G protein signaling pathways (Bos taurus)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="G protein signaling pathways" Last-Modified="10/16/2013" Organism="Bos taurus"> <Comment Source="GenMAPP notes"/> <Comment Source="GenMAPP remarks"/> <Comment Source="WikiPathways-category">Cellular Process</Comment> <Comment Source="WikiPathways-description">G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They alternate from 'inactive' guanosine diphosphate (GDP) to 'active' guanosine triphosphate (GTP), which is a binding state, and which proceeds to regulate downstream cell processes. Source: [[wikipedia:G_protein|Wikipedia]]</Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://wikipathways.org/instance/WP35_r79952 WP35(79952)] with a 95.0% conversion rate.</Comment> <BiopaxRef>a06</BiopaxRef> <BiopaxRef>bb9</BiopaxRef> <Graphics BoardWidth="1073.0" BoardHeight="793.378"/> <DataNode TextLabel="PRKAR2B" GraphId="a05" Type="GeneProduct" GroupRef="e3e89"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5577</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR2B | protein kinase cAMP-dependent regul..."/> <Graphics CenterX="400.6666666666667" CenterY="543.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014958"/> </DataNode> <DataNode TextLabel="GNG10" GraphId="a3e" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2790</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG10 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="126.33333333333333" CenterY="372.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000009087"/> </DataNode> <DataNode TextLabel="PDE7B" GraphId="a4c" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:27115</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE7B | phosphodiesterase 7B"/> <Graphics CenterX="262.0" CenterY="606.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000015888"/> </DataNode> <DataNode TextLabel="ADCY3" GraphId="a4d" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:109</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY3 | adenylate cyclase 3"/> <Graphics CenterX="303.3333333333333" CenterY="300.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018705"/> </DataNode> <DataNode TextLabel="ADCY5" GraphId="a55" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:111</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY5 | adenylate cyclase 5"/> <Graphics CenterX="303.3333333333333" CenterY="340.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018777"/> </DataNode> <DataNode TextLabel="GNG12" GraphId="a5f" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55970</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG12 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="126.33333333333333" CenterY="412.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000035697"/> </DataNode> <DataNode TextLabel="GNG11" GraphId="a86" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2791</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG11 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="126.33333333333333" CenterY="392.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000000820"/> </DataNode> <DataNode TextLabel="AKAP8" GraphId="a8a" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10270</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP8 | A kinase (PRKA) anchor protein 8"/> <Graphics CenterX="43.333333333333336" CenterY="281.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000001807"/> </DataNode> <DataNode TextLabel="PPP3CC" GraphId="a9d" Type="GeneProduct" GroupRef="fdffe"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5533</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PPP3CC | protein phosphatase 3 (formerly 2B) c..."/> <Graphics CenterX="613.3333333333334" CenterY="464.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000020133"/> </DataNode> <DataNode TextLabel="AKAP1" GraphId="aa7" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8165</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP1 | A kinase (PRKA) anchor protein 1"/> <Graphics CenterX="43.333333333333336" CenterY="141.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000025320"/> </DataNode> <DataNode TextLabel="PRKAR1B" GraphId="ab3" Type="GeneProduct" GroupRef="e3e89"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5575</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR1B | protein kinase cAMP-dependent regul..."/> <Graphics CenterX="400.6666666666667" CenterY="503.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000046142"/> </DataNode> <DataNode TextLabel="GNAS" GraphId="ac0" Type="GeneProduct" GroupRef="ab002"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2778</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAS | GNAS complex locus"/> <Graphics CenterX="299.3333333333333" CenterY="80.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000017475"/> </DataNode> <DataNode TextLabel="PRKCD" GraphId="ac3" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5580</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCD | protein kinase C delta"/> <Graphics CenterX="834.3333333333334" CenterY="502.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000008719"/> </DataNode> <DataNode TextLabel="GNB3" GraphId="ae3" Type="GeneProduct" GroupRef="fe2ce"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2784</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB3 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="127.33333333333333" CenterY="165.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000016043"/> </DataNode> <DataNode TextLabel="PDE4A" GraphId="af7" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5141</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4A | phosphodiesterase 4A cAMP-specific (ph..."/> <Graphics CenterX="262.0" CenterY="506.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012032"/> </DataNode> <DataNode TextLabel="PDE1B" GraphId="afb" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5153</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE1B | phosphodiesterase 1B calmodulin-depend..."/> <Graphics CenterX="262.0" CenterY="466.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000004337"/> </DataNode> <DataNode TextLabel="GNAQ" GraphId="b03" Type="GeneProduct" GroupRef="f9b72"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2776</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAQ | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="723.3333333333334" CenterY="80.