Integrin-mediated cell adhesion (Gallus gallus)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Integrin-mediated cell adhesion" Last-Modified="5/1/2013" Organism="Gallus gallus"> <Comment Source="WikiPathways-category">Cellular Process</Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP185&amp;oldid=21067 WP185(r21067)] with a 73% conversion rate.</Comment> <Comment Source="WikiPathways-description">Integrins are receptors that mediate attachment between a cell and the tissues surrounding it, which may be other cells or the extracellular matrix (ECM). They also play a role in cell signaling and thereby define cellular shape, mobility, and regulate the cell cycle. Source: [[wikipedia:Integrins|Wikipedia]]</Comment> <BiopaxRef>b40</BiopaxRef> <Graphics BoardWidth="1145.1666666666667" BoardHeight="706.6666666666667" /> <DataNode TextLabel="ITGA4" GraphId="a0e" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA4" /> <Graphics CenterX="720.0" CenterY="620.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="424121" /> </DataNode> <DataNode TextLabel="CAPN9" GraphId="a13" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN9; calpain 9 (nCL-4) [EC:3.4.22.17</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN9" /> <Graphics CenterX="200.0" CenterY="600.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="421544" /> </DataNode> <DataNode TextLabel="ACTN" GraphId="a16" Type="GeneProduct"> <Graphics CenterX="170.0" CenterY="156.66666666666666" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ILK" GraphId="a25" Type="GeneProduct"> <Comment Source="GenMAPP remarks">ILK; integrin-linked kinase [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ILK" /> <Graphics CenterX="86.66666666666667" CenterY="203.33333333333334" Width="40.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="374018" /> </DataNode> <DataNode TextLabel="PTK2" GraphId="a2d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PTK2; PTK2 protein tyrosine kinase 2 [EC:2.7.1.112</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PTK2" /> <Graphics CenterX="340.0" CenterY="220.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396416" /> </DataNode> <DataNode TextLabel="ITGB3" GraphId="a3c" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB3" /> <Graphics CenterX="970.0" CenterY="600.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="374209" /> </DataNode> <DataNode TextLabel="ITGAE" GraphId="a48" Type="GeneProduct"> <Graphics CenterX="873.3333333333334" CenterY="560.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="SOS1" GraphId="a4d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SOS1; son of sevenless homolog 1 (Drosophila)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SOS1" /> <Graphics CenterX="160.0" CenterY="446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="425964" /> </DataNode> <DataNode TextLabel="ZYX" GraphId="a66" Type="GeneProduct"> <Comment Source="GenMAPP remarks">ZYX; zyxin</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ZYX" /> <Graphics CenterX="173.33333333333334" CenterY="100.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="418300" /> </DataNode> <DataNode TextLabel="RAP1A" GraphId="a71" Type="GeneProduct" GroupRef="ace1c"> <Comment Source="GenMAPP remarks">RAP1A; RAP1A member of RAS oncogene family</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAP1A" /> <Graphics CenterX="800.0" CenterY="60.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="419867" /> </DataNode> <DataNode TextLabel="ITGAM" GraphId="a75" Type="GeneProduct"> <Graphics CenterX="873.3333333333334" CenterY="620.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CRK" GraphId="a80" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CRK; v-crk sarcoma virus CT10 oncogene homolog (avian</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CRK" /> <Graphics CenterX="593.3333333333334" CenterY="70.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="417553" /> </DataNode> <DataNode TextLabel="ITGA7" GraphId="a85" Type="GeneProduct"> <Graphics CenterX="796.6666666666666" CenterY="560.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ITGB7" GraphId="aaa" Type="GeneProduct"> <Graphics CenterX="1046.6666666666667" CenterY="560.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="MYO-P" GraphId="ab0" Type="GeneProduct"> <Graphics CenterX="763.3333333333334" CenterY="363.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CAPN5" GraphId="ac4" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN5; calpain</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN5" /> <Graphics CenterX="106.66666666666667" CenterY="640.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="419086" /> </DataNode> <DataNode TextLabel="ITGAD" GraphId="acd" Type="GeneProduct"> <Graphics CenterX="873.3333333333334" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="SEPP1" GraphId="ae2" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SEPP1; selenoprotein P plasma</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SEPP1" /> <Graphics CenterX="496.6666666666667" CenterY="570.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="431587" /> </DataNode> <DataNode TextLabel="ROCK1" GraphId="ae6" Type="GeneProduct" GroupRef="e1eeb"> <Comment Source="GenMAPP remarks">ROCK1; Rho-associated coiled-coil containing protein kinase</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ROCK1" /> <Graphics CenterX="626.6666666666666" CenterY="353.