TCA cycle - detailed (Saccharomyces cerevisiae)
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Khanspers
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CO2
succinyl-lipoate
H2O
dihydrolipoyl-oxo-glut-e2
isocitrate
H2O
H+
H2O
ubiquinol (30)
cis-aconitrate
dihydrolipoyl-oxo-glut-e2
2-oxoglutarate
fumarate
oxaloacetic acid
succinate
pyruvate
citrate
CO2
H2O
NAD
HCO3-
CO2
NAD
succinyl-CoA ligase 2
malate
succinate dehydrogenase 1
succinyl-CoA
ADP
aconitase
malate dehydrogenase
isocitrate dehydrogenase 1
NADH
succinate dehydrogenase 2
cytoplasmic malate dehydrogenase
NADH
isocitrate dehydrogenase 2
mitochondrial malate dehydrogenase
citrate synthase 3
pyruvate carboxylase 1
phosphate
aconitase
Coenzyme A
ATP
alpha-ketoglutarate dehydrogenase
ADP
Coenzyme A
ubiquinone (30)
pyruvate carboxylase 2
phosphate
citrate synthase 1
succinate dehydrogenase 3
Dihydrolipoamide transsuccinylase
succinyl-CoA ligase 1
citrate synthase 2
fumarate hydratase
ATP
succinate dehydrogenase 4
aconitate hydratase
acetyl-CoA
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Bibliography
''TCA cycle, aerobic respiration ''; YeastPathways,
History
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Revision
Action
Time
User
Comment
135687
view
23:59, 22 October 2024
Khanspers
Ontology Term : 'energy metabolic pathway' added !
135686
view
23:57, 22 October 2024
Khanspers
Modified description
135685
view
23:55, 22 October 2024
Khanspers
updated reference
135684
view
23:55, 22 October 2024
Khanspers
overhaul
117347
view
11:53, 20 May 2021
Eweitz
Modified title
102417
view
09:57, 23 December 2018
Egonw
Replaced a deleted CAS number with the active one.
76239
view
17:22, 20 June 2014
MaintBot
Modified title
71338
view
18:01, 17 October 2013
MaintBot
Automated update of data sources
67691
view
11:49, 26 June 2013
Ddigles
Ontology Term : 'citrate cycle pathway' added !
62168
view
12:05, 25 April 2013
Egonw
Converted labels into Metabolite DataNode's.
62167
view
12:01, 25 April 2013
Egonw
Connected some dots.
41807
view
04:48, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34361
view
22:30, 9 December 2009
MaintBot
Automatic update of empty xrefs
29181
view
18:13, 9 April 2009
Khanspers
Changed name
21303
view
11:31, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:TCA cycle]] moved to [[Pathway:WP296]]: Moved to stable identifier
12865
view
08:06, 17 May 2008
MaintBot
automated metabolite conversion
8954
view
14:13, 7 January 2008
MaintBot
Added to category $category
8952
view
14:13, 7 January 2008
J.Heckman
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
2-oxoglutarate
Metabolite
ADP
Metabolite
58-64-0 (CAS)
ATP
Metabolite
1927-31-7 (CAS)
CO2
Metabolite
Coenzyme A
Metabolite
64885-97-8 (CAS)
Dihydrolipoamide transsuccinylase
GeneProduct
S000002555 (SGD)
H+
Metabolite
H2O
Metabolite
HCO3-
Metabolite
NAD
Metabolite
NADH
Metabolite
53-84-9 (CAS)
acetyl-CoA
Metabolite
72-89-9 (CAS)
aconitase
GeneProduct
S000004295 (SGD)
aconitate hydratase
GeneProduct
S000003736 (SGD)
alpha-ketoglutarate dehydrogenase
GeneProduct
S000001387 (SGD)
cis-aconitrate
Metabolite
citrate
Metabolite
citrate synthase 1
GeneProduct
S000005284 (SGD)
citrate synthase 2
GeneProduct
S000000598 (SGD)
citrate synthase 3
GeneProduct
S000006205 (SGD)
cytoplasmic malate dehydrogenase
GeneProduct
S000005486 (SGD)
dihydrolipoyl-oxo-glut-e2
Metabolite
fumarate
Metabolite
fumarate hydratase
GeneProduct
S000006183 (SGD)
isocitrate
Metabolite
isocitrate dehydrogenase 1
GeneProduct
S000004982 (SGD)
isocitrate dehydrogenase 2
GeneProduct
S000005662 (SGD)
malate dehydrogenase
GeneProduct
S000002236 (SGD)
malate
Metabolite
6915-15-7 (CAS)
mitochondrial malate dehydrogenase
GeneProduct
S000001568 (SGD)
oxaloacetic acid
Metabolite
phosphate
Metabolite
14265-44-2 (CAS)
pyruvate
Metabolite
pyruvate carboxylase 1
GeneProduct
S000003030 (SGD)
pyruvate carboxylase 2
GeneProduct
S000000422 (SGD)
succinate
Metabolite
succinate dehydrogenase 1
GeneProduct
S000001631 (SGD)
succinate dehydrogenase 2
GeneProduct
S000003964 (SGD)
succinate dehydrogenase 3
GeneProduct
S000001624 (SGD)
succinate dehydrogenase 4
GeneProduct
S000002585 (SGD)
succinyl-CoA ligase 1
GeneProduct
S000005668 (SGD)
succinyl-CoA ligase 2
GeneProduct
S000003476 (SGD)
succinyl-CoA
Metabolite
604-98-8 (CAS)
succinyl-lipoate
Metabolite
ubiquinol (30)
Metabolite
ubiquinone (30)
Metabolite
303-97-9 (CAS)
Annotated Interactions
No annotated interactions
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