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000009789"/> </DataNode> <DataNode TextLabel="GNAO1" GraphId="b10" Type="GeneProduct" GroupRef="fc6c1"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2775</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAO1 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="426.0" CenterY="100.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000003794"/> </DataNode> <DataNode TextLabel="PDE4D" GraphId="b18" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5144</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4D | phosphodiesterase 4D cAMP-specific (ph..."/> <Graphics CenterX="262.0" CenterY="566.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000000494"/> </DataNode> <DataNode TextLabel="PRKCB" GraphId="b1c" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5579</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCB1 | protein kinase C beta 1"/> <Graphics CenterX="834.3333333333334" CenterY="462.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000020921"/> </DataNode> <DataNode TextLabel="RRAS" GraphId="b26" Type="GeneProduct" GroupRef="b7176"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6237</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RRAS | related RAS viral (r-ras) oncogene homol..."/> <Graphics CenterX="631.6666666666666" CenterY="331.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000020983"/> </DataNode> <DataNode TextLabel="GNA14" GraphId="b2f" Type="GeneProduct" GroupRef="f9b72"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9630</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNA14 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="723.3333333333334" CenterY="120.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000021127"/> </DataNode> <DataNode TextLabel="AKAP5" GraphId="b35" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9495</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP5 | A kinase (PRKA) anchor protein 5"/> <Graphics CenterX="43.333333333333336" CenterY="221.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000009642"/> </DataNode> <DataNode TextLabel="GNAZ" GraphId="b4c" Type="GeneProduct" GroupRef="fc6c1"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2781</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAZ | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="426.0" CenterY="120.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000047664"/> </DataNode> <DataNode TextLabel="ADCY4" GraphId="b5d" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:196883</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY4 | adenylate cyclase 4"/> <Graphics CenterX="303.3333333333333" CenterY="320.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018419"/> </DataNode> <DataNode TextLabel="PDE8B" GraphId="b8b" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8622</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE8B | phosphodiesterase 8B"/> <Graphics CenterX="262.0" CenterY="646.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000020205"/> </DataNode> <DataNode TextLabel="IP3" GraphId="bbbcf" Type="Metabolite"> <Graphics CenterX="723.3333333333334" CenterY="261.6666666666667" Width="28.0" Height="15.333333333333334" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="HMDB" ID="HMDB0001143"/> </DataNode> <DataNode TextLabel="NRAS" GraphId="bd1" Type="GeneProduct" GroupRef="b7176"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4893</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="NRAS | neuroblastoma RAS viral (v-ras) oncogene..."/> <Graphics CenterX="631.6666666666666" CenterY="291.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000046797"/> </DataNode> <DataNode TextLabel="GNG13" GraphId="bd7" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51764</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG13 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="126.33333333333333" CenterY="432.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000033526"/> </DataNode> <DataNode TextLabel="GNGT1" GraphId="bda" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2792</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNGT1 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="126.33333333333333" CenterY="232.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002674"/> </DataNode> <DataNode TextLabel="GNB2" GraphId="be4" Type="GeneProduct" GroupRef="fe2ce"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2783</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB2 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="127.33333333333333" CenterY="145.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000006495"/> </DataNode> <DataNode TextLabel="Ca2+" GraphId="bf55d" Type="Metabolite"> <Graphics CenterX="722.6666666666666" CenterY="379.6666666666667" Width="29.333333333333332" Height="14.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="HMDB" ID="HMDB0000464"/> </DataNode> <DataNode TextLabel="PRKAR1A" GraphId="bf6" Type="GeneProduct" GroupRef="e3e89"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5573</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR1A | protein kinase cAMP-dependent regul..."/> <Graphics CenterX="400.6666666666667" CenterY="483.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000008621"/> </DataNode> <DataNode TextLabel="DAG" GraphId="bfa4a" Type="Metabolite"> <Graphics CenterX="834.0" CenterY="260.3333333333333" Width="33.333333333333336" Height="15.333333333333334" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="KEGG Compound" ID="C00165"/> </DataNode> <DataNode TextLabel="GNA11" GraphId="bfb" Type="GeneProduct" GroupRef="f9b72"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2767</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNA11 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="723.3333333333334" CenterY="100.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012181"/> </DataNode> <DataNode TextLabel="PRKCH" GraphId="bff" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5583</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCH | protein kinase C eta"/> <Graphics CenterX="834.3333333333334" CenterY="562.