Globo sphingolipid metabolism (Homo sapiens)

From WikiPathways

You do not have permission to edit pages, for the following reasons:

• You do not have permission to edit pages in the Pathway namespace.
• You are not allowed to execute the action you have requested.

You can view and copy the source of this page:

<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Globo sphingolipid metabolism" Organism="Homo sapiens"> <Comment Source="WikiPathways-description">Globosides are a type of sphingolipids where a ceramide is linked to at least two sugars, however not to sialic acid. </Comment> <Comment Source="GenMAPP notes"/> <Comment Source="GenMAPP remarks"/> <Comment Source="WikiPathways-category">Metabolic Process</Comment> <BiopaxRef>fab</BiopaxRef> <Graphics BoardWidth="1186.57894736842" BoardHeight="582.7853107344635"/> <DataNode TextLabel="ST6GALNAC3" GraphId="a0674" Type="GeneProduct" GroupRef="c8a85"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GALNAC3"/> <Graphics CenterX="399.7457627118645" CenterY="517.7853107344635" Width="80.0" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000184005"/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="a139e" Type="Metabolite"> <Graphics CenterX="1111.57894736842" CenterY="247.98333333333332" Width="90.0" Height="25.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Forssman Antigen Synthase" GraphId="a3cfa" Type="GeneProduct"> <Comment Source="GenMAPP remarks">2.4.1.88</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="A3GalNT"/> <Graphics CenterX="477.0438596491232" CenterY="114.22696954025238" Width="173.35087719298218" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Uniprot-TrEMBL" ID="Q8N5D6"/> </DataNode> <DataNode TextLabel="ST6GALNAC4" GraphId="a5409" Type="GeneProduct" GroupRef="c8a85"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GALNAC4"/> <Graphics CenterX="479.7457627118645" CenterY="494.4519774011301" Width="80.0" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000136840"/> </DataNode> <DataNode TextLabel="Globo H" GraphId="a7055" Type="Metabolite"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Globo H"/> <Graphics CenterX="413.48333333333335" CenterY="247.98333333333332" Width="40.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="HMDB" ID="HMDB0004963"/> </DataNode> <DataNode TextLabel="FUT1" GraphId="a705e" Type="GeneProduct" GroupRef="edbac"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="FUT1"/> <Graphics CenterX="481.4982231698669" CenterY="193.76403695806678" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000174951"/> </DataNode> <DataNode TextLabel="Gb4" GraphId="aaa79" Type="Metabolite"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Gb4"/> <Graphics CenterX="604.4833333333333" CenterY="153.98333333333332" Width="40.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0033ff"/> <Xref Database="HMDB" ID="HMDB0004960"/> </DataNode> <DataNode TextLabel="ST6GALNAC5" GraphId="ac3ff" Type="GeneProduct" GroupRef="c8a85"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GALNAC5"/> <Graphics CenterX="479.7457627118645" CenterY="517.7853107344635" Width="80.0" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000117069"/> </DataNode> <DataNode TextLabel="FUT2" GraphId="af738" Type="GeneProduct" GroupRef="edbac"> <Comment Source="GenMAPP remarks">2.4.1.69</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="FUT2"/> <Graphics CenterX="481.4982231698669" CenterY="213.76403695806678" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000176920"/> </DataNode> <DataNode TextLabel="FUT9" GraphId="b0141" Type="GeneProduct"> <Comment Source="GenMAPP remarks">2.4.1.152</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="FUT9"/> <Graphics CenterX="1008.4561403508766" CenterY="205.07017543859644" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000172461"/> </DataNode> <DataNode TextLabel="B3GALT5" GraphId="b5db2" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="B3GALT5"/> <Graphics CenterX="553.8889200613471" CenterY="196.4651180189279" Width="53.777840122694215" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000183778"/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="b678a" Type="Metabolite"> <Graphics CenterX="333.135593220339" CenterY="372.3898305084746" Width="90.0" Height="25.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="b7a36" Type="Metabolite"> <Graphics CenterX="604.4833333333333" CenterY="458.94915254237344" Width="90.0" Height="25.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="Hexosyltransferases" GraphId="bcf3a" Type="GeneProduct"> <Comment Source="GenMAPP remarks">2.4.1.-</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="2.4.1.