Cancer pathways (Homo sapiens)

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Revision as of 22:58, 2 January 2024 by Khanspers (Talk | contribs)
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MicrotubuleMitochondriaWntCarcinogensDNA damageOxidative or electrophilic stressLigands?SustainedangiogenesisCytokine receptorRARatarget genesPU.1 target genesTelomeric DNA repeatsPIK3CAFGF1RBX1TERCEGFRTERTELOBARHGEF12ETS1PTK2MDM2PLD1CASP3CTNNA1RASSF1SOS1mTOR signalingpathwayBAXPAKLK3EDNRADAPK1BADCTNNB1SKP1CTBP1Notch signaling pathwayHDAC1FLT4TGFAIGF1RCCNE1TP53FLT3LGCDKN1BCASP8EPAS1TGFBR2CALML1CXCL8NOTCH1CDKN1AEstradiolELOCSTAT1RARBSMAD2PI3K-Aktsignaling pathwayARNTCREBBPPPAR signalingpathwayMAPK8DCCMYCPTENCCNA2APAF1cAMPFGFR1PMLHMOX1Focal adhesionDVL1Hydroperoxyl radicalMMP1GNASSPI1MYCEGFCHUKGADD45GABL1VEGF signalingpathwayJak-STAT signaling pathwayJUNELK1NKX3-1PLCB1RUNX1RAD51EstradiolSMOGNA11PRKCAITGB1PGE2PDGFBRB1CXCR4LEF1RETROCK1TGFBR2JUPEGLN2Hydroxyl radicalCAMK2ATRAF1BAXfumarateFRAT1Hydrogen peroxideMTORLRP5BAK1CYCScAMP signalingpathwayNitric oxidePPARGIP3HEY1MSH2PTGER1SKP2AXIN1GSK3BCDKN1BDNACCND1GNB5FLT3MAPK signalingpathwayLPAR6CholesterolBIRC5METMYCHIF-1 signalingpathwaySTAT5AFASLGApoptosisCRKRHOATestosteroneRXRACCND1CDKN1AProgesteroneCDKN2BGRB2CASP9ITGA6F2CKS1BFOXO1BCL2L11FHKIF7BRCA2CCND1BADESR1RPS6KB1TGFB1PRKACAKEAP1SPI1BMP2BIRC2RPS6KA5AGTGSTP1RASSF5JAG1BCL2RALAWnt signalingpathwayBBC3TGF-beta signalingpathwayBAK1CUL2TP53PLCG1MITFCSF3RAPPL1TGFAp53 signalingpathwayTGFBR1JAK1MECOMRASGRP1DehydroepiandrosteroneRALGDSDAGPPARDMLH1NQO1MSH6ERBB2RAC1HHIPSMAD4ARAFMAP2K1NFKB1FOSCDH1SUFUCDKN2AHES1NOS2DLL3KITBCL2L1Retinoic AcidGNAI1SuperoxideE2F1FADDRASSF1SLC2A1PDGFAEDN1WNT16VEGFDHSP90AA1VHLMSH3STAT3GLI1TXNRD1ARRALBP1CTNNB1CTNNB1RUNX1PTCH1CDK2PGFCalcium signalingpathwayRARAPIP3SHHPTGS2MAXAPC2PIM2MDM2MAPK1PTCH1Ca2+CASP9ADCY1BCL2PDGFRAHedgehog signaling pathwayCXCL12CASP3BCL2L1STAT2CSF2RAKITLGCDK4BIDIGF1CASP3ALKRHOAHRASTFGNFKBIACell cyclePOLKIL6GNA13FASMYCCDK4TGFB1CDKN2APMAIP1HGFIP3NCOA3DDB2Estrogen signalingpathwayCSF1RAdherens junctionNFE2L2CEBPAKNG1ZBTB17AcroleinJAG2PDLL4DLL1GLI2GLI3DihydrotestosteroneFlutamideAndrostenedioneCortisolCortisoneARHSP90AB1HSP90B1ARNOTCH2NOTCH3NOTCH4BMP4GLI1PTCH2HES5HEY2HEYLEGLN1EGLN3MalateHIF1AARNT2EP300VEGFAVEGFBVEGFCTGFB2TGFB34-HNETXNRD2TXNRD3CASP7Evaiding apoptosisMitochondriaTGFB2TGFB3SMAD3Genomic damageInsesitivity toanti-growth signalsResistance tochemotherapyImmortalityHDAC2CTBP2DNAGenomic instabilityGADD45BGADD45ACDK6CCND2CCND3E2F2E2F3ProliferationCCNE2RBX1CUL1CKS1BBlock ofdifferentiationE2F1E2F2E2F3CSF1RCSF1RC/EBPa target genesCEBPAAML1 target genesRARAZBTB16RUNX1RUNX1T1CCNA1CCND1TCF7TCF7L2TCF7L1SP1ESR2NCOA1ESR1ESR2EstradiolEstradiolRXRBRXRGRXRARXRBRXRGPPARGPAX8CCND1VEGFDVEGFAVEGFBVEGFCMMP2MMP3FOSMYCJUNMAPK3DAPK2DAPK3MAP2K2BRAFRAF1NRASKRASSOS2ERBB2PDGFRBFGFR2FGFR3FGFR4Cytokine