Splicing factor NOVA regulated synaptic proteins (Homo sapiens)

From WikiPathways

You do not have permission to edit pages, for the following reasons:

• You do not have permission to edit pages in the Pathway namespace.
• You are not allowed to execute the action you have requested.

You can view and copy the source of this page:

<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Splicing factor NOVA regulated synaptic proteins" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">Synaptic Communication influenced by NOVA-splicing regulation</Comment> <Comment Source="HomologyMapper">This pathway was inferred from Mus musculus pathway [http://wikipathways.org/instance/WP1983_r89961 WP1983 (rev 89961)] with a 85.0% conversion rate.</Comment> <BiopaxRef>adb</BiopaxRef> <BiopaxRef>ffd</BiopaxRef> <Graphics BoardWidth="1193.3333333333312" BoardHeight="1278.0" /> <DataNode TextLabel="CAV2" GraphId="d1ba0" Type="GeneProduct" GroupRef="dba10"> <Comment>Validated target - predicted by splicing microarray </Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000000058</Comment> <Graphics CenterX="271.12901892926436" CenterY="776.6245293329515" Width="80.0" Height="20.0" ZOrder="32768" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000105971" /> </DataNode> <DataNode TextLabel="EPB41L2" GraphId="d493e" Type="GeneProduct" GroupRef="c9e8e"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13822</Comment> <Graphics CenterX="657.4697116942012" CenterY="767.8156516574882" Width="48.37490551776263" Height="20.0" ZOrder="32770" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000079819" /> </DataNode> <DataNode TextLabel="MAPK4" GraphId="c9da6" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024558</Comment> <Graphics CenterX="67.0" CenterY="1045.0" Width="80.0" Height="20.0" ZOrder="32772" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000141639" /> </DataNode> <DataNode TextLabel="CDH2" GraphId="a00d1" Type="GeneProduct" GroupRef="e644e"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12558</Comment> <Graphics CenterX="317.6035579809414" CenterY="635.8252824002288" Width="199.0" Height="20.0" ZOrder="32774" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSG00000170558" /> </DataNode> <DataNode TextLabel="LAR&#xA;" GraphId="dd2eb" Type="GeneProduct" GroupRef="a4735"> <Comment>Validated target - predicted by splicing microarray</Comment> <Graphics CenterX="313.5" CenterY="536.75" Width="171.0" Height="20.0" ZOrder="32776" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="SNW1" GraphId="d3e65" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:66354</Comment> <Graphics CenterX="105.0" CenterY="565.0" Width="80.0" Height="20.0" ZOrder="32778" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000100603" /> </DataNode> <DataNode TextLabel="MAP4" GraphId="b0917" Type="Protein"> <Comment>Validated target - predicted by bioinformatics</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:P27546</Comment> <Graphics CenterX="124.0" CenterY="869.0" Width="80.0" Height="20.0" ZOrder="32780" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="Ensembl" ID="ENSG00000047849" /> </DataNode> <DataNode TextLabel="AGRN" GraphId="f9841" Type="Protein"> <Comment>Validated target - predicted by splicing microarray </Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:A2ASQ1</Comment> <Graphics CenterX="383.0" CenterY="138.0" Width="86.0" Height="24.0" ZOrder="32782" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000188157" /> </DataNode> <DataNode TextLabel="CLSTN1" GraphId="e6ba2" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:65945</Comment> <Graphics CenterX="497.0" CenterY="665.75" Width="100.0" Height="20.0" ZOrder="32784" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000171603" /> </DataNode> <DataNode TextLabel="EphrinA5R" GraphId="aa89b" Type="GeneProduct" GroupRef="d2e54"> <Comment>Validated target - predicted by splicing microarray</Comment> <Graphics CenterX="470.6067394282451" CenterY="930.3106739428243" Width="149.0" Height="20.0" ZOrder="32786" FontSize="10" Valign="Middle" Color="ff6666" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="KCNJ6" GraphId="b32d1" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16522</Comment> <Graphics CenterX="485.0" CenterY="395.0" Width="80.0" Height="20.0" ZOrder="32788" FontSize="10" Valign="Middle" Color="3333ff" /> <Xref Database="Ensembl" ID="ENSG00000157542" /> </DataNode> <DataNode TextLabel="PIP2&#xA;" GraphId="ad095" Type="Metabolite"> <Graphics CenterX="492.5" CenterY="352.5" Width="33.0" Height="13.0" ZOrder="32792" FontSize="10" Valign="Middle" /> <Xref