-"/> <Graphics CenterX="816.122807017544" CenterY="214.07017543859646" Width="120.70175438596478" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Enzyme Nomenclature" ID="2.4.1.-"/> </DataNode> <DataNode TextLabel="ST6GALNAC2" GraphId="c027e" Type="GeneProduct" GroupRef="c8a85"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GALNAC2"/> <Graphics CenterX="399.7457627118645" CenterY="541.1186440677967" Width="80.0" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000070731"/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="c0c96" Type="Metabolite"> <Graphics CenterX="778.9473684210527" CenterY="247.98333333333332" Width="90.0" Height="25.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="SSEA-3" GraphId="c12f5" Type="Metabolite"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SSEA3"/> <Graphics CenterX="604.4833333333333" CenterY="247.98333333333332" Width="40.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="HMDB" ID="HMDB0004962"/> </DataNode> <DataNode TextLabel="LacCer" GraphId="c75e4" Type="Metabolite"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="LacCer"/> <Graphics CenterX="465.48333333333335" CenterY="48.42105263157896" Width="40.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0033ff"/> <Xref Database="HMDB" ID="HMDB0006750"/> </DataNode> <DataNode TextLabel="ST6GAL2" GraphId="cae84" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GAL2"/> <Graphics CenterX="789.3157894736845" CenterY="424.28070175438586" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000144057"/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="cc380" Type="Metabolite"> <Graphics CenterX="925.2631578947368" CenterY="247.98333333333332" Width="90.0" Height="25.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="A4GALT" GraphId="d0e64" Type="GeneProduct"> <Comment Source="GenMAPP remarks">2.4.1.228</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="A4galT"/> <Graphics CenterX="529.735607675907" CenterY="19.08599857853587" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000128274"/> </DataNode> <DataNode TextLabel="ST8SIA1" GraphId="d4430" Type="GeneProduct"> <Comment Source="GenMAPP remarks">2.4.99.8</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST8Sia1"/> <Graphics CenterX="548.7966101694913" CenterY="413.6440677966102" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000111728"/> </DataNode> <DataNode TextLabel="ST6GALNAC6" GraphId="d5944" Type="GeneProduct" GroupRef="c8a85"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GALNAC6"/> <Graphics CenterX="479.7457627118645" CenterY="541.1186440677967" Width="80.0" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000160408"/> </DataNode> <DataNode TextLabel="ST3GAL2" GraphId="d6aef" Type="GeneProduct" GroupRef="d0ad0"> <Comment Source="GenMAPP remarks">2.4.99.4</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST3GAL2"/> <Graphics CenterX="676.0980810234521" CenterY="316.66666666666663" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000157350"/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="d954e" Type="Metabolite"> <Graphics CenterX="775.7894736842109" CenterY="48.42105263157896" Width="90.0" Height="25.0" ZOrder="32768" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="ST6GALNAC1" GraphId="d95d5" Type="GeneProduct" GroupRef="c8a85"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GALNAC1"/> <Graphics CenterX="399.7457627118645" CenterY="494.45197740113014" Width="80.0" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000070526"/> </DataNode> <DataNode TextLabel="ST3GAL1" GraphId="e0024" Type="GeneProduct" GroupRef="d0ad0"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST3GAL1"/> <Graphics CenterX="676.0980810234521" CenterY="293.3333333333333" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000008513"/> </DataNode> <DataNode TextLabel="GALNT2" GraphId="e0a06" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GALNT2"/> <Graphics CenterX="706.140350877193" CenterY="123.15789473684208" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000143641"/> </DataNode> <DataNode TextLabel="ABO" GraphId="e5db1" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ABO"/> <Graphics CenterX="326.3333333333333" CenterY="263.66666666666663" Width="40.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000175164"/> </DataNode> <DataNode TextLabel="Globoside Synthase" GraphId="e8918" Type="Protein"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="B3GALNT1"/> <Graphics CenterX="694.8166311300629" CenterY="94.20113717128642" Width="135.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Uniprot-TrEMBL" ID="O75752"/> </DataNode> <DataNode TextLabel="SSEA-4" GraphId="eb937" Type="Metabolite"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SSEA-4"/> <Graphics CenterX="604.4833333333333" CenterY="372.3898305084746" Width="40.