Proteasome degradation (Pan troglodytes)

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<?xml version="1.0" encoding="UTF-8"?> <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Proteasome degradation" Organism="Pan troglodytes"> <Comment Source="WikiPathways-description">Degradation by proteasomes is part of the mechanism by which cells regulate the concentration of proteins and degrade misfolded proteins. Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Proteins are tagged for degradation by proteasomes by the addition of ubiquitin, by ubiquitin ligases. Description adapted from [Wikipedia](https://en.wikipedia.org/wiki/Proteasome).</Comment> <Comment Source="WikiPathways-category">Physiological Process</Comment> <Comment Source="HomologyConvert">This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP183&amp;amp;oldid=29614 WP183(r29614)] with a 74% conversion rate.</Comment> <Graphics BoardWidth="878.6666666666667" BoardHeight="893.3333333333334"/> <DataNode TextLabel="H2AFJ" GraphId="dec" Type="GeneProduct" GroupRef="f26af"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="H2AFJ"/> <Graphics CenterX="93.33333333333333" CenterY="133.33333333333334" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="465306"/> </DataNode> <DataNode TextLabel="LOC461400" GraphId="cb2" Type="GeneProduct" GroupRef="f26af"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="LOC461400"/> <Graphics CenterX="93.33333333333333" CenterY="153.33333333333334" Width="80.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="461400"/> </DataNode> <DataNode TextLabel="UBA1" GraphId="c5c" Type="GeneProduct" GroupRef="aa4b9"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBA1"/> <Graphics CenterX="430.3333333333333" CenterY="76.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="749307"/> </DataNode> <DataNode TextLabel="UBA7" GraphId="e53" Type="GeneProduct" GroupRef="aa4b9"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBA7"/> <Graphics CenterX="430.3333333333333" CenterY="96.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="744322"/> </DataNode> <DataNode TextLabel="UBE2B" GraphId="bfa" Type="GeneProduct" GroupRef="e6e44"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBE2B"/> <Graphics CenterX="428.3333333333333" CenterY="148.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="462065"/> </DataNode> <DataNode TextLabel="UBE2D1" GraphId="efa" Type="GeneProduct" GroupRef="e6e44"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBE2D1"/> <Graphics CenterX="428.3333333333333" CenterY="168.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="745141"/> </DataNode> <DataNode TextLabel="UBE2D2" GraphId="ddc" Type="GeneProduct" GroupRef="e6e44"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBE2D2"/> <Graphics CenterX="428.3333333333333" CenterY="188.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="462108"/> </DataNode> <DataNode TextLabel="UBE2D3P" GraphId="c25" Type="GeneProduct" GroupRef="e6e44"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBE2D3P"/> <Graphics CenterX="428.3333333333333" CenterY="208.66666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="745118"/> </DataNode> <DataNode TextLabel="PSMC1" GraphId="ed3" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC1"/> <Graphics CenterX="216.33333333333334" CenterY="423.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="453097"/> </DataNode> <DataNode TextLabel="NEDD4" GraphId="f17" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="NEDD4"/> <Graphics CenterX="542.3333333333334" CenterY="268.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="467689"/> </DataNode> <DataNode TextLabel="PSMC6" GraphId="f31" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC6"/> <Graphics CenterX="216.33333333333334" CenterY="523.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="452909"/> </DataNode> <DataNode TextLabel="PSMD1" GraphId="fae" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD1"/> <Graphics CenterX="216.33333333333334" CenterY="543.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="470674"/> </DataNode> <DataNode TextLabel="PSMD2" GraphId="fde" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD2"/> <Graphics CenterX="216.33333333333334" CenterY="563.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="460887"/> </DataNode> <DataNode TextLabel="PSMD3" GraphId="dc6" Type="GeneProduct" GroupRef="cce91"> <Graphics CenterX="216.33333333333334" CenterY="583.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PSMD4" GraphId="f37" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD4"/> <Graphics CenterX="336.3333333333333" CenterY="423.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="100192399"/> </DataNode> <DataNode TextLabel="PSMC5" GraphId="ffd" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC5"/> <Graphics CenterX="275.0" CenterY="653.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="454777"/> </DataNode> <DataNode TextLabel="PSMC2" GraphId="fc6" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC2"/> <Graphics CenterX="216.33333333333334" CenterY="443.