Electron transport chain (Mus musculus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none NADH-UbiquinoneOxidoreductaseComplex IIC subunitUbiquinol-Cytochrome CReductaseMatrixCytochrome COxidaseIntermembraneSpaceComplex IVComplex IIIAssemblybinds ATP Synthase betaAdenine NucleotideTranslocatorSuccinate-UbiquinoneOxidoreductaseComplex IUncoupling ProteinComplex VATP SynthaseF0 ComplexAtp5kAtp5j2Atp5g2mt-Atp8Atp5lATP5G1Atp5sAtpif1mt-Atp6Atp5g3Atp5hAtp5f1F1 ComplexAtp5a1Atp5bAtp5dAtp5eAtp5c1StalkAtp5oAtp5jO2H+ATPSuccinatee-FADH2TCA CycleH+H+FADH+H+NAD+H2OH+H+e-e-Cytochrome CNADHUbiquinoneNdufb6Ndufc1Ndufa8Ndufa3Ndufv2Ndufa6Ndufb9Ndufs6Ndufa2mt-Nd4lNdufs5Ndufs7Ndufs4NDUFB1Ndufa9Ndufb3Ndufb4mt-Nd6mt-Nd2Ndufab1mt-Nd5Ndufa12Ndufb7Ndufa1Ndufb5Ndufs3mt-Nd1Ndufv1Ndufs1Ndufa7mt-Nd4Ndufc2Ndufb2Ndufs2Ndufb10Ndufa4Ndufa5Ndufv3Ndufa10mt-Nd3Ndufs8Gm20538Cox6b1Cox6cmt-Co2Cox5amt-Co1Cox7a2lCox6a1Cox7a1Cox4i1COX7A3Cox7a2Cox7bCox5bmt-Co3Cox8aCox6a2COX7CUqcr10Uqcr11Uqcrfs1Uqcrc2UqcrhUqcrqUqcrbUqcrc1mt-CytbSdhbSdhaSdhdSdhcSlc25a14Slc25a27Ucp3Ucp2Ucp1Slc25a5SLC25A6Slc25a4Cox15COX11Sco1Surf1Cox17Name: Electron Transport ChainLicense: CC BY 2.0Last Modified: 10/16/2013Organism: Mus musculus


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP111 (r95118) with a 94.0% conversion rate.

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Quality Tags

Image:NeedsRef.pngAdd references
Image:Curated.pngApproved version
Image:MissingXref.pngAnnotate nodes
Homology Converted

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117879
Approved
view10:21, 23 May 2021EweitzModified title
115463view08:21, 21 February 2021EgonwOne more pathway clickable
107966view09:31, 18 November 2019Fehrhartconnected unconnected line
107945view19:39, 12 November 2019PapaxModified title
106875view13:35, 17 September 2019MaintBotHMDB identifier normalization
95791view14:40, 19 January 2018MkutmonHomology conversion update
89980view18:47, 6 October 2016Mkutmonfix unconnected lines
79459view12:57, 22 March 2015EgonwFixed the data source which I forgot to update.
79217view13:32, 15 March 2015EgonwReplaced the HMDB H2 identifier with H+ from ChEBI.
74377view21:31, 15 April 2014Khanspersadjusted layout
74376view21:29, 15 April 2014Khanspersadded pathway node
71739view20:18, 17 October 2013MaintBotAutomated update of data sources
71324view17:17, 17 October 2013MaintBotAutomated update of data sources
69136view18:16, 8 July 2013MaintBotUpdated to 2013 gpml schema
67191view10:18, 26 June 2013Christine ChichesterOntology Term : 'electron transport chain pathway' added !
62836view04:55, 3 May 2013MaintBotUpdated UniProt data source
41324view00:24, 2 March 2011MaintBotRemoved redundant pathway information and comments
35239view19:45, 11 February 2010AlexanderPicoModified description
34398view22:57, 9 December 2009MaintBotAutomatic update of empty xrefs
32868view21:13, 16 September 2009MaintBotAdded more xrefs
32867view18:16, 16 September 2009MaintBotadding xrefs
32389view16:58, 15 August 2009MaintBotFixed text labels
32033view13:26, 14 August 2009MaintBotFixed group labels
31424view20:59, 13 August 2009MaintBotFixed text labels
30843view00:05, 30 July 2009MaintBotConverted from Homo sapiens
21301view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:Electron Transport Chain]] moved to [[Pathway:WP295]]: Moved to stable identifier
8010view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Electron Transport Chain]] moved to [[Pathway:Mus musculus:Electron Transport Chain]]: Renaming species
7628view16:05, 18 December 2007MaintBotfixed category names
7341view12:42, 4 November 2007MaintBotAdded categories to GPML
19422view22:18, 22 May 2007M.Braymergpml file for [[Mouse:Electron_Transport_Chain]]
6435view22:18, 22 May 2007Kdahlquistgpml file for [[Mouse:Electron_Transport_Chain]]