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="ST6GAL1" GraphId="ed3e8" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ST6GAL1"/> <Graphics CenterX="697.2105263157895" CenterY="425.122807017544" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000073849"/> </DataNode> <DataNode TextLabel="Gb3" GraphId="f251f" Type="Metabolite"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="Gb3"/> <Graphics CenterX="603.4833333333333" CenterY="48.42105263157896" Width="40.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0033ff"/> <Xref Database="HMDB" ID="HMDB0004879"/> </DataNode> <DataNode TextLabel="A3GALT2" GraphId="fd57d" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="A3GALT2"/> <Graphics CenterX="667.7192982456136" CenterY="19.08599857853587" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000128274"/> </DataNode> <DataNode TextLabel="ABO" GraphId="fe1ae" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ABO"/> <Graphics CenterX="326.3333333333333" CenterY="229.33333333333334" Width="40.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000175164"/> </DataNode> <DataNode TextLabel="GCNT1" GraphId="fe893" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GCNT1"/> <Graphics CenterX="668.5614035087718" CenterY="216.70175438596488" Width="66.66666666666667" Height="23.333333333333332" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Ensembl" ID="ENSG00000187210"/> </DataNode> <DataNode TextLabel="Metabolite" GraphId="e3f52" Type="Metabolite"> <Graphics CenterX="853.157894736842" CenterY="372.3898305084746" Width="90.0" Height="25.0" ZOrder="32770" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <Interaction GraphId="a5e06"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="604.4833333333333" Y="267.98333333333335" GraphRef="c12f5" RelX="0.0" RelY="1.0"/> <Point X="604.4833333333333" Y="352.3898305084746" GraphRef="eb937" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/> <Anchor Position="0.4489790403036778" Shape="None" GraphId="d86a1"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="ad81e"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="485.48333333333335" Y="48.42105263157896" GraphRef="c75e4" RelX="1.0" RelY="0.0"/> <Point X="583.4833333333333" Y="48.42105263157896" GraphRef="f251f" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4423382846167984" Shape="None" GraphId="c0bdd"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="c0690"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="604.4833333333333" Y="173.98333333333332" GraphRef="aaa79" RelX="0.0" RelY="1.0"/> <Point X="604.4833333333333" Y="227.98333333333335" GraphRef="c12f5" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/> <Anchor Position="0.4262345679012346" Shape="None" GraphId="d4475"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="c11f7"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="306.3333333333333" Y="263.66666666666663" GraphRef="e5db1" RelX="-1.0" RelY="0.0"/> <Point X="284.9758620612397" Y="263.72751985784566" GraphRef="acf94" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="c8815"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="823.9473684210527" Y="247.98333333333335" GraphRef="c0c96" RelX="1.0" RelY="0.0"/> <Point X="880.2631578947368" Y="247.98333333333335" GraphRef="cc380" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="c76eb"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="cabe6"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="624.4833333333333" Y="247.98333333333335" GraphRef="c12f5" RelX="1.0" RelY="0.0"/> <Point X="733.9473684210527" Y="247.98333333333335" GraphRef="c0c96" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="d0dc4"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="cef9b"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="604.4833333333333" Y="392.3898305084746" GraphRef="eb937" RelX="0.0" RelY="1.0"/> <Point X="604.4833333333333" Y="446.44915254237344" GraphRef="b7a36" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="d4621"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="cf5e7"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="624.4833333333333" Y="372.3898305084746" GraphRef="eb937" RelX="1.0" RelY="0.0"/> <Point X="808.157894736842" Y="372.3898305084746" GraphRef="e3f52" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="e3c33"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="d225e"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="970.2631578947368" Y="247.98333333333335" GraphRef="cc380" RelX="1.0" RelY="0.0"/> <Point X="1066.57894736842" Y="247.98333333333335" GraphRef="a139e" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="b4771"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="dbb9d"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="584.4833333333333" Y="247.98333333333335" GraphRef="c12f5" RelX="-1.0" RelY="0.0"/> <Point