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="463632"/> </DataNode> <DataNode TextLabel="PSMC3" GraphId="c87" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC3"/> <Graphics CenterX="216.33333333333334" CenterY="463.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="451172"/> </DataNode> <DataNode TextLabel="PSMC4" GraphId="f34" Type="GeneProduct" GroupRef="cce91"> <Comment Source="GenMAPP remarks">PRS6 HUMAN</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC4"/> <Graphics CenterX="216.33333333333334" CenterY="483.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="737578"/> </DataNode> <DataNode TextLabel="PSMA1" GraphId="e24" Type="GeneProduct" GroupRef="dcf3e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMA1"/> <Graphics CenterX="513.3333333333334" CenterY="446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="451040"/> </DataNode> <DataNode TextLabel="PSMA2" GraphId="a13" Type="GeneProduct" GroupRef="dcf3e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMA2"/> <Graphics CenterX="513.3333333333334" CenterY="466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="472653"/> </DataNode> <DataNode TextLabel="PSMB1" GraphId="b21" Type="GeneProduct" GroupRef="fd7c1"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB1"/> <Graphics CenterX="630.0" CenterY="446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="473258"/> </DataNode> <DataNode TextLabel="PSMA3" GraphId="d29" Type="GeneProduct" GroupRef="dcf3e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMA3"/> <Graphics CenterX="513.3333333333334" CenterY="486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="467469"/> </DataNode> <DataNode TextLabel="PSMA4" GraphId="f94" Type="GeneProduct" GroupRef="dcf3e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMA4"/> <Graphics CenterX="513.3333333333334" CenterY="506.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="453569"/> </DataNode> <DataNode TextLabel="PSMB3" GraphId="fd6" Type="GeneProduct" GroupRef="fd7c1"> <Graphics CenterX="630.0" CenterY="486.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PSMB6" GraphId="e85" Type="GeneProduct" GroupRef="fd7c1"> <Comment Source="GenMAPP remarks">U13393</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB6"/> <Graphics CenterX="630.0" CenterY="546.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="454453"/> </DataNode> <DataNode TextLabel="PSMB7" GraphId="fa9" Type="GeneProduct" GroupRef="fd7c1"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB7"/> <Graphics CenterX="630.0" CenterY="566.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="464723"/> </DataNode> <DataNode TextLabel="PSMB5" GraphId="eb8" Type="GeneProduct" GroupRef="fd7c1"> <Graphics CenterX="630.0" CenterY="526.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PSMB4" GraphId="c1d" Type="GeneProduct" GroupRef="fd7c1"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB4"/> <Graphics CenterX="630.0" CenterY="506.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="457293"/> </DataNode> <DataNode TextLabel="PSME1" GraphId="ae8" Type="GeneProduct" GroupRef="a791b"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSME1"/> <Graphics CenterX="796.6666666666666" CenterY="247.33333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="452809"/> </DataNode> <DataNode TextLabel="PSME2" GraphId="f9a" Type="GeneProduct" GroupRef="a791b"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSME2"/> <Graphics CenterX="796.6666666666666" CenterY="267.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="744802"/> </DataNode> <DataNode TextLabel="IFNG" GraphId="d19" Type="GeneProduct"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="IFNG"/> <Graphics CenterX="798.3333333333334" CenterY="356.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="449517"/> </DataNode> <DataNode TextLabel="PSMB9" GraphId="cf9" Type="GeneProduct" GroupRef="ae142"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB9"/> <Graphics CenterX="804.3333333333334" CenterY="532.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="746436"/> </DataNode> <DataNode TextLabel="PSMB10" GraphId="a05" Type="GeneProduct" GroupRef="ae142"> <Graphics CenterX="804.3333333333334" CenterY="552.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PSMB8" GraphId="c0c" Type="GeneProduct" GroupRef="ae142"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB8"/> <Graphics CenterX="804.3333333333334" CenterY="512.0" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="746418"/> </DataNode> <DataNode TextLabel="PSME3" GraphId="eb9" Type="GeneProduct" GroupRef="a791b"> <Graphics CenterX="796.6666666666666" CenterY="287.3333333333333" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PSMD7" GraphId="c12" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD7"/> <Graphics CenterX="336.3333333333333" CenterY="483.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="454240"/> </DataNode> <DataNode TextLabel="PSMD6" GraphId="ded" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD6"/> <Graphics CenterX="336.3333333333333" CenterY="463.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="465457"/> </DataNode> <DataNode TextLabel="PSMD8" GraphId="ff7" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD8"/> <Graphics CenterX="336.3333333333333" CenterY="503.