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373970" /> </DataNode> <DataNode TextLabel="ITGAV" GraphId="b01" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGAV" /> <Graphics CenterX="873.3333333333334" CenterY="640.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396420" /> </DataNode> <DataNode TextLabel="ITGA3" GraphId="b06" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA3" /> <Graphics CenterX="720.0" CenterY="600.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373946" /> </DataNode> <DataNode TextLabel="VCL" GraphId="b0b" Type="GeneProduct"> <Comment Source="GenMAPP remarks">VCL; vinculin</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VCL" /> <Graphics CenterX="250.0" CenterY="156.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396422" /> </DataNode> <DataNode TextLabel="RAPGEF1" GraphId="b19" Type="GeneProduct"> <Comment Source="GenMAPP remarks">GRF2; guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAPGEF1" /> <Graphics CenterX="696.6666666666666" CenterY="70.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="417173" /> </DataNode> <DataNode TextLabel="ITGA2B" GraphId="b20" Type="GeneProduct"> <Graphics CenterX="796.6666666666666" CenterY="660.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CAPN6" GraphId="b75" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN6; calpain 6 [EC:3.4.22.17]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN6" /> <Graphics CenterX="106.66666666666667" CenterY="660.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="422341" /> </DataNode> <DataNode TextLabel="RAC2" GraphId="bbf" Type="GeneProduct"> <Comment Source="GenMAPP remarks">RAC2; ras-related C3 botulinum toxin substrate 2 (rho family small GTP binding protein Rac2)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAC2" /> <Graphics CenterX="830.0" CenterY="213.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="418044" /> </DataNode> <DataNode TextLabel="PXN" GraphId="bda" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PXN; paxillin</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PXN" /> <Graphics CenterX="280.0" CenterY="180.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395832" /> </DataNode> <DataNode TextLabel="PAK6" GraphId="c2b" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PAK6; p21(CDKN1A)-activated kinase</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PAK6" /> <Graphics CenterX="293.3333333333333" CenterY="656.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="428837" /> </DataNode> <DataNode TextLabel="MAP2K1" GraphId="c2f" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAP2K1" /> <Graphics CenterX="496.6666666666667" CenterY="470.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="415549" /> </DataNode> <DataNode TextLabel="BCAR1" GraphId="c36" Type="GeneProduct"> <Comment Source="GenMAPP remarks">BCAR1; breast cancer anti-estrogen resistance 1</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="BCAR1" /> <Graphics CenterX="463.3333333333333" CenterY="106.66666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="415691" /> </DataNode> <DataNode TextLabel="ITGB4" GraphId="c57" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB4" /> <Graphics CenterX="970.0" CenterY="620.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="417374" /> </DataNode> <DataNode TextLabel="ITGB8" GraphId="ca1" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB8" /> <Graphics CenterX="1046.6666666666667" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="420605" /> </DataNode> <DataNode TextLabel="PDPK1" GraphId="cad" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.1.37]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PDPK1" /> <Graphics CenterX="710.0" CenterY="253.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="416588" /> </DataNode> <DataNode TextLabel="CAPN3" GraphId="cb5" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN3; calpain 3 (p94) [EC:3.4.22.17]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN3" /> <Graphics CenterX="106.66666666666667" CenterY="620.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="423233" /> </DataNode> <DataNode TextLabel="SRC" GraphId="cc0" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [EC:2.7.1.112]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SRC" /> <Graphics CenterX="236.66666666666666" CenterY="286.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396442" /> </DataNode> <DataNode TextLabel="DOCK1" GraphId="cd0" Type="GeneProduct"> <Comment Source="GenMAPP remarks">DOCK1; dedicator of cyto-kinesis</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="DOCK1" /> <Graphics CenterX="593.3333333333334" CenterY="93.33333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="423960" /> </DataNode> <DataNode TextLabel="VAV3" GraphId="cd2" Type="GeneProduct" GroupRef="d5b16"> <Comment Source="GenMAPP remarks">VAV3; vav 3 oncogene</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VAV3" /> <Graphics CenterX="710.0" CenterY="223.