IGF2PDGFBRALBPLD2RAC2RAC3MAPK9MAPK10RAC1RAC2RAC3CCDC42PLCG2EML4PRKCBPRKCGCCDC6NCOA4NTRK1TPM3TPRTissue invasion and metastasisCTNNA3CTNNA2AXIN2APCFRAT2DVL2DVL3MYCCCND1LEF1TCF7TCF7L2TCF7L1PGFVEGFDVEGFAVEGFBVEGFCLRP6PTGER2PTGER3PTGER4AGTR1LPAR1F2RLPAR2LPAR3LPAR4LPAR5F2RL3GNA12ARHGEF11ARHGEF1PLEKHG5ROCK2GNAI2GNAI3ADCY2ADCY3ADCY4ADCY5ADCY6ADCY7ADCY8ADCY9PRKACBPRKACGGNB1GNB2GNB3GNG3GNG4GNG5GNG7GNG10GNG11GNGT1BCL2L1PIM1BIRC3BIRC7XIAPTRAF2TRAF3TRAF4TRAF5TRAF6GNGT2GNG13GNG2GNG12GNG8GNB4ITGA2ITGA2BITGA3ITGAVEDNRBF2AGTBDKRB1BDKRB2GNAQPLCB2PLCB3PLCB4PRKCAPRKCBPRKCGCa2+DAGJAK2JAK3RASGRP2RASGRP3RASGRP4ALKEML4MST1STAT5BSTAT4STAT6BCRCBLCRKLPIK3CBPIK3CDPIK3R1PIK3R2PIK3R3AKT1AKT2AKT3IKBKBIKBKGNFKB2RELACASP9BCL2L1RPS6KB2CALML2CALML3CALML4CALML5CALML6CAMK2BCAMK2DCAMK2GWNT4WNT1WNT2WNT3WNT5AWNT6WNT7AWNT7BWNT8AWNT8BWNT10BWNT11WNT2BWNT9AWNT9BWNT10AWNT5BWNT3AFZD10FZD2FZD5FZD3FZD1FZD4FZD6FZD7FZD8FZD9LAMC3COL4A1COL4A2COL4A3COL4A4COL4A5COL4A6LAMB4FN1LAMA1LAMA2LAMA3LAMA4LAMA5LAMB1LAMB2LAMB3LAMC1LAMC2GSTO2GSTA5GSTA1GSTA2GSTA3GSTA4GSTM1GSTM2GSTM3GSTM4GSTM5GSTP1GSTT1GSTT2MGST1MGST2MGST3GSTT2BGSTO1


Description

draft pathway describing pathways in cancer

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. ''Pathways in cancer''; https://www.kegg.jp/dbget-bin/www_bget?pathway+hsa05200,

History

View all...
CompareRevisionActionTimeUserComment
135326view19:19, 21 August 2024Khanspersupdated kegg reference
135315view21:04, 19 August 2024Khanspersupdate KEGG ref
129459view01:04, 23 April 2024EweitzModified title
129136view16:45, 12 March 2024Khanspersminor tweak to test
128705view22:04, 20 February 2024EgonwMade a few pathways clickable
128257view00:14, 30 January 2024KhanspersModified description
128256view00:11, 30 January 2024Khanspersupdated lit ref
128254view00:08, 30 January 2024KhanspersOntology Term : 'cancer' added !
128253view00:08, 30 January 2024KhanspersOntology Term : 'altered signaling pathway' added !
128252view00:06, 30 January 2024Khanspersadded cell shape, legend, phospho sites
127898view00:17, 10 January 2024Khanspersnode sizing and layout
127897view00:08, 10 January 2024Khanspersadded cytokines and cytokine receptors
127896view22:57, 9 January 2024Khansperslayout
127895view22:51, 9 January 2024Khanspersadded wnts
127872view22:50, 3 January 2024Khansperslayout
127871view19:59, 3 January 2024Khansperscomplexes and interactions
127866view23:51, 2 January 2024Khanspersinteractions
127865view23:38, 2 January 2024Khanspersupdated interactions etc
127864view22:58, 2 January 2024Khansperslayout and interactions
127863view22:51, 2 January 2024Khanspersadded gst
127861view22:41, 2 January 2024Khanspersadded ecm
127859view22:33, 2 January 2024Khanspersadded wnt, fzd
127827view21:26, 21 December 2023KhanspersOntology Term : 'cancer pathway' added !