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="468490"/> </DataNode> <DataNode TextLabel="PSMD9" GraphId="bbe" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD9"/> <Graphics CenterX="336.3333333333333" CenterY="523.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="465187"/> </DataNode> <DataNode TextLabel="PSMD10" GraphId="d96" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD10"/> <Graphics CenterX="336.3333333333333" CenterY="543.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="465803"/> </DataNode> <DataNode TextLabel="PSMD11" GraphId="c26" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD11"/> <Graphics CenterX="336.3333333333333" CenterY="563.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="454574"/> </DataNode> <DataNode TextLabel="PSMD12" GraphId="ba6" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD12"/> <Graphics CenterX="336.3333333333333" CenterY="583.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="454836"/> </DataNode> <DataNode TextLabel="PSMD13" GraphId="dda" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD13"/> <Graphics CenterX="336.3333333333333" CenterY="603.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="450913"/> </DataNode> <DataNode TextLabel="PSMC5" GraphId="bd0" Type="GeneProduct" GroupRef="cce91"> <Comment Source="GenMAPP remarks">PRS6 HUMAN</Comment> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMC5"/> <Graphics CenterX="216.33333333333334" CenterY="503.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="454777"/> </DataNode> <DataNode TextLabel="PSMA6" GraphId="e92" Type="GeneProduct" GroupRef="dcf3e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMA6"/> <Graphics CenterX="513.3333333333334" CenterY="546.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="452861"/> </DataNode> <DataNode TextLabel="PSMA7" GraphId="e1c" Type="GeneProduct" GroupRef="dcf3e"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMA7"/> <Graphics CenterX="513.3333333333334" CenterY="566.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="458383"/> </DataNode> <DataNode TextLabel="PSMA5" GraphId="b71" Type="GeneProduct" GroupRef="dcf3e"> <Graphics CenterX="513.3333333333334" CenterY="526.6666666666666" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="PSMB2" GraphId="cd9" Type="GeneProduct" GroupRef="fd7c1"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMB2"/> <Graphics CenterX="630.0" CenterY="466.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="469277"/> </DataNode> <DataNode TextLabel="PATR-A" GraphId="d95" Type="GeneProduct" GroupRef="bb4df"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PATR-A"/> <Graphics CenterX="360.0" CenterY="793.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="450151"/> </DataNode> <DataNode TextLabel="PATR-B" GraphId="fd4" Type="GeneProduct" GroupRef="bb4df"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PATR-B"/> <Graphics CenterX="360.0" CenterY="813.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="450202"/> </DataNode> <DataNode TextLabel="PATR-C" GraphId="f5f" Type="GeneProduct" GroupRef="bb4df"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PATR-C"/> <Graphics CenterX="360.0" CenterY="833.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="471962"/> </DataNode> <DataNode TextLabel="PATR-E" GraphId="b82" Type="GeneProduct" GroupRef="bb4df"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PATR-E"/> <Graphics CenterX="360.0" CenterY="853.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="462540"/> </DataNode> <DataNode TextLabel="HLA-F" GraphId="dbc" Type="GeneProduct" GroupRef="bb4df"> <Graphics CenterX="470.0" CenterY="793.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="HLA-G" GraphId="a25" Type="GeneProduct" GroupRef="bb4df"> <Graphics CenterX="470.0" CenterY="813.3333333333334" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="" ID=""/> </DataNode> <DataNode TextLabel="RPN2" GraphId="de2" Type="GeneProduct" GroupRef="d69b8"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RPN2"/> <Graphics CenterX="80.0" CenterY="446.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="458228"/> </DataNode> <DataNode TextLabel="RPN1" GraphId="c76" Type="GeneProduct" GroupRef="d69b8"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="RPN1"/> <Graphics CenterX="80.0" CenterY="426.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="460673"/> </DataNode> <DataNode TextLabel="UBC" GraphId="a09" Type="GeneProduct" GroupRef="ecb14"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="UBC"/> <Graphics CenterX="288.6666666666667" CenterY="43.333333333333336" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="467151"/> </DataNode> <DataNode TextLabel="PSMD5" GraphId="ee5" Type="GeneProduct" GroupRef="cce91"> <Attribute Key="org.pathvisio.model.BackpageHead" Value="PSMD5"/> <Graphics CenterX="336.3333333333333" CenterY="443.6666666666667" Width="60.0" Height="20.0" ZOrder="32768" FontSize="10" Valign="Middle"/> <Xref Database="Entrez Gene" ID="464699"/> </DataNode> <DataNode TextLabel="HLA-H" GraphId="cf0" Type="GeneProduct" 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