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
ATP5G1GeneProductNo homologues found for original id L:516
ATPMetaboliteC00002 (KEGG Compound)
Atp5a1GeneProductENSMUSG00000025428 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:498
Atp5bGeneProductENSMUSG00000025393 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:506
Atp5c1GeneProductENSMUSG00000025781 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:509
Atp5dGeneProductENSMUSG00000003072 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:513
Atp5eGeneProductENSMUSG00000016252 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:514
Atp5f1GeneProductENSMUSG00000000563 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:515
Atp5g2GeneProductENSMUSG00000062683 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:517
Atp5g3GeneProductENSMUSG00000018770 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:518
Atp5hGeneProductENSMUSG00000034566 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:10476
Atp5j2GeneProductENSMUSG00000038690 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9551
Atp5jGeneProductENSMUSG00000022890 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:522
Atp5kGeneProductENSMUSG00000050856 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:521
Atp5lGeneProductENSMUSG00000038717 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:10632
Atp5oGeneProductENSMUSG00000022956 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:539
Atp5sGeneProductENSMUSG00000054894 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:27109
Atpif1GeneProductENSMUSG00000054428 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:93974
COX11GeneProductMultiple homologues found: En:ENSMUSG00000020541;En:ENSMUSG00000020544;
COX7A3GeneProduct
COX7CGeneProduct
Cox15GeneProductENSMUSG00000040018 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1355
Cox17GeneProductENSMUSG00000046516 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:10063
Cox4i1GeneProductENSMUSG00000031818 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1327
Cox5aGeneProductENSMUSG00000000088 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9377
Cox5bGeneProductENSMUSG00000061518 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1329
Cox6a1GeneProductENSMUSG00000041697 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1337
Cox6a2GeneProductENSMUSG00000030785 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1339
Cox6b1GeneProductENSMUSG00000036751 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1340
Cox6cGeneProductENSMUSG00000014313 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1345
Cox7a1GeneProductENSMUSG00000074218 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1346
Cox7a2GeneProductENSMUSG00000032330 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1347
Cox7a2lGeneProductENSMUSG00000024248 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9167
Cox7bGeneProductENSMUSG00000031231 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1349
Cox8aGeneProductENSMUSG00000035885 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:1351
Cytochrome CMetaboliteC00524 (KEGG Compound)
FADMetaboliteC00016 (KEGG Compound)
FADH2MetaboliteC01352 (KEGG Compound)
Gm20538GeneProductENSMUSG00000091471 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4714
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteHMDB0002111 (HMDB)
NAD+MetaboliteC00003 (KEGG Compound)
NADHMetaboliteC00004 (KEGG Compound)
NDUFB1GeneProductNo homologues found for original id L:4707
Ndufa10GeneProductENSMUSG00000026260 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4705
Ndufa12GeneProductENSMUSG00000020022 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:55967
Ndufa1GeneProductENSMUSG00000016427 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4694
Ndufa2GeneProductENSMUSG00000014294 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4695
Ndufa3GeneProductENSMUSG00000035674 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4696
Ndufa4GeneProductENSMUSG00000029632 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4697
Ndufa5GeneProductENSMUSG00000023089 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4698
Ndufa6GeneProductENSMUSG00000022450 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4700
Ndufa7GeneProductENSMUSG00000041881 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4701
Ndufa8GeneProductENSMUSG00000026895 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4702
Ndufa9GeneProductENSMUSG00000000399 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4704
Ndufab1GeneProductENSMUSG00000030869 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4706
Ndufb10GeneProductENSMUSG00000040048 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4716
Ndufb2GeneProductENSMUSG00000002416 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4708
Ndufb3GeneProductENSMUSG00000026032 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4709
Ndufb4GeneProductENSMUSG00000022820 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4710
Ndufb5GeneProductENSMUSG00000027673 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4711