Database="HMDB" ID="HMDB10032" /> </DataNode> <DataNode TextLabel="CLASP1" GraphId="dd25a" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000064302</Comment> <Graphics CenterX="79.0" CenterY="915.0" Width="80.0" Height="20.0" ZOrder="32794" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000074054" /> </DataNode> <DataNode TextLabel="KCNMA1" GraphId="bd973" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16531</Comment> <Graphics CenterX="229.135956343053" CenterY="825.7280873138935" Width="80.0" Height="20.0" ZOrder="32796" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000156113" /> </DataNode> <DataNode TextLabel="CASK" GraphId="db93b" Type="GeneProduct" GroupRef="dba10"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031012</Comment> <Graphics CenterX="211.1290189292649" CenterY="766.3850150089569" Width="80.00000000000001" Height="19.99999999999994" ZOrder="32798" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000147044" /> </DataNode> <DataNode TextLabel="NCDN" GraphId="ab198" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26562</Comment> <Graphics CenterX="694.0" CenterY="388.0" Width="80.0" Height="20.0" ZOrder="32800" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000020129" /> </DataNode> <DataNode TextLabel="GlyRa2" GraphId="ed159" Type="GeneProduct" GroupRef="d7dd2"> <Comment>Validated target</Comment> <Graphics CenterX="542.0" CenterY="200.0" Width="80.0" Height="20.0" ZOrder="32802" FillColor="Transparent" FontSize="10" Valign="Middle" Color="66cc00" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="GABRG2" GraphId="f4b3a" Type="GeneProduct" GroupRef="b5b4b"> <Comment>Validated target </Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14406</Comment> <Graphics CenterX="538.0" CenterY="258.0" Width="100.0" Height="20.0" ZOrder="32804" FillColor="Transparent" FontSize="10" Valign="Middle" Color="66cc00" /> <Xref Database="Ensembl" ID="ENSG00000113327" /> </DataNode> <DataNode TextLabel="MAPK9" GraphId="d2221" Type="GeneProduct"> <Comment>Validated target - predicted by CLIP</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26420</Comment> <Graphics CenterX="65.0" CenterY="1002.0" Width="80.0" Height="20.0" ZOrder="32806" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff00ff" /> <Xref Database="Ensembl" ID="ENSG00000050748" /> </DataNode> <DataNode TextLabel="ATP2B1" GraphId="da9ba" Type="GeneProduct" GroupRef="ece36"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67972</Comment> <Graphics CenterX="270.47527268150344" CenterY="686.2386486182991" Width="80.00000000000001" Height="20.000000000000064" ZOrder="32808" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000070961" /> </DataNode> <DataNode TextLabel="Syntaxin1" GraphId="c1258" Type="GeneProduct" GroupRef="e787b"> <Graphics CenterX="241.0" CenterY="383.0" Width="80.0" Height="20.0" ZOrder="32810" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="PLCB4" GraphId="fb864" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000039943</Comment> <Graphics CenterX="141.0" CenterY="154.0" Width="80.0" Height="18.0" ZOrder="32812" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000101333" /> </DataNode> <DataNode TextLabel="RAP1GAP" GraphId="e0a1c" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:110351</Comment> <Graphics CenterX="668.5915127955943" CenterY="663.5446496058747" Width="80.0" Height="20.0" ZOrder="32816" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000076864" /> </DataNode> <DataNode TextLabel="STX2" GraphId="cff16" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13852</Comment> <Graphics CenterX="212.0" CenterY="434.0" Width="80.0" Height="20.0" ZOrder="32818" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000111450" /> </DataNode> <DataNode TextLabel="CAMK2G" GraphId="bf4ee" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000021820</Comment> <Graphics CenterX="650.0" CenterY="464.0" Width="80.0" Height="20.0" ZOrder="32820" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000148660" /> </DataNode> <DataNode TextLabel="a-catenin&#xA;" GraphId="aaf0e" Type="GeneProduct" GroupRef="e644e"> <Comment>Validated target - predicted by splicing microarray</Comment> <Graphics CenterX="189.0" CenterY="643.0" Width="80.0" Height="20.0" ZOrder="32822" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CADM1" GraphId="f4187" Type="GeneProduct" GroupRef="c8aa0"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:54725</Comment> <Graphics CenterX="553.4406248362875" CenterY="875.5816452948353" Width="83.5" Height="26.5" ZOrder="32824" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000182985" /> </DataNode> <DataNode