Crabtree effect (Saccharomyces cerevisiae)

From WikiPathways

You do not have permission to edit pages, for the following reasons:

• You do not have permission to edit pages in the Pathway namespace.
• You are not allowed to execute the action you have requested.

You can view and copy the source of this page:

<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Crabtree effect" Author="Alda J. Rodrigues" Organism="Saccharomyces cerevisiae"> <Graphics BoardWidth="798.6666666666667" BoardHeight="1012.6666666666665" /> <DataNode TextLabel="Glucose" GraphId="d7b85" Type="Metabolite"> <Graphics CenterX="400.33371988932294" CenterY="69.0" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB00122" /> </DataNode> <DataNode TextLabel="Glucose 6-P" GraphId="aa8b8" Type="Metabolite"> <Graphics CenterX="399.00038655598956" CenterY="134.0" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB01401" /> </DataNode> <DataNode TextLabel="Fructose 6-P" GraphId="e5fb6" Type="Metabolite"> <Graphics CenterX="399.00038655598956" CenterY="206.5" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB00124" /> </DataNode> <DataNode TextLabel="Fructose 1,6-P" GraphId="f12bb" Type="Metabolite"> <Graphics CenterX="399.00038655598956" CenterY="269.5" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB01058" /> </DataNode> <DataNode TextLabel="Glyceraldehyde 3-P" GraphId="e2e1e" Type="Metabolite"> <Graphics CenterX="399.00038655598956" CenterY="339.5" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB01112" /> </DataNode> <DataNode TextLabel="3- Phosphoglycerate" GraphId="edc87" Type="Metabolite"> <Graphics CenterX="399.00038655598956" CenterY="410.5" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Phosphoenolpyruvate" GraphId="d7e10" Type="Metabolite"> <Graphics CenterX="399.00038655598956" CenterY="472.5" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Pyruvate" GraphId="d7b68" Type="Metabolite"> <Graphics CenterX="398.6666666666663" CenterY="538.5317993164062" Width="66.6666666666671" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Acetaldehyde" GraphId="a81ad" Type="Metabolite"> <Graphics CenterX="539.5" CenterY="539.8651326497395" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB00990" /> </DataNode> <DataNode TextLabel="Ethanol" GraphId="ea36d" Type="Metabolite"> <Graphics CenterX="610.1666666666661" CenterY="442.0000000000001" Width="119.0" Height="31.999999999999847" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB00108" /> </DataNode> <DataNode TextLabel="Acetate" GraphId="f50eb" Type="Metabolite"> <Graphics CenterX="698.0000000000006" CenterY="539.8651326497396" Width="119.0" Height="31.999999999999847" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Oxaloacetate" GraphId="a2413" Type="Metabolite"> <Graphics CenterX="198.5" CenterY="539.8651326497395" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="DHAP&#xA;" GraphId="c6087" Type="Metabolite"> <Graphics CenterX="196.6666666666667" CenterY="339.3333333333337" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB01473" /> </DataNode> <DataNode TextLabel="Glycerol 3-P" GraphId="d92a3" Type="Metabolite"> <Graphics CenterX="195.0" CenterY="424.66666666666725" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB00126" /> </DataNode> <DataNode TextLabel="Glycerol" GraphId="bf957" Type="Metabolite"> <Graphics CenterX="194.83333333333337" CenterY="497.6666666666672" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB00131" /> </DataNode> <DataNode TextLabel="Glyoxylate" GraphId="ebf46" Type="Metabolite"> <Graphics CenterX="403.99999999999983" CenterY="788.0000000000014" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Acetyl-CoA" GraphId="bdfd8" Type="Metabolite"> <Graphics CenterX="698.0000000000006" CenterY="617.3333333333334" Width="119.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB01206" /> </DataNode> <DataNode TextLabel="TPI1&#xA;" GraphId="c95a4" Type="Protein"> <Graphics CenterX="287.66666666666646" CenterY="390.6666666666677" Width="52.00000000000159" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Oxaloacetate" GraphId="a5bf9" Type="Metabolite"> <Graphics CenterX="397.3333333333332" CenterY="665.8333333333334" Width="119.0" Height="20.0" ZOrder="32769" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="alpha- ketoglutarate" GraphId="c2019" Type="Metabolite"> <Graphics CenterX="533.3333333333335" CenterY="909.3333333333358" Width="119.0" Height="20.0" ZOrder="32771" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Isocitrate" GraphId="fd812" Type="Metabolite"> <Graphics