Ndufb6GeneProductENSMUSG00000071014 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4712
Ndufb7GeneProductENSMUSG00000033938 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4713
Ndufb9GeneProductENSMUSG00000022354 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4715
Ndufc1GeneProductENSMUSG00000037152 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4717
Ndufc2GeneProductENSMUSG00000030647 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4718
Ndufs1GeneProductENSMUSG00000025968 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4719
Ndufs2GeneProductENSMUSG00000013593 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4720
Ndufs3GeneProductENSMUSG00000005510 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4722
Ndufs4GeneProductENSMUSG00000021764 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4724
Ndufs5GeneProductENSMUSG00000028648 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4725
Ndufs6GeneProductENSMUSG00000021606 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4726
Ndufs7GeneProductENSMUSG00000020153 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:374291
Ndufs8GeneProductENSMUSG00000059734 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4728
Ndufv1GeneProductENSMUSG00000037916 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4723
Ndufv2GeneProductENSMUSG00000024099 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4729
Ndufv3GeneProductENSMUSG00000024038 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4731
O2MetaboliteHMDB0001377 (HMDB)
SLC25A6GeneProductNo homologues found for original id L:293
Sco1GeneProductENSMUSG00000069844 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6341
SdhaGeneProductENSMUSG00000021577 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6389
SdhbGeneProductENSMUSG00000009863 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6390
SdhcGeneProductENSMUSG00000058076 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6391
SdhdGeneProductENSMUSG00000000171 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6392
Slc25a14GeneProductENSMUSG00000031105 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9016
Slc25a27GeneProductENSMUSG00000023912 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:9481
Slc25a4GeneProductENSMUSG00000031633 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:291
Slc25a5GeneProductENSMUSG00000016319 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:292
SuccinateMetaboliteC00042 (KEGG Compound)
Surf1GeneProductENSMUSG00000015790 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:6834
TCA CyclePathwayWP78 (WikiPathways)
UbiquinoneMetaboliteHMDB0002012 (HMDB)
Ucp1GeneProductENSMUSG00000031710 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7350
Ucp2GeneProductENSMUSG00000033685 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7351
Ucp3GeneProductENSMUSG00000032942 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7352
Uqcr10GeneProductENSMUSG00000059534 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:29796
Uqcr11GeneProductENSMUSG00000020163 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:10975
UqcrbGeneProductENSMUSG00000021520 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7381
Uqcrc1GeneProductENSMUSG00000025651 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7384
Uqcrc2GeneProductENSMUSG00000030884 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7385
Uqcrfs1GeneProductENSMUSG00000038462 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7386
UqcrhGeneProductENSMUSG00000063882 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:7388
UqcrqGeneProductENSMUSG00000044894 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:27089
e-MetaboliteC05359 (KEGG Compound)
mt-Atp6GeneProductENSMUSG00000064357 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4508
mt-Atp8GeneProductENSMUSG00000064356 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4509
mt-Co1GeneProductENSMUSG00000064351 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4512
mt-Co2GeneProductENSMUSG00000064354 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4513
mt-Co3GeneProductENSMUSG00000064358 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4514
mt-CytbGeneProductENSMUSG00000064370 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4519
mt-Nd1GeneProductENSMUSG00000064341 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4535
mt-Nd2GeneProductENSMUSG00000064345 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4536
mt-Nd3GeneProductENSMUSG00000064360 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4537
mt-Nd4GeneProductENSMUSG00000064363 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4538
mt-Nd4lGeneProductENSMUSG00000065947 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4539
mt-Nd5GeneProductENSMUSG00000064367 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4540
mt-Nd6GeneProductENSMUSG00000064368 (Ensembl) Homology Mapping from Homo sapiens to Mus musculus: Original ID = L:4541

Annotated Interactions

No annotated interactions
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