Leukocyte-intrinsic Hippo pathway functions (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none IntracellularVesicleLeukocyteIntegrin trafficking and distributionRAB13RAP1RAPLSKAPLFA-1Myosin IIaLymphocyte motility, migration,thymic egressintegrinsLymphocyte adhesionand extravasationRHOALFA-1PPYAPPYWHAQPPTAZYAP1TAZTEAD1TEAD2TEAD3TEAD4PLATS1PLATS2PMOB1PMST1PMST2PSAV1PMOB1PNDR1PNDR2MST1MST2PFOXO6PFOXO4PFOXO1PFOXO3AcFOXP3FOXP3MST1MST2RAPRAPLRac1SKAPADAPLFA-1RAPRAPLRac1Kindlin-3Kindlin-3LFA-1MST1MST2RAB13Blimp1T.reg PhenotypeRAP1RAPLRHOACCR7Lymphocyte polarizationLFA-1Enhanced BCR humoral responsein B lymphocytesCD19BLIMP1Terminal differentiation/clonalexpansion of CD8+ T cellsMaturation/survival ofT cells in SLORHOAFOXO6FOXO4FOXO1FOXO3Homeostatic maintenanceNORE1BFOXO6FOXO4FOXO1FOXO3miR-21LATS1Cytoarchitecturalintegrity/specificityLPLLFA-1T.h17/T.reg differentiationof CD4+ T cellsFOXO1FOXO3p38MAPKFOXP3Antigen cross presentationby APCsKindlin-3LFA-1LFA-1LFA-1MST1MST2PLPLLFA-1LFA-1Name: Overview of leukocyte-intrinsic Hippo pathway functionsOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:Curated.pngReview changes for Approved
Image:MissingXref.pngAnnotate nodes

Ontology Terms

Disease : cancer
Cell Type : leukocyte T cell
 

Bibliography

  1. Taha Z, Janse van Rensburg HJ, Yang X; ''The Hippo Pathway: Immunity and Cancer.''; Cancers (Basel), 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
120673
Approved
view01:29, 23 December 2021EweitzModified title
104788view23:55, 14 June 2019AriuttaOntology Term : 'immune response pathway' added !
104787view23:53, 14 June 2019AriuttaOntology Term : 'cancer' added !
104786view23:47, 14 June 2019AriuttaOntology Term : 'T cell' added !
104785view23:45, 14 June 2019AriuttaAdd upregulation interactions
104784view23:03, 14 June 2019AriuttaModified description
104783view22:48, 14 June 2019AriuttaAdd a couple more identifiers.
104780view22:46, 14 June 2019AriuttaAdd edge and more identifiers. Improve layout.
104334view14:05, 17 May 2019FehrhartOntology Term : 'leukocyte' added !
103581view16:16, 18 March 2019Elisson nlGene fixed
103433view09:39, 1 March 2019Marvin M2Ontology Term : 'Hippo signaling pathway' added !
103412view17:03, 27 February 2019AriuttaNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ADAPGeneProduct2533 (Entrez Gene)
BLIMP1GeneProduct639 (Entrez Gene)
Blimp1GeneProduct639 (Entrez Gene)
CCR7GeneProduct1236 (Entrez Gene) CCR7)
CD19GeneProduct930 (Entrez Gene)
FOXO1GeneProduct2308 (Entrez Gene) FOXO
FOXO3GeneProduct2309 (Entrez Gene) FOXO
FOXO4GeneProduct4303 (Entrez Gene) FOXO
FOXO6GeneProduct100132074 (Entrez Gene) FOXO
FOXP3GeneProduct50943 (Entrez Gene) FOXO
Kindlin-3GeneProduct
Kindlin-3GeneProduct83706 (Entrez Gene)
LATS1GeneProduct9113 (Entrez Gene) LATS1)
LATS2GeneProduct26524 (Entrez Gene)
LFA-1GeneProduct3683 (Entrez Gene)
LPLGeneProduct4023 (Entrez Gene) LPL
Lymphocyte motility, migration, thymic egressPathway
MOB1GeneProduct55233 (Entrez Gene)
MST1GeneProduct4485 (Entrez Gene) MST1/2
MST2GeneProduct
MST2GeneProduct6788 (Entrez Gene)
NDR1GeneProduct10397 (Entrez Gene)
NDR2GeneProduct23012 (Entrez Gene)
NORE1BGeneProduct83593 (Entrez Gene)
RAB13GeneProduct5872 (Entrez Gene) Rab13
RAP1GeneProduct5906 (Entrez Gene)
RAPGeneProduct83593 (Entrez Gene)
RAPLGeneProduct83593 (Entrez Gene)
RHOAGeneProduct387 (Entrez Gene) RhoA
Rac1GeneProduct5879 (Entrez Gene)
SAV1GeneProduct60485 (Entrez Gene)
SKAPGeneProduct
SKAPGeneProduct90417 (Entrez Gene)
TAZGeneProduct6901 (Entrez Gene) YAP/TAZ
TEAD1GeneProduct7003 (Entrez Gene)
TEAD2GeneProduct8463 (Entrez Gene)
TEAD3GeneProduct7005 (Entrez Gene)
TEAD4GeneProduct7004 (Entrez Gene)
YAPGeneProduct10413 (Entrez Gene)
YAP1GeneProduct10413 (Entrez Gene)
YWHAQGeneProduct10971 (Entrez Gene) 14-3-3
integrinsGeneProductPF08441 (Pfam)
miR-21GeneProduct406991 (Entrez Gene)
p38MAPKGeneProduct1432 (Entrez Gene)

Annotated Interactions

No annotated interactions

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