TextLabel="NEO1" GraphId="e4395" Type="GeneProduct"> <Comment>Validated target - predicted by CLIP</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18007</Comment> <Graphics CenterX="179.0" CenterY="1104.0" Width="80.0" Height="20.0" ZOrder="32826" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff00ff" /> <Xref Database="Ensembl" ID="ENSG00000067141" /> </DataNode> <DataNode TextLabel="nAChRa2" GraphId="a8f2f" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Graphics CenterX="532.0" CenterY="153.0" Width="80.0" Height="20.0" ZOrder="32828" FillColor="Transparent" FontSize="10" Valign="Middle" Color="0033ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CAV2" GraphId="c40fd" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000000058</Comment> <Graphics CenterX="214.0" CenterY="188.0" Width="80.0" Height="20.0" ZOrder="32830" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000105971" /> </DataNode> <DataNode TextLabel="CASK" GraphId="a241b" Type="GeneProduct" GroupRef="e787b"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031012</Comment> <Graphics CenterX="174.0" CenterY="365.0" Width="80.0" Height="20.0" ZOrder="32834" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000147044" /> </DataNode> <DataNode TextLabel="GPHN" GraphId="debf1" Type="GeneProduct" GroupRef="b5b4b"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:268566</Comment> <Graphics CenterX="618.0" CenterY="246.0" Width="80.0" Height="20.0" ZOrder="32836" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000171723" /> </DataNode> <DataNode TextLabel="CSN3" GraphId="f6d68" Type="Protein" GroupRef="ece36"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:P06796</Comment> <Graphics CenterX="199.371714700562" CenterY="692.8955763133624" Width="80.00000000000003" Height="20.000000000000064" ZOrder="32838" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000171209" /> </DataNode> <DataNode TextLabel="DAB1" GraphId="eb63a" Type="GeneProduct" GroupRef="b1604"> <Comment>Validated target - predicted by bioinformatics</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000028519</Comment> <Graphics CenterX="161.0" CenterY="271.0" Width="80.0" Height="20.0" ZOrder="32840" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="Ensembl" ID="ENSG00000173406" /> </DataNode> <DataNode TextLabel="APLP2" GraphId="ec517" Type="GeneProduct" GroupRef="b1604"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031996</Comment> <Graphics CenterX="225.5" CenterY="261.0" Width="71.0" Height="20.0" ZOrder="32842" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000084234" /> </DataNode> <DataNode TextLabel="KCNQ2" GraphId="ba43b" Type="GeneProduct" GroupRef="e88a6"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000016346</Comment> <Graphics CenterX="249.0" CenterY="1052.0" Width="80.0" Height="20.0" ZOrder="32844" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000075043" /> </DataNode> <DataNode TextLabel="STXBP2" GraphId="f5e8b" Type="GeneProduct" GroupRef="e787b"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20911</Comment> <Graphics CenterX="112.0" CenterY="351.0" Width="80.0" Height="20.0" ZOrder="32846" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000076944" /> </DataNode> <DataNode TextLabel="EPB41" GraphId="b630d" Type="GeneProduct" GroupRef="c9e8e"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269587</Comment> <Graphics CenterX="625.3715581470683" CenterY="749.0612244897959" Width="48.37490551776283" Height="20.0" ZOrder="32848" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000159023" /> </DataNode> <DataNode TextLabel="EPB41L3" GraphId="beaea" Type="GeneProduct" GroupRef="c8aa0"> <Comment>Validated target - predicted by splicing microarray </Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13823</Comment> <Graphics CenterX="676.7021137766823" CenterY="860.1897594709512" Width="65.05129035741314" Height="20.0" ZOrder="32850" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000082397" /> </DataNode> <DataNode TextLabel="CHL1" GraphId="e27ad" Type="GeneProduct" GroupRef="d9b60"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000030077</Comment> <Graphics CenterX="315.75" CenterY="990.75" Width="196.5" Height="22.5" ZOrder="32852" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000134121" /> </DataNode> <DataNode TextLabel="NTNG1" GraphId="ba6f0" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80883</Comment> <Graphics CenterX="339.13616240146854" CenterY="1080.0" Width="80.0" Height="20.0" ZOrder="32854" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000162631" /> </DataNode> <DataNode