127826view21:25, 21 December 2023KhanspersModified title
127825view21:24, 21 December 2023KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
4-HNEMetaboliteC21642 (KEGG Compound)
ABL1GeneProductABL1 (HGNC)
ADCY1GeneProductADCY1 (HGNC)
ADCY2GeneProductADCY2 (HGNC)
ADCY3GeneProductADCY3 (HGNC)
ADCY4GeneProductADCY4 (HGNC)
ADCY5GeneProductADCY5 (HGNC)
ADCY6GeneProductADCY6 (HGNC)
ADCY7GeneProductADCY7 (HGNC)
ADCY8GeneProductADCY8 (HGNC)
ADCY9GeneProductADCY9 (HGNC)
AGTGeneProductAGT (HGNC)
AGTR1GeneProductAGTR1 (HGNC)
AKT1GeneProductAKT1 (HGNC)
AKT2GeneProductAKT2 (HGNC)
AKT3GeneProductAKT3 (HGNC)
ALKGeneProductALK (HGNC)
APAF1GeneProductAPAF1 (HGNC)
APC2GeneProductAPC2 (HGNC)
APCGeneProductAPC (HGNC)
APPL1GeneProductAPPL1 (HGNC)
ARAFGeneProductARAF (HGNC)
ARGeneProductAR (HGNC)
ARHGEF11GeneProductARHGEF11 (HGNC)
ARHGEF12GeneProductARHGEF12 (HGNC)
ARHGEF1GeneProductARHGEF1 (HGNC)
ARNT2GeneProductARNT2 (HGNC)
ARNTGeneProductARNT (HGNC)
AXIN1GeneProductAXIN1 (HGNC)
AXIN2GeneProductAXIN2 (HGNC)
AcroleinMetaboliteC01471 (KEGG Compound)
Adherens junctionPathway
AndrostenedioneMetaboliteHMDB00053 (HMDB)
ApoptosisPathwayWP254 (WikiPathways)
BADGeneProductBAD (HGNC)
BAK1GeneProductBAK1 (HGNC)
BAXGeneProductBAX (HGNC)
BBC3GeneProductBBC3 (HGNC)
BCL2GeneProductBCL2 (HGNC)
BCL2L11GeneProductBCL2L11 (HGNC)
BCL2L1GeneProductBCL2L1 (HGNC)
BCRGeneProductBCR (HGNC)
BDKRB1GeneProductBDKRB1 (HGNC)
BDKRB2GeneProductBDKRB2 (HGNC)
BIDGeneProductBID (HGNC)
BIRC2GeneProductBIRC2 (HGNC)
BIRC3GeneProductBIRC3 (HGNC)
BIRC5GeneProductBIRC5 (HGNC)
BIRC7GeneProductBIRC7 (HGNC)
BMP2GeneProductBMP2 (HGNC)
BMP4GeneProductBMP4 (HGNC)
BRAFGeneProductBRAF (HGNC)
BRCA2GeneProductBRCA2 (HGNC)
CALML1GeneProductCALML1 (HGNC)
CALML2GeneProductCALML2 (HGNC)
CALML3GeneProductCALML3 (HGNC)
CALML4GeneProductCALML4 (HGNC)
CALML5GeneProductCALML5 (HGNC)
CALML6GeneProductCALML6 (HGNC)
CAMK2AGeneProductCAMK2A (HGNC)
CAMK2BGeneProductCAMK2B (HGNC)
CAMK2DGeneProductCAMK2D (HGNC)
CAMK2GGeneProductCAMK2G (HGNC)
CASP3GeneProductCASP3 (HGNC)
CASP7GeneProductCASP7 (HGNC)
CASP8GeneProductCASP8 (HGNC)
CASP9GeneProductCASP9 (HGNC)
CBLGeneProductCBL (HGNC)
CCDC42GeneProductCCDC42 (HGNC)
CCDC6GeneProductCCDC6 (HGNC)
CCNA1GeneProductCCNA1 (HGNC)
CCNA2GeneProductCCNA2 (HGNC)
CCND1GeneProductCCND1 (HGNC)
CCND2GeneProductCCND2 (HGNC)
CCND3GeneProductCCND3 (HGNC)
CCNE1GeneProductCCNE1 (HGNC)
CCNE2GeneProductCCNE2 (HGNC)
CDH1GeneProductCDH1 (HGNC)
CDK2GeneProductCDK2 (HGNC)
CDK4GeneProductCDK4 (HGNC)
CDK6GeneProductCDK6 (HGNC)
CDKN1AGeneProductCDKN1A (HGNC)
CDKN1BGeneProductCDKN1B (HGNC)
CDKN2AGeneProductCDKN2A (HGNC)