X="433.48333333333335" Y="247.98333333333335" GraphRef="a7055" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.6786975717439294" Shape="None" GraphId="fe84a"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="e2136"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="584.4833333333333" Y="372.3898305084746" GraphRef="eb937" RelX="-1.0" RelY="0.0"/> <Point X="378.135593220339" Y="372.3898305084746" GraphRef="b678a" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.7001934368373283" Shape="None" GraphId="fb7bc"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="e31ae"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="306.3333333333333" Y="229.33333333333334" GraphRef="fe1ae" RelX="-1.0" RelY="0.0"/> <Point X="284.84210177692927" Y="229.5158929068703" GraphRef="d8b5d" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="e449d"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="584.4833333333333" Y="153.98333333333332" GraphRef="aaa79" RelX="-1.0" RelY="0.0"/> <Point X="350.69303061091784" Y="153.83058174536905" GraphRef="c767b" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.45973664676782083" Shape="None" GraphId="d4726"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="f6726"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="603.4833333333333" Y="68.42105263157896" GraphRef="f251f" RelX="0.0" RelY="1.0"/> <Point X="604.4833333333333" Y="133.98333333333332" GraphRef="aaa79" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="feb88"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="f8e9f"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="624.4833333333333" Y="153.98333333333332" GraphRef="aaa79" RelX="1.0" RelY="0.0"/> <Point X="829.7324245614036" Y="153.94736842105266" GraphRef="a0454" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="e9e3b"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="fc100"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="623.4833333333333" Y="48.42105263157896" GraphRef="f251f" RelX="1.0" RelY="0.0"/> <Point X="730.7894736842109" Y="48.42105263157896" GraphRef="d954e" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/> <Anchor Position="0.4" Shape="None" GraphId="c4c31"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id2a12d34"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="529.735607675907" Y="30.752665245202536" GraphRef="d0e64" RelX="0.0" RelY="1.0"/> <Point X="528.8324852257796" Y="48.42105263157896" GraphRef="c0bdd" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id3592589f"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="634.7647476901188" Y="304.99999999999994" GraphRef="e3ae9" RelX="-1.0" RelY="0.0"/> <Point X="604.4833333333333" Y="305.88008143042333" GraphRef="d86a1" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id569f9608"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="667.7192982456136" Y="30.752665245202536" GraphRef="fd57d" RelX="0.0" RelY="1.0"/> <Point X="666.4057894736843" Y="48.42105263157896" GraphRef="c4c31" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id730f225e"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="706.140350877193" Y="134.82456140350874" GraphRef="e0a06" RelX="0.0" RelY="1.0"/> <Point X="706.5829698245615" Y="153.96894736842106" GraphRef="e9e3b" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id75c60d20"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="668.5614035087717" Y="228.36842105263156" GraphRef="fe893" RelX="0.0" RelY="1.0"/> <Point X="668.2689473684211" Y="247.98333333333335" GraphRef="d0dc4" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id87dd457b"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="846.2982456140353" Y="225.73684210526318" GraphRef="bcf3a" RelX="0.5" RelY="1.0"/> <Point X="846.4736842105264" Y="247.98333333333335" GraphRef="c76eb" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id9713cdf1"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="477.0438596491232" Y="125.89363620691904" GraphRef="a3cfa" RelX="0.0" RelY="1.0"/> <Point X="477.0013635128963" Y="153.91310783049417" GraphRef="d4726" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id9beb2df0"> <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0"> <Point X="346.3333333333333" Y="263.66666666666663" GraphRef="e5db1" RelX="1.0" RelY="0.0"/> <Point X="393.48333333333335" Y="247.98333333333335" GraphRef="a7055" RelX="-1.0" RelY="0.0"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="id9c4de670"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="627.3166311300629" Y="94.20113717128642" GraphRef="e8918" RelX="-1.0" RelY="0.0"/> <Point