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373939" /> </DataNode> <DataNode TextLabel="BRAF" GraphId="cde" Type="GeneProduct"> <Comment Source="GenMAPP remarks">BRAF; v-raf murine sarcoma viral oncogene homolog B1 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="BRAF" /> <Graphics CenterX="396.6666666666667" CenterY="490.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396239" /> </DataNode> <DataNode TextLabel="CAV2" GraphId="cf0" Type="GeneProduct" GroupRef="feaf9"> <Comment Source="GenMAPP remarks">CAV2; caveolin 2</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAV2" /> <Graphics CenterX="116.66666666666667" CenterY="276.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="417772" /> </DataNode> <DataNode TextLabel="ITGAL" GraphId="d01" Type="GeneProduct"> <Graphics CenterX="873.3333333333334" CenterY="600.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ARAF" GraphId="d05" Type="GeneProduct"> <Comment Source="GenMAPP remarks">ARAF1; v-raf murine sarcoma 3611 viral oncogene homolog 1 [EC:2.7.1.-]</Comment> <Graphics CenterX="396.6666666666667" CenterY="510.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CAPN11" GraphId="d07" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN11; calpain 11 [EC:3.4.22.17]</Comment> <Graphics CenterX="200.0" CenterY="640.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CAPN10" GraphId="d15" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN10; calpain 10 [EC:3.4.22.17</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN10" /> <Graphics CenterX="200.0" CenterY="620.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="424945" /> </DataNode> <DataNode TextLabel="ITGAX" GraphId="d16" Type="GeneProduct"> <Graphics CenterX="873.3333333333334" CenterY="660.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ITGA1" GraphId="d1b" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA1" /> <Graphics CenterX="720.0" CenterY="560.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395951" /> </DataNode> <DataNode TextLabel="FYN" GraphId="d21" Type="GeneProduct"> <Comment Source="GenMAPP remarks">FYN; FYN oncogene related to SRC FGR YES [EC:2.7.1.112]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="FYN" /> <Graphics CenterX="160.0" CenterY="380.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396294" /> </DataNode> <DataNode TextLabel="MAPK10" GraphId="d24" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAPK10" /> <Graphics CenterX="903.3333333333334" CenterY="70.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="422592" /> </DataNode> <DataNode TextLabel="CSK" GraphId="d4e" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CSK; c-src tyrosine kinase [EC:2.7.1.112]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CSK" /> <Graphics CenterX="463.3333333333333" CenterY="136.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396396" /> </DataNode> <DataNode TextLabel="CAV3" GraphId="d4f" Type="GeneProduct" GroupRef="feaf9"> <Comment Source="GenMAPP remarks">CAV3; caveolin 3</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAV3" /> <Graphics CenterX="116.66666666666667" CenterY="296.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="378796" /> </DataNode> <DataNode TextLabel="RHO" GraphId="d5d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">RHO; rhodopsin (opsin 2 rod pigment) (retinitis pigmentosa 4 autosomal dominant)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RHO" /> <Graphics CenterX="493.3333333333333" CenterY="363.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396486" /> </DataNode> <DataNode TextLabel="HRAS" GraphId="d66" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="HRAS" /> <Graphics CenterX="273.3333333333333" CenterY="446.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396229" /> </DataNode> <DataNode TextLabel="MAPK7" GraphId="d6b" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAPK7; mitogen-activated protein kinase 7 [EC:2.7.1.-</Comment> <Graphics CenterX="596.6666666666666" CenterY="530.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="CAV1" GraphId="d79" Type="GeneProduct" GroupRef="feaf9"> <Comment Source="GenMAPP remarks">CAV1; caveolin 1 caveolae protein 22kD</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAV1" /> <Graphics CenterX="116.66666666666667" CenterY="256.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373996" /> </DataNode> <DataNode TextLabel="ITGB6" GraphId="d80" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB6" /> <Graphics CenterX="970.0" CenterY="660.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="424191" /> </DataNode> <DataNode TextLabel="RCJMB04_5i17" GraphId="d81" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAPK6; mitogen-activated protein kinase 6 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RCJMB04_5i17" /> <Graphics CenterX="596.6666666666666" CenterY="510.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="415419" /> </DataNode> <DataNode TextLabel="SHC1" GraphId="d86" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SHC1; SHC (Src homology 2 domain containing) transforming protein 1</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SHC1" /> <Graphics CenterX="200.0" CenterY="340.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395934" /> </DataNode> <DataNode TextLabel="ITGB1" GraphId="d8c" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB1" /> <Graphics CenterX="970.0" CenterY="560.