Sterol regulatory element-binding proteins (SREBP) signaling (Homo sapiens)

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<Pathway xmlns="http://genmapp.org/GPML/2010a" Name="SREBP signalling" Version="20110318" Author="Sabine Daemen" Organism="Homo sapiens">
  <Comment Source="WikiPathways-category">Cellular Process</Comment>
  <Comment Source="WikiPathways-description">Sterol regulatory element-binding proteins (SREBPs) are membrane-bound proteins that act as transcription factors. They regulate lipid, especially cholesterol, biosynthesis and uptake at a transcriptional level to maintain cellular lipid homeostasis. In addition, SREBP appears to be involved in a variety of other cellular processes. This pathway of SREBP focusses on the regulation of lipid metabolism by SREBP. The data on which this pathway is based comes from a variety of in vitro and in vivo studies using different species, including mouse, rat, hamster and human. </Comment>
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