CDKN2BGeneProductCDKN2B (HGNC)
CEBPAGeneProductCEBPA (HGNC)
CHUKGeneProductCHUK (HGNC)
CKS1BGeneProductCKS1B (HGNC)
COL4A1GeneProductCOL4A1 (HGNC)
COL4A2GeneProductCOL4A2 (HGNC)
COL4A3GeneProductCOL4A3 (HGNC)
COL4A4GeneProductCOL4A4 (HGNC)
COL4A5GeneProductCOL4A5 (HGNC)
COL4A6GeneProductCOL4A6 (HGNC)
CREBBPGeneProductCREBBP (HGNC)
CRKGeneProductCRK (HGNC)
CRKLGeneProductCRKL (HGNC)
CSF1RGeneProductCSF1R (HGNC)
CSF2RAGeneProductCSF2RA (HGNC)
CSF3RGeneProductCSF3R (HGNC)
CTBP1GeneProductCTBP1 (HGNC)
CTBP2GeneProductCTBP2 (HGNC)
CTNNA1GeneProductCTNNA1 (HGNC)
CTNNA2GeneProductCTNNA2 (HGNC)
CTNNA3GeneProductCTNNA3 (HGNC)
CTNNB1GeneProductCTNNB1 (HGNC)
CUL1GeneProductCUL1 (HGNC)
CUL2GeneProductCUL2 (HGNC)
CXCL12GeneProductCXCL12 (HGNC)
CXCL8GeneProductCXCL8 (HGNC)
CXCR4GeneProductCXCR4 (HGNC)
CYCSGeneProductCYCS (HGNC)
Ca2+MetaboliteCHEBI:29108 (ChEBI)
Calcium signaling pathwayPathway
Cell cyclePathwayWP179 (WikiPathways)
CholesterolMetaboliteHMDB00067 (HMDB)
CortisolMetaboliteHMDB00063 (HMDB)
CortisoneMetaboliteHMDB02802 (HMDB)
DAGMetaboliteC00165 (KEGG Compound)
DAPK1GeneProductDAPK1 (HGNC)
DAPK2GeneProductDAPK2 (HGNC)
DAPK3GeneProductDAPK3 (HGNC)
DCCGeneProductDCC (HGNC)
DDB2GeneProductDDB2 (HGNC)
DLL1GeneProductDLL1 (HGNC)
DLL3GeneProductDLL3 (HGNC)
DLL4GeneProductDLL4 (HGNC)
DNAMetaboliteCHEBI:16991 (ChEBI)
DVL1GeneProductDVL1 (HGNC)
DVL2GeneProductDVL2 (HGNC)
DVL3GeneProductDVL3 (HGNC)
DehydroepiandrosteroneMetaboliteHMDB00077 (HMDB)
DihydrotestosteroneMetaboliteHMDB02961 (HMDB)
E2F1GeneProductE2F1 (HGNC)
E2F2GeneProductE2F2 (HGNC)
E2F3GeneProductE2F3 (HGNC)
EDN1GeneProductEDN1 (HGNC)
EDNRAGeneProductEDNRA (HGNC)
EDNRBGeneProductEDNRB (HGNC)
EGFGeneProductEGF (HGNC)
EGFRGeneProductEGFR (HGNC)
EGLN1GeneProductEGLN1 (HGNC)
EGLN2GeneProductEGLN2 (HGNC)
EGLN3GeneProductEGLN3 (HGNC)
ELK1GeneProductELK1 (HGNC)
ELOBGeneProductELOB (HGNC)
ELOCGeneProductELOC (HGNC)
EML4GeneProductEML4 (HGNC)
EP300GeneProductEP300 (HGNC)
EPAS1GeneProductEPAS1 (HGNC)
ERBB2GeneProductERBB2 (HGNC)
ESR1GeneProductESR1 (HGNC)
ESR2GeneProductESR2 (HGNC)
ETS1GeneProductETS1 (HGNC)
EstradiolMetaboliteHMDB00151 (HMDB)
Estrogen signaling pathwayPathwayWP712 (WikiPathways)
F2GeneProductF2 (HGNC)
F2RGeneProductF2R (HGNC)
F2RL3GeneProductF2RL3 (HGNC)
FADDGeneProductFADD (HGNC)
FASGeneProductFAS (HGNC)
FASLGGeneProductFASLG (HGNC)
FGF1GeneProductFGF1 (HGNC)
FGFR1GeneProductFGFR1 (HGNC)
FGFR2GeneProductFGFR2 (HGNC)
FGFR3GeneProductFGFR3 (HGNC)
FGFR4GeneProductFGFR4 (HGNC)
FHGeneProductFH (HGNC)
FLT3GeneProductFLT3 (HGNC)
FLT3LGGeneProductFLT3LG (HGNC)
FLT4GeneProductFLT4 (HGNC)