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="374058" /> </DataNode> <DataNode TextLabel="CAPN2" GraphId="d8d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN2; calpain 2 (m/II) large subunit [EC:3.4.22.17]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN2" /> <Graphics CenterX="106.66666666666667" CenterY="600.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395963" /> </DataNode> <DataNode TextLabel="AKT3" GraphId="d90" Type="GeneProduct" GroupRef="c03b0"> <Comment Source="GenMAPP remarks">AKT3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B gamma) [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKT3" /> <Graphics CenterX="900.0" CenterY="306.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="421497" /> </DataNode> <DataNode TextLabel="MAP2K2" GraphId="d9b" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAP2K2" /> <Graphics CenterX="496.6666666666667" CenterY="490.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396349" /> </DataNode> <DataNode TextLabel="PIK3R2" GraphId="da5" Type="GeneProduct" GroupRef="de408"> <Comment Source="GenMAPP remarks">PIK3R2; phosphoinositide-3-kinase regulatory subunit polypeptide 2 (p85 beta)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PIK3R2" /> <Graphics CenterX="470.0" CenterY="266.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="771142" /> </DataNode> <DataNode TextLabel="ITGA9" GraphId="dab" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA9" /> <Graphics CenterX="796.6666666666666" CenterY="600.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="420757" /> </DataNode> <DataNode TextLabel="TNS1" GraphId="dc1" Type="GeneProduct"> <Comment Source="GenMAPP remarks">TNS; tensi</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="TNS1" /> <Graphics CenterX="340.0" CenterY="126.66666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396439" /> </DataNode> <DataNode TextLabel="CAPN7" GraphId="dc7" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN7; calpain 7 [EC:3.4.22.17</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN7" /> <Graphics CenterX="200.0" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="420683" /> </DataNode> <DataNode TextLabel="ITGA5" GraphId="dc8" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA5" /> <Graphics CenterX="720.0" CenterY="640.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="378932" /> </DataNode> <DataNode TextLabel="ITGA10" GraphId="dcb" Type="GeneProduct"> <Graphics CenterX="796.6666666666666" CenterY="620.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="RAF1" GraphId="dd7" Type="GeneProduct"> <Comment Source="GenMAPP remarks">RAF1; v-raf-1 murine leukemia viral oncogene homolog 1 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAF1" /> <Graphics CenterX="396.6666666666667" CenterY="470.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396245" /> </DataNode> <DataNode TextLabel="VAV2" GraphId="de7" Type="GeneProduct" GroupRef="d5b16"> <Comment Source="GenMAPP remarks">VAV2; vav 2 oncogene</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="VAV2" /> <Graphics CenterX="710.0" CenterY="203.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373938" /> </DataNode> <DataNode TextLabel="CDC42" GraphId="e0a" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CDC42; cell division cycle 42 (GTP binding protein 25kD)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CDC42" /> <Graphics CenterX="710.0" CenterY="170.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395917" /> </DataNode> <DataNode TextLabel="RCJMB04_36h7" GraphId="e0d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RCJMB04_36h7" /> <Graphics CenterX="496.6666666666667" CenterY="530.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="415557" /> </DataNode> <DataNode TextLabel="CAPNS1" GraphId="e13" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPNS1; calpain small subunit 1 [EC:3.4.22.17]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPNS1" /> <Graphics CenterX="206.66666666666666" CenterY="223.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="770982" /> </DataNode> <DataNode TextLabel="ITGB2" GraphId="e20" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB2" /> <Graphics CenterX="970.0" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396181" /> </DataNode> <DataNode TextLabel="PAK2" GraphId="e2e" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PAK2; p21 (CDKN1A)-activated kinase 2 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PAK2" /> <Graphics CenterX="293.3333333333333" CenterY="596.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="424860" /> </DataNode> <DataNode TextLabel="RCJMB04_8f10" GraphId="e47" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RCJMB04_8f10" /> <Graphics CenterX="496.6666666666667" CenterY="510.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="416496" /> </DataNode> <DataNode TextLabel="MAPK1" GraphId="e4d" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAPK1; mitogen-activated protein kinase 1 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAPK1" /> <Graphics CenterX="596.6666666666666" CenterY="470.