/>
      <Point x="4450.0" y="3250.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ed295">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="7265.0" y="3410.0" GraphRef="b6b38" relX="-0.5" relY="-1.0"/>
      <Point x="6850.0" y="3050.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="b0f6d">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="9505.0" y="3800.0" GraphRef="acb86" relX="-1.0" relY="0.0"/>
      <Point x="8100.0" y="3000.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="fa403">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="11000.0" y="4600.0" GraphRef="f6f" relX="0.0" relY="-1.0"/>
      <Point x="10250.0" y="4000.0" GraphRef="b02" relX="0.0" relY="1.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c8456">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="9415.0" y="1865.0" GraphRef="fcedc" relX="-1.0" relY="-0.5"/>
      <Point x="8805.0" y="1875.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="e3c27">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="5750.0" y="3410.0" GraphRef="dc7e9" relX="0.0" relY="-1.0"/>
      <Point x="6250.0" y="3050.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c55e0">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="5515.0" y="10900.0" GraphRef="e33ba" relX="-1.0" relY="0.0"/>
      <Point x="5351.3149" y="10275.65745" GraphRef="f23" relX="1.0" relY="0.5"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c837c">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="5200.0" y="8600.0"/>
      <Point x="5200.0" y="8900.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="e39c2">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="5300.0" y="8600.0"/>
      <Point x="5300.0" y="8900.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c81f2">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="5300.0" y="8400.0"/>
      <Point x="5615.0" y="8127.6368286970455" GraphRef="e4d05" relX="-1.0" relY="0.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="a3c18">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="4950.0" y="8499.9843" GraphRef="ed1" relX="0.0" relY="-1.0"/>
      <Point x="5050.0" y="7620.0" GraphRef="daf19" relX="0.0" relY="1.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ed27d">
    <Graphics ZOrder="12288" Color="ffffff">
      <Point x="5200.0" y="8600.0"/>
      <Point x="5350.0" y="8600.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="fe3bf">
    <Graphics ZOrder="12288" Color="ffffff">
      <Point x="5200.0" y="8850.0"/>
      <Point x="5350.0" y="8850.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="a5f14">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="3488.75" y="7620.0" GraphRef="dde6c" relX="0.5" relY="1.0"/>
      <Point x="4550.0" y="8550.0" GraphRef="e2e" relX="0.0" relY="-1.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c91c1">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="2285.0" y="8090.0" GraphRef="ec332" relX="1.0" relY="0.0"/>
      <Point x="4000.0" y="8650.0" GraphRef="cbb" relX="-1.0" relY="0.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="a1ae4">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="5100.0" y="9200.0"/>
      <Point x="5950.0" y="8950.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="b4e68">
    <Graphics ZOrder="12288" Color="ffffff">
      <Point x="9200.0" y="8200.0"/>
      <Point x="9350.0" y="8200.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ac172">
    <Graphics ZOrder="12288" Color="ff0000">
      <Point x="9200.0" y="8650.0"/>
      <Point x="8450.0" y="9200.0" ArrowHead="Arrow"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="ce3a3">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="9250.0" y="8250.0"/>
      <Point x="9350.0" y="8150.0"/>
    </Graphics>
  </Line>
  <Line Style="Solid" GraphId="c80d1">
    <Graphics ZOrder="12288" Color="000000">
      <Point x="11000.0" y="8498.429218763027" GraphRef="a77" relX="0.0" relY="-1.0"/>
      <Point x="11416.25" y="8960.0" GraphRef="b8a89" relX="-0.5" relY="-1.0"/>
    </Graphics>
  </Line>
  <Label TextLabel="Myosin Light Chain" GraphId="e12" GroupRef="c76e4">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="11950.0" CenterY="9200.0" Width="1895.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Myosin Heavy Chain" GraphId="eeb" GroupRef="ab74e">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="7850.0" CenterY="3650.0" Width="2000.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Tropomyosin" GraphId="ad4" GroupRef="fa58d">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="1450.0" CenterY="7400.0" Width="1310.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Other Structural" GraphId="f61" GroupRef="a56ac">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="12750.0" CenterY="1300.0" Width="1595.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="M Disk" GraphId="f83">
    <Graphics FontWeight="Bold" FontSize="180" Color="000000" CenterX="6350.0" CenterY="1100.0" Width="845.0" Height="285.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Z Disk" GraphId="b73">
    <Graphics FontWeight="Bold" FontSize="180" Color="000000" CenterX="8600.0" CenterY="1100.0" Width="785.0" Height="285.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Z Disk" GraphId="c64">
    <Graphics FontWeight="Bold" FontSize="180" Color="000000" CenterX="4000.0" CenterY="1100.0" Width="785.0" Height="285.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Myosin Binding" GraphId="d7f" GroupRef="bb5f8">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="5750.0" CenterY="3650.0" Width="1535.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="A Model of Triggering of Striated Muscle" GraphId="a3d">
    <Graphics FontWeight="Bold" FontSize="210" Color="000000" CenterX="4900.0" CenterY="5750.0" Width="5330.0" Height="315.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Contraction by Ca++" GraphId="e14">