TextLabel="TERF2IP" GraphId="c6a39" Type="GeneProduct"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57321</Comment> <Graphics CenterX="680.0" CenterY="710.0" Width="80.0" Height="20.0" ZOrder="32856" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSG00000166848" /> </DataNode> <DataNode TextLabel="EFNA5" GraphId="edc77" Type="GeneProduct" GroupRef="d2e54"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640</Comment> <Graphics CenterX="318.1079257099665" CenterY="930.0" Width="158.21585141993302" Height="20.0" ZOrder="32858" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000184349" /> </DataNode> <DataNode TextLabel="GRIN2B" GraphId="d9539" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14812</Comment> <Graphics CenterX="496.0" CenterY="691.0" Width="100.0" Height="20.0" ZOrder="32860" FillColor="Transparent" FontSize="10" Valign="Middle" Color="0033ff" /> <Xref Database="Ensembl" ID="ENSG00000273079" /> </DataNode> <DataNode TextLabel="GRIN1" GraphId="f122f" Type="GeneProduct" GroupRef="e0d21"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14810</Comment> <Graphics CenterX="525.566407515387" CenterY="725.0" Width="103.13281503077422" Height="20.0" ZOrder="32862" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000176884" /> </DataNode> <DataNode TextLabel="CHL1" GraphId="a7e95" Type="GeneProduct" GroupRef="dea25"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000030077</Comment> <Graphics CenterX="534.75" CenterY="989.75" Width="210.5" Height="22.5" ZOrder="32864" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000134121" /> </DataNode> <DataNode TextLabel="CDH2" GraphId="a6857" Type="GeneProduct" GroupRef="beca5"> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12558</Comment> <Graphics CenterX="549.5" CenterY="614.0" Width="225.0" Height="20.0" ZOrder="32866" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSG00000170558" /> </DataNode> <DataNode TextLabel="ANK3" GraphId="b3775" Type="GeneProduct" GroupRef="dea25"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11735</Comment> <Graphics CenterX="671.0" CenterY="975.0" Width="78.0" Height="24.0" ZOrder="32868" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000151150" /> </DataNode> <DataNode TextLabel="CASK" GraphId="fcbf9" Type="GeneProduct" GroupRef="c8aa0"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031012</Comment> <Graphics CenterX="619.6728349315795" CenterY="869.3138553901282" Width="80.0" Height="20.0" ZOrder="32870" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000147044" /> </DataNode> <DataNode TextLabel="DAB1" GraphId="a7b26" Type="GeneProduct" GroupRef="e0d21"> <Comment>Validated target - predicted by bioinformatics</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000028519</Comment> <Graphics CenterX="548.7684375337442" CenterY="740.2723248029371" Width="32.35384947629826" Height="20.0" ZOrder="32872" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="Ensembl" ID="ENSG00000173406" /> </DataNode> <DataNode TextLabel="a-catenin&#xA;" GraphId="b7aca" Type="GeneProduct" GroupRef="beca5"> <Comment>Validated target - predicted by splicing microarray</Comment> <Graphics CenterX="696.0" CenterY="622.0" Width="80.0" Height="20.0" ZOrder="32874" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="LAR&#xA;" GraphId="b1f87" Type="GeneProduct" GroupRef="a4735"> <Comment>Validated target - predicted by splicing microarray</Comment> <Graphics CenterX="427.625" CenterY="565.75" Width="156.75" Height="20.0" ZOrder="32876" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="GRIK2" GraphId="b648e" Type="GeneProduct" GroupRef="a2684"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14806</Comment> <Graphics CenterX="470.0" CenterY="478.0" Width="80.0" Height="20.0" ZOrder="32878" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000164418" /> </DataNode> <DataNode TextLabel="CASK" GraphId="a3c42" Type="GeneProduct" GroupRef="a2684"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031012</Comment> <Graphics CenterX="540.0" CenterY="468.0" Width="80.0" Height="20.0" ZOrder="32880" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000147044" /> </DataNode> <DataNode TextLabel="PRKCZ" GraphId="d9629" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18762</Comment> <Graphics CenterX="643.6956889517834" CenterY="349.7573042287019" Width="80.0" Height="20.0" ZOrder="32882" FillColor="Transparent" FontSize="10" Valign="Middle" Color="3333ff" /> <Xref Database="Ensembl" ID="ENSG00000067606" /> </DataNode> <DataNode TextLabel="GABBR2" GraphId="a4e9e" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:242425</Comment> <Graphics