Burn wound healing (Mus musculus)

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Col1a1Nos3Tgfbrap1Pecam1Fn1Lama1TnfNOVegfaL-HydroxyprolinePDRNHbegfEPOTgfb11, 7, 83, 7, 12, 1351, 135Nos21212, 13121212, 137, 12131, 8312, 13Flii4Acta16, 8, 12Gja110Prodh26Upregulated GenesUp-& Down-regulated GenesIl6Ccl27Fgf277S100a8Nlrp377Il1b7Il187TP539CCND111


Description

Burn Wound Healing

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Ontology Terms

 

Bibliography

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  1. Yang L, Chan T, Demare J, Iwashina T, Ghahary A, Scott PG, Tredget EE; ''Healing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermis.''; Am J Pathol, 2001 PubMed Europe PMC Scholia
  2. ''Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury''; Biol.Open, 2016 PubMed Europe PMC Scholia
  3. Galeano M, Deodato B, Altavilla D, Squadrito G, Seminara P, Marini H, Stagno d'Alcontres F, Colonna M, Calò M, Lo Cascio P, Torre V, Giacca M, Venuti FS, Squadrito F; ''Effect of recombinant adeno-associated virus vector-mediated vascular endothelial growth factor gene transfer on wound healing after burn injury.''; Crit Care Med, 2003 PubMed Europe PMC Scholia
  4. Cameron AM, Turner CT, Adams DH, Jackson JE, Melville E, Arkell RM, Anderson PJ, Cowin AJ; ''Flightless I is a key regulator of the fibroproliferative process in hypertrophic scarring and a target for a novel antiscarring therapy.''; Br J Dermatol, 2016 PubMed Europe PMC Scholia
  5. Cribbs RK, Harding PA, Luquette MH, Besner GE; ''Endogenous production of heparin-binding EGF-like growth factor during murine partial-thickness burn wound healing.''; J Burn Care Rehabil, 2002 PubMed Europe PMC Scholia
  6. Davis TA, Amare M, Naik S, Kovalchuk AL, Tadaki D; ''Differential cutaneous wound healing in thermally injured MRL/MPJ mice.''; Wound Repair Regen, 2007 PubMed Europe PMC Scholia
  7. Vinaik R, Abdullahi A, Barayan D, Jeschke MG; ''NLRP3 inflammasome activity is required for wound healing after burns.''; Transl Res, 2020 PubMed Europe PMC Scholia
  8. Cameron AM, Turner CT, Adams DH, Jackson JE, Melville E, Arkell RM, Anderson PJ, Cowin AJ; ''Flightless I is a key regulator of the fibroproliferative process in hypertrophic scarring and a target for a novel antiscarring therapy.''; Br J Dermatol, 2016 PubMed Europe PMC Scholia
  9. Nagata M, Takenaka H, Shibagaki R, Kishimoto S; ''Apoptosis and p53 protein expression increase in the process of burn wound healing in guinea-pig skin.''; Br J Dermatol, 1999 PubMed Europe PMC Scholia
  10. Coutinho P, Qiu C, Frank S, Wang CM, Brown T, Green CR, Becker DL; ''Limiting burn extension by transient inhibition of Connexin43 expression at the site of injury.''; Br J Plast Surg, 2005 PubMed Europe PMC Scholia
  11. DeCherney AH, Dougherty WR, Felix JC, Rodgers KE, Girgis W, Abiko M, diZerega GS; ''Expression of cyclin protein after thermal skin injury in a guinea pig model.''; J Burn Care Rehabil, 1997 PubMed Europe PMC Scholia
  12. Bitto A, Galeano M, Squadrito F, Minutoli L, Polito F, Dye JF, Clayton EA, Calò M, Venuti FS, Vaccaro M, Altavilla D; ''Polydeoxyribonucleotide improves angiogenesis and wound healing in experimental thermal injury.''; Crit Care Med, 2008 PubMed Europe PMC Scholia