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373953" /> </DataNode> <DataNode TextLabel="SORBS1" GraphId="e65" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SH3D5; SH3-domain protein 5 (ponsin</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SORBS1" /> <Graphics CenterX="306.6666666666667" CenterY="80.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="423749" /> </DataNode> <DataNode TextLabel="PI5K" GraphId="e6a" Type="GeneProduct"> <Graphics CenterX="550.0" CenterY="326.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="RAP1B" GraphId="e6b" Type="GeneProduct" GroupRef="ace1c"> <Comment Source="GenMAPP remarks">RAP1B; RAP1B member of RAS oncogene family</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAP1B" /> <Graphics CenterX="800.0" CenterY="80.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="417840" /> </DataNode> <DataNode TextLabel="SRC" GraphId="e72" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [EC:2.7.1.112]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SRC" /> <Graphics CenterX="523.3333333333334" CenterY="120.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396442" /> </DataNode> <DataNode TextLabel="MAP2K6" GraphId="ea6" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.1.-</Comment> <Graphics CenterX="496.6666666666667" CenterY="550.0" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="PAK3" GraphId="eac" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PAK3; p21 (CDKN1A)-activated kinase 3 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PAK3" /> <Graphics CenterX="293.3333333333333" CenterY="616.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="422342" /> </DataNode> <DataNode TextLabel="ITGA2" GraphId="ece" Type="GeneProduct"> <Graphics CenterX="720.0" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="AKT2" GraphId="ecf" Type="GeneProduct" GroupRef="c03b0"> <Comment Source="GenMAPP remarks">AKT2; v-akt murine thymoma viral oncogene homolog 2 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKT2" /> <Graphics CenterX="900.0" CenterY="286.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="373973" /> </DataNode> <DataNode TextLabel="CAPN1" GraphId="ed3" Type="GeneProduct"> <Comment Source="GenMAPP remarks">CAPN1; calpain 1 (mu/I) large subunit [EC:3.4.22.17]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="CAPN1" /> <Graphics CenterX="106.66666666666667" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396240" /> </DataNode> <DataNode TextLabel="RAC1" GraphId="ed7" Type="GeneProduct"> <Comment Source="GenMAPP remarks">RAC1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAC1" /> <Graphics CenterX="830.0" CenterY="193.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395871" /> </DataNode> <DataNode TextLabel="ROCK2" GraphId="ede" Type="GeneProduct" GroupRef="e1eeb"> <Comment Source="GenMAPP remarks">ROCK2; Rho-associated coiled-coil containing protein kinase</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ROCK2" /> <Graphics CenterX="626.6666666666666" CenterY="373.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="374182" /> </DataNode> <DataNode TextLabel="GIT2" GraphId="edf" Type="GeneProduct"> <Comment Source="GenMAPP remarks">GIT2; G protein-coupled receptor kinase-interactor 2</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GIT2" /> <Graphics CenterX="760.0" CenterY="136.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="374035" /> </DataNode> <DataNode TextLabel="MYO" GraphId="ee2" Type="GeneProduct"> <Graphics CenterX="900.0" CenterY="363.3333333333333" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="VASP" GraphId="ef9" Type="GeneProduct"> <Comment Source="GenMAPP remarks">VASP; vasodilator-stimulated phosphoprotein</Comment> <Graphics CenterX="233.33333333333334" CenterY="130.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="p110" GraphId="f05" Type="GeneProduct" GroupRef="de408"> <Graphics CenterX="470.0" CenterY="286.6666666666667" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="ITGA6" GraphId="f24" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA6" /> <Graphics CenterX="720.0" CenterY="660.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396226" /> </DataNode> <DataNode TextLabel="PAK1" GraphId="f3c" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PAK1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog yeast) [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PAK1" /> <Graphics CenterX="293.3333333333333" CenterY="576.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="419083" /> </DataNode> <DataNode TextLabel="AKT1" GraphId="f4a" Type="GeneProduct" GroupRef="c03b0"> <Comment Source="GenMAPP remarks">AKT1; v-akt murine thymoma viral oncogene homolog 1 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="AKT1" /> <Graphics CenterX="900.0" CenterY="266.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395928" /> </DataNode> <DataNode TextLabel="GRB2" GraphId="f57" Type="GeneProduct"> <Comment Source="GenMAPP remarks">GRB2; growth factor receptor-bound protein 2</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="GRB2" /> <Graphics CenterX="240.0" CenterY="380.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="386572" /> </DataNode> <DataNode TextLabel="ITGB5" GraphId="f5c" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGB5" /> <Graphics CenterX="970.0" CenterY="640.