    <Graphics FontWeight="Bold" FontSize="210" Color="000000" CenterX="8950.0" CenterY="5750.0" Width="2750.0" Height="315.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Troponin-T" GraphId="c65" GroupRef="d1185">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="3150.0" CenterY="6450.0" Width="1115.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Troponin-I" GraphId="e96" GroupRef="dc0c4">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="5050.0" CenterY="6420.0" Width="1055.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Troponin-C" GraphId="ea1" GroupRef="f63f6">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="6300.0" CenterY="7750.0" Width="1130.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Actin" GraphId="bc9">
    <Graphics FontWeight="Bold" FontSize="150" Color="808080" CenterX="4400.0" CenterY="9900.0" Width="560.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Actin" GraphId="ef2">
    <Graphics FontWeight="Bold" FontSize="150" Color="808080" CenterX="9400.0" CenterY="9900.0" Width="560.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Myosin Binding Site" GraphId="e46">
    <Graphics FontWeight="Bold" FontStyle="Italic" FontSize="165" Color="000000" CenterX="6600.0" CenterY="8850.0" Width="2060.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="(Covered)" GraphId="e6d">
    <Graphics FontWeight="Bold" FontStyle="Italic" FontSize="165" Color="000000" CenterX="6100.0" CenterY="9100.0" Width="1070.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Ca" GraphId="c42">
    <Graphics FontWeight="Bold" FontSize="135" Color="000000" CenterX="8750.0" CenterY="8100.0" Width="305.0" Height="225.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Ca" GraphId="b4c">
    <Graphics FontWeight="Bold" FontSize="135" Color="000000" CenterX="9300.0" CenterY="8100.0" Width="305.0" Height="225.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Myosin Head" GraphId="bf8">
    <Graphics FontWeight="Bold" FontStyle="Italic" FontSize="165" Color="808080" CenterX="11200.0" CenterY="8450.0" Width="1325.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Label TextLabel="Regulatory Proteins" GraphId="d23" GroupRef="a56ac">
    <Graphics FontWeight="Bold" FontSize="150" Color="0000ff" CenterX="12750.0" CenterY="1550.0" Width="1955.0" Height="240.0" ZOrder="28672"/>
  </Label>
  <Shape Type="Arc" Style="Solid" GraphId="b0d">
    <Graphics FillColor="000000" Color="000000" CenterX="8100.0" CenterY="2250.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="a48">
    <Graphics FillColor="000000" Color="000000" CenterX="8200.0" CenterY="2300.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="c6d">
    <Graphics FillColor="000000" Color="000000" CenterX="8300.0" CenterY="2250.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="c8d">
    <Graphics FillColor="000000" Color="000000" CenterX="8400.0" CenterY="2300.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="d61">
    <Graphics FillColor="000000" Color="000000" CenterX="8500.0" CenterY="2250.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="daf">
    <Graphics FillColor="000000" Color="000000" CenterX="3900.0" CenterY="2250.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="fea">
    <Graphics FillColor="000000" Color="000000" CenterX="4000.0" CenterY="2300.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="cc5">
    <Graphics FillColor="000000" Color="000000" CenterX="4100.0" CenterY="2250.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="cd2">
    <Graphics FillColor="000000" Color="000000" CenterX="4200.0" CenterY="2300.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="b67">
    <Graphics FillColor="000000" Color="000000" CenterX="4300.0" CenterY="2250.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="a68">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4600.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="f21">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4850.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b09">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5100.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="eb8">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5350.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="a93">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5600.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="d4d">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5850.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b72">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6100.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b37">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6350.0" CenterY="2250.0" Width="100.0" Height="1902.63" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="f7b">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7600.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="f5e">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7850.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="c95">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6600.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b0b">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6850.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="c92">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7100.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="d20">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7350.0" CenterY="2250.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="bdf">
    <Graphics FillColor="000000" Color="000000" CenterX="8100.0" CenterY="2850.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="e20">
    <Graphics FillColor="000000" Color="000000" CenterX="8200.0" CenterY="2900.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="d73">
    <Graphics FillColor="000000" Color="000000" CenterX="8300.0" CenterY="2850.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="d56">
    <Graphics FillColor="000000" Color="000000" CenterX="8400.0" CenterY="2900.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="d99">
    <Graphics FillColor="000000" Color="000000" CenterX="8500.0" CenterY="2850.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="ed6">