FN1GeneProductFN1 (HGNC)
FOSGeneProductFOS (HGNC)
FOXO1GeneProductFOXO1 (HGNC)
FRAT1GeneProductFRAT1 (HGNC)
FRAT2GeneProductFRAT2 (HGNC)
FZD10GeneProductFZD10 (HGNC)
FZD1GeneProductFZD1 (HGNC)
FZD2GeneProductFZD2 (HGNC)
FZD3GeneProductFZD3 (HGNC)
FZD4GeneProductFZD4 (HGNC)
FZD5GeneProductFZD5 (HGNC)
FZD6GeneProductFZD6 (HGNC)
FZD7GeneProductFZD7 (HGNC)
FZD8GeneProductFZD8 (HGNC)
FZD9GeneProductFZD9 (HGNC)
FlutamideMetaboliteHMDB14642 (HMDB)
Focal adhesionPathwayWP306 (WikiPathways)
GADD45AGeneProductGADD45A (HGNC)
GADD45BGeneProductGADD45B (HGNC)
GADD45GGeneProductGADD45G (HGNC)
GLI1GeneProductGLI1 (HGNC)
GLI2GeneProductGLI2 (HGNC)
GLI3GeneProductGLI3 (HGNC)
GNA11GeneProductGNA11 (HGNC)
GNA12GeneProductGNA12 (HGNC)
GNA13GeneProductGNA13 (HGNC)
GNAI1GeneProductGNAI1 (HGNC)
GNAI2GeneProductGNAI2 (HGNC)
GNAI3GeneProductGNAI3 (HGNC)
GNAQGeneProductGNAQ (HGNC)
GNASGeneProductGNAS (HGNC)
GNB1GeneProductGNB1 (HGNC)
GNB2GeneProductGNB2 (HGNC)
GNB3GeneProductGNB3 (HGNC)
GNB4GeneProductGNB4 (HGNC)
GNB5GeneProductGNB5 (HGNC)
GNG10GeneProductGNG10 (HGNC)
GNG11GeneProductGNG11 (HGNC)
GNG12GeneProductGNG12 (HGNC)
GNG13GeneProductGNG13 (HGNC)
GNG2GeneProductGNG2 (HGNC)
GNG3GeneProductGNG3 (HGNC)
GNG4GeneProductGNG4 (HGNC)
GNG5GeneProductENSG00000174021 (Ensembl)
GNG7GeneProductGNG7 (HGNC)
GNG8GeneProductGNG8 (HGNC)
GNGT1GeneProductGNGT1 (HGNC)
GNGT2GeneProductGNGT2 (HGNC)
GRB2GeneProductGRB2 (HGNC)
GSK3BGeneProductGSK3B (HGNC)
GSTA1GeneProductGSTA1 (HGNC)
GSTA2GeneProductGSTA2 (HGNC)
GSTA3GeneProductGSTA3 (HGNC)
GSTA4GeneProductGSTA4 (HGNC)
GSTA5GeneProductGSTA5 (HGNC)
GSTM1GeneProductGSTM1 (HGNC)
GSTM2GeneProductGSTM2 (HGNC)
GSTM3GeneProductGSTM3 (HGNC)
GSTM4GeneProductGSTM4 (HGNC)
GSTM5GeneProductGSTM5 (HGNC)
GSTO1GeneProductGSTO1 (HGNC)
GSTO2GeneProductGSTO2 (HGNC)
GSTP1GeneProductGSTP1 (HGNC)
GSTT1GeneProductGSTT1 (HGNC)
GSTT2BGeneProductGSTT2B (HGNC)
GSTT2GeneProductGSTT2 (HGNC)
HDAC1GeneProductHDAC1 (HGNC)
HDAC2GeneProductHDAC2 (HGNC)
HES1GeneProductHES1 (HGNC)
HES5GeneProductHES5 (HGNC)
HEY1GeneProductHEY1 (HGNC)
HEY2GeneProductHEY2 (HGNC)
HEYLGeneProductHEYL (HGNC)
HGFGeneProductHGF (HGNC)
HHIPGeneProductHHIP (HGNC)
HIF-1 signaling pathwayPathway
HIF1AGeneProductHIF1A (HGNC)
HMOX1GeneProductHMOX1 (HGNC)
HRASGeneProductHRAS (HGNC)
HSP90AA1GeneProductHSP90AA1 (HGNC)
HSP90AB1GeneProductHSP90AB1 (HGNC)
HSP90B1GeneProductHSP90B1 (HGNC)
Hedgehog signaling pathwayPathwayWP4249 (WikiPathways)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
Hydroperoxyl radicalMetaboliteC21641 (ChEMBL compound)
Hydroxyl radicalMetaboliteC16844 (KEGG Compound)
IGF1GeneProductIGF1 (HGNC)