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000003276"/> </DataNode> <DataNode TextLabel="PPP3CA" GraphId="c0f" Type="GeneProduct" GroupRef="fdffe"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5530</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PPP3CA | protein phosphatase 3 (formerly 2B) c..."/> <Graphics CenterX="613.3333333333334" CenterY="444.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000016005"/> </DataNode> <DataNode TextLabel="GNAI1" GraphId="c1d" Type="GeneProduct" GroupRef="fc6c1"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2770</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAI1 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="426.0" CenterY="140.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002714"/> </DataNode> <DataNode TextLabel="CALM1" GraphId="c4a" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Multiple homologues found: En:ENSBTAG00000001575;En:ENSBTAG00000025644;</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CALM1 | calmodulin 1 (phosphorylase kinase del..."/> <Graphics CenterX="723.3333333333334" CenterY="470.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PRKACB" GraphId="c56" Type="GeneProduct" GroupRef="e3e89"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5567</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKACB | protein kinase cAMP-dependent cataly..."/> <Graphics CenterX="400.6666666666667" CenterY="583.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000011953"/> </DataNode> <DataNode TextLabel="PRKAR2A" GraphId="c64" Type="GeneProduct" GroupRef="e3e89"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5576</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKAR2A | protein kinase cAMP-dependent regul..."/> <Graphics CenterX="400.6666666666667" CenterY="523.3333333333334" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014205"/> </DataNode> <DataNode TextLabel="GNB5" GraphId="c7e" Type="GeneProduct" GroupRef="fe2ce"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10681</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB5 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="127.33333333333333" CenterY="185.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000003762"/> </DataNode> <DataNode TextLabel="KCNJ3" GraphId="c9e" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3760</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="KCNJ3 | potassium inwardly-rectifying channel ..."/> <Graphics CenterX="487.3333333333333" CenterY="260.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000006159"/> </DataNode> <DataNode TextLabel="PLCB3" GraphId="cb9" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5331</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PLCB3 | phospholipase C beta 3 (phosphatidylin..."/> <Graphics CenterX="723.3333333333334" CenterY="196.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012510"/> </DataNode> <DataNode TextLabel="AKAP7" GraphId="cc3" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9465</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP7 | A kinase (PRKA) anchor protein 7"/> <Graphics CenterX="43.333333333333336" CenterY="261.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000000240"/> </DataNode> <DataNode TextLabel="GNA13" GraphId="cc5" Type="GeneProduct" GroupRef="e425c"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10672</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNA13 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="993.3333333333334" CenterY="100.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000046174"/> </DataNode> <DataNode TextLabel="ADCY6" GraphId="cd2" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:112</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY6 | adenylate cyclase 6"/> <Graphics CenterX="363.3333333333333" CenterY="260.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000005464"/> </DataNode> <DataNode TextLabel="AKAP3" GraphId="ce6" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10566</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP3 | A kinase (PRKA) anchor protein 3"/> <Graphics CenterX="43.333333333333336" CenterY="181.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000001020"/> </DataNode> <DataNode TextLabel="PDE1A" GraphId="d0f" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5136</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE1A | phosphodiesterase 1A calmodulin-depend..."/> <Graphics CenterX="262.0" CenterY="446.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012100"/> </DataNode> <DataNode TextLabel="PDE1C" GraphId="d17" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5137</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE1C | phosphodiesterase 1C calmodulin-depend..."/> <Graphics CenterX="262.0" CenterY="486.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002739"/> </DataNode> <DataNode TextLabel="ADCY2" GraphId="d21" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:108</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY2 | adenylate cyclase 2 (brain)"/> <Graphics CenterX="303.3333333333333" CenterY="280.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000019210"/> </DataNode> <DataNode TextLabel="GNAO1" GraphId="d2d" Type="GeneProduct" GroupRef="fc6c1"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2775</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAO1 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="426.0" CenterY="80.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000003794"/> </DataNode> <DataNode TextLabel="GNAL" GraphId="d32" Type="GeneProduct" GroupRef="ab002"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2774</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAL | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="299.3333333333333" CenterY="100.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002125"/> </DataNode> <DataNode TextLabel="PRKD1" GraphId="d33" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5587</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKD1 | protein kinase D1"/> <Graphics CenterX="834.3333333333334" CenterY="582.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000012789"/> </DataNode> <DataNode TextLabel="PRKD3" GraphId="d42" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23683</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKD3 | protein kinase D3"/> <Graphics CenterX="834.3333333333334" CenterY="602.