Fatty acid biosynthesis (Bos taurus)

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Malonyl-ACP3-ketoacyl-CoATCA CycleCitrate3-L-Hydroxyacyl-CoACrotonoyl-ACPCytosolAcetoacetyl-ACPOxaloacetateFatty acyl CoALong-Chain fatty acidtrans-delta2-enoyl-CoAPyruvateMitochondrionbeta-hydroxybutyryl6 iterationsPalmitateButyryl-ACPless than 6 iterationsAcetyl-synthasePalmitoyl-ACPAcetyl-ACPACACBFASNPCAcetyl-CoAACAA2ACACAFASNPECRFASNACLYFASNDECR1ECHS1FASNFASNFASNMECRTriacylglyceride Synthesis pathwayHADHECH1ACSL5Malonyl-CoAACSL4ECHDC1ECHDC2FASNSCDAcyl-CoA (n+2)ECHDC3ACSL3ACSL6ACSS2ACSL1


Description

Fatty acid synthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP357(70641) with a 96.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
125343view19:38, 3 February 2023AlexanderPicoModified description
125091view23:21, 20 January 2023AlexanderPicofixed typo
125090view23:20, 20 January 2023AlexanderPicoadded description
124922view22:47, 31 December 2022EgonwFixed the AcylCoA identifier
120929view08:06, 1 February 2022EgonwMade two pathways clickable
117511view11:06, 21 May 2021EweitzModified title
80794view15:26, 30 June 2015Mkutmonhomology conversion
79158view05:09, 6 March 2015MaintBotModified description
79157view05:08, 6 March 2015MaintBotUpdated conversion from Hs
71425view19:02, 17 October 2013MaintBotAutomated update of data sources
63446view17:14, 10 May 2013MaintBotUpdated to 2013 gpml schema
40580view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33817view00:23, 9 December 2009MaintBotAutomatic update of empty xrefs
31661view11:39, 14 August 2009MaintBotFixed group labels
30589view22:12, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACAA2GeneProductENSBTAG00000002863 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10449
ACACAGeneProduct
ACACBGeneProductENSBTAG00000022058 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:32
ACLYGeneProductENSBTAG00000016740 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:47
ACSL1GeneProductENSBTAG00000004344 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2180
ACSL3GeneProductENSBTAG00000017258 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2181
ACSL4GeneProductENSBTAG00000018986 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2182
ACSL5GeneProductENSBTAG00000006707 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51703
ACSL6GeneProductENSBTAG00000019708 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23305
ACSS2GeneProductENSBTAG00000013303 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55902
Acetyl-CoAMetabolite72-89-9 (CAS)
Acyl-CoA (n+2)MetaboliteCHEBI:17984 (ChEBI)
CitrateMetabolite29081 (Chemspider)
DECR1GeneProductENSBTAG00000019663 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1666
ECH1GeneProductENSBTAG00000016313 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1891
ECHDC1GeneProductENSBTAG00000003887 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55862
ECHDC2GeneProductENSBTAG00000002910 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55268
ECHDC3GeneProductENSBTAG00000012377 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:79746
ECHS1GeneProductENSBTAG00000017710 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1892
FASNGeneProductENSBTAG00000015980 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2194
HADHGeneProductENSBTAG00000002049 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3033
Long-Chain fatty acidMetaboliteCHEBI:15904 (ChEBI)
MECRGeneProductENSBTAG00000017253 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51102
Malonyl-CoAMetabolite524-14-1 (CAS)
OxaloacetateMetabolite2509917 (Chemspider)
PCGeneProductENSBTAG00000019700 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
PECRGeneProductENSBTAG00000006821 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55825
PalmitateMetabolite440215 (Chemspider)
PyruvateMetabolite96901 (Chemspider)
SCDGeneProductENSBTAG00000047957 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6319
TCA CyclePathwayWP78 (WikiPathways)
Triacylglyceride Synthesis pathwayPathwayWP325 (WikiPathways)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1020"
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