Alanine and aspartate metabolism (Bos taurus)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Alanine and aspartate metabolism" Organism="Bos taurus" License="CC BY 2.0"> <Comment Source="WikiPathways-description">Originally based on KEGG: http://www.genome.ad.jp/dbget-bin/show pathway?rno00252 Edited by Sebastien Burel.</Comment> <Comment Source="WikiPathways-category">Metabolic Process</Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://wikipathways.org/instance/WP106_r74147 WP106(74147)] with a 29.0% conversion rate.</Comment> <BiopaxRef>e65</BiopaxRef> <BiopaxRef>f1b</BiopaxRef> <Graphics BoardWidth="1333.6666666666667" BoardHeight="1243.0" /> <DataNode TextLabel="Fatty acid metabolism" GraphId="d5a97" Type="Pathway"> <Graphics CenterX="460.0" CenterY="553.3333333333334" Width="129.33333333333334" Height="15.0" ZOrder="28672" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="14961e" /> <Xref Database="WikiPathways" ID="WP143" /> </DataNode> <DataNode TextLabel="Pyruvate" GraphId="a3720" Type="Metabolite"> <Graphics CenterX="535.2380952380954" CenterY="235.95238095238102" Width="80.0" Height="14.761904761904706" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="ChEBI" ID="CHEBI:32816" /> </DataNode> <DataNode TextLabel="3.5.1.3" GraphId="a3a" Type="GeneProduct"> <Graphics CenterX="421.3333333333333" CenterY="1020.6666666666666" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="GOT2" GraphId="a43" Type="GeneProduct" GroupRef="b134d"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2806</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GOT2 | glutamic-oxaloacetic transaminase 2 mit..." /> <Graphics CenterX="462.66666666666663" CenterY="851.0" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000007172" /> </DataNode> <DataNode TextLabel="3.4.13.3" GraphId="a77" Type="GeneProduct"> <Graphics CenterX="793.0" CenterY="544.3333333333333" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="L-Alanine" GraphId="ab0" Type="Metabolite"> <Graphics CenterX="936.0" CenterY="235.66666666666666" Width="58.333333333333336" Height="15.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="ChEBI" ID="CHEBI:16977" /> </DataNode> <DataNode TextLabel="ASL" GraphId="ac6" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:435</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ASL | argininosuccinate lyase" /> <Graphics CenterX="1127.6666666666667" CenterY="884.0" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000015314" /> </DataNode> <DataNode TextLabel="Lysine biosynthesis" GraphId="ac9a7" Type="Pathway"> <Graphics CenterX="1093.5" CenterY="527.0" Width="125.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ABAT" GraphId="aca" Type="GeneProduct" GroupRef="ba4cb"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:18</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ABAT | 4-aminobutyrate aminotransferase" /> <Graphics CenterX="665.5000203450521" CenterY="506.0" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000004038" /> </DataNode> <DataNode TextLabel="4.1.1.11" GraphId="adf" Type="GeneProduct" GroupRef="a9af5"> <Graphics CenterX="867.0" CenterY="397.6666971842448" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="1.4.3.2" GraphId="ae1" Type="GeneProduct" GroupRef="dfc9e"> <Graphics CenterX="620.6666666666666" CenterY="960.6666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="4.1.1.12" GraphId="afd" Type="GeneProduct"> <Graphics CenterX="907.0" CenterY="316.0" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="DARS" GraphId="aff" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1615</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="DARS | aspartyl-tRNA synthetase" /> <Graphics CenterX="1140.6666666666667" CenterY="1090.6666666666667" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000009949" /> </DataNode> <DataNode TextLabel="ASPA" GraphId="b10" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:443</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ASPA | aspartoacylase (aminoacylase 2 Canavan ..." /> <Graphics CenterX="749.6666666666666" CenterY="945.0" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000003629" /> </DataNode> <DataNode TextLabel="N-Carbamoyl-L-aspartate" GraphId="b174e" Type="Metabolite"> <Graphics CenterX="652.0" CenterY="710.0" Width="128.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="ChEBI" ID="CHEBI:15859" /> </DataNode> <DataNode TextLabel="D-Alanine" GraphId="b23" Type="Metabolite"> <Comment Source="GenMAPP remarks">D-Alanine</Comment> <Graphics CenterX="1112.0" CenterY="236.66666666666666" Width="59.333333333333336" Height="15.