CenterX="562.6666666666654" CenterY="821.750000000002" Width="119.0" Height="20.0" ZOrder="32772" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Succinate" GraphId="d82de" Type="Metabolite"> <Graphics CenterX="397.33333333333314" CenterY="972.6666666666665" Width="119.0" Height="20.0" ZOrder="32773" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Fumarate" GraphId="e4d71" Type="Metabolite"> <Graphics CenterX="257.0833333333337" CenterY="909.3333333333358" Width="119.0" Height="20.0" ZOrder="32774" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Malate" GraphId="f8f84" Type="Metabolite"> <Graphics CenterX="257.0833333333337" CenterY="732.4166666666675" Width="119.0" Height="20.0" ZOrder="32775" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="PDC2&#xA;" GraphId="ac840" Type="Protein"> <Graphics CenterX="451.99999999999966" CenterY="502.0000000000002" Width="52.00000000000159" Height="20.0" ZOrder="32776" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ADH1&#xA;" GraphId="f0482" Type="Protein"> <Graphics CenterX="627.9999999999993" CenterY="496.66666666666697" Width="52.00000000000159" Height="20.0" ZOrder="32777" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="GDP1&#xA;" GraphId="e3473" Type="Protein"> <Graphics CenterX="121.99999999999972" CenterY="371.6666666666677" Width="52.00000000000159" Height="20.0" ZOrder="32779" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="GDP2" GraphId="f821d" Type="Protein"> <Graphics CenterX="121.99999999999972" CenterY="391.6666666666677" Width="52.00000000000159" Height="20.0" ZOrder="32780" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="399.0" Y="80.0" /> <Point X="399.00038655598956" Y="124.0" GraphRef="aa8b8" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="399.0" Y="142.0" /> <Point X="399.00038655598956" Y="196.5" GraphRef="e5fb6" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="399.0" Y="216.5" /> <Point X="399.00038655598956" Y="259.5" GraphRef="f12bb" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="399.0" Y="277.5" /> <Point X="399.00038655598956" Y="329.5" GraphRef="e2e1e" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="398.61838785807294" Y="348.5" /> <Point X="399.00038655598956" Y="400.5" GraphRef="edc87" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="398.63816324869794" Y="418.5" /> <Point X="399.00038655598956" Y="462.5" GraphRef="d7e10" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="399.0" Y="483.0" /> <Point X="398.6666666666663" Y="528.5317993164062" GraphRef="d7b68" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="431.99999999999983" Y="538.5317993164062" GraphRef="d7b68" RelX="1.0" RelY="0.0" /> <Point X="480.0" Y="539.8651326497395" GraphRef="a81ad" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="365.33333333333275" Y="538.5317993164062" GraphRef="d7b68" RelX="-1.0" RelY="0.0" /> <Point X="258.0" Y="539.8651326497395" GraphRef="a2413" RelX="1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="236.6666666666667" Y="339.3333333333337" GraphRef="c6087" RelX="1.0" RelY="0.0" /> <Point X="339.50038655598956" Y="339.5" GraphRef="e2e1e" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="196.6666666666667" Y="349.3333333333337" GraphRef="c6087" RelX="0.0" RelY="1.0" /> <Point X="195.0" Y="414.66666666666725" GraphRef="d92a3" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="195.0" Y="434.66666666666725" GraphRef="d92a3" RelX="0.0" RelY="1.0" /> <Point X="194.83333333333337" Y="487.6666666666672" GraphRef="bf957" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0"> <Point X="439.0" Y="133.0" /> <Point X="522.6666666666667" Y="132.66666666666669" GraphRef="b5c43" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0"> <Point X="198.5" Y="549.8651326497395" /> <Point X="367.5833333333332" Y="655.8333333333334" GraphRef="a5bf9" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="580.0" Y="539.1449584960938" /> <Point X="638.5000000000006" Y="539.8651326497397" GraphRef="f50eb" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="539.5" Y="529.8651326497395" GraphRef="a81ad" RelX="0.0" RelY="-1.0" /> <Point X="610.1666666666661" Y="458.0" GraphRef="ea36d" RelX="0.0" RelY="1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="698.0000000000006" Y="555.8651326497397" GraphRef="f50eb" RelX="0.0" RelY="1.0" /> <Point X="698.0000000000006" Y="607.3333333333334" GraphRef="bdfd8" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineStyle="Broken" LineThickness="1.0"> <Point X="657.3333333333334" Y="622.6666666666666" /> <Point X="490.0" Y="693.