    <Graphics FillColor="000000" Color="000000" CenterX="3900.0" CenterY="2850.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="f13">
    <Graphics FillColor="000000" Color="000000" CenterX="4000.0" CenterY="2900.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="c68">
    <Graphics FillColor="000000" Color="000000" CenterX="4100.0" CenterY="2850.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="d76">
    <Graphics FillColor="000000" Color="000000" CenterX="4200.0" CenterY="2900.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="e43">
    <Graphics FillColor="000000" Color="000000" CenterX="4300.0" CenterY="2850.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="d29">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4600.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="cbe">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4850.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="e33">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5100.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="acf">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5350.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b96">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5600.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="c76">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5850.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="fd3">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6100.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="a3a">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7600.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="a1a">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7850.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="aab">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6600.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="c6e">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6850.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b33">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7100.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="c5f">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7350.0" CenterY="2850.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="c7f">
    <Graphics FillColor="000000" Color="000000" CenterX="8100.0" CenterY="1700.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="fed">
    <Graphics FillColor="000000" Color="000000" CenterX="8200.0" CenterY="1750.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="edf">
    <Graphics FillColor="000000" Color="000000" CenterX="8300.0" CenterY="1700.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="c32">
    <Graphics FillColor="000000" Color="000000" CenterX="8400.0" CenterY="1750.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="aa4">
    <Graphics FillColor="000000" Color="000000" CenterX="8500.0" CenterY="1700.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="fa0">
    <Graphics FillColor="000000" Color="000000" CenterX="3900.0" CenterY="1700.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="b2a">
    <Graphics FillColor="000000" Color="000000" CenterX="4000.0" CenterY="1750.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="eaa">
    <Graphics FillColor="000000" Color="000000" CenterX="4100.0" CenterY="1700.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="de1">
    <Graphics FillColor="000000" Color="000000" CenterX="4200.0" CenterY="1750.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="3.141593"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="f4d">
    <Graphics FillColor="000000" Color="000000" CenterX="4300.0" CenterY="1700.0" Width="100.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b52">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4600.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="f96">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4850.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="ac5">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5100.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="e67">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5350.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="f06">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5600.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="aa2">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="5850.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="dcf">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6100.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="c6c">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7600.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="e32">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7850.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="eb6">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6600.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="a2b">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="6850.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="fe9">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7100.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="f01">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="7350.0" CenterY="1700.0" Width="100.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="ca7">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="8600.0" CenterY="2250.0" Width="100.0" Height="1902.63" ZOrder="16384" Rotation="0.002552152"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="bbf">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="3850.0" CenterY="2250.0" Width="100.0" Height="1902.63" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Brace" Style="Solid" GraphId="a35" GroupRef="d39a0">
    <Graphics FillColor="000000" Color="8f8f8f" CenterX="9690.0" CenterY="3800.0" Width="800.0" Height="130.0" ZOrder="16384" Rotation="4.71238898038469"/>
  </Shape>
  <Shape Type="Brace" Style="Solid" GraphId="fd0" GroupRef="e9047">