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="CAS" ID="338-69-2" /> </DataNode> <DataNode TextLabel="5.1.1.1" GraphId="b27" Type="GeneProduct"> <Graphics CenterX="1035.0" CenterY="210.66666666666666" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="2.6.1.12" GraphId="b8d" Type="GeneProduct"> <Graphics CenterX="731.6666666666666" CenterY="193.66666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="b-Alanine" GraphId="b94" Type="Metabolite"> <Comment Source="GenMAPP remarks">beta-alanine</Comment> <Graphics CenterX="717.0833333333334" CenterY="477.5833333333333" Width="58.166666666666664" Height="16.833333333333332" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="CAS" ID="6912-68-1" /> </DataNode> <DataNode TextLabel="DARS" GraphId="ba3" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1615</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="DARS | aspartyl-tRNA synthetase" /> <Graphics CenterX="921.3333333333334" CenterY="664.6666666666666" Width="41.33333333333329" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000009949" /> </DataNode> <DataNode TextLabel="AGXT" GraphId="bcc" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:189</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AGXT | alanine-glyoxylate aminotransferase (oxa..." /> <Graphics CenterX="751.6666666666666" CenterY="262.5" Width="46.666666666666664" Height="19.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000005797" /> </DataNode> <DataNode TextLabel="Glycine, serine and threonine metabolism" GraphId="bd17e" Type="Pathway"> <Graphics CenterX="1151.0" CenterY="484.0" Width="242.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="L-Asparagine acid" GraphId="be00d" Type="Metabolite" GroupRef="b758d"> <Graphics CenterX="926.5" CenterY="1176.0" Width="96.5" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="CAS" ID="70-47-3" /> </DataNode> <DataNode TextLabel="6.3.1.1" GraphId="c02" Type="GeneProduct"> <Graphics CenterX="926.1666666666666" CenterY="953.3333333333334" Width="40.33333333333326" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="1.2.1.18" GraphId="c1a" Type="GeneProduct"> <Graphics CenterX="576.6666666666666" CenterY="616.6666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Acetyl-CoA" GraphId="c39" Type="Metabolite"> <Comment Source="GenMAPP remarks">Acetyl-CoA</Comment> <Graphics CenterX="535.6666666666666" CenterY="477.6666666666667" Width="67.33333333333333" Height="15.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="CAS" ID="72-89-9" /> </DataNode> <DataNode TextLabel="5.1.1.13" GraphId="c41" Type="GeneProduct"> <Graphics CenterX="812.0" CenterY="844.6666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="L-Aspartic acid" GraphId="c4eaa" Type="Metabolite" GroupRef="ac2a6"> <Graphics CenterX="859.0" CenterY="614.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="KEGG Compound" ID="C00049" /> </DataNode> <DataNode TextLabel="GPT" GraphId="c4f" Type="GeneProduct"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2875</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GPT | glutamic-pyruvate transaminase (alanine a..." /> <Graphics CenterX="682.6666666666666" CenterY="263.33333333333337" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Ensembl" ID="ENSBTAG00000007835" /> </DataNode> <DataNode TextLabel="3.5.1.7" GraphId="c70" Type="GeneProduct"> <Graphics CenterX="755.6666666666666" CenterY="796.3333333333334" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="N-Acetyl-L-aspartate" GraphId="c83b6" Type="Metabolite"> <Graphics CenterX="724.5" CenterY="1006.0" Width="107.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Pyrimidine metabolism" GraphId="c8f0c" Type="Pathway"> <Graphics CenterX="650.5" CenterY="387.0" Width="143.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="6.3.5.6" GraphId="ca3" Type="GeneProduct"> <Graphics CenterX="1024.6666666666665" CenterY="1203.0" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="3.5.1.38" GraphId="cba" Type="GeneProduct" GroupRef="cf1aa"> <Graphics CenterX="827.6666666666666" CenterY="977.6666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="4.3.1.1" GraphId="cc2" Type="GeneProduct"> <Graphics CenterX="1128.0" CenterY="1014.3333333333334" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="2.3.1.7" GraphId="cc7" Type="GeneProduct"> <Graphics CenterX="472.3333333333333" CenterY="438.3333333333333" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="tRNA (Asn)" GraphId="cee19" Type="GeneProduct" GroupRef="b758d"> <Graphics CenterX="926.5" CenterY="1156.0" Width="96.5" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="1.4.3.15" GraphId="cfc" Type="GeneProduct" GroupRef="dd7c3"> <Graphics CenterX="591.0" CenterY="826.6666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="D-Ala metabolism" GraphId="cff02" Type="Pathway"> <Graphics CenterX="1093.5" CenterY="53.0" Width="113.