CenterX="463.0" CenterY="301.0" Width="80.0" Height="20.0" ZOrder="32884" FillColor="Transparent" FontSize="10" Valign="Middle" Color="3333ff" /> <Xref Database="Ensembl" ID="ENSG00000136928" /> </DataNode> <DataNode TextLabel="nAChRa4" GraphId="d9f11" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Graphics CenterX="532.0" CenterY="122.0" Width="80.0" Height="20.0" ZOrder="32886" FillColor="Transparent" FontSize="10" Valign="Middle" Color="0066ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="PLCB4" GraphId="e9171" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000039943</Comment> <Graphics CenterX="77.0" CenterY="1136.0" Width="80.0" Height="18.0" ZOrder="32888" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000101333" /> </DataNode> <DataNode TextLabel="PIP2&#xA;" GraphId="f3406" Type="Metabolite"> <Graphics CenterX="110.5" CenterY="1098.5" Width="29.0" Height="13.0" ZOrder="32890" FontSize="10" Valign="Middle" /> <Xref Database="HMDB" ID="HMDB10032" /> </DataNode> <DataNode TextLabel="ANK3" GraphId="de9d2" Type="GeneProduct" GroupRef="e88a6"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11735</Comment> <Graphics CenterX="184.0" CenterY="1036.0" Width="78.0" Height="24.0" ZOrder="32892" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000151150" /> </DataNode> <DataNode TextLabel="ANK3" GraphId="e7176" Type="GeneProduct" GroupRef="d9b60"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11735</Comment> <Graphics CenterX="187.0" CenterY="975.0" Width="78.0" Height="24.0" ZOrder="32894" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000151150" /> </DataNode> <DataNode TextLabel="MAPK9" GraphId="dcd8b" Type="GeneProduct"> <Comment>Validated target - predicted by CLIP</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26420</Comment> <Graphics CenterX="85.0" CenterY="230.0" Width="80.0" Height="20.0" ZOrder="32896" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff00ff" /> <Xref Database="Ensembl" ID="ENSG00000050748" /> </DataNode> <DataNode TextLabel="EPB41" GraphId="b5ee6" Type="GeneProduct" GroupRef="ece36"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269587</Comment> <Graphics CenterX="146.4752726815035" CenterY="706.8631779512499" Width="80.00000000000003" Height="20.000000000000064" ZOrder="32898" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000159023" /> </DataNode> <DataNode TextLabel="EPB41" GraphId="f73ff" Type="GeneProduct" GroupRef="dba10"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269587</Comment> <Graphics CenterX="150.12901892926484" CenterY="750.7604856760055" Width="80.00000000000001" Height="19.99999999999994" ZOrder="32900" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000159023" /> </DataNode> <DataNode TextLabel="GRIK2" GraphId="dbdc8" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14806</Comment> <Graphics CenterX="223.0" CenterY="469.0" Width="80.0" Height="20.0" ZOrder="32902" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000164418" /> </DataNode> <DataNode TextLabel="KCNMA1" GraphId="a90b3" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16531</Comment> <Graphics CenterX="241.0" CenterY="307.0" Width="80.0" Height="20.0" ZOrder="32904" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000156113" /> </DataNode> <DataNode TextLabel="PRKCZ" GraphId="b6c02" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18762</Comment> <Graphics CenterX="84.0" CenterY="188.0" Width="80.0" Height="20.0" ZOrder="32906" FillColor="Transparent" FontSize="10" Valign="Middle" Color="0033ff" /> <Xref Database="Ensembl" ID="ENSG00000067606" /> </DataNode> <DataNode TextLabel="GABBR2" GraphId="e4b6e" Type="GeneProduct"> <Comment>CLIP predicted target</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:242425</Comment> <Graphics CenterX="164.0" CenterY="109.0" Width="80.0" Height="20.0" ZOrder="32908" FillColor="Transparent" FontSize="10" Valign="Middle" Color="0066ff" /> <Xref Database="Ensembl" ID="ENSG00000136928" /> </DataNode> <DataNode TextLabel="GPHN" GraphId="f550e" Type="GeneProduct" GroupRef="d7dd2"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:268566</Comment> <Graphics CenterX="611.0" CenterY="193.0" Width="80.0" Height="20.0" ZOrder="32910" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000171723" /> </DataNode> <DataNode TextLabel="PLCB4" GraphId="f6659" Type="GeneProduct"> <Comment>Validated target - predicted by splicing microarray</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000039943</Comment> <Graphics CenterX="552.751948168668" CenterY="327.5" Width="59.50389633733607" Height="17.0" ZOrder="32914" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="Ensembl" ID="ENSG00000101333" /> </DataNode> <DataNode