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395142" /> </DataNode> <DataNode TextLabel="ITGA8" GraphId="f6e" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA8" /> <Graphics CenterX="796.6666666666666" CenterY="580.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396225" /> </DataNode> <DataNode TextLabel="ITGA11" GraphId="f82" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ITGA11" /> <Graphics CenterX="796.6666666666666" CenterY="640.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="415560" /> </DataNode> <DataNode TextLabel="ARHGEF7" GraphId="f96" Type="GeneProduct"> <Comment Source="GenMAPP remarks">ARHGEF7; Rho guanine nucleotide exchange factor (GEF) 7</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="ARHGEF7" /> <Graphics CenterX="886.6666666666666" CenterY="136.66666666666666" Width="66.66666666666667" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="418761" /> </DataNode> <DataNode TextLabel="MYLK2" GraphId="fa2" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MYLK2; myosin light chain kinase 2 skeletal muscle [EC:2.7.1.117</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="MYLK2" /> <Graphics CenterX="790.0" CenterY="430.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396356" /> </DataNode> <DataNode TextLabel="PAK4" GraphId="fb9" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PAK4; p21(CDKN1A)-activated kinase 4 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PAK4" /> <Graphics CenterX="293.3333333333333" CenterY="636.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="770462" /> </DataNode> <DataNode TextLabel="MAPK4" GraphId="fc1" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAPK4; mitogen-activated protein kinase 4 [EC:2.7.1.-]</Comment> <Graphics CenterX="596.6666666666666" CenterY="490.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="" ID="" /> </DataNode> <DataNode TextLabel="MAPK12" GraphId="fca" Type="GeneProduct"> <Comment Source="GenMAPP remarks">MAPK12; mitogen-activated protein kinase 12 [EC:2.7.1.-]</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="MAPK12" /> <Graphics CenterX="596.6666666666666" CenterY="550.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="769763" /> </DataNode> <DataNode TextLabel="RAC3" GraphId="fcc" Type="GeneProduct"> <Comment Source="GenMAPP remarks">RAC3; ras-related C3 botulinum toxin substrate 3 (rho family small GTP binding protein Rac3)</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RAC3" /> <Graphics CenterX="830.0" CenterY="233.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395870" /> </DataNode> <DataNode TextLabel="TLN1" GraphId="fe5" Type="GeneProduct"> <Comment Source="GenMAPP remarks">TLN1; talin 1</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="TLN1" /> <Graphics CenterX="210.0" CenterY="180.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="395194" /> </DataNode> <DataNode TextLabel="SHC3" GraphId="ff0" Type="GeneProduct"> <Comment Source="GenMAPP remarks">SHC3; neuronal Sh</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="SHC3" /> <Graphics CenterX="200.0" CenterY="360.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="431265" /> </DataNode> <DataNode TextLabel="PTK2" GraphId="ff6" Type="GeneProduct"> <Comment Source="GenMAPP remarks">PTK2; PTK2 protein tyrosine kinase 2 [EC:2.7.1.112</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PTK2" /> <Graphics CenterX="340.0" CenterY="286.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle" /> <Xref Database="Entrez Gene" ID="396416" /> </DataNode> <Interaction GraphId="id1bb599f0"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="550.0" Y="316.6666666666667" GraphRef="e6a" RelX="0.0" RelY="-1.0" /> <Point X="566.6666666666666" Y="264.90356" GraphRef="f90c8" RelX="0.0" RelY="1.0" ArrowHead="Arrow" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id1beed265"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="203.33333333333334" Y="100.0" GraphRef="a66" RelX="1.0" RelY="0.0" /> <Point X="218.33333333333337" Y="120.0" GraphRef="ef9" RelX="-0.5" RelY="-1.0" /> </Graphics> <Xref Database="" ID="" /> </Interaction> <Interaction GraphId="id1e9ed283"> <Graphics ZOrder="12288" LineThickness="1.0"> <Point X="790.0" 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<bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#"> <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">integrin mediated signaling pathway</bp:TERM> <bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000286</bp:ID> <bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology> </bp:openControlledVocabulary> <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="b40"> <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">16125000</bp:ID> <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Assembly and signaling of adhesion complexes.</bp:TITLE> <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Curr Top Dev Biol</bp:SOURCE> <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2005</bp:YEAR> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sepulveda JL</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Gkretsi V</bp:AUTHORS> <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Wu C</bp:AUTHORS> </bp:PublicationXref> </Biopax> </Pathway>

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