X="603.8833333333333" Y="94.6459649122807" GraphRef="feb88" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idb5ae3da6"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="481.49822316986695" Y="231.76403695806678" GraphRef="cfbeb" RelX="0.0" RelY="1.0"/> <Point X="482.0" Y="247.98333333333335" GraphRef="fe84a" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idbceb247e"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="582.1299435028245" Y="413.6440677966102" GraphRef="d4430" RelX="1.0" RelY="0.0"/> <Point X="604.4833333333333" Y="414.0135593220341" GraphRef="d4621" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idd1d9a650"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="439.7457627118645" Y="474.78531073446345" GraphRef="f4d3f" RelX="0.0" RelY="-1.0"/> <Point X="440.0" Y="372.3898305084746" GraphRef="fb7bc" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="idd48c32bb"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="580.7778401226942" Y="196.4651180189279" GraphRef="b5db2" RelX="1.0" RelY="0.0"/> <Point X="604.4833333333333" Y="197.0" GraphRef="d4475" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="iddff47473"> <Graphics ConnectorType="Elbow" ZOrder="12288" LineThickness="1.0"> <Point X="346.3333333333333" Y="229.33333333333334" GraphRef="fe1ae" RelX="1.0" RelY="0.0"/> <Point X="393.48333333333335" Y="247.98333333333335" GraphRef="a7055" RelX="-1.0" RelY="0.0"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="ided77764d"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="697.2105263157894" Y="413.4561403508774" GraphRef="ed3e8" RelX="0.0" RelY="-1.0"/> <Point X="697.9531578947368" Y="372.3898305084746" GraphRef="e3c33" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="c1100"> <Graphics ZOrder="32769" LineThickness="1.0"> <Point X="1008.4561403508766" Y="216.73684210526312" GraphRef="b0141" RelX="0.0" RelY="1.0"/> <Point X="1008.7894736842101" Y="247.98333333333335" GraphRef="b4771" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Interaction GraphId="ede9f"> <Graphics ZOrder="32771" LineThickness="1.0"> <Point X="789.3157894736844" Y="412.61403508771923" GraphRef="cae84" RelX="0.0" RelY="-1.0"/> <Point X="697.9531578947368" Y="372.3898305084746" GraphRef="e3c33" RelX="0.0" RelY="0.0" ArrowHead="mim-catalysis"/> </Graphics> <Xref Database="" ID=""/> </Interaction> <Label TextLabel="Para-Forssman Antigen" GraphId="a0454"> <Graphics CenterX="927.4977912280702" CenterY="153.94736842105266" Width="195.53073333333322" Height="18.391666666666666" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/> </Label> <Label TextLabel="Type IV B Antigen" GraphId="acf94"> <Graphics CenterX="214.61762872790638" CenterY="263.72751985784566" Width="140.71646666666666" Height="18.391666666666666" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/> </Label> <Label TextLabel="Forssman Antigen" GraphId="c767b"> <Graphics CenterX="278.4956306109179" CenterY="153.83058174536902" Width="144.3948" Height="18.391666666666666" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/> </Label> <Label TextLabel="Type IV A Antigen" GraphId="d8b5d"> <Graphics CenterX="214.7393351102626" CenterY="229.51589290687028" Width="140.20553333333334" Height="18.391666666666666" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/> </Label> <Group GroupId="edbac" GraphId="cfbeb" Style="Group"/> <Group GroupId="d0ad0" GraphId="e3ae9" Style="Group"/> <Group GroupId="c8a85" GraphId="f4d3f" Style="Group"/> <InfoBox CenterX="0.0" CenterY="0.0"/> <Biopax> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="fab"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">29165427</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sphingolipids and their metabolism in physiology and disease.</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nat Rev Mol Cell Biol</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2018</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hannun YA</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Obeid LM</bp:AUTHORS> </bp:PublicationXref> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">classic metabolic pathway</bp:TERM> <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000002</bp:ID> <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> </bp:openControlledVocabulary> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">sphingolipid metabolic pathway</bp:TERM> <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000197</bp:ID> <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> </bp:openControlledVocabulary> <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">globoside metabolic pathway</bp:TERM> <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000196</bp:ID> <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> </bp:openControlledVocabulary> </Biopax> </Pathway>

Return to Globo sphingolipid metabolism (Homo sapiens).