Iron-sulfur cluster biogenesis (Homo sapiens)

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21Mitochondrial Fe-S proteinsFXNISCUL-cysteineLYRM4FeNFU1NFS1S[4Fe-4S] clustere-FDX1FDXRABCB7HSPA9HSCBGLRX5NUBP2NUBP1NARFCIAO1FAM96BFXNNFU1NFS1ISCUFeFeFe[4Fe-4S] clusterCytosolicFe-S proteinsISCU


Description

draft

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Quality Tags

Ontology Terms

 

Bibliography

  1. Friemel M, Marelja Z, Li K, Leimkühler S; ''The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1.''; Biochemistry, 2017 PubMed Europe PMC Scholia
  2. Rouault TA, Tong WH; ''Iron-sulfur cluster biogenesis and human disease.''; Trends Genet, 2008 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
125997view18:20, 24 March 2023KhanspersOntology Term : 'regulatory pathway' added !
125989view18:12, 23 March 2023KhanspersModified description
125986view18:06, 23 March 2023Khansperslatest - updated xrefs
125985view18:04, 23 March 2023KhanspersReverted to version '17:47, 23 March 2023' by Khanspers
125984view18:03, 23 March 2023Khansperslatest - updated xrefs
125983view17:47, 23 March 2023KhanspersModified description
125982view17:31, 23 March 2023KhanspersModified description
125981view17:31, 23 March 2023Khanspersupdate with latest
120555view00:20, 15 December 2021KhanspersOntology Term : 'iron-sulfur cluster protein biogenesis pathway' added !
120554view00:19, 15 December 2021KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABCB7GeneProductENSG00000131269 (Ensembl)
CIAO1GeneProductENSG00000144021 (Ensembl)
FAM96BGeneProductENSG00000166595 (Ensembl)
FDX1GeneProductENSG00000137714 (Ensembl)
FDXRGeneProductENSG00000161513 (Ensembl)
FXNGeneProductENSG00000165060 (Ensembl)
FeMetaboliteCHEBI:18248 (ChEBI)
GLRX5GeneProductENSG00000182512 (Ensembl)
HSCBGeneProductENSG00000100209 (Ensembl)
HSPA9GeneProductENSG00000113013 (Ensembl)
ISCUGeneProductENSG00000136003 (Ensembl)
L-cysteineMetaboliteCHEBI:17561 (ChEBI)
LYRM4GeneProductENSG00000214113 (Ensembl)
NARFGeneProductENSG00000141562 (Ensembl)
NFS1GeneProductENSG00000244005 (Ensembl)
NFU1GeneProductENSG00000169599 (Ensembl)
NUBP1GeneProductENSG00000103274 (Ensembl)
NUBP2GeneProductENSG00000095906 (Ensembl)
SMetaboliteCHEBI:26833 (ChEBI)
[4Fe-4S] clusterMetaboliteCHEBI:49883 (ChEBI)
e-MetaboliteCHEBI:10545 (ChEBI)

Annotated Interactions

No annotated interactions

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