Cell survival blockade-delete (Homo sapiens)

<?xml version="1.0" encoding="UTF-8"?>
<Pathway xmlns="http://genmapp.org/GPML/2010a" Name="Cell survival blockade" Author="Frank Raven" Organism="Homo sapiens">
  <Graphics BoardWidth="911.0" BoardHeight="488.0" />
  <DataNode TextLabel="Quercetin" GraphId="c13e2" Type="Metabolite">
    <Graphics CenterX="652.5" CenterY="47.5" Width="97.0" Height="27.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="" ID="" />
  </DataNode>
  <DataNode TextLabel="PI 3-kinase/AKT" GraphId="eb5ba" Type="Protein">
    <Graphics CenterX="806.4499999999999" CenterY="163.82500000000033" Width="83.5" Height="26.25" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl" ID="" />
  </DataNode>
  <DataNode TextLabel="ERK" GraphId="c0a06" Type="GeneProduct">
    <Graphics CenterX="646.25" CenterY="261.5" Width="89.5" Height="27.5" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl Human" ID="ENSG00000100030" />
  </DataNode>
  <DataNode TextLabel="MAPK8" GraphId="d0d80" Type="GeneProduct">
    <Graphics CenterX="529.75" CenterY="261.5" Width="92.5" Height="29.0" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl Human" ID="ENSG00000107643" />
  </DataNode>
  <DataNode TextLabel="PKC" GraphId="ecd17" Type="Protein">
    <Graphics CenterX="414.75" CenterY="259.25" Width="86.5" Height="25.5" ZOrder="32768" FontSize="10" Valign="Middle" />
    <Xref Database="Ensembl Human" ID="ENSG00000027075" />
  </DataNode>
  <Line>
    <Graphics ZOrder="12288" LineThickness="1.0" Color="ff0000">
      <Point X="652.5" Y="61.0" GraphRef="c13e2" RelX="0.0" RelY="1.0" />
      <Point X="806.4499999999999" Y="150.70000000000033" GraphRef="eb5ba" RelX="0.0" RelY="-1.0" ArrowHead="TBar" />
    </Graphics>
  </Line>
  <Line>
    <Graphics ZOrder="12288" LineThickness="1.0" Color="00ff00">
      <Point X="806.4499999999999" Y="176.95000000000033" GraphRef="eb5ba" RelX="0.0" RelY="1.0" />
      <Point X="724.75" Y="419.5" GraphRef="e6002" RelX="0.0" RelY="-1.0" ArrowHead="TBar" />
    </Graphics>
  </Line>
  <Line>
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="553.25" Y="174.0" GraphRef="d8b50" RelX="0.0" RelY="1.0" />
      <Point X="646.25" Y="247.75" GraphRef="c0a06" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Line>
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="553.25" Y="174.0" GraphRef="d8b50" RelX="0.0" RelY="1.0" />
      <Point X="529.75" Y="247.0" GraphRef="d0d80" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Line>
    <BiopaxRef>ad5</BiopaxRef>
    <Graphics ZOrder="12288" LineThickness="1.0" Color="33ff00">
      <Point X="529.75" Y="276.0" GraphRef="d0d80" RelX="0.0" RelY="1.0" />
      <Point X="542.25" Y="416.0" GraphRef="d2ed5" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Line>
    <BiopaxRef>ad5</BiopaxRef>
    <Graphics ZOrder="12288" LineThickness="1.0" Color="33ff00">
      <Point X="646.25" Y="275.25" GraphRef="c0a06" RelX="0.0" RelY="1.0" />
      <Point X="542.25" Y="416.0" GraphRef="d2ed5" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Line>
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="652.5" Y="61.0" GraphRef="c13e2" RelX="0.0" RelY="1.0" />
      <Point X="553.25" Y="142.5" GraphRef="d8b50" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Line>
    <Graphics ZOrder="12288" LineThickness="1.0">
      <Point X="553.25" Y="174.0" GraphRef="d8b50" RelX="0.0" RelY="1.0" />
      <Point X="414.75" Y="246.5" GraphRef="ecd17" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Line>
    <BiopaxRef>ad5</BiopaxRef>
    <Graphics ZOrder="12288" LineThickness="1.0" Color="33ff00">
      <Point X="414.0" Y="272.0" />
      <Point X="542.25" Y="416.0" GraphRef="d2ed5" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
    </Graphics>
  </Line>
  <Shape TextLabel="blockade of cell &#xA;survival/proliferation" GraphId="e6002">
    <Graphics CenterX="724.75" CenterY="434.75" Width="114.5" Height="30.5" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" />
  </Shape>
  <Shape TextLabel="Apoptosis" GraphId="d2ed5">
    <Graphics CenterX="542.25" CenterY="431.0" Width="97.5" Height="30.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" />
  </Shape>
  <Shape TextLabel="MAPKs" GraphId="d8b50">
    <Graphics CenterX="553.25" CenterY="158.25" Width="97.5" Height="31.5" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" />
  </Shape>
  <InfoBox CenterX="0.0" CenterY="0.0" />
  <Biopax>
    <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="ad5">
      <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">18324708</bp:ID>
      <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
      <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Time-course regulation of quercetin on cell survival/proliferation pathways in human hepatoma cells.</bp:TITLE>
      <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mol Nutr Food Res</bp:SOURCE>
      <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2008</bp:YEAR>
      <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Granado-Serrano AB</bp:AUTHORS>
      <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Angeles Martín M</bp:AUTHORS>
      <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bravo L</bp:AUTHORS>
      <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Goya L</bp:AUTHORS>
      <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ramos S</bp:AUTHORS>
    </bp:PublicationXref>
  </Biopax>
</Pathway>