TextLabel="EPB41L1" GraphId="f55c7" Type="GeneProduct" GroupRef="e2583"> <Comment>Validated target - predicted by bioinformatics</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13821</Comment> <Graphics CenterX="600.8414858006698" CenterY="807.2955404383973" Width="61.595939963286256" Height="18.638375985314752" ZOrder="32918" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="Ensembl" ID="ENSG00000088367" /> </DataNode> <DataNode TextLabel="CADM3" GraphId="cb609" Type="GeneProduct" GroupRef="e2583"> <Comment>Validated target - predicted by bioinformatics</Comment> <Comment Source="HomologyMapper">Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:94332</Comment> <Graphics CenterX="540.25" CenterY="816.75" Width="77.5" Height="20.5" ZOrder="32920" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="Ensembl" ID="ENSG00000162706" /> </DataNode> <DataNode TextLabel="Integrin a2&#xA;" GraphId="c907e" Type="GeneProduct" GroupRef="e0d21"> <Comment>Validated target - predicted by bioinformatics</Comment> <Graphics CenterX="506.74999999999926" CenterY="755.3357680762341" Width="108.5" Height="18.5" ZOrder="32923" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="validated target" GraphId="b1b99"> <Comment>Validated target</Comment> <Graphics CenterX="985.8333333333317" CenterY="117.66666666666612" Width="279.0" Height="20.0" ZOrder="32924" FillColor="Transparent" FontSize="10" Valign="Middle" Color="66cc00" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CLIP predicted target" GraphId="a8b97"> <Comment>CLIP predicted target</Comment> <Graphics CenterX="985.8333333333317" CenterY="148.66666666666623" Width="279.0" Height="20.0" ZOrder="32925" FillColor="Transparent" FontSize="10" Valign="Middle" Color="3333ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="validated target - predicted by bioinformatics" GraphId="d53e6"> <Comment>Validated target - predicted by bioinformatics</Comment> <Graphics CenterX="985.8333333333317" CenterY="181.6666666666666" Width="279.0" Height="20.0" ZOrder="32926" FillColor="Transparent" FontSize="10" Valign="Middle" Color="9900ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="validated target - predicted by splicing microarray" GraphId="d26de"> <Comment>Validated target - predicted by splicing microarray</Comment> <Graphics CenterX="985.8333333333317" CenterY="217.6666666666671" Width="279.0" Height="20.0" ZOrder="32927" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff6600" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="validated target - predicted by CLIP" GraphId="dbdf1"> <Comment>Validated target - predicted by CLIP</Comment> <Graphics CenterX="985.8333333333317" CenterY="253.66666666666748" Width="279.0" Height="20.0" ZOrder="32928" FillColor="Transparent" FontSize="10" Valign="Middle" Color="ff00ff" /> <Xref Database="" ID="" /> </DataNode> <Interaction GraphId="idc6058537"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="592.0" Y="473.0" GraphRef="e3a93" RelX="1.0" RelY="0.0" /> <Point X="610.0" Y="464.0" GraphRef="bf4ee" RelX="-1.0" RelY="0.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idd847fc44"> <Graphics ZOrder="12290" LineThickness="1.0"> <Point X="121.0" Y="163.0" GraphRef="fb864" RelX="-0.5" RelY="1.0" /> <Point X="104.0" Y="178.0" GraphRef="b6c02" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="ided7469df"> <Graphics ZOrder="12292" LineThickness="1.0"> <Point X="537.8759740843341" Y="336.0" GraphRef="f6659" RelX="-0.5" RelY="1.0" /> <Point X="500.75" Y="346.0" GraphRef="ad095" RelX="0.5" RelY="-1.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="ida025d4a3"> <Graphics ZOrder="12294" LineThickness="1.0"> <Point X="492.5" Y="359.0" GraphRef="ad095" RelX="0.0" RelY="1.0" /> <Point X="505.0" Y="385.0" GraphRef="b32d1" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idfcee9c43"> <Graphics ZOrder="12296" LineThickness="1.0"> <Point X="67.0" Y="1035.0" GraphRef="c9da6" RelX="0.0" RelY="-1.0" /> <Point X="65.0" Y="1012.0" GraphRef="d2221" RelX="0.0" RelY="1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idcb679b21"> <Graphics ZOrder="12298" LineThickness="1.0"> <Point X="84.0" Y="198.0" GraphRef="b6c02" RelX="0.0" RelY="1.0" /> <Point X="85.0" Y="220.0" GraphRef="dcd8b" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idc2223a0f"> <Graphics ZOrder="12300" LineThickness="1.0"> <Point X="125.0" Y="230.0" GraphRef="dcd8b" RelX="1.0" RelY="0.0" /> <Point X="191.0" Y="239.0" GraphRef="e77cc" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id195a8b23"> <Graphics ZOrder="12302" LineThickness="1.0"> <Point X="483.0" Y="311.0" GraphRef="a4e9e" RelX="0.5" RelY="1.0" /> <Point X="523.0" Y="327.5" GraphRef="f6659" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id4bdb89c5"> <Graphics ZOrder="12304" LineThickness="1.0"> <Point X="97.0" Y="1127.0" GraphRef="e9171" RelX="0.5" RelY="-1.0" /> <Point X="110.5" Y="1105.0" GraphRef="f3406" RelX="0.0" RelY="1.