Thread:Disease ontology (1)
From WikiPathways
(Difference between revisions)
(New page: I noticed that a lot of pathways that are not really disease pathways are annotated with the disease ontology. This case for example, has "disease of response to stimulus", but it's really...) |
Current revision (10:41, 6 October 2011) (view source) |
||
| Line 1: | Line 1: | ||
I noticed that a lot of pathways that are not really disease pathways are annotated with the disease ontology. This case for example, has "disease of response to stimulus", but it's really just a cell signaling pathway. | I noticed that a lot of pathways that are not really disease pathways are annotated with the disease ontology. This case for example, has "disease of response to stimulus", but it's really just a cell signaling pathway. | ||
| - | By that argumentation, any signaling pathway is automatically also a "disease of response to stimulus". But I think that is very redundant. I feel there must be something specific about the diseased state in the pathway in order for it to qualify for a term from the disease ontology. | + | By that argumentation, any signaling pathway is automatically also a "disease of response to stimulus". But I think that is very redundant. I feel there must be something specific about the diseased state in the pathway in order for it to qualify for a term from the disease ontology. And a lot of annotations from the disease ontology annotations should be replaced by pathway ontology annotations. |
Do we have a guideline on this? | Do we have a guideline on this? | ||
Current revision
I noticed that a lot of pathways that are not really disease pathways are annotated with the disease ontology. This case for example, has "disease of response to stimulus", but it's really just a cell signaling pathway.
By that argumentation, any signaling pathway is automatically also a "disease of response to stimulus". But I think that is very redundant. I feel there must be something specific about the diseased state in the pathway in order for it to qualify for a term from the disease ontology. And a lot of annotations from the disease ontology annotations should be replaced by pathway ontology annotations.
Do we have a guideline on this?
