SARS-CoV-2 altering angiogenesis via NRP1 (Homo sapiens)

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Bibliography

1. Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C, Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM, Cullen PJ, Yamauchi Y; ''Neuropilin-1 is a host factor for SARS-CoV-2 infection.''; Science, 2020 PubMed Europe PMC Scholia
2. Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M; ''Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor.''; Cell, 1998 PubMed Europe PMC Scholia
3. Mayi BS, Leibowitz JA, Woods AT, Ammon KA, Liu AE, Raja A; ''The role of Neuropilin-1 in COVID-19.''; PLoS Pathog, 2021 PubMed Europe PMC Scholia
4. McFarland AJ, Yousuf MS, Shiers S, Price TJ; ''Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain.''; Pain Rep, 2021 PubMed Europe PMC Scholia
5. Li ZL, Buck M; ''Neuropilin-1 Assists SARS-CoV-2 Infection by Stimulating the Separation of Spike Protein Domains S1 and S2.''; bioRxiv, 2021 PubMed Europe PMC Scholia
6. Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R; ''SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia.''; bioRxiv, 2020 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
ACE2	GeneProduct	ENSG00000130234 (Ensembl)
Angiogenesis	Pathway	WP1993 (WikiPathways)
FURIN	GeneProduct	ENSG00000140564 (Ensembl)
KDR	GeneProduct	ENSG00000128052 (Ensembl)
Membrane fusion	Pathway	Q6556360 (Wikidata)
NRP1	GeneProduct	ENSG00000099250 (Ensembl)
S1
S2
Surface glycoprotein S	Protein	P0DTC2 (Uniprot-TrEMBL)
VEGFA	GeneProduct	ENSG00000112715 (Ensembl)

Annotated Interactions

No annotated interactions