Tetrahydrofolate biosynthesis II (Oryza sativa)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Tetrahydrofolate biosynthesis II" Data-Source="Plant Reactome - http://plantreactome.gramene.org" Version="43" Maintainer="Amoss, Kindra" Organism="Oryza sativa"> <Comment Source="WikiPathways-description">Developed by Gramene.org Source:[http://plantreactome.gramene.org/ Plant Reactome].</Comment> <Attribute Key="reactome_id" Value="1119523"/> <Graphics BoardWidth="1181.0" BoardHeight="1482.0"/> <DataNode TextLabel="7,8-dihydroneopterin&#10;3'-triphosphate" GraphId="ff844" Type="Metabolite"> <Attribute Key="reactome_id" Value="1132020"/> <Graphics CenterX="915.5" CenterY="190.5" Width="139.0" Height="55.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:18372"/> </DataNode> <DataNode TextLabel="GTP cyclohydrolase I&#10; (LOC_OS04G56710.1)" GraphId="d66c6" Type="Protein"> <Comment Source="Reactome">Facilitates the conversion of GTP to 7,8-dihydroneopterin 3'-triphosphate.</Comment> <Attribute Key="reactome_id" Value="1127241"/> <Graphics CenterX="1032.0" CenterY="118.0" Width="146.0" Height="64.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Uniprot-TrEMBL" ID="Q0J9B5"/> </DataNode> <DataNode TextLabel="dihydroneopterin&#10;phosphate" GraphId="a40ff" Type="Metabolite"> <Attribute Key="reactome_id" Value="1132178"/> <Graphics CenterX="915.0" CenterY="333.0" Width="120.0" Height="58.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:48954"/> </DataNode> <DataNode TextLabel="dihydroneopterin" GraphId="aba48" Type="Metabolite"> <Attribute Key="reactome_id" Value="1130901"/> <Graphics CenterX="915.0" CenterY="450.0" Width="134.0" Height="44.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:17001"/> </DataNode> <DataNode TextLabel="glycolaldehyde" GraphId="a857d" Type="Metabolite"> <Attribute Key="reactome_id" Value="1132263"/> <Graphics CenterX="801.0" CenterY="517.0" Width="106.0" Height="40.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:17071"/> </DataNode> <DataNode TextLabel="" GraphId="bcbff" Type="Metabolite"> <Graphics CenterX="0.0" CenterY="0.0" Width="0.0" Height="0.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="dihydroneopterin&#10;aldolase" GraphId="e410f" Type="Protein"> <Comment Source="Reactome">Facilitates the conversion of dihydro-neo-pterin to 6-hydroxymethyl-dihydropterin.</Comment> <Attribute Key="reactome_id" Value="1121856"/> <Graphics CenterX="1025.0" CenterY="495.0" Width="112.0" Height="36.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Reactome" ID="1121856"/> </DataNode> <DataNode TextLabel="2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine&#10;diphosphate" GraphId="d3419" Type="Metabolite"> <Attribute Key="reactome_id" Value="1131536"/> <Graphics CenterX="915.5" CenterY="712.0" Width="135.0" Height="100.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:15998"/> </DataNode> <DataNode TextLabel="2-amino-4-hydroxy-6-hydroxymethyldihydropteridine&#10;diphosphokinase" GraphId="bc596" Type="Protein"> <Comment Source="Reactome">Facilitates the conversion of 6-hydroxymethyl-dihydropterin to 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate.</Comment> <Attribute Key="reactome_id" Value="1121789"/> <Graphics CenterX="1038.5" CenterY="624.0" Width="157.0" Height="66.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Reactome" ID="1121789"/> </DataNode> <DataNode TextLabel="7,8-dihydropteroate" GraphId="ad487" Type="Metabolite"> <Attribute Key="reactome_id" Value="1131783"/> <Graphics CenterX="740.5" CenterY="845.0" Width="131.0" Height="44.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:4581"/> </DataNode> <DataNode TextLabel="dihydropteroate&#10;synthase" GraphId="a1327" Type="Protein"> <Comment Source="Reactome">Facilitates the combination of p-aminobenzoate and 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate to form 7,8-dihydropteroate.</Comment> <Attribute Key="reactome_id" Value="1121951"/> <Graphics CenterX="1025.0" CenterY="782.0" Width="112.0" Height="36.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Reactome" ID="1121951"/> </DataNode> <DataNode TextLabel="4-amino-4-deoxychorismate" GraphId="c6ad3" Type="Metabolite"> <Attribute Key="reactome_id" Value="1131074"/> <Graphics CenterX="578.0" CenterY="612.0" Width="128.0" Height="58.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:18198"/> </DataNode> <DataNode TextLabel="dihydrofolate&#10;reductase" GraphId="d873a" Type="Protein"> <Comment Source="Reactome">Facilitates the conversion of 7,8-dihydrofolate to tetrahydrofolate.</Comment> <Attribute Key="reactome_id" Value="1121824"/> <Graphics CenterX="850.0" CenterY="1062.0" Width="96.0" Height="50.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Reactome" ID="1121824"/> </DataNode> <DataNode TextLabel="" GraphId="ed59d" Type="Metabolite"> <Graphics CenterX="0.0" CenterY="0.0" Width="0.0" Height="0.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="" GraphId="e051a" Type="Metabolite"> <Graphics CenterX="0.0" CenterY="0.0" Width="0.0" Height="0.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="" GraphId="df04b" Type="Metabolite"> <Graphics CenterX="0.0" CenterY="0.0" Width="0.0" Height="0.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="formate--tetrahydrofolate&#10;ligase&#10;(LOC_OS09G27420.1)" GraphId="e6902" Type="Protein"> <Comment Source="Reactome">Catalyzes the convertion of tetrahydrofolate into N10-formyl-THF.</Comment> <Attribute Key="reactome_id" Value="1126542"/> <Graphics CenterX="311.5" CenterY="1231.5" Width="137.0" Height="63.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Uniprot-TrEMBL" ID="Q0J1E1"/> </DataNode> <DataNode TextLabel="tetrahydrofolate&#10;synthase" GraphId="d56d1" Type="Protein"> <Comment Source="Reactome">Catalyzes the convertion of tetrahydropteroyl-[gamma-Glu](n) into tetrahydropteroyl-[gamma-Glu](n+1).</Comment> <Attribute Key="reactome_id" Value="1121701"/> <Graphics CenterX="703.0" CenterY="1251.0" Width="112.0" Height="36.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Reactome" ID="1121701"/> </DataNode> <DataNode TextLabel="" GraphId="a3dcb" Type="Metabolite"> <Graphics CenterX="0.0" CenterY="0.0" Width="0.0" Height="0.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="GTP" GraphId="a2009" Type="Metabolite"> <Attribute Key="reactome_id" Value="29438"/> <Graphics CenterX="915.5" CenterY="56.5" Width="55.0" Height="29.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:15996"/> </DataNode> <DataNode TextLabel="H2O" GraphId="ff911" Type="Metabolite"> <Attribute Key="reactome_id" Value="29356"/> <Graphics CenterX="801.5" CenterY="92.0" Width="49.0" Height="32.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:15377"/> </DataNode> <DataNode TextLabel="HCOOH" GraphId="d96fe" Type="Metabolite"> <Attribute Key="reactome_id" Value="29460"/> <Graphics CenterX="801.0" CenterY="144.5" Width="76.0" Height="33.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff"/> <Xref Database="ChEBI" ID="CHEBI:30751"/> </DataNode> <DataNode TextLabel="H2O" 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