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="512.0" Y="709.3333333333334" /> <Point X="523.0" Y="721.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="536.0" Y="741.0" /> <Point X="545.0" Y="761.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="554.0" Y="791.0" /> <Point X="557.0" Y="810.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="542.6666666666666" Y="884.6666666666666" /> <Point X="536.6666666666666" Y="898.6666666666666" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="477.3333333333333" Y="957.3333333333334" /> <Point X="457.3333333333333" Y="968.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="274.0" Y="928.0" /> <Point X="268.0" Y="920.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="244.66666666666666" Y="756.6666666666666" /> <Point X="251.33333333333334" Y="742.6666666666665" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="328.66666666666663" Y="673.3333333333333" /> <Point X="337.3333333333333" Y="670.6666666666666" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0"> <Point X="524.6666666666666" Y="831.3333333333334" /> <Point X="397.33333333333314" Y="962.6666666666665" GraphRef="d82de" RelX="0.0" RelY="-1.0" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="399.3333333333333" Y="950.0" /> <Point X="397.3333333333333" Y="961.3333333333334" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0"> <Point X="503.3333333333333" Y="823.3333333333334" /> <Point X="406.6666666666667" Y="777.8750000000005" /> <Point X="316.5833333333337" Y="732.4166666666675" GraphRef="f8f84" RelX="1.0" RelY="0.0" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="326.0" Y="732.6666666666666" /> <Point X="317.3333333333333" Y="732.6666666666666" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="435.3333333333333" Y="807.3333333333334" /> <Point X="423.3333333333333" Y="797.3333333333334" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ConnectorType="Curved" ZOrder="12288" LineThickness="1.0"> <Point X="397.0" Y="547.0" /> <Point X="396.0" Y="582.1666666666667" /> <Point X="638.5000000000006" Y="617.3333333333334" GraphRef="bdfd8" RelX="-1.0" RelY="0.0" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="620.0" Y="616.0" /> <Point X="638.5000000000006" Y="617.3333333333334" GraphRef="bdfd8" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="324.0" Y="965.3333333333333" /> <Point X="338.6666666666667" Y="972.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="246.0" Y="889.0" /> <Point X="253.0" Y="899.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="277.0" Y="709.0" /> <Point X="266.0" Y="723.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="247.33333333333334" Y="339.3333333333333" /> <Point X="236.6666666666667" Y="339.3333333333337" GraphRef="c6087" RelX="1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="32781" LineThickness="1.0"> <Point X="142.66666666666669" Y="381.33333333333377" /> <Point X="200.0" Y="380.6666666666672" ArrowHead="mim-catalysis" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="32782" LineThickness="1.0"> <Point X="287.66666666666646" Y="380.6666666666677" GraphRef="c95a4" RelX="0.0" RelY="-1.0" /> <Point X="287.66666666666697" Y="335.00000000000017" ArrowHead="mim-catalysis" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="32783" LineThickness="1.0"> <Point X="451.99999999999966" Y="512.0000000000002" GraphRef="ac840" RelX="0.0" RelY="1.0" /> <Point X="453.3333333333333" Y="542.6666666666667" ArrowHead="mim-catalysis" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction> <Graphics ZOrder="32784" LineThickness="1.0"> <Point X="601.9999999999985" Y="496.66666666666697" GraphRef="f0482" RelX="-1.0" RelY="0.0" /> <Point X="566.6666666666666" Y="497.33333333333326" ArrowHead="mim-catalysis" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Label TextLabel="OXIDATIVE PENTOSE PHOSPHATE PATHWAY" GraphId="b5c43"> <Graphics CenterX="645.6666666666667" CenterY="132.66666666666669" Width="246.0" Height="20.0" ZOrder="28672" FillColor="ffffff" FontSize="10" Valign="Middle" /> </Label> <Shape GraphId="fe8d0"> <Graphics CenterX="394.4166666666662" CenterY="820.4166666666654" Width="325.83333333333303" Height="319.1666666666687" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Oval" Rotation="0.0" /> </Shape> <InfoBox CenterX="0.0" CenterY="0.0" /> <Biopax /> </Pathway>

Return to Crabtree effect (Saccharomyces cerevisiae).