  13. Galeano M, Altavilla D, Bitto A, Minutoli L, Calò M, Lo Cascio P, Polito F, Giugliano G, Squadrito G, Mioni C, Giuliani D, Venuti FS, Squadrito F; ''Recombinant human erythropoietin improves angiogenesis and wound healing in experimental burn wounds.''; Crit Care Med, 2006 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
134368view13:13, 21 July 2024EgonwAdded missing info for a reference
134367view13:11, 21 July 2024EgonwFixed the XML of several references
134365view13:08, 21 July 2024EgonwRemoved template comments
119775view12:38, 20 August 2021EweitzModified title
119623view17:56, 21 July 2021Egonwupdated a resource
119584view07:17, 21 July 2021ExperiMedModified description
119559view11:44, 15 July 2021ExperiMedOntology Term : 'myofibroblast cell' added !
119558view11:43, 15 July 2021ExperiMedOntology Term : 'immune response pathway' added !
119557view11:43, 15 July 2021ExperiMedOntology Term : 'keratinocyte' added !
119556view11:43, 15 July 2021ExperiMedOntology Term : 'endothelial cell' added !
119555view11:42, 15 July 2021ExperiMedOntology Term : 'fibroblast' added !
119554view11:42, 15 July 2021ExperiMedOntology Term : 'cell-extracellular matrix signaling pathway' added !
119553view11:40, 15 July 2021ExperiMedFixed Interaction and Annotation.
116242view17:17, 21 April 2021EgonwUse Uniprot-TrEMBL instead of Uniprot-SwissProt
115637view09:57, 3 March 2021ExperiMedadded full references
115583view10:16, 1 March 2021ExperiMedadded TP53 and CCND1 from cavia porcellus (guinea pig) to the mus musculus patwhay.)
115392view16:42, 17 February 2021ExperiMedremoved some comments
115374view16:30, 16 February 2021ExperiMedNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Acta1ProteinP68134 (Uniprot-TrEMBL)
CCND1ProteinA0A286XN48 (Uniprot-TrEMBL) Cavia Percellus
Ccl2RnaENSMUSG00000035385 (Ensembl)
Col1a1ProteinP11087 (Uniprot-TrEMBL)
EPOProteinP01588 (Uniprot-TrEMBL)
Fgf2RnaENSMUSG00000037225 (Ensembl)
FliiProteinQ9JJ28 (Uniprot-TrEMBL)
Fn1ProteinP02751 (Uniprot-TrEMBL)
Gja1ProteinP23242 (Uniprot-TrEMBL) Type your comment here
HbegfProteinQ06186 (Uniprot-TrEMBL)
Il18RnaENSMUSG00000039217 (Ensembl)
Il1bRnaENSMUSG00000027398 (Ensembl)
Il6RnaENSMUSG00000025746 (Ensembl)
L-HydroxyprolineMetaboliteC01157 (KEGG Genes)
Lama1ProteinP19137 (Uniprot-TrEMBL)
NOMetaboliteC00533 (KEGG Drug)
Nlrp3ProteinQ8R4B8 (Uniprot-TrEMBL)
Nos2ProteinP29477 (Uniprot-TrEMBL)
Nos3ProteinP70313 (Uniprot-TrEMBL)
PDRNProteinP37913 (Uniprot-SwissProt)
  • Polydeoxyribonucleotide (PDRN)
  • Protein-ID might be incorrect, as the manuscript does not specify the compound for treatment
Pecam1ProteinQ08481 (Uniprot-TrEMBL)
Prodh2ProteinQ8VCZ9 (Uniprot-TrEMBL)
  • Hydroxyproline
  • Type your comment here
S100a8RnaENSMUSG00000056054 (Ensembl)
TP53ProteinQ9WUR6 (Uniprot-TrEMBL) Cavia Percellus
Tgfb1ProteinP04202 (Uniprot-TrEMBL)
Tgfbrap1ProteinQ3UR70 (Uniprot-TrEMBL)
TnfProteinP06804 (Uniprot-TrEMBL)
VegfaProteinQ00731 (Uniprot-TrEMBL)

Annotated Interactions

No annotated interactions

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