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idedbaaf37"> <Graphics ZOrder="12306" LineThickness="1.0"> <Point X="668.5915127955943" Y="673.5446496058747" GraphRef="e0a1c" RelX="0.0" RelY="1.0" /> <Point X="680.0" Y="700.0" GraphRef="c6a39" RelX="0.0" RelY="-1.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id47984a8e"> <Graphics ZOrder="12308" LineThickness="1.0"> <Point X="586.5" Y="592.0" GraphRef="bac4d" RelX="0.0" RelY="-1.0" /> <Point X="518.0" Y="569.5" GraphRef="d58fb" RelX="1.0" RelY="0.5" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id3b3b15bf"> <Graphics ZOrder="12310" LineThickness="1.0"> <Point X="117.75" Y="1092.0" GraphRef="f3406" RelX="0.5" RelY="-1.0" /> <Point X="175.0" Y="1074.0" GraphRef="aeede" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id43ddcbc8"> <Graphics ZOrder="12312" LineThickness="1.0"> <Point X="630.0" Y="454.0" GraphRef="bf4ee" RelX="-0.5" RelY="-1.0" /> <Point X="505.0" Y="405.0" GraphRef="b32d1" RelX="0.5" RelY="1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id4515b1dd"> <Graphics ZOrder="12314" LineThickness="1.0"> <Point X="164.0" Y="119.0" GraphRef="e4b6e" RelX="0.0" RelY="1.0" /> <Point X="141.0" Y="145.0" GraphRef="fb864" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idf610f4e6"> <Graphics ZOrder="12316" LineThickness="1.0"> <Point X="426.0" Y="138.0" GraphRef="f9841" RelX="1.0" RelY="0.0" /> <Point X="492.0" Y="122.0" GraphRef="d9f11" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id47b8cbc5"> <Graphics ZOrder="12318" LineThickness="1.0"> <Point X="582.5038963373361" Y="327.5" GraphRef="f6659" RelX="1.0" RelY="0.0" /> <Point X="603.6956889517834" Y="349.7573042287019" GraphRef="d9629" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id3ec4817"> <Graphics ZOrder="12320" LineThickness="1.0"> <Point X="176.5" Y="329.0" GraphRef="b2ff5" RelX="0.0" RelY="-1.0" /> <Point X="201.0" Y="307.0" GraphRef="a90b3" RelX="-1.0" RelY="0.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id619cdc0d"> <Graphics ZOrder="12322" LineThickness="1.0"> <Point X="694.0" Y="398.0" GraphRef="ab198" RelX="0.0" RelY="1.0" /> <Point X="650.0" Y="454.0" GraphRef="bf4ee" RelX="0.0" RelY="-1.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idfea68f2f"> <Graphics ZOrder="12324" LineThickness="1.0"> <Point X="443.0" Y="311.0" GraphRef="a4e9e" RelX="-0.5" RelY="1.0" /> <Point X="465.0" Y="385.0" GraphRef="b32d1" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idfaa643ec"> <Graphics ZOrder="12326" LineThickness="1.0"> <Point X="603.6956889517834" Y="349.7573042287019" GraphRef="d9629" RelX="-1.0" RelY="0.0" /> <Point X="525.0" Y="395.0" GraphRef="b32d1" RelX="1.0" RelY="0.0" ArrowHead="TBar" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="iddb8edeb9"> <Graphics ZOrder="12328" LineThickness="1.0"> <Point X="125.0" Y="575.0" GraphRef="d3e65" RelX="0.5" RelY="1.0" /> <Point X="210.02588949523533" Y="613.8252824002288" GraphRef="a40d4" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="idae41dfa5"> <Graphics ZOrder="12330" LineThickness="1.0"> <Point X="426.0" Y="138.0" GraphRef="f9841" RelX="1.0" RelY="0.0" /> <Point X="492.0" Y="153.0" GraphRef="a8f2f" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id25d17726"> <Graphics ZOrder="12334" LineThickness="1.0"> <Point X="667.25" Y="592.0" GraphRef="bac4d" RelX="0.5" RelY="-1.0" /> <Point X="548.5" Y="500.0" GraphRef="e3a93" RelX="0.5" RelY="1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id49ba6b4a"> <Graphics ZOrder="12336" LineThickness="1.0"> <Point X="124.0" Y="188.0" GraphRef="b6c02" RelX="1.0" RelY="0.0" /> <Point X="174.0" Y="188.0" GraphRef="c40fd" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Label TextLabel="Legend" GraphId="dd48b"> <Graphics CenterX="889.333333333333" CenterY="85.6666666666665" Width="80.0" Height="20.