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Malate" GraphId="d06" Type="Metabolite"> <Comment Source="GenMAPP remarks">(S)-Malate</Comment> <Graphics CenterX="116.83333333333333" CenterY="962.75" Width="49.66666666666666" Height="20.5" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="CAS" ID="6915-15-7" /> </DataNode> <DataNode TextLabel="3.5.1.1" GraphId="d0b" Type="GeneProduct" GroupRef="cf1aa"> <Graphics CenterX="827.6666666666666" CenterY="997.6666666666666" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Cyanoamino acid metabolism" GraphId="d1d97" Type="Pathway"> <Graphics CenterX="814.5" CenterY="36.0" Width="171.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="tRNA(Asp)" GraphId="d25c6" Type="GeneProduct" GroupRef="ac2a6"> <Graphics CenterX="859.0" CenterY="594.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Succinate" GraphId="d35fd" Type="Metabolite"> <Graphics CenterX="113.0" CenterY="1116.0" Width="62.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="KEGG Compound" ID="C00042" /> </DataNode> <DataNode TextLabel="Malonate semialdehyde" GraphId="d3aab" Type="Metabolite"> <Graphics CenterX="685.5" CenterY="585.0" Width="127.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="ChEBI" ID="CHEBI:33190" /> </DataNode> <DataNode TextLabel="6.3.2.11" GraphId="d4b" Type="GeneProduct"> <Graphics CenterX="794.0" CenterY="412.0" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="beta-Alanine metabolism" GraphId="d5802" Type="Pathway"> <Graphics CenterX="1106.0" CenterY="569.0" Width="158.0" Height="16.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Citric acid" GraphId="d60d1" Type="Metabolite"> <Graphics CenterX="534.5" CenterY="962.0" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="HMDB" ID="HMDB0000094" /> </DataNode> <DataNode TextLabel="1.4.3.16" GraphId="d6e" Type="GeneProduct" GroupRef="dfc9e"> <Graphics CenterX="620.6666666666666" CenterY="980.6667073567709" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="6.1.1.22" GraphId="d73" Type="GeneProduct"> <Graphics CenterX="892.0" CenterY="1103.3333333333333" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Urea cycel and metabolism of amino groups" GraphId="d73ae" Type="Pathway"> <Graphics CenterX="1167.0" CenterY="618.0" Width="270.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="RoundedRectangle" Color="14961e" /> <Xref Database="WikiPathways" ID="WP497" /> </DataNode> <DataNode TextLabel="L-Asparagine acid" GraphId="d7a4f" Type="Metabolite" GroupRef="f4a1b"> <Graphics CenterX="1108.5" CenterY="1176.0" Width="96.5" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="CAS" ID="70-47-3" /> </DataNode> <DataNode TextLabel="2.6.1.18" GraphId="d7d" Type="GeneProduct" GroupRef="ba4cb"> <Graphics CenterX="614.6666666666666" CenterY="506.0" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Adenylosuccinate" GraphId="d9688" Type="Metabolite"> <Graphics CenterX="1214.625" CenterY="752.75" Width="100.75" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Oxaloacetate" GraphId="da543" Type="Metabolite"> <Graphics CenterX="370.0" CenterY="962.0" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" Color="0000ff" /> <Xref Database="KEGG Compound" ID="C00036" /> </DataNode> <DataNode TextLabel="2.6.1.14" GraphId="daf" Type="GeneProduct"> <Graphics CenterX="714.3333333333334" CenterY="1102.0" Width="55.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Histidine metabolism" GraphId="dec22" Type="Pathway"> <Graphics CenterX="1082.0" CenterY="691.0" Width="140.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="Arginine and Proline metabolism" GraphId="df01d" Type="Pathway"> <Graphics CenterX="1136.5" CenterY="653.0" Width="207.0" Height="20.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" ShapeType="None" Color="14961e" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="tRNA (Asn)" GraphId="e0b6b" Type="GeneProduct" GroupRef="f4a1b"> <Graphics CenterX="1108.5" CenterY="1156.0" Width="96.5" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="6.1.1.7" GraphId="e4d" Type="GeneProduct"> <Graphics CenterX="997.6666666666666" CenterY="165.0" Width="46.666666666666664" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="GAD2" GraphId="e52" Type="GeneProduct" GroupRef="a9af5"> <Comment Source="HomologyConvert">HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2572</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GAD2 | glutamate decarboxylase 2 (pancreatic is..." /> <Graphics CenterX="867.0" 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