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000001114"/> </DataNode> <DataNode TextLabel="ADCY9" GraphId="d55" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:115</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY9 | adenylate cyclase 9"/> <Graphics CenterX="363.3333333333333" CenterY="320.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000016629"/> </DataNode> <DataNode TextLabel="AKAP6" GraphId="d5f" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9472</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP6 | A kinase (PRKA) anchor protein 6"/> <Graphics CenterX="43.333333333333336" CenterY="241.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000017719"/> </DataNode> <DataNode TextLabel="ADCY1" GraphId="d79" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:107</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY1 | adenylate cyclase 1 (brain)"/> <Graphics CenterX="303.3333333333333" CenterY="260.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000009520"/> </DataNode> <DataNode TextLabel="PPP3CC" GraphId="d82" Type="GeneProduct" GroupRef="fdffe"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5533</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PPP3CC | protein phosphatase 3 (formerly 2B) c..."/> <Graphics CenterX="613.3333333333334" CenterY="484.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000020133"/> </DataNode> <DataNode TextLabel="AKAP13" GraphId="d86" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11214</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP13 | A kinase (PRKA) anchor protein 13"/> <Graphics CenterX="43.333333333333336" CenterY="381.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000037383"/> </DataNode> <DataNode TextLabel="GNA15" GraphId="d9d" Type="GeneProduct" GroupRef="f9b72"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2769</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNA15 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="723.3333333333334" CenterY="140.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000019988"/> </DataNode> <DataNode TextLabel="PDE8A" GraphId="dd9" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5151</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE8A | phosphodiesterase 8A"/> <Graphics CenterX="262.0" CenterY="626.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000015909"/> </DataNode> <DataNode TextLabel="AKAP12" GraphId="de0" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9590</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP12 | A kinase (PRKA) anchor protein (gravin..."/> <Graphics CenterX="43.333333333333336" CenterY="361.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014788"/> </DataNode> <DataNode TextLabel="RHOA" GraphId="de3" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:387</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RHOA | ras homolog gene family member A"/> <Graphics CenterX="993.3333333333334" CenterY="223.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000004279"/> </DataNode> <DataNode TextLabel="AKAP4" GraphId="e0c" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8852</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP4 | A kinase (PRKA) anchor protein 4"/> <Graphics CenterX="43.333333333333336" CenterY="201.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000016399"/> </DataNode> <DataNode TextLabel="GNAI3" GraphId="e18" Type="GeneProduct" GroupRef="fc6c1"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2773</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAI3 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="426.0" CenterY="180.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000013016"/> </DataNode> <DataNode TextLabel="AKAP11" GraphId="e39" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11215</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP11 | A kinase (PRKA) anchor protein 11"/> <Graphics CenterX="43.333333333333336" CenterY="341.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014752"/> </DataNode> <DataNode TextLabel="GNGT2" GraphId="e46" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2793</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNGT2 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="126.33333333333333" CenterY="252.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000047325"/> </DataNode> <DataNode TextLabel="PRKCQ" GraphId="e4d" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5588</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCQ | protein kinase C theta"/> <Graphics CenterX="834.3333333333334" CenterY="622.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000010664"/> </DataNode> <DataNode TextLabel="AKAP2" GraphId="e53" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Multiple homologues found: En:ENSBTAG00000014471;En:ENSBTAG00000014471;</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP2 | A kinase (PRKA) anchor protein 2"/> <Graphics CenterX="43.333333333333336" CenterY="161.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PDE4C" GraphId="e6d" Type="GeneProduct" GroupRef="e7c6e"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5143</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDE4C | phosphodiesterase 4C cAMP-specific (ph..."/> <Graphics CenterX="262.0" CenterY="546.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000010652"/> </DataNode> <DataNode TextLabel="GNG8" GraphId="e70" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:94235</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG8 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="126.33333333333333" CenterY="352.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000017762"/> </DataNode> <DataNode TextLabel="PRKCE" GraphId="e7b" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5581</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCE | protein kinase C epsilon"/> <Graphics CenterX="834.3333333333334" CenterY="522.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000020614"/> </DataNode> <DataNode TextLabel="GNG7" GraphId="e7d" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2788</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG7 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="126.33333333333333" CenterY="332.