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" /> </Label> <Label TextLabel="PIP2&#xA;" GraphId="ec3b3"> <Graphics CenterX="401.0" CenterY="30.0" Width="0.0" Height="0.0" ZOrder="28672" FillColor="ffffff" FontSize="10" Valign="Middle" /> </Label> <Label TextLabel="Post-synaptic neuron&#xA;" GraphId="f610b"> <Graphics CenterX="606.5" CenterY="1230.0" Width="179.0" Height="36.0" ZOrder="28676" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" /> </Label> <Label TextLabel="PIP2" GraphId="c1e6b"> <Graphics CenterX="341.0" CenterY="207.0" Width="0.0" Height="0.0" ZOrder="28678" FillColor="ffffff" FontSize="10" Valign="Middle" /> </Label> <Label TextLabel="Pre-synaptic neuron&#xA;" GraphId="d321e"> <Graphics CenterX="123.5" CenterY="1227.0" Width="179.0" Height="36.0" ZOrder="32912" FillColor="ffffff" FontWeight="Bold" FontSize="14" Valign="Middle" /> </Label> <Shape GraphId="a9635"> <Graphics CenterX="611.793971121977" CenterY="619.6030972843903" Width="1097.4845828387859" Height="305.7488016047098" ZOrder="12332" FontSize="10" Valign="Middle" ShapeType="Arc" Rotation="1.5240959751164875" /> </Shape> <Shape GraphId="a74d6"> <Graphics CenterX="82.22245555673652" CenterY="617.1103115484881" Width="1087.6798006988965" Height="344.9047965840864" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Arc" Rotation="4.692819777197208" /> </Shape> <Shape GraphId="f69fc"> <Graphics CenterX="990.0833333333313" CenterY="179.0" Width="346.5" Height="240.0" ZOrder="16384" FontSize="10" Valign="Middle" ShapeType="Rectangle" Rotation="0.0" /> </Shape> <Group GroupId="d7dd2" GraphId="a1890" Style="Complex" /> <Group GroupId="e644e" GraphId="a40d4" Style="Complex" /> <Group GroupId="d2e54" GraphId="a5f94" Style="Complex" /> <Group GroupId="e88a6" GraphId="aeede" Style="Complex" /> <Group GroupId="b5b4b" GraphId="afb80" Style="Complex" /> <Group GroupId="e787b" GraphId="b2ff5" Style="Complex" /> <Group GroupId="c8aa0" GraphId="b43a6" Style="Complex" /> <Group GroupId="ece36" GraphId="b676d" Style="Complex" /> <Group GroupId="beca5" GraphId="bac4d" Style="Complex" /> <Group GroupId="e2583" GraphId="cb63a" Style="Complex" /> <Group GroupId="a4735" GraphId="d58fb" Style="Complex" /> <Group GroupId="d9b60" GraphId="de0fa" Style="Complex" /> <Group GroupId="c9e8e" GraphId="df8f0" Style="Complex" /> <Group GroupId="a2684" GraphId="e3a93" Style="Complex" /> <Group GroupId="dba10" GraphId="e472b" Style="Complex" /> <Group GroupId="dea25" GraphId="e6d7a" Style="Complex" /> <Group GroupId="b1604" GraphId="e77cc" Style="Complex" /> <Group GroupId="e0d21" GraphId="fe5d6" Style="Complex" /> <InfoBox CenterX="0.0" CenterY="0.0" /> <Biopax> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="ffd"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">16041372</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nova regulates brain-specific splicing to shape the synapse.</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nat Genet</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2005</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ule J</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ule A</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Spencer J</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Williams A</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hu JS</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cline M</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Wang H</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Clark T</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Fraser C</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ruggiu M</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Zeeberg BR</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Kane D</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Weinstein JN</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Blume J</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Darnell RB</bp:AUTHORS> </bp:PublicationXref> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="adb"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">17065982</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An RNA map predicting Nova-dependent splicing regulation.</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nature</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2006</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">J. Ule</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">G. Stefani</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A. Mele</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">M. Ruggiu</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">X. Wang</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">B. Taneri</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">T. Gaasterland</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">B.J. Blencowe</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">R.B. Darnell</bp:AUTHORS> </bp:PublicationXref> </Biopax> </Pathway>

• Template:AuthorInfo
• Template:CheckAvailable (protected)
• Template:PathwayPage:History
• Template:PathwayPage:Xrefs

Return to Splicing factor NOVA regulated synaptic proteins (Homo sapiens).