IGF1RGeneProductIGF1R (HGNC)
IGF2GeneProductIGF2 (HGNC)
IKBKBGeneProductIKBKB (HGNC)
IKBKGGeneProductIKBKG (HGNC)
IL6GeneProductIL6 (HGNC)
IP3MetaboliteC01245 (KEGG Compound)
ITGA2BGeneProductITGA2B (HGNC)
ITGA2GeneProductITGA2 (HGNC)
ITGA3GeneProductITGA3 (HGNC)
ITGA6GeneProductITGA6 (HGNC)
ITGAVGeneProductITGAV (HGNC)
ITGB1GeneProductITGB1 (HGNC)
JAG1GeneProductJAG1 (HGNC)
JAG2GeneProductJAG2 (HGNC)
JAK1GeneProductJAK1 (HGNC)
JAK2GeneProductJAK2 (HGNC)
JAK3GeneProductJAK3 (HGNC)
JUNGeneProductJUN (HGNC)
JUPGeneProductJUP (HGNC)
Jak-STAT signaling pathwayPathway
KEAP1GeneProductKEAP1 (HGNC)
KIF7GeneProductKIF7 (HGNC)
KITGeneProductKIT (HGNC)
KITLGGeneProductKITLG (HGNC)
KLK3GeneProductKLK3 (HGNC)
KNG1GeneProductKNG1 (HGNC)
KRASGeneProductKRAS (HGNC)
LAMA1GeneProductLAMA1 (HGNC)
LAMA2GeneProductLAMA2 (HGNC)
LAMA3GeneProductLAMA3 (HGNC)
LAMA4GeneProductLAMA4 (HGNC)
LAMA5GeneProductLAMA5 (HGNC)
LAMB1GeneProductLAMB1 (HGNC)
LAMB2GeneProductLAMB2 (HGNC)
LAMB3GeneProductLAMB3 (HGNC)
LAMB4GeneProductLAMB4 (HGNC)
LAMC1GeneProductLAMC1 (HGNC)
LAMC2GeneProductLAMC2 (HGNC)
LAMC3GeneProductLAMC3 (HGNC)
LEF1GeneProductLEF1 (HGNC)
LPAR1GeneProductLPAR1 (HGNC)
LPAR2GeneProductLPAR2 (HGNC)
LPAR3GeneProductLPAR3 (HGNC)
LPAR4GeneProductLPAR4 (HGNC)
LPAR5GeneProductLPAR5 (HGNC)
LPAR6GeneProductLPAR6 (HGNC)
LRP5GeneProductLRP5 (HGNC)
LRP6GeneProductLRP6 (HGNC)
MAP2K1GeneProductMAP2K1 (HGNC)
MAP2K2GeneProductMAP2K2 (HGNC)
MAPK signaling pathwayPathwayWP382 (WikiPathways)
MAPK10GeneProductMAPK10 (HGNC)
MAPK1GeneProductMAPK1 (HGNC)
MAPK3GeneProductMAPK3 (HGNC)
MAPK8GeneProductMAPK8 (HGNC)
MAPK9GeneProductMAPK9 (HGNC)
MAXGeneProductMAX (HGNC)
MDM2GeneProductMDM2 (HGNC)
MECOMGeneProductMECOM (HGNC)
METGeneProductMET (HGNC)
MGST1GeneProductMGST1 (HGNC)
MGST2GeneProductMGST2 (HGNC)
MGST3GeneProductMGST3 (HGNC)
MITFGeneProductMITF (HGNC)
MLH1GeneProductMLH1 (HGNC)
MMP1GeneProductMMP1 (HGNC)
MMP2GeneProductMMP2 (HGNC)
MMP3GeneProductMMP3 (HGNC)
MSH2GeneProductMSH2 (HGNC)
MSH3GeneProductMSH3 (HGNC)
MSH6GeneProductMSH6 (HGNC)
MST1GeneProductMST1 (HGNC)
MTORGeneProductMTOR (HGNC)
MYCGeneProductMYC (HGNC)
MalateMetaboliteCHEBI:30797 (ChEBI)
NCOA1GeneProductNCOA1 (HGNC)
NCOA3GeneProductNCOA3 (HGNC)
NCOA4GeneProductNCOA4 (HGNC)
NFE2L2GeneProductNFE2L2 (HGNC)
NFKB1GeneProductNFKB1 (HGNC)
NFKB2GeneProductNFKB2 (HGNC)
NFKBIAGeneProductNFKBIA (HGNC)
NKX3-1GeneProductNKX3-1 (HGNC)
NOS2GeneProductNOS2 (HGNC)
NOTCH1GeneProductNOTCH1 (HGNC)
NOTCH2GeneProductNOTCH2 (HGNC)
NOTCH3GeneProductNOTCH3 (HGNC)
NOTCH4GeneProductNOTCH4 (HGNC)
NQO1GeneProductNQO1 (HGNC)
NRASGeneProductNRAS (HGNC)