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000007644"/> </DataNode> <DataNode TextLabel="PRKCG" GraphId="e7f" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5582</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCG | protein kinase C gamma"/> <Graphics CenterX="834.3333333333334" CenterY="482.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000013550"/> </DataNode> <DataNode TextLabel="GNB1" GraphId="e8b" Type="GeneProduct" GroupRef="fe2ce"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2782</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNB1 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="127.33333333333333" CenterY="125.33333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000000215"/> </DataNode> <DataNode TextLabel="PRKCA" GraphId="ea5" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5578</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCA | protein kinase C alpha"/> <Graphics CenterX="834.3333333333334" CenterY="442.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000001061"/> </DataNode> <DataNode TextLabel="PRKCI" GraphId="eab" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5584</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCI | protein kinase C iota"/> <Graphics CenterX="834.3333333333334" CenterY="542.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000001403"/> </DataNode> <DataNode TextLabel="GNG5" GraphId="eae" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2787</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG5 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="126.33333333333333" CenterY="312.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000008122"/> </DataNode> <DataNode TextLabel="GNG3" GraphId="eb1" Type="GeneProduct" GroupRef="bb951"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2785</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNG3 | guanine nucleotide binding protein (G pr..."/> <Graphics CenterX="126.33333333333333" CenterY="272.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002508"/> </DataNode> <DataNode TextLabel="HRAS" GraphId="eb4" Type="GeneProduct" GroupRef="b7176"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3265</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="HRAS | v-Ha-ras Harvey rat sarcoma viral oncoge..."/> <Graphics CenterX="631.6666666666666" CenterY="271.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000046644"/> </DataNode> <DataNode TextLabel="PRKCZ" GraphId="ed7" Type="GeneProduct" GroupRef="deb28"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5590</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PRKCZ | protein kinase C zeta"/> <Graphics CenterX="834.3333333333334" CenterY="642.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014119"/> </DataNode> <DataNode TextLabel="ARHGEF1" GraphId="f06" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9138</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARHGEF1 | Rho guanine nucleotide exchange facto..."/> <Graphics CenterX="993.3333333333334" CenterY="160.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000018912"/> </DataNode> <DataNode TextLabel="cAMP" GraphId="f0a16" Type="Metabolite"> <Graphics CenterX="399.3333333333333" CenterY="419.0" Width="46.666666666666664" Height="15.333333333333334" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="HMDB" ID="HMDB0000058"/> </DataNode> <DataNode TextLabel="AKAP10" GraphId="f23" Type="GeneProduct" GroupRef="cada2"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11216</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKAP10 | A kinase (PRKA) anchor protein 10"/> <Graphics CenterX="43.333333333333336" CenterY="321.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000003439"/> </DataNode> <DataNode TextLabel="GNAI1" GraphId="f28" Type="GeneProduct" GroupRef="fc6c1"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2770</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GNAI1 | guanine nucleotide binding protein (G p..."/> <Graphics CenterX="426.0" CenterY="140.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000002714"/> </DataNode> <DataNode TextLabel="ADCY8" GraphId="f2b" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:114</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY8 | adenylate cyclase 8 (brain)"/> <Graphics CenterX="363.3333333333333" CenterY="300.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000014600"/> </DataNode> <DataNode TextLabel="ADCY7" GraphId="f4b" Type="GeneProduct" GroupRef="e3cf0"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:113</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ADCY7 | adenylate cyclase 7"/> <Graphics CenterX="363.3333333333333" CenterY="280.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSBTAG00000006208"/> </DataNode> <DataNode TextLabel="PRKACA" GraphId="f5a" Type="GeneProduct" GroupRef="e3e89"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5566</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" 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xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="a06"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">12040175</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">G protein pathways.</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Science</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2002</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Neves SR</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ram PT</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Iyengar R</bp:AUTHORS> </bp:PublicationXref> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" 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</bp:openControlledVocabulary> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">G protein mediated signaling pathway via Galphaq family</bp:TERM> <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000229</bp:ID> <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> </bp:openControlledVocabulary> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">G protein mediated signaling pathway via Galphai family</bp:TERM> <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000228</bp:ID> <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> </bp:openControlledVocabulary> </Biopax> </Pathway>

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