    <Graphics FillColor="000000" Color="8f8f8f" CenterX="9600.0" CenterY="2350.0" Width="1700.0" Height="130.0" ZOrder="16384" Rotation="4.71238898038469"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="f23">
    <Graphics FillColor="Transparent" Color="000000" CenterX="4400.0" CenterY="9800.0" Width="1902.6298" Height="1902.6298" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="cd6">
    <Graphics FillColor="000000" Color="000000" CenterX="2600.0" CenterY="9800.0" Width="1800.0" Height="1700.0" ZOrder="16384" Rotation="4.712389"/>
  </Shape>
  <Shape Type="Brace" Style="Solid" GraphId="cac" GroupRef="ea5c2">
    <Graphics FillColor="000000" Color="8f8f8f" CenterX="5700.0" CenterY="10900.0" Width="1400.0" Height="130.0" ZOrder="16384" Rotation="4.71238898038469"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="cbb">
    <Graphics FillColor="Transparent" Color="000000" CenterX="4200.0" CenterY="8650.0" Width="400.0" Height="400.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="ed1">
    <Graphics FillColor="Transparent" Color="000000" CenterX="4950.0" CenterY="8750.0" Width="510.247" Height="500.0314" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="e2e">
    <Graphics FillColor="Transparent" Color="000000" CenterX="4550.0" CenterY="8700.0" Width="300.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="e28">
    <Graphics FillColor="Transparent" Color="000000" CenterX="5250.0" CenterY="8500.0" Width="200.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="e4f">
    <Graphics FillColor="Transparent" Color="000000" CenterX="5250.0" CenterY="8950.0" Width="200.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Brace" Style="Solid" GraphId="b91" GroupRef="f63f6">
    <Graphics FillColor="000000" Color="8f8f8f" CenterX="5765.849496598849" CenterY="8187.521469420392" Width="875.2487005907743" Height="42.69143057626316" ZOrder="16384" Rotation="4.7059788117743775"/>
  </Shape>
  <Shape Type="Brace" Style="Solid" GraphId="a37" GroupRef="fa58d">
    <Graphics FillColor="000000" Color="8f8f8f" CenterX="2100.0" CenterY="8100.0" Width="1600.0" Height="130.0" ZOrder="16384" Rotation="1.5707963267948966"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="b21">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="4950.0" CenterY="9100.0" Width="600.0" Height="100.0" ZOrder="16384" Rotation="0.6193332"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="f9e">
    <Graphics FillColor="Transparent" Color="000000" CenterX="9400.0" CenterY="9800.0" Width="1902.6298" Height="1902.6298" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="c53">
    <Graphics FillColor="000000" Color="000000" CenterX="7600.0" CenterY="9800.0" Width="1800.0" Height="1700.0" ZOrder="16384" Rotation="4.712389"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="c0d">
    <Graphics FillColor="Transparent" Color="000000" CenterX="8450.0" CenterY="9150.0" Width="400.0" Height="400.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="fc6">
    <Graphics FillColor="Transparent" Color="000000" CenterX="8750.0" CenterY="8950.0" Width="300.0" Height="300.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="d4e">
    <Graphics FillColor="Transparent" Color="000000" CenterX="9050.0" CenterY="8650.0" Width="510.247" Height="500.0314" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="ef7">
    <Graphics FillColor="Transparent" Color="000000" CenterX="9250.0" CenterY="8350.0" Width="200.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="eff">
    <Graphics FillColor="0f0f0f" Color="000000" CenterX="9950.0" CenterY="9100.0" Width="600.0" Height="100.0" ZOrder="16384" Rotation="0.6193332"/>
  </Shape>
  <Shape Type="Oval" Style="Solid" GraphId="ec6">
    <Graphics FillColor="Transparent" Color="000000" CenterX="8850.0" CenterY="8350.0" Width="200.0" Height="200.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="aa6">
    <Graphics FillColor="Transparent" Color="000000" CenterX="9050.0" CenterY="8350.0" Width="200.0" Height="100.0" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="b46">
    <Graphics FillColor="000000" Color="000000" CenterX="10050.0" CenterY="9000.0" Width="500.0" Height="282.8428" ZOrder="16384" Rotation="3.926991"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="d04">
    <Graphics FillColor="000000" Color="000000" CenterX="9850.0" CenterY="8750.0" Width="100.0" Height="141.42136" ZOrder="16384" Rotation="0.7853982"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="efe">
    <Graphics FillColor="000000" Color="000000" CenterX="10300.0" CenterY="9150.0" Width="100.0" Height="141.42136" ZOrder="16384" Rotation="0.7853982"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="bc1">
    <Graphics FillColor="000000" Color="000000" CenterX="10600.0" CenterY="8500.0" Width="1676.3054" Height="400.0" ZOrder="16384" Rotation="2.788602"/>
  </Shape>
  <Shape Type="Arc" Style="Solid" GraphId="a77">
    <Graphics FillColor="000000" Color="000000" CenterX="11000.0" CenterY="8950.0" Width="1431.7822" Height="400.0" ZOrder="16384" Rotation="2.761086"/>
  </Shape>
  <Shape Type="Rectangle" Style="Solid" GraphId="da5" GroupRef="a56ac">
    <Graphics FillColor="Transparent" Color="000000" CenterX="12700.0" CenterY="2200.0" Width="2400.0" Height="2102.38" ZOrder="16384" Rotation="0.0"/>
  </Shape>
  <Group GroupId="a56ac" Style="Complex"/>
  <Group GroupId="e9047" GraphId="fcedc" Style="Complex"/>
  <Group GroupId="d39a0" GraphId="acb86" Style="Complex"/>
  <Group GroupId="ab74e" GraphId="b6b38" Style="Complex"/>
  <Group GroupId="bb5f8" GraphId="dc7e9" Style="Complex"/>
  <Group GroupId="f8dc5" GraphId="e4588" Style="Complex"/>
  <Group GroupId="dc0c4" GraphId="daf19" Style="Complex"/>
  <Group GroupId="d1185" GraphId="dde6c" Style="Complex"/>
  <Group GroupId="f63f6" GraphId="e4d05" Style="Complex"/>
  <Group GroupId="fa58d" GraphId="ec332" Style="Complex"/>
  <Group GroupId="c76e4" GraphId="b8a89" Style="Complex"/>
  <Group GroupId="ea5c2" GraphId="e33ba" Style="Complex"/>
  <InfoBox CenterX="75.0" CenterY="75.0"/>
  <Legend CenterX="11925.0" CenterY="3825.0"/>
</Pathway>