NTRK1GeneProductNTRK1 (HGNC)
Nitric oxideMetaboliteHMDB03378 (HMDB)
Notch signaling pathwayPathwayWP268 (WikiPathways)
PAMetaboliteC00416 (KEGG Compound)
PAX8GeneProductPAX8 (HGNC)
PDGFAGeneProductPDGFA (HGNC)
PDGFBGeneProductPDGFB (HGNC)
PDGFRAGeneProductPDGFRA (HGNC)
PDGFRBGeneProductPDGFRB (HGNC)
PGE2MetaboliteHMDB01220 (HMDB)
PGFGeneProductPGF (HGNC)
PI3K-Akt signaling pathwayPathwayWP4172 (KEGG Pathway)
PIK3CAGeneProductPIK3CA (HGNC)
PIK3CBGeneProductPIK3CB (HGNC)
PIK3CDGeneProductPIK3CD (HGNC)
PIK3R1GeneProductPIK3R1 (HGNC)
PIK3R2GeneProductPIK3R2 (HGNC)
PIK3R3GeneProductPIK3R3 (HGNC)
PIM1GeneProductPIM1 (HGNC)
PIM2GeneProductPIM2 (HGNC)
PIP3MetaboliteC05981 (KEGG Compound)
PLCB1GeneProductPLCB1 (HGNC)
PLCB2GeneProductPLCB2 (HGNC)
PLCB3GeneProductPLCB3 (HGNC)
PLCB4GeneProductPLCB4 (HGNC)
PLCG1GeneProductPLCG1 (HGNC)
PLCG2GeneProductPLCG2 (HGNC)
PLD1GeneProductPLD1 (HGNC)
PLD2GeneProductPLD2 (HGNC)
PLEKHG5GeneProductPLEKHG5 (HGNC)
PMAIP1GeneProductPMAIP1 (HGNC)
PMLGeneProductPML (HGNC)
POLKGeneProductPOLK (HGNC)
PPAR signaling pathwayPathwayWP3942 (WikiPathways)
PPARDGeneProductPPARD (HGNC)
PPARGGeneProductPPARG (HGNC)
PRKACAGeneProductPRKACA (HGNC)
PRKACBGeneProductPRKACB (HGNC)
PRKACGGeneProductPRKACG (HGNC)
PRKCAGeneProductPRKCA (HGNC)
PRKCBGeneProductPRKCB (HGNC)
PRKCGGeneProductPRKCG (HGNC)
PTCH1GeneProductPTCH1 (HGNC)
PTCH2GeneProductPTCH2 (HGNC)
PTENGeneProductPTEN (HGNC)
PTGER1GeneProductPTGER1 (HGNC)
PTGER2GeneProductPTGER2 (HGNC)
PTGER3GeneProductPTGER3 (HGNC)
PTGER4GeneProductPTGER4 (HGNC)
PTGS2GeneProductPTGS2 (HGNC)
PTK2GeneProductPTK2 (HGNC)
ProgesteroneMetaboliteHMDB01830 (HMDB)
RAC1GeneProductRAC1 (HGNC)
RAC2GeneProduct5880 (Entrez Gene)
RAC3GeneProductRAC3 (HGNC)
RAD51GeneProductRAD51 (HGNC)
RAF1GeneProductRAF1 (HGNC)
RALAGeneProductRALA (HGNC)
RALBP1GeneProductRALBP1 (HGNC)
RALBGeneProductRALB (HGNC)
RALGDSGeneProductRALGDS (HGNC)
RARAGeneProductRARA (HGNC)
RARBGeneProductRARB (HGNC)
RASGRP1GeneProductRASGRP1 (HGNC)
RASGRP2GeneProductRASGRP2 (HGNC)
RASGRP3GeneProductRASGRP3 (HGNC)
RASGRP4GeneProductRASGRP4 (HGNC)
RASSF1GeneProductRASSF1 (HGNC)
RASSF5GeneProductRASSF5 (HGNC)
RB1GeneProductRB1 (HGNC)
RBX1GeneProductRBX1 (HGNC)
RELAGeneProductRELA (HGNC)
RETGeneProductRET (HGNC)
RHOAGeneProductRHOA (HGNC)
ROCK1GeneProductROCK1 (HGNC)
ROCK2GeneProductROCK2 (HGNC)
RPS6KA5GeneProductRPS6KA5 (HGNC)
RPS6KB1GeneProductRPS6KB1 (HGNC)
RPS6KB2GeneProductRPS6KB2 (HGNC)
RUNX1GeneProductRUNX1 (HGNC)
RUNX1T1GeneProductRUNX1T1 (HGNC)
RXRAGeneProductRXRA (HGNC)
RXRBGeneProductRXRB (HGNC)
RXRGGeneProductRXRG (HGNC)
