SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Yi F, Wang Z, Liu J, Zhang Y, Xu H, Li X, Bai N, Cao L, Song X; ''Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis.''; Int J Biol Sci, 2017 PubMed Europe PMC Scholia
2. Litwin I, Pilarczyk E, Wysocki R; ''The Emerging Role of Cohesin in the DNA Damage Response.''; Genes (Basel), 2018 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	129308	view	13:49, 26 March 2024	Mkutmon	Ontology Term : 'disease pathway' added !
	125319	view	21:50, 31 January 2023	Larsgw	Fix reference bp:ID
	119397	view	10:49, 27 June 2021	Eweitz	Ontology Term : 'Cornelia de Lange syndrome' added !
	119396	view	10:49, 27 June 2021	Eweitz	Modified title
	119108	view	12:37, 17 June 2021	IrkilmezA	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
ATM	GeneProduct	ENSG00000149311 (Ensembl)	While SMC1A is specifically phosphorylated by phosphorylated ATM, no information was found on if the same applies to SMC3.
BRCA1	GeneProduct	ENSG00000012048 (Ensembl)
MDC1	GeneProduct	ENSG00000137337 (Ensembl)
MRE11	GeneProduct	ENSG00000020922 (Ensembl)
NBN	GeneProduct	ENSG00000104320 (Ensembl)
PAXIP1	GeneProduct	ENSG00000157212 (Ensembl)
RAD18	GeneProduct	ENSG00000070950 (Ensembl)
RAD21	GeneProduct	ENSG00000164754 (Ensembl)
RAD50	GeneProduct	ENSG00000113522 (Ensembl)
SMC1A	GeneProduct	ENSG00000072501 (Ensembl)
SMC3	GeneProduct	ENSG00000108055 (Ensembl)

Annotated Interactions

No annotated interactions