Retinoic AcidMetaboliteCHEBI:15367 (ChEBI)
SHHGeneProductSHH (HGNC)
SKP1GeneProductSKP1 (HGNC)
SKP2GeneProductSKP2 (HGNC)
SLC2A1GeneProductSLC2A1 (HGNC)
SMAD2GeneProductSMAD2 (HGNC)
SMAD3GeneProductSMAD3 (HGNC)
SMAD4GeneProductSMAD4 (HGNC)
SMOGeneProductSMO (HGNC)
SOS1GeneProductSOS1 (HGNC)
SOS2GeneProductSOS2 (HGNC)
SP1GeneProductENSG00000185591 (Ensembl)
SPI1GeneProductSPI1 (HGNC)
STAT1GeneProductSTAT1 (HGNC)
STAT2GeneProductSTAT2 (HGNC)
STAT3GeneProductSTAT3 (HGNC)
STAT4GeneProductSTAT4 (HGNC)
STAT5AGeneProductSTAT5A (HGNC)
STAT5BGeneProductSTAT5B (HGNC)
STAT6GeneProductSTAT6 (HGNC)
SUFUGeneProductSUFU (HGNC)
SuperoxideMetaboliteHMDB02168 (HMDB)
TCF7L1GeneProductTCF7L1 (HGNC)
TCF7L2GeneProductTCF7L2 (HGNC)
TCF7GeneProductTCF7 (HGNC)
TERCGeneProductTERC (HGNC)
TERTGeneProductTERT (HGNC)
TFGGeneProductTFG (HGNC)
TGF-beta signaling pathwayPathwayWP560 (WikiPathways)
TGFAGeneProductTGFA (HGNC)
TGFB1GeneProductTGFB1 (HGNC)
TGFB2GeneProductTGFB2 (HGNC)
TGFB3GeneProductTGFB3 (HGNC)
TGFBR1GeneProductTGFBR1 (HGNC)
TGFBR2GeneProductTGFBR2 (HGNC)
TP53GeneProductTP53 (HGNC)
TPM3GeneProductTPM3 (HGNC)
TPRGeneProductTPR (HGNC)
TRAF1GeneProductTRAF1 (HGNC)
TRAF2GeneProductTRAF2 (HGNC)
TRAF3GeneProductTRAF3 (HGNC)
TRAF4GeneProductTRAF4 (HGNC)
TRAF5GeneProductTRAF5 (HGNC)
TRAF6GeneProductTRAF6 (HGNC)
TXNRD1GeneProductTXNRD1 (HGNC)
TXNRD2GeneProductTXNRD2 (HGNC)
TXNRD3GeneProductTXNRD3 (HGNC)
TestosteroneMetaboliteHMDB00234 (HMDB)
VEGF signaling pathwayPathwayWP3888 (WikiPathways)
VEGFAGeneProductVEGFA (HGNC)
VEGFBGeneProductVEGFB (HGNC)
VEGFCGeneProductVEGFC (HGNC)
VEGFDGeneProductVEGFD (HGNC)
VHLGeneProductVHL (HGNC)
WNT10AGeneProductWNT10A (HGNC)
WNT10BGeneProductWNT10B (HGNC)
WNT11GeneProductWNT11 (HGNC)
WNT16GeneProductWNT16 (HGNC)
WNT1GeneProductWNT1 (HGNC)
WNT2BGeneProductWNT2B (HGNC)
WNT2GeneProductWNT2 (HGNC)
WNT3AGeneProductWNT3A (HGNC)
WNT3GeneProductWNT3 (HGNC)
WNT4GeneProductWNT4 (HGNC)
WNT5AGeneProductWNT5A (HGNC)
WNT5BGeneProductWNT5B (HGNC)
WNT6GeneProductWNT6 (HGNC)
WNT7AGeneProductWNT7A (HGNC)
WNT7BGeneProductWNT7B (HGNC)
WNT8AGeneProductWNT8A (HGNC)
WNT8BGeneProductWNT8B (HGNC)
WNT9AGeneProductWNT9A (HGNC)
WNT9BGeneProductWNT9B (HGNC)
Wnt signaling pathwayPathwayWP428 (WikiPathways)
XIAPGeneProductXIAP (HGNC)
ZBTB16GeneProductZBTB16 (HGNC)
ZBTB17GeneProductZBTB17 (HGNC)
cAMP signaling pathwayPathway
cAMPMetaboliteCHEBI:17489 (ChEBI)
fumarateMetaboliteCHEBI:29806 (ChEBI)
mTOR signaling pathwayPathwayWP3932 (